Proinflammatory role of angiotensin II in a rat nephrosis model induced by adriamycin

JRAAS - Journal of the Renin-Angiotensin-Aldosterone System

Volumn 12, Issue 4, 2011, Pages 404-412

  Muñoz, Maydelin ^a   Rincón, Jaimar ^a   Pedreañez, Adriana ^b   Viera, Ninoska ^a   Hernández Fonseca, Juan P ^a   Mosquera, Jesús ^a  

^a UNIVERSIDAD DEL ZULIA   (Venezuela)

^b UNIVERSIDAD DEL ZULIA   (Venezuela)

Author keywords

Adriamycin; angiotensin II; inflammation; losartan; nephrotic syndrome

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; DOXORUBICIN; INTERCELLULAR ADHESION MOLECULE 1; LOSARTAN; LOSARTAN POTASSIUM; SUPEROXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; HISTOCHEMISTRY; IMMUNOFLUORESCENCE; MACROPHAGE; MALE; NEPHROSIS; NONHUMAN; PROTEIN EXPRESSION; PROTEINURIA; RAT;

ANGIOTENSIN II; ANIMALS; CHOLESTEROL; DISEASE MODELS, ANIMAL; DOXORUBICIN; ENDOTHELIN-1; FLUORESCENT ANTIBODY TECHNIQUE; INFLAMMATION; INFLAMMATION MEDIATORS; KIDNEY; LOSARTAN; MALE; NEPHROSIS; PROTEINURIA; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS; TRIGLYCERIDES; WEIGHT GAIN;

EID: 83455219479     PISSN: 14703203     EISSN: 17528976     Source Type: Journal    
DOI: 10.1177/1470320311410092     Document Type: Article

References (51)

