The novel diagnostic biomarkers for focal segmental glomerulosclerosis

International Journal of Nephrology

Volumn 2014, Issue , 2014, Pages

  Nafar, Mohsen ^a,b,c   Kalantari, Shiva ^c   Samavat, Shiva ^a,b,c   Rezaei Tavirani, Mostafa ^d   Rutishuser, Dorothea ^e,f   Zubarev, Roman A ^e,f  

^a SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^e KAROLINSKA INSTITUTE   (Sweden)

^f SCIENCE FOR LIFE LABORATORY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84899536017     PISSN: 2090214X     EISSN: 20902158     Source Type: Journal    
DOI: 10.1155/2014/574261     Document Type: Article

References (73)

1. Benchimol C., Focal segmental glomerulosclerosis: pathogenesis and treatment. Current Opinion in Pediatrics 2003 15 2 171 180 2-s2.0-0037376485 10.1097/00008480-200304000-00006
2. Fogo A. B., Animal models of FSGS: lessons for pathogenesis and treatment. Seminars in Nephrology 2003 23 2 161 171 2-s2.0-0037350930 10.1053/snep.2003.50015
3. D'Agati V. D., Kaskel F. J., Falk R. J., Focal segmental glomerulosclerosis. New England Journal of Medicine 2011 365 25 2398 2411 2-s2.0-84855183026 10.1056/NEJMra1106556
4. Schnaper H. W., Idiopathic focal segmental glomerulosclerosis. Seminars in Nephrology 2003 23 2 183 193 2-s2.0-0037350914 10.1053/snep.2003.50016
5. Kriz W., The pathogenesis of "classic" focal segmental glomerulosclerosis-lessons from rat models. Nephrology Dialysis Transplantation 2003 18 supplement 6 vi39 vi44 2-s2.0-0042384662
6. Asanuma K., Mundel P., The role of podocytes in glomerular pathobiology. Clinical and Experimental Nephrology 2003 7 4 255 259 2-s2.0-0346788786 10.1007/s10157-003-0259-6
7. Sever S., Trachtman H., Wei C., Reiser J., Is there clinical value in measuring suPAR levels in FSGS? Clinical Journal of the American Society of Nephrology 2013 8 8 1273 1275 10.2215/CJN.06170613
8. Wei C., El Hindi S., Li J., Fornoni A., Goes N., Sageshima J., Maiguel D., Karumanchi S. A., Yap H., Saleem M., Zhang Q., Nikolic B., Chaudhuri A., Daftarian P., Salido E., Torres A., Salifu M., Sarwal M. M., Schaefer F., Morath C., Schwenger V., Zeier M., Gupta V., Roth D., Rastaldi M. P., Burke G., Ruiz P., Reiser J., Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis. Nature Medicine 2011 17 8 952 960 2-s2.0-79961132981 10.1038/nm.2411
9. Wei C., Trachtman H., Li J., Circulating suPAR in two cohorts of primary FSGS. Journal of the American Society of Nephrology 2012 23 12 2051 2059 10.1681/ASN.2012030302
10. Jefferson A. J., Shankland S. J., Has the circulating permeability factor in primary FSGS been found? Kidney International 2013 84 235 238 10.1038/ki.2013.204
11. Kwoh C., Shannon M. B., Miner J. H., Shaw A., Pathogenesis of nonimmune glomeralopathies. Annual Review of Pathology 2006 1 349 374 2-s2.0-33645733358 10.1146/annurev.pathol.1.110304.100119
12. Van den Berg J. G., Weening J. J., Role of the immune system in the pathogenesis of idiopathic nephrotic syndrome. Clinical Science 2004 107 2 125 136 2-s2.0-4043090600 10.1042/CS20040095
13. Bruschi M., Candiano G., Ciana L. D., Petretto A., Santucci L., Prunotto M., Camilla R., Coppo R., Ghiggeri G. M., Analysis of the oxido-redox status of plasma proteins. Technology advances for clinical applications. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 2011 879 17-18 1338 1344 2-s2.0-79955621123 10.1016/j.jchromb.2010.11.030
14. Tsai P. Y., Ka S. M., Chao T. K., Chang J., Lin S., Li C., Kuo M., Chen P., Chen A., Antroquinonol reduces oxidative stress by enhancing the Nrf2 signaling pathway and inhibits inflammation and sclerosis in focal segmental glomerulosclerosis mice. Free Radical Biology and Medicine 2011 50 11 1503 1516 2-s2.0-79955575759 10.1016/j.freeradbiomed.2011.02.029
