Generation of mouse induced pluripotent stem cells by protein transduction

Tissue Engineering - Part C: Methods

Volumn 20, Issue 5, 2014, Pages 383-392

  Nemes, Csilla ^a   Varga, Eszter ^a,b   Polgar, Zsuzsanna ^a   Klincumhom, Nuttha ^a,d   Pirity, Melinda K ^a   Dinnyes, Andras ^a,b,c,e  

^a BIOTALENTUM LTD   (Hungary)

^b SZENT ISTVÁN UNIVERSITY   (Hungary)

^c UTRECHT UNIVERSITY   (Netherlands)

^d MAHIDOL UNIVERSITY   (Thailand)

^e INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIOPHAGES; CELL CULTURE; FIBROBLASTS; GENE TRANSFER; MAMMALS; PURIFICATION; STEM CELLS; TRANSCRIPTION;

AFFINITY PURIFICATION; EMBRYONIC FIBROBLASTS; GENE DELIVERY SYSTEMS; GLUTATHIONE-S-TRANSFERASE; INDUCED PLURIPOTENT STEM CELLS; MOUSE EMBRYONIC FIBROBLASTS; NUCLEAR LOCALIZATION; REVERSE TRANSCRIPTION-POLYMERASE CHAIN REACTION;

RECOMBINANT PROTEINS;

GLUTATHIONE TRANSFERASE; KRUPPEL LIKE FACTOR 4; MITOMYCIN; MYC PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; RECOMBINANT PROTEIN; SIGNAL PEPTIDE; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2; TRANSCRIPTION FACTOR;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLASTOCYST; CELL DIFFERENTIATION; CELL GROWTH; CELL LINE; CELL MEMBRANE PERMEABILITY; CELL STRUCTURE; CHIMERA; CONTROLLED STUDY; ECTODERM; EMBRYO; EMBRYOID BODY; EMBRYONIC STEM CELL; ENDODERM; FIBROBLAST; GENE DELIVERY SYSTEM; GENE EXPRESSION; GENETIC TRANSDUCTION; GENOME; GERM LAYER; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; INBRED MOUSE STRAIN; MESODERM; MOUSE; NEURAL STEM CELL; NEWBORN; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; NUCLEAR REPROGRAMMING; OUTBRED MOUSE STRAIN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RISK; SOMATIC CELL; TARGET CELL; ANIMAL; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; ISOLATION AND PURIFICATION; METABOLISM; PROCEDURES; REPRODUCIBILITY;

ANIMALS; CELL DIFFERENTIATION; CHIMERA; GENE EXPRESSION REGULATION; INDUCED PLURIPOTENT STEM CELLS; MICE; RECOMBINANT PROTEINS; REPRODUCIBILITY OF RESULTS; TRANSCRIPTION FACTORS; TRANSDUCTION, GENETIC;

EID: 84899536183     PISSN: 19373384     EISSN: 19373392     Source Type: Journal    
DOI: 10.1089/ten.tec.2013.0026     Document Type: Article

References (61)

