-
1
-
-
67650899072
-
Mesencephalic astrocyte-derived neurotrophic factor reduces ischemic brain injury and promotes behavioral recovery in rats
-
Airavaara M., Shen H., Kuo C.C., Peränen J., Saarma M., Hoffer B., Wang Y. Mesencephalic astrocyte-derived neurotrophic factor reduces ischemic brain injury and promotes behavioral recovery in rats. J.Comp. Neurol. 2009, 515:116-124.
-
(2009)
J.Comp. Neurol.
, vol.515
, pp. 116-124
-
-
Airavaara, M.1
Shen, H.2
Kuo, C.C.3
Peränen, J.4
Saarma, M.5
Hoffer, B.6
Wang, Y.7
-
2
-
-
47349130525
-
Armet, a UPR-upregulated protein, inhibits cell proliferation and ER stress-induced cell death
-
Apostolou A., Shen Y., Liang Y., Luo J., Fang S. Armet, a UPR-upregulated protein, inhibits cell proliferation and ER stress-induced cell death. Exp. Cell Res. 2008, 314:2454-2467.
-
(2008)
Exp. Cell Res.
, vol.314
, pp. 2454-2467
-
-
Apostolou, A.1
Shen, Y.2
Liang, Y.3
Luo, J.4
Fang, S.5
-
3
-
-
77957583357
-
MafA and MafB regulate genes critical to beta-cells in a unique temporal manner
-
Artner I., Hang Y., Mazur M., Yamamoto T., Guo M., Lindner J., Magnuson M.A., Stein R. MafA and MafB regulate genes critical to beta-cells in a unique temporal manner. Diabetes 2010, 59:2530-2539.
-
(2010)
Diabetes
, vol.59
, pp. 2530-2539
-
-
Artner, I.1
Hang, Y.2
Mazur, M.3
Yamamoto, T.4
Guo, M.5
Lindner, J.6
Magnuson, M.A.7
Stein, R.8
-
4
-
-
84866166023
-
MANF regulates dopaminergic neuron development in larval zebrafish
-
Chen Y.C., Sundvik M., Rozov S., Priyadarshini M., Panula P. MANF regulates dopaminergic neuron development in larval zebrafish. Dev. Biol. 2012, 370:237-249.
-
(2012)
Dev. Biol.
, vol.370
, pp. 237-249
-
-
Chen, Y.C.1
Sundvik, M.2
Rozov, S.3
Priyadarshini, M.4
Panula, P.5
-
5
-
-
33947510911
-
Selective inhibition of eukaryotic translation initiation factor 2 alpha dephosphorylation potentiates fatty acid-induced endoplasmic reticulum stress and causes pancreatic beta-cell dysfunction and apoptosis
-
Cnop M., Ladriere L., Hekerman P., Ortis F., Cardozo A.K., Dogusan Z., Flamez D., Boyce M., Yuan J., Eizirik D.L. Selective inhibition of eukaryotic translation initiation factor 2 alpha dephosphorylation potentiates fatty acid-induced endoplasmic reticulum stress and causes pancreatic beta-cell dysfunction and apoptosis. J.Biol. Chem. 2007, 282:3989-3997.
-
(2007)
J.Biol. Chem.
, vol.282
, pp. 3989-3997
-
-
Cnop, M.1
Ladriere, L.2
Hekerman, P.3
Ortis, F.4
Cardozo, A.K.5
Dogusan, Z.6
Flamez, D.7
Boyce, M.8
Yuan, J.9
Eizirik, D.L.10
-
6
-
-
0345736922
-
Nestin expression in pancreatic exocrine cell lineages
-
Delacour A., Nepote V., Trumpp A., Herrera P.L. Nestin expression in pancreatic exocrine cell lineages. Mech. Dev. 2004, 121:3-14.
-
(2004)
Mech. Dev.