15. Benz K., Büttner M., Dittrich K., Campean V., Dötsch J., Amann K., Characterisation of renal immune cell infiltrates in children with nephrotic syndrome. Pediatric Nephrology 2010 25 7 1291 1298 2-s2.0-77954540690 10.1007/s00467-010-1507-0
16. Muñoz M., Rincón J., Pedreañez A., Viera N., Hernández-Fonseca J. P., Mosquera J., Proinflammatory role of angiotensin II in a rat nephrosis model induced by adriamycin. Journal of the Renin-Angiotensin-Aldosterone System 2011 12 4 404 412 2-s2.0-83455219479 10.1177/1470320311410092
17. Reidy K., Kaskel F. J., Pathophysiology of focal segmental glomerulosclerosis. Pediatric Nephrology 2007 22 3 350 354 2-s2.0-34248646767 10.1007/s00467-006-0357-2
18. D'Agati V., Pathologic classification of focal segmental glomerulosclerosis. Seminars in Nephrology 2003 23 2 117 134 2-s2.0-0037349392 10.1053/snep.2003.50012
19. Schnaper H. W., Idiopathic focal segmental glomerulosclerosis. Seminars in Nephrology 2003 23 2 183 193 2-s2.0-0037350914 10.1053/snep.2003.50016
20. Haubitz M., Wittke S., Weissinger E. M., Walden M., Rupprecht H. D., Floege J., Haller H., Mischak H., Urine protein patterns can serve as diagnostic tools in patients with IgA nephropathy. Kidney International 2005 67 6 2313 2320 2-s2.0-23044462246 10.1111/j.1523-1755.2005.00335.x
21. Mosley K., Tam F. W. K., Edwards R. J., Crozier J., Pusey C. D., Lightstone L., Urinary proteomic profiles distinguish between active and inactive lupus nephritis. Rheumatology 2006 45 12 1497 1504 2-s2.0-33751412843 10.1093/rheumatology/kel351
22. Thongboonkerd V., Klein J. B., Jevans A. W., McLeish K. R., Urinary proteomics and biomarker discovery for glomerular diseases. Contributions to Nephrology 2004 141 292 307 2-s2.0-4444382714
23. Xu B. J., Shyr Y., Liang X., Ma L., Donnert E. M., Roberts J. D., Zhang X., Kon V., Brown N. J., Caprioli R. M., Fogo A. B., Proteomic patterns and prediction of glomerulosclerosis and its mechanisms. Journal of the American Society of Nephrology 2005 16 10 2967 2975 2-s2.0-31544463826 10.1681/ASN.2005030262
24. Varghese S. A., Powell T. B., Budisavljevic M. N., Oates J. C., Raymond J. R., Almeida J. S., Arthur J. M., Urine biomarkers predict the cause of glomerular disease. Journal of the American Society of Nephrology 2007 18 3 913 922 2-s2.0-33947270262 10.1681/ASN.2006070767
25. Shui H., Huang T., Ka S., Chen P., Lin Y., Chen A., Urinary proteome and potential biomarkers associated with serial pathogenesis steps of focal segmental glomerulosclerosis. Nephrology Dialysis Transplantation 2008 23 1 176 185 2-s2.0-43549099362 10.1093/ndt/gfm587
26. Kalantari S., Rutishauser D., Samavat S., Nafar M., Mahmudieh L., Rezaei-Tavirani M., Urinary prognostic biomarkers and classification of IgA nephropathy by high resolution mass spectrometry coupled with liquid chromatography. Plos ONE 2013 8 12 e80830 10.1371/journal.pone. 0080830
27. Lyutvinskiy Y., Yang H., Rutishauser D., Zubarev R. A., In silico instrumental response correction improves precision of label-free proteomics and accuracy of proteomics-based predictive models. Molecular & Cellular Proteomics 2013 12 2324 2233 10.1074/mcp.O112.023804
28. Geladi P., Esbensen K., Regression on multivariate images principal component regression for modeling, prediction and visual diagnostic-tools. Journal of Chemometrics 1991 5 2 97 111 10.1002/cem.1180050206