1. Ruiz-Ortega M, Ruperez M, Lorenzo O, et al. Angiotensin II regulates the synthesis of proinflammatory cytokines and chemokines in the kidney. Kidney Int. 2002 ; 82: S12 - S22
2. Wolf G, Neilson EG. Angiotensin II as a renal growth factor. J Am Soc Nephrol. 1993 ; 3: 1531-1540
3. Sadoshima J. Cytokine actions of angiotensin II. Cir Res. 2000 ; 86: 1187-1189 (Pubitemid 30436655)
4. Ruiz-Ortega M, Lorenzo O, Ruperez M, Blanco J, Egido J. Systemic infusion of angiotensin II into normal rats activates nuclear factor-kB and AP-1 in the kidney: role of AT(1) and AT(2) receptors. Am J Pathol. 2001 ; 158: 1743-1756 (Pubitemid 32422939)
5. Ruiz-Ortega M, Bustos C, Hernández-Pressa MA, Lorenzo O, Plaza JJ, Egido J. Angiotensin II participates in mononuclear cell recruitment in experimental immune complex nephritis through nuclear factor-kappa B activation and monocyte chemoattractant protein-1 synthesis. J Immunol. 1998 ; 161: 430-439 (Pubitemid 28285552)
6. Piqueras L, Kubes P, Alvarez A, et al. Angiotensin II induces leukocyte-endothelial cell interactions in vivo via AT(1) and AT(2) receptor-mediated P-selectin upregulation. Circulation. 2000 ; 102: 2118-2123
7. Timmermans PB, Wong PC, Chiu AT, et al. Angiotensin II receptors and angiotensin II receptor antagonist. Pharmacol Rev. 1993 ; 45: 205-251
8. Chung O, Kuhl H, Stoll M, Unger T. Physiological and pharmacological implications of AT1 versus AT2 receptors. Kidney Int. 1998 ; 67: S95 - S99
9. Ruiz-Ortega M, Rupérez M, Esteban V, et al. Modulationof angiotensin II effects a potential novel approach to inflammatory and immune diseases. Curr Med Chem. 2003 ; 2: 379-394
10. Wolf G, Ziyadeh FN, Thaiss F, et al. Angiotensin II stimulates expression of the chemokine RANTES in rat glomerular endothelial cells. Role of the angiotensin type 2 receptor. J Clin Invest. 1997 ; 100: 1047-1058 (Pubitemid 27386288)
11. Lo M, Liu KL, Lantelme P, Sassard J. Subtype 2 of angiotensin II receptors controls pressure-natriuresis in rats. J Clin Invest. 1995 ; 95: 1394-1397
12. Matsubara H. Pathophysiological role of angiotensin II type 2 receptor in cardiovascular and renal diseases. Circ Res. 1998 ; 83: 1182-1191 (Pubitemid 29006033)
13. Zoja C, Corna D, Camozzi D, et al. How to fully protect the kidney in a severe model of progressive nephropathy: a multidrug approach. J Am Soc Nephrol. 2002 ; 13: 2898-2908 (Pubitemid 35386909)
14. Lafayette RA, Mayer G, Park SK, Meyer TW. Angiotensin II receptor blockade limits glomerular injury in rats with reduced renal mass. J Clin Invest. 1992 ; 90: 766-771
15. Pollok DM, Divish BJ, Polakowski JS, Opgenorth TJ. Angiotensin II receptor blockade improves renal function in rats with reduced mass. J Pharmacol Exp Ther. 1993 ; 274: 1222-1227
16. Ots M, Mackenzie HS, Troy JL, Brenner BM. Effects of combination therapy with enalapril and losartan on the rate of progression of renal injury in rats with 5/6 renal mass ablation. J Am Soc Nephrol. 1998 ; 9: 224-230 (Pubitemid 28092070)
17. Bertani T, Poggi A, Pozzoni R, et al. Adriamycin-induced nephrotic syndrome in rats: sequence of pathologic events. Lab Invest. 1982 ; 46: 16-23 (Pubitemid 12167012)
18. Bertani T, Cutillo F, Zoja C, Broggini M, Remuzzi G. Tubulo-interstitial lesions mediate renal damage in adriamycin glomerulopathy. Kidney Int. 1986 ; 30: 488-496 (Pubitemid 16000793)
19. Tang SCW, Leung JCK, Chan LYY, Eddy AA, Lai KN. Angiotensin-converting enzyme inhibitor but not angiotensin receptor blockade or statin ameliorates murine adriamycin nephropathy. Kidney Int. 2008 ; 73: 288-299
20. Kim HJ, Ryu JH, Han SW, et al. Combined therapy of cilazapril and losartan has no additive effects in ameliorating adriamycin-induced glomerulopathy. Nephron Physiol. 2004 ; 97: 58-65
21. Mihailovic-Stanojevic N, Jovovic D, Miloradovic Z, Grujic-Milanovic J, Jerkic M, Markovic-Lipkovski J. Reduced progression of adriamycin nephropathy in spontaneously hypertensive rats treated by losartan. Nephrol Dial Transplant. 2009 ; 24: 1142-1150
22. Otaki Y, Miyauchi N, Higa M, et al. Dissociation of NEPH1 from nephrin is involved in development of a rat model of focal segmental glomerulosclerosis. Am J Physiol Renal Physiol. 2008 ; 295: F1376 - F1387
23. Kauffman RF, Bean JS, Zimmerman KM, Brown RF, Steinberg MI. Losartan, a nonpeptide angiotensin II (Ang II) receptor antagonists, inhibits neointima formation following balloon injury to rat carotid arteries. Life Sci. 1991 ; 49: 223-228
24. Briggs RT, Robinson JM, Karnovsky MJ. Superoxide production by polymorphonuclear leukocytes. A cytochemical approach. Histochemistry. 1986 ; 84: 371-378