, vol.121
, pp. 3-14
-
-
Delacour, A.1
Nepote, V.2
Trumpp, A.3
Herrera, P.L.4
-
7
-
-
0034425698
-
EIF2AK3, encoding translation initiation factor 2-alpha kinase 3, is mutated in patients with Wolcott-Rallison syndrome
-
Delépine M., Nicolino M., Barrett T., Golamaully M., Lathrop G.M., Julier C. EIF2AK3, encoding translation initiation factor 2-alpha kinase 3, is mutated in patients with Wolcott-Rallison syndrome. Nat. Genet. 2000, 25:406-409.
-
(2000)
Nat. Genet.
, vol.25
, pp. 406-409
-
-
Delépine, M.1
Nicolino, M.2
Barrett, T.3
Golamaully, M.4
Lathrop, G.M.5
Julier, C.6
-
9
-
-
1842844414
-
Decreased beta-cell mass in diabetes: significance, mechanisms and therapeutic implications
-
Donath M.Y., Halban P.A. Decreased beta-cell mass in diabetes: significance, mechanisms and therapeutic implications. Diabetologia 2004, 47:581-589.
-
(2004)
Diabetologia
, vol.47
, pp. 581-589
-
-
Donath, M.Y.1
Halban, P.A.2
-
10
-
-
39149104320
-
The role for endoplasmic reticulum stress in diabetes mellitus
-
Eizirik D.L., Cardozo A.K., Cnop M. The role for endoplasmic reticulum stress in diabetes mellitus. Endocr. Rev. 2008, 29:42-61.
-
(2008)
Endocr. Rev.
, vol.29
, pp. 42-61
-
-
Eizirik, D.L.1
Cardozo, A.K.2
Cnop, M.3
-
11
-
-
84878777666
-
Signalling danger: endoplasmic reticulum stress and the unfolded protein response in pancreatic islet inflammation
-
Eizirik D.L., Miani M., Cardozo A.K. Signalling danger: endoplasmic reticulum stress and the unfolded protein response in pancreatic islet inflammation. Diabetologia 2013, 56:234-241.
-
(2013)
Diabetologia
, vol.56
, pp. 234-241
-
-
Eizirik, D.L.1
Miani, M.2
Cardozo, A.K.3
-
12
-
-
84864385242
-
Mesencephalic astrocyte-derived neurotrophic factor protects the heart from ischemic damage and is selectively secreted upon sarco/endoplasmic reticulum calcium depletion
-
Glembotski C.C., Thuerauf D.J., Huang C., Vekich J.A., Gottlieb R.A., Doroudgar S. Mesencephalic astrocyte-derived neurotrophic factor protects the heart from ischemic damage and is selectively secreted upon sarco/endoplasmic reticulum calcium depletion. J.Biol. Chem. 2012, 287:25893-25904.
-
(2012)
J.Biol. Chem.
, vol.287
, pp. 25893-25904
-
-
Glembotski, C.C.1
Thuerauf, D.J.2
Huang, C.3
Vekich, J.A.4
Gottlieb, R.A.5
Doroudgar, S.6
-
13
-
-
78951481383
-
Mesencephalic astrocyte-derived neurotrophic factor (MANF) has a unique mechanism to rescue apoptotic neurons
-
Hellman M., Arumäe U., Yu L.Y., Lindholm P., Peränen J., Saarma M., Permi P. Mesencephalic astrocyte-derived neurotrophic factor (MANF) has a unique mechanism to rescue apoptotic neurons. J.Biol. Chem. 2011, 286:2675-2680.
-
(2011)
J.Biol. Chem.
, vol.286
, pp. 2675-2680
-
-
Hellman, M.1
Arumäe, U.2
Yu, L.Y.3
Lindholm, P.4
Peränen, J.5
Saarma, M.6
Permi, P.7
-
14
-
-
84856111924
-
The unfolded protein response: controlling cell fate decisions under ER stress and beyond
-
Hetz C. The unfolded protein response: controlling cell fate decisions under ER stress and beyond. Nat. Rev. Mol. Cell Biol. 2012, 13:89-102.
-
(2012)
Nat. Rev. Mol. Cell Biol.