29. Stella C., Beckwith-Hall B., Cloarec O., Holmes E., Lindon J. C., Powell J., Van Der Ouderaa F., Bingham S., Cross A. J., Nicholson J. K., Susceptibility of human metabolic phenotypes to dietary modulation. Journal of Proteome Research 2006 5 10 2780 2788 2-s2.0-33750213694 10.1021/pr060265y
30. Trygg J., Wold S., Orthogonal projections to latent structures (O-PLS). Journal of Chemometrics 2002 16 3 119 128 2-s2.0-0036083139 10.1002/cem.695
31. Broadhurst D. I., Kell D. B., Statistical strategies for avoiding false discoveries in metabolomics and related experiments. Metabolomics 2006 2 4 171 196 2-s2.0-33846240326 10.1007/s11306-006-0037-z
32. Dennis G. Jr., Sherman B. T., Hosack D. A., Yang J., Gao W., Lane H. C., Lempicki R. A., DAVID: database for annotation, visualization, and integrated discovery. Genome Biology 2003 4 5 P3 2-s2.0-0038005018
33. Thomas D. B., Focal segmental glomerulosclerosis a morphologic diagnosis in evolution. Archives of Pathology and Laboratory Medicine 2009 133 2 217 223 2-s2.0-59949101580
34. Meri S., Lehto T., Sutton C. W., Tyynelä J., Baumann M., Structural composition and functional characterization of soluble CD59: heterogeneity of the oligosaccharide and glycophosphoinositol (GPI) anchor revealed by laser-desorption mass spectrometric analysis. Biochemical Journal 1996 316 3 923 935 2-s2.0-0029760253
35. Meri S., Morgan B. P., Davies A., Daniels R. H., Olavesen M. G., Waldmann H., Lachmann P. J., Human protectin (CD59), an 18,000-20,000 MW complement lysis restricting factor, inhibits C5b-8 catalysed insertion of C9 into lipid bilayers. Immunology 1990 71 1 1 9 2-s2.0-0025179976
36. Rollins S. A., Sims P. J., The complement-inhibitory activity of CD59 resides in its capacity to block incorporation of C9 into membrane C5b-9. Journal of Immunology 1990 144 9 3478 3483 2-s2.0-0025233715
37. Turnberg D., Lewis M., Moss J., Xu Y., Botto M., Cook H. T., Complement activation contributes to both glomerular and tubulointerstitial damage in adriamycin nephropathy in mice. Journal of Immunology 2006 177 6 4094 4102 2-s2.0-33748513032
38. Arora M., Arora R., Das N., Srivastava L. M., Expression of complement regulatory proteins in idiopathic focal segmental glomerulosclerosis. Immunopharmacology 2000 49 1-2 28
39. Sariolu S., Sis B., Tuncer C., Çelik A., Zeybel M., Soylu A., Gülay H., Tubular CD44 expression in renal allograft biopsies. Transplantation Proceedings 2004 36 1 92 94 2-s2.0-0842303346 10.1016/j.transproceed.2003.11.010
40. Zhang J., Pippin J. W., Krofft R. D., Naito S., Liu Z. H., Shankland S. J., Podocyte repopulation by renal progenitor cells following glucocorticoids treatment in experimental FSGS. American Journal of Physiology-Renal Physiology 2013 304 F1375 F1389 10.1152/ajprenal.00020.2013
41. Fatima H., Moeller M. J., Smeets B., Yang H. C., D'Agati V. D., Alpers C. E., Fogo A. B., Parietal epithelial cell activation marker in early recurrence of FSGS in the transplant. Clinical Journal of the American Society of Nephrology 2012 7 11 1852 1858
42. Nakamura H., Kitazawa K., Honda H., Sugisaki T., Roles of and correlation between α -smooth muscle actin, CD44, hyaluronic acid and osteopontin in crescent formation in human glomerulonephritis. Clinical Nephrology 2005 64 6 401 411 2-s2.0-29244459703
43. Matsumoto T., Hess S., Kajiyama H., Sakairi T., Saleem M. A., Mathieson P. W., Nojima Y., Kopp J. B., Proteomic analysis identifies insulin-like growth factor-binding protein-related protein-1 as a podocyte product. American Journal of Physiology-Renal Physiology 2010 299 4 F776 F784 2-s2.0-77957981927 10.1152/ajprenal.00597.2009