1. Takahashi, K., and Yamanaka, S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126, 663, 2006.
2. Lowry, W.E., et al. Generation of human induced pluripotent stem cells from dermal fibroblasts. Proc Natl Acad Sci U S A 105, 2883, 2008.
3. Park, I.H., et al. Reprogramming of human somatic cells to pluripotency with defined factors. Nature 451, 141, 2008.
4. Yu, J., et al. Induced pluripotent stem cell lines derived from human somatic cells. Science 318, 1917, 2007.
5. Maherali, N., et al. Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell 1, 55, 2007.
6. Okita, K., Ichisaka, T., and Yamanaka, S. Generation of germline-competent induced pluripotent stem cells. Nature 448, 313, 2007.
7. Wernig, M., et al. In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state. Nature 448, 318, 2007.
8. Li, W., et al. Generation of rat and human induced pluripotent stem cells by combining genetic reprogramming and chemical inhibitors. Cell Stem Cell 4, 16, 2009.
9. Montserrat, N., et al. Generation of pig iPS cells: a model for cell therapy. J Cardiovasc Transl Res 4, 121, 2011.
10. Wu, Z., et al. Generation of pig induced pluripotent stem cells with a drug-inducible system. J Mol Cell Biol 1, 46, 2009.
11. Li, Y., et al. Reprogramming of sheep fibroblasts into pluripotency under a drug-inducible expression of mousederived defined factors. PLoS One 6, p. e15947, 2011.
12. Liu, J., et al. Generation and characterization of reprogrammed sheep induced pluripotent stem cells. Theriogenology 77, 338 e1, 2012.
13. Honda, A., et al. Generation of induced pluripotent stem cells in rabbits: potential experimental models for human regenerative medicine. J Biol Chem 285, 31362, 2010.
14. Hanna, J., et al. Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin. Science 318, 1920, 2007.
15. Seki, T., et al. Generation of induced pluripotent stem cells from human terminally differentiated circulating T cells. Cell Stem Cell 7, 11, 2010.
16. Aoi, T., et al. Generation of pluripotent stem cells from adult mouse liver and stomach cells. Science 321, 699, 2008.
17. Kim, J.B., et al. Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors. Nature 454, 646, 2008.
18. Aasen, T., et al. Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes. Nat Biotechnol 26, 1276, 2008.
19. Utikal, J., et al. Sox2 is dispensable for the reprogramming of melanocytes and melanoma cells into induced pluripotent stem cells. J Cell Sci 122, 3502, 2009.
20. Stadtfeld, M., Brennand, K., and Hochedlinger, K. Reprogramming of pancreatic beta cells into induced pluripotent stem cells. Curr Biol 18, 890, 2008.
21. Jalving, M., and Schepers, H. Induced pluripotent stem cells: will they be safe? Curr Opin Mol Ther 11, 383, 2009.
22. Woltjen, K., et al. piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells. Nature 458, 766, 2009.
23. Yusa, K., et al. Generation of transgene-free induced pluripotent mouse stem cells by the piggyBac transposon. Nat Methods 6, 363, 2009.
24. Muenthaisong, S., et al. Generation of mouse induced pluripotent stem cells from different genetic backgrounds using Sleeping beauty transposon mediated gene transfer. Exp Cell Res 318, 2482, 2012.
25. Okita, K., et al. Generation of mouse induced pluripotent stem cells without viral vectors. Science 322, 949, 2008.
26. Anokye-Danso, F., et al. Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency. Cell Stem Cell 8, 376, 2011.
27. Jia, F., et al. A nonviral minicircle vector for deriving human iPS cells. Nat Methods 7, 197, 2010.
28. Narsinh, K.H., et al. Generation of adult human induced pluripotent stem cells using nonviral minicircle DNA vectors. Nat Protoc 6, 78, 2011.
29. Yu, J., et al. Human induced pluripotent stem cells free of vector and transgene sequences. Science 324, 797, 2009.
30. Bosch, P., et al. Efficient adenoviral-mediated gene delivery into porcine mesenchymal stem cells. Mol Reprod Dev 73, 1393, 2006.
31. Stadtfeld, M., et al. Induced pluripotent stem cells generated without viral integration. Science 322, 945, 2008.
32. Suzuki, K., et al. Highly efficient transient gene expression and gene targeting in primate embryonic stem cells with helper-dependent adenoviral vectors. Proc Natl Acad Sci U S A 105, 13781, 2008.