, vol.13
, pp. 89-102
-
-
Hetz, C.1
-
15
-
-
77949691167
-
Novel CDNF/MANF family of neurotrophic factors
-
Lindholm P., Saarma M. Novel CDNF/MANF family of neurotrophic factors. Dev. Neurobiol. 2010, 70:360-371.
-
(2010)
Dev. Neurobiol.
, vol.70
, pp. 360-371
-
-
Lindholm, P.1
Saarma, M.2
-
16
-
-
34447132381
-
Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons invivo
-
Lindholm P., Voutilainen M.H., Laurén J., Peränen J., Leppänen V.M., Andressoo J.O., Lindahl M., Janhunen S., Kalkkinen N., Timmusk T., et al. Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons invivo. Nature 2007, 448:73-77.
-
(2007)
Nature
, vol.448
, pp. 73-77
-
-
Lindholm, P.1
Voutilainen, M.H.2
Laurén, J.3
Peränen, J.4
Leppänen, V.M.5
Andressoo, J.O.6
Lindahl, M.7
Janhunen, S.8
Kalkkinen, N.9
Timmusk, T.10
-
17
-
-
53849102168
-
MANF is widely expressed in mammalian tissues and differently regulated after ischemic and epileptic insults in rodent brain
-
Lindholm P., Peränen J., Andressoo J.O., Kalkkinen N., Kokaia Z., Lindvall O., Timmusk T., Saarma M. MANF is widely expressed in mammalian tissues and differently regulated after ischemic and epileptic insults in rodent brain. Mol. Cell. Neurosci. 2008, 39:356-371.
-
(2008)
Mol. Cell. Neurosci.
, vol.39
, pp. 356-371
-
-
Lindholm, P.1
Peränen, J.2
Andressoo, J.O.3
Kalkkinen, N.4
Kokaia, Z.5
Lindvall, O.6
Timmusk, T.7
Saarma, M.8
-
18
-
-
44749088201
-
Beta-cell replication is the primary mechanism subserving the postnatal expansion of beta-cell mass in humans
-
Meier J.J., Butler A.E., Saisho Y., Monchamp T., Galasso R., Bhushan A., Rizza R.A., Butler P.C. Beta-cell replication is the primary mechanism subserving the postnatal expansion of beta-cell mass in humans. Diabetes 2008, 57:1584-1594.
-
(2008)
Diabetes
, vol.57
, pp. 1584-1594
-
-
Meier, J.J.1
Butler, A.E.2
Saisho, Y.3
Monchamp, T.4
Galasso, R.5
Bhushan, A.6
Rizza, R.A.7
Butler, P.C.8
-
19
-
-
33845534764
-
Downregulation of EGF receptor signaling in pancreatic islets causes diabetes due to impaired postnatal beta-cell growth
-
Miettinen P.J., Ustinov J., Ormio P., Gao R., Palgi J., Hakonen E., Juntti-Berggren L., Berggren P.O., Otonkoski T. Downregulation of EGF receptor signaling in pancreatic islets causes diabetes due to impaired postnatal beta-cell growth. Diabetes 2006, 55:3299-3308.
-
(2006)
Diabetes
, vol.55
, pp. 3299-3308
-
-
Miettinen, P.J.1
Ustinov, J.2
Ormio, P.3
Gao, R.4
Palgi, J.5
Hakonen, E.6
Juntti-Berggren, L.7
Berggren, P.O.8
Otonkoski, T.9
-
20
-
-
34548450668
-
ARMET is a soluble ER protein induced by theunfolded protein response via ERSE-II element
-
Mizobuchi N., Hoseki J., Kubota H., Toyokuni S., Nozaki J., Naitoh M., Koizumi A., Nagata K. ARMET is a soluble ER protein induced by theunfolded protein response via ERSE-II element. Cell Struct. Funct. 2007, 32:41-50.
-
(2007)
Cell Struct. Funct.