44. Burger A. M., Zhang X., Li H., Ostrowski J. L., Beatty B., Venanzoni M., Papas T., Seth A., Down-regulation of T1A12/mac25, a novel insulin-like growth factor binding protein related gene, is associated with disease progression in breast carcinomas. Oncogene 1998 16 19 2459 2467 2-s2.0-0032516239
45. Kato M. V., A secreted tumor-suppressor, mac25, with activin-binding activity. Molecular Medicine 2000 6 2 126 135 2-s2.0-0034138267
46. Brunisholz R. A., Hunziker P., Frey F. J., Jörres A., Identification of IGFBP-7 by urinary proteomics as a novel prognostic marker in early acute kidney injury. Kidney International 2013
47. Konvalinka A., Scholey J. W., Diamandis E. P., Searching for new biomarkers of renal diseases through proteomics. Clinical Chemistry 2012 58 2 353 365 2-s2.0-84856400021 10.1373/clinchem.2011.165969
48. Good D. M., Zürbig P., Argilés A., Naturally occurring human urinary peptides for use in diagnosis of chronic kidney disease. Molecular & Cellular Proteomics 2010 9 11 2424 2437
49. Chen X., Wen Z., Xu W., Xiong S., Granulin exacerbates lupus nephritis via enhancing macrophage M2b polarization. PLoS ONE 2013 8 6 e65542
50. Nielsen R., Mollet G., Esquivel E. L., Weyer K., Nielsen, Antignac C., Christensen E. I., Increased lysosomal proteolysis counteracts protein accumulation in the proximal tubule during focal segmental glomerulosclerosis. Kidney International 2013 84 902 910 10.1038/ki.2013.218
51. Prinsen B. H., de Sain-van der Velden M. G., Kaysen G. A., Straver H. W. H. C., Van Rijn H. J. M., Stellaard F., Berger R., Rabelink T. J., Transferrin synthesis is increased in nephrotic patients insufficiently to replace urinary losses. Journal of the American Society of Nephrology 2001 12 5 1017 1025 2-s2.0-0035035576
52. Kaysen G. A., Plasma composition in the nephrotic syndrome. American Journal of Nephrology 1993 13 5 347 359 2-s2.0-0027744281
53. Li Y., Wang J., Zhu X., Feng Q., Li X., Feng X., Urinary protein markers predict the severity of renal histological lesions in children with proliferative glomerulonephritis. BMC Nephrology 2012 20 13 29
54. Candiano G., Musante L., Bruschi M., Petretto A., Santucci L., Del Boccio P., Pavone B., Perfumo F., Urbani A., Scolari F., Ghiggeri G. M., Repetitive fragmentation products of albumin and α 1-antitrypsin in glomerular diseases associated with nephrotic syndrome. Journal of the American Society of Nephrology 2006 17 11 3139 3148 2-s2.0-33750718487 10.1681/ASN.2006050486
55. Kaysen G. A., De Sain-Van Der Velden M. G. M., New insights into lipid metabolism in the nephrotic syndrome. Kidney International 1999 56 supplement 71 S-18 S-21 2-s2.0-0032974220
56. Barter P. J., Rye K.-A., The rationale for using apoA-I as a clinical marker of cardiovascular risk. Journal of Internal Medicine 2006 259 5 447 454 2-s2.0-33646005529 10.1111/j.1365-2796.2006.01647.x
57. Lopez-Hellin J., Cantarell C., Jimeno L., Sanchez-Fructuoso A., Puig-Gay N., Guirado L., A form of apolipoprotein a-I is found specifically in relapses of focal segmental glomerulosclerosis following transplantation. American Journal of Transplantation 2013 13 2 493 500 10.1111/j.1600-6143.2012.04338.x
58. Ligresti G., Aplin A. C., Dunn B. E., Morishita A., Nicosia R. F., The acute phase reactant orosomucoid-1 Is a bimodal regulator of angiogenesis with time- and context-dependent inhibitory and stimulatory properties. PLoS ONE 2012 7 8 e41387
59. Hochepied T., Berger F. G., Baumann H., Libert C., α 1-acid glycoprotein: an acute phase protein with inflammatory and immunomodulating properties. Cytokine and Growth Factor Reviews 2003 14 1 25 34 2-s2.0-0037301226 10.1016/S1359-6101(02)00054-0