33. Tashiro, K., et al. Adenovirus vector-mediated efficient transduction into human embryonic and induced pluripotent stem cells. Cell Reprogram 12, 501, 2010.
34. Zhou, W., and Freed, C.R. Adenoviral gene delivery can reprogram human fibroblasts to induced pluripotent stem cells. Stem Cells 27, 2667, 2009.
35. Ban, H., et al. Efficient generation of transgene-free human induced pluripotent stem cells (iPSCs) by temperaturesensitive Sendai virus vectors. Proc Natl Acad Sci U S A 108, 14234, 2011.
36. Nishimura, K., et al. Development of defective and persistent Sendai virus vector: a unique gene delivery/expression system ideal for cell reprogramming. J Biol Chem 286, 4760, 2011.
37. Huangfu, D., et al. Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2. Nat Biotechnol 26, 1269, 2008.
38. Ichida, J.K., et al. A small-molecule inhibitor of tgf-Beta signaling replaces sox2 in reprogramming by inducing nanog. Cell Stem Cell 5, 491, 2009.
39. Mali, P., et al. Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes. Stem Cells 28, 713, 2010.
40. Shi, Y., et al. Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds. Cell Stem Cell 3, 568, 2008.
41. Yuan, X., et al. Brief report: combined chemical treatment enables Oct4-induced reprogramming from mouse embryonic fibroblasts. Stem Cells 29, 549, 2011.
42. Warren, L., et al. Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell Stem Cell 7, 618, 2010.
43. Yakubov, E., et al. Reprogramming of human fibroblasts to pluripotent stem cells using mRNA of four transcription factors. Biochem Biophys Res Commun 394, 189, 2010.
44. Kim, D., et al. Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins. Cell Stem Cell 4, 472, 2009.
45. Zhou, H., et al. Generation of induced pluripotent stem cells using recombinant proteins. Cell Stem Cell 4, 381, 2009.
46. Zhang, H., et al. Reprogramming of somatic cells via TATmediated protein transduction of recombinant factors. Biomaterials 33, 5047, 2012.
47. Gonzalez, F., Boue, S., and Izpisua Belmonte, J.C. Methods for making induced pluripotent stem cells: reprogramming a la carte. Nat Rev Genet 12, 231, 2011.
48. Beerens, A.M., et al. Protein transduction domains and their utility in gene therapy. Curr Gene Ther 3, 486, 2003.
49. Frankel, A.D., and Pabo, C.O. Cellular uptake of the tat protein from human immunodeficiency virus. Cell 55, 1189, 1988.
50. Kalderon, D., et al. A short amino acid sequence able to specify nuclear location. Cell 39, 499, 1984.
51. Madani, F., et al. Mechanisms of cellular uptake of cellpenetrating peptides. J Biophys 2011, 414729, 2011.
52. van den Berg, A., and Dowdy, S.F. Protein transduction domain delivery of therapeutic macromolecules. Curr Opin Biotechnol 22, 888, 2011.
53. Nakase, I., Kobayashi, S., and Futaki, S. Endosome-disruptive peptides for improving cytosolic delivery of bioactive macromolecules. Biopolymers 94, 763, 2010.
54. Neundorf, I., Rennert, R., Hoyer, J., Schramm, F., Löbner, K., Kitanovic, I., and Wölfl, S. Fusion of a short HA2-derived peptide sequence to cell-penetrating peptides improves cytosolic uptake, but enhances cytotoxic activity. Pharmaceuticals 2, 49, 2009.
55. Juriloff, D.M., and Harris, M.J. Mouse models for neural tube closure defects. Hum Mol Genet 9, 993, 2000.
56. Yoshida, Y., et al. Hypoxia enhances the generation of induced pluripotent stem cells. Cell Stem Cell 5, 237, 2009.
57. Bosnali, M., and Edenhofer, F. Generation of transducible versions of transcription factors Oct4 and Sox2. Biol Chem 389, 851, 2008.
58. Thier, M., Munst, B., and Edenhofer, F. Exploring refined conditions for reprogramming cells by recombinant Oct4 protein. Int J Dev Biol 54, 1713, 2010.
59. Thier, M., et al. Cellular reprogramming employing recombinant sox2 protein. Stem Cells Int 2012, 549846, 2012.
60. Radzisheuskaya, A., et al. A defined Oct4 level governs cell state transitions of pluripotency entry and differentiation into all embryonic lineages. Nat Cell Biol, 15, 579, 2013.
61. Martinez, Y., et al. Cellular diversity within embryonic stem cells: pluripotent clonal sublines show distinct differentiation potential. J Cell Mol Med 16, 456, 2012.