, vol.32
, pp. 41-50
-
-
Mizobuchi, N.1
Hoseki, J.2
Kubota, H.3
Toyokuni, S.4
Nozaki, J.5
Naitoh, M.6
Koizumi, A.7
Nagata, K.8
-
21
-
-
60549115250
-
Evidence that DmMANF is an invertebrate neurotrophic factor supporting dopaminergic neurons
-
Palgi M., Lindström R., Peränen J., Piepponen T.P., Saarma M., Heino T.I. Evidence that DmMANF is an invertebrate neurotrophic factor supporting dopaminergic neurons. Proc. Natl. Acad. Sci. USA 2009, 106:2429-2434.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 2429-2434
-
-
Palgi, M.1
Lindström, R.2
Peränen, J.3
Piepponen, T.P.4
Saarma, M.5
Heino, T.I.6
-
22
-
-
84859498069
-
Gene expression analysis of Drosophilaa Manf mutants reveals perturbations in membrane traffic and major metabolic changes
-
Palgi M., Greco D., Lindström R., Auvinen P., Heino T.I. Gene expression analysis of Drosophilaa Manf mutants reveals perturbations in membrane traffic and major metabolic changes. BMC Genomics 2012, 13:134.
-
(2012)
BMC Genomics
, vol.13
, pp. 134
-
-
Palgi, M.1
Greco, D.2
Lindström, R.3
Auvinen, P.4
Heino, T.I.5
-
23
-
-
0037942718
-
MANF: a new mesencephalic, astrocyte-derived neurotrophic factor with selectivity for dopaminergic neurons
-
Petrova P., Raibekas A., Pevsner J., Vigo N., Anafi M., Moore M.K., Peaire A.E., Shridhar V., Smith D.I., Kelly J., et al. MANF: a new mesencephalic, astrocyte-derived neurotrophic factor with selectivity for dopaminergic neurons. J.Mol. Neurosci. 2003, 20:173-188.
-
(2003)
J.Mol. Neurosci.
, vol.20
, pp. 173-188
-
-
Petrova, P.1
Raibekas, A.2
Pevsner, J.3
Vigo, N.4
Anafi, M.5
Moore, M.K.6
Peaire, A.E.7
Shridhar, V.8
Smith, D.I.9
Kelly, J.10
-
24
-
-
47949127583
-
Endoplasmic reticulum stress-induced activation of activating transcription factor 6 decreases insulin gene expression via up-regulation of orphan nuclear receptor small heterodimer partner
-
Seo H.Y., Kim Y.D., Lee K.M., Min A.K., Kim M.K., Kim H.S., Won K.C., Park J.Y., Lee K.U., Choi H.S., et al. Endoplasmic reticulum stress-induced activation of activating transcription factor 6 decreases insulin gene expression via up-regulation of orphan nuclear receptor small heterodimer partner. Endocrinology 2008, 149:3832-3841.
-
(2008)
Endocrinology
, vol.149
, pp. 3832-3841
-
-
Seo, H.Y.1
Kim, Y.D.2
Lee, K.M.3
Min, A.K.4
Kim, M.K.5
Kim, H.S.6
Won, K.C.7
Park, J.Y.8
Lee, K.U.9
Choi, H.S.10
-
25
-
-
33748789479
-
Mediators ofendoplasmic reticulum stress-induced apoptosis
-
Szegezdi E., Logue S.E., Gorman A.M., Samali A. Mediators ofendoplasmic reticulum stress-induced apoptosis. EMBO Rep. 2006, 7:880-885.
-
(2006)
EMBO Rep.
, vol.7
, pp. 880-885
-
-
Szegezdi, E.1
Logue, S.E.2
Gorman, A.M.3
Samali, A.4
-
26
-
-
84866389264
-
Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure
-
Talchai C., Xuan S., Lin H.V., Sussel L., Accili D. Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure. Cell 2012, 150:1223-1234.