25. Banes-Berceli AK, Shaw S, Ma G, et al. Effect of simvastatin on high glucose- and angiotensin II-induced activation of the JAK/STAT pathway in mesangial cells. Am J Physiol Renal Physiol. 2006 ; 291: F116 - F121
26. Amiri F, Shaw S, Wang X, et al. Angiotensin II activation of the JAK/STAT pathway in mesangial cells is altered by high glucose. Kidney Int. 2002 ; 61: 1605-1616 (Pubitemid 34437914)
27. Gomez-Garre D, Ruiz-Ortega M, Ortego M, et al. Effects and interactions of endothelin-1 and angiotensin II on matrix protein expression and synthesis and mesangial cell growth. Hypertension. 1996 ; 27: 885-892 (Pubitemid 26113835)
28. Wolf G, Schneider A, Helmchen U, Stahl RAK. AT-receptor antagonists abolish glomerular MCP-1 expression in a model of mesangial proliferative glomerulonephritis. Exp Nephrol. 1998 ; 6: 112-120 (Pubitemid 28140992)
29. Lee FT, Cao Z, Long DM, et al. Interactions between angiotensin II and NF-kB-dependent pathways in modulating macrophage infiltration in experimental diabetic nephropathy. J Am Soc Nephrol. 2004 ; 15: 2139-2151 (Pubitemid 39031352)
30. Wang Y, Wang Y, Cao Q, et al. By homing to the kidney, activated macrophages potently exacerbate renal injury. Am J Pathol. 2008 ; 172: 1491-1499 (Pubitemid 351793343)
31. Pastore L, Tessitore A, Martinotti S, et al. Angiotensin II stimulates intercellular adhesion molecule-1 (ICAM-1) expression by human vascular endothelial cells and increases soluble ICAM-1 release in vivo. Circulation. 1999 ; 100: 1646-1652 (Pubitemid 29477275)
32. Rangan GK, Wang Y, Tay YC, Harris DC. Inhibition of nuclear factor-kappa B activation reduces cortical tubulointerstitial injury in proteinuric rats. Kidney Int. 1999 ; 56: 118-134 (Pubitemid 29300527)
33. Pan Q, Yang XH, Cheng YX. Angiotensin II stimulates MCP-1 production in rat glomerular endothelial cells via NAD(P)H oxidase-dependent nuclear factor-kappa B signaling. Brazilian J Med Biol Res. 2009 ; 42: 531-536
34. Guo YJ, Li WH, Wu R, Xie Q, Cui LQ. ACE2 overexpression inhibits angiotensin II-induced monocyte chemoattractant protein-1 expression in macrophages. Arch Med Res. 2008 ; 39: 149-154 (Pubitemid 350299617)
35. Suzuki H, Shibata H, Murakami M, et al. Modulation of angiotensin II type 1 receptor mRNA expression in human blood cells: comparison of platelets and mononuclear leucocytes. Endocrinol J. 1995 ; 42: 15-22
36. Nguyen G, Delarue F, Burcklé C, Bouzhir L, Giller T, Sraer JD. Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin. J Clin Invest. 2002 ; 109: 1417-1427 (Pubitemid 34596167)
37. Lavoie JL, Sigmund CD. Minireview: overview of the renin-angiotensin system-an endocrine and paracrine system. Endocrinology. 2003 ; 144: 2179-2183 (Pubitemid 36629863)
38. Schunkert H, Ingelfinger JR, Hirsch AT, et al. Evidence for tissue-specific activation of renal angiotensinogen mRNA expression in chronic stable experimental heart failure. J Clin Invest. 1992 ; 90: F1523 - F1529
39. Kobori H, Harrison-Bernard LM, Navar LG. Expression of angiotensinogen mRNA and protein in angiotensin II-dependent hypertension. J Am Soc Nephrol. 2001 ; 12: F431 - F439
40. Wang TT, Chen M, Lachance S, Delalandre A, Carrière S, Chan JSD. Isoproterenol and 8-bromocyclic adenosine monophosphate stimulate the expression of the angiotensinogen gene in opossum kidney cells. Kidney Int. 1994 ; 46: F703 - F710
41. Wang TT, Lachance S, Delalandre A, Carrière S, Chan JSD. Alpha-adrenoceptors and angiotensinogen gene expression in opossum kidney cells. Kidney Int. 1995 ; 48: F139 - F145
42. Kato I, Takada Y, Nishimura K, Hiwada K, Kokubu T. Increased urinary excretion of angiotensin converting enzyme in patients with renal diseases. J Clin Chem Clin Biochem. 1982 ; 20: 473-476
43. Mii A, Shimizu A, Masuda Y, et al. Angiotensin II receptor blockade inhibits acute glomerular injuries with the alteration of receptor expression. Lab Invest. 2009 ; 89: 164-177
44. Vaziri ND, Bai Y, Ni Z, Quiroz Y, Pandian R, Rodriguez-Iturbe B. Intra-renal angiotensin II/AT1 receptor, oxidative stress, inflammation, and progressive injury in renal mass reduction. J Pharmacol Exp Ther. 2007 ; 323: 85-93 (Pubitemid 47443257)
45. Friedland J, Silverstein E. Properties of soluble and particulate angiotensin-converting enzymes of rabbit lung, induced macrophage serum. Int J Biochem. 1983 ; 15: 1337-1343 (Pubitemid 14246147)
46. Koitka A, Cooper ME, Thomas MC, Tikellis C. Angiotensin converting enzyme 2 in the kidney. Clin Exp Pharmacol Physiol. 2008 ; 35: 420-425 (Pubitemid 351326772)
47. Sachse A