Biomimetic design of platelet adhesion inhibitors to block integrin α2β1-collagen interactions: II. Inhibitor library, screening, and experimental validation

Langmuir

Volumn 30, Issue 16, 2014, Pages 4734-4742

  Zhang, Lin ^a,b   Zhang, Chao ^a,b   Sun, Yan ^a,b  

^a TIANJIN UNIVERSITY   (China)

^b SynBio Research Platform   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESION; BINDING ENERGY; BIOMIMETICS; COLLAGEN; MOLECULAR DYNAMICS;

BINDING AFFINITIES; COLLAGEN MOLECULES; EXPERIMENTAL VALIDATIONS; ISOTHERMAL TITRATION CALORIMETRY; MOLECULAR DYNAMICS SIMULATIONS; ORIGINAL STRUCTURES; PHYSIOLOGICAL SALINE; STRUCTURE SIMILARITY;

STRUCTURAL DESIGN;

COLLAGEN; PLASMA PROTEIN; PLATELET ADHESION INHIBITOR; PROTEIN BINDING; VERY LATE ACTIVATION ANTIGEN 2;

BIOMIMETICS; CHEMICAL PHENOMENA; CHEMISTRY; MOLECULAR DYNAMICS; PROCEDURES;

BIOMIMETICS; BLOOD PROTEINS; COLLAGEN; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; INTEGRIN ALPHA2BETA1; MOLECULAR DYNAMICS SIMULATION; PROTEIN BINDING;

EID: 84899621119     PISSN: 07437463     EISSN: 15205827     Source Type: Journal    
DOI: 10.1021/la4046012     Document Type: Article

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