-
(2012)
Cell
, vol.150
, pp. 1223-1234
-
-
Talchai, C.1
Xuan, S.2
Lin, H.V.3
Sussel, L.4
Accili, D.5
-
27
-
-
84861054514
-
A simple matter of life and death-the trials of postnatal Beta-cell mass regulation
-
Tarabra E., Pelengaris S., Khan M. A simple matter of life and death-the trials of postnatal Beta-cell mass regulation. Int. J. Endocrinol. 2012, 2012:516718.
-
(2012)
Int. J. Endocrinol.
, vol.2012
, pp. 516718
-
-
Tarabra, E.1
Pelengaris, S.2
Khan, M.3
-
28
-
-
33644835007
-
Growth factors and beta cell replication
-
Vasavada R.C., Gonzalez-Pertusa J.A., Fujinaka Y., Fiaschi-Taesch N., Cozar-Castellano I., Garcia-Ocaña A. Growth factors and beta cell replication. Int. J. Biochem. Cell Biol. 2006, 38:931-950.
-
(2006)
Int. J. Biochem. Cell Biol.
, vol.38
, pp. 931-950
-
-
Vasavada, R.C.1
Gonzalez-Pertusa, J.A.2
Fujinaka, Y.3
Fiaschi-Taesch, N.4
Cozar-Castellano, I.5
Garcia-Ocaña, A.6
-
29
-
-
68049127516
-
Mesencephalic astrocyte-derived neurotrophic factor is neurorestorative in rat model of Parkinson's disease
-
Voutilainen M.H., Bäck S., Pörsti E., Toppinen L., Lindgren L., Lindholm P., Peränen J., Saarma M., Tuominen R.K. Mesencephalic astrocyte-derived neurotrophic factor is neurorestorative in rat model of Parkinson's disease. J.Neurosci. 2009, 29:9651-9659.
-
(2009)
J.Neurosci.
, vol.29
, pp. 9651-9659
-
-
Voutilainen, M.H.1
Bäck, S.2
Pörsti, E.3
Toppinen, L.4
Lindgren, L.5
Lindholm, P.6
Peränen, J.7
Saarma, M.8
Tuominen, R.K.9
-
30
-
-
82255173966
-
The unfolded protein response: from stress pathway to homeostatic regulation
-
Walter P., Ron D. The unfolded protein response: from stress pathway to homeostatic regulation. Science 2011, 334:1081-1086.
-
(2011)
Science
, vol.334
, pp. 1081-1086
-
-
Walter, P.1
Ron, D.2
-
31
-
-
84885044818
-
Mice lacking ANGPTL8 (Betatrophin) manifest disrupted triglyceride metabolism without impaired glucose homeostasis
-
Wang Y., Quagliarini F., Gusarova V., Gromada J., Valenzuela D.M., Cohen J.C., Hobbs H.H. Mice lacking ANGPTL8 (Betatrophin) manifest disrupted triglyceride metabolism without impaired glucose homeostasis. Proc. Natl. Acad. Sci. USA 2013, 110:16109-16114.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 16109-16114
-
-
Wang, Y.1
Quagliarini, F.2
Gusarova, V.3
Gromada, J.4
Valenzuela, D.M.5
Cohen, J.C.6
Hobbs, H.H.7
-
32
-
-
84875684003
-
Islet β cell mass in diabetes and how it relates to function, birth, and death
-
Weir G.C., Bonner-Weir S. Islet β cell mass in diabetes and how it relates to function, birth, and death. Ann. N Y Acad. Sci. 2013, 1281:92-105.
-
(2013)
Ann. N Y Acad. Sci.
, vol.1281
, pp. 92-105
-
-
Weir, G.C.1
Bonner-Weir, S.2
-
33
-
-
84877707122
-
Betatrophin: a hormone that controls pancreatic β cell proliferation
-
Yi P., Park J.S., Melton D.A. Betatrophin: a hormone that controls pancreatic β cell proliferation. Cell 2013, 153:747-758.
-
(2013)
Cell
, vol.153
, pp. 747-758
-
-
Yi, P.1
Park, J.S.2
Melton, D.A.3
|