60. Ceciliani F., Pocacqua V., The acute phase protein α 1-acid glycoprotein: a model for altered glycosylation during diseases. Current Protein and Peptide Science 2007 8 1 91 108 2-s2.0-33847315056 10.2174/ 138920307779941497
61. Christiansen M. S., Iversen K., Larsen C. T., Goetze J. P., Hommel E., Mølvig J., Pedersen B. K., Magid E., Feldt-Rasmussen B., Increased urinary orosomucoid excretion: a proposed marker for inflammation and endothelial dysfunction in patients with type 2 diabetes. Scandinavian Journal of Clinical and Laboratory Investigation 2009 69 2 272 281 2-s2.0-65649108650 10.1080/00365510802531100
62. Sharma M., Halligan B. D., Wakim B. T., Savin V. J., Cohen E. R., Moulder J. E., The urine proteome as a biomarker of radiation injury. Proteomics-Clinical Applications 2008 2 7-8 1065 1086 2-s2.0-50849095208 10.1002/prca.200780153
63. Scandrett A. L., Kissane J., Lefkowith J. B., Acute inflammation is the harbinger of glomerulosclerosis in anti- glomerular basement membrane nephritis. American Journal of Physiology-Renal Fluid and Electrolyte Physiology 1995 268 2, part 2 F258 F265 2-s2.0-0029158783
64. Dickinson R. E., Duncan W. C., The SLIT-ROBO pathway: a regulator of cell function with implications for the reproductive system. Reproduction 2010 139 4 697 704 2-s2.0-77949793763 10.1530/REP-10-0017
65. Ronca F., Andersen J. S., Paech V., Margolis R. U., Characterization of slit protein interactions with glypican-1. Journal of Biological Chemistry 2001 276 31 29141 29147 2-s2.0-0035800761 10.1074/jbc.M100240200
66. Sheldon H., Andre M., Legg J. A., Heal P., Herbert J. M., Sainson R., Sharma A. S., Kitajewski J. K., Heath V. L., Bicknell R., Active involvement of Robol and Robo4 in filopodia formation and endothelial cell motility mediated via WASP and other actin nucleation-promoting factors. FASEB Journal 2009 23 2 513 522 2-s2.0-59649086084 10.1096/fj.07-098269
67. Mundel P., Reiser J., Proteinuria: an enzymatic disease of the podocyte. Kidney International 2010 77 7 571 580 2-s2.0-77949541746 10.1038/ki.2009.424
68. Ransom R. F., Lam N. G., Hallett M. A., Atkinson S. J., Smoyer W. E., Glucocorticoids protect and enhance recovery of cultured murine podocytes via actin filament stabilization. Kidney International 2005 68 6 2473 2483 2-s2.0-32844469380 10.1111/j.1523-1755.2005.00723.x
69. Habib G. M., Barriost R., Shi Z., Lieberman M. W., Four distinct membrane-bound dipeptidase RNAs are differentially expressed and show discordant regulation with γ -glutamyl transpeptidase. Journal of Biological Chemistry 1996 271 27 16273 16280 2-s2.0-0030056115 10.1074/jbc.271.27.16273
70. Kozak E. M., Tate S. S., Glutathione-degrading enzymes of microvillus membranes. Journal of Biological Chemistry 1982 257 11 6322 6327 2-s2.0-0019988899
71. Curthoys N. P., Vina J., Renal handling of glutathione. Glutathione: Metabolism and Physiological Functions 1990 Boca Raton, Fla, USA CRC Press 217 226
72. Winn M. P., Daskalakis N., Spurney R. F., Middleton J. P., Unexpected role of TRPC6 channel in familial nephrotic syndrome: does it have clinical implications? Journal of the American Society of Nephrology 2006 17 2 378 387 2-s2.0-33645461305 10.1681/ASN.2005090962
73. Teschner M., Paczek L., Schaefer R. M., Heidland A., Obese Zucker rat: potential role of intraglomerular proteolytic enzymes in the development of glomerulosclerosis. Research in Experimental Medicine 1991 191 2 129 135 2-s2.0-0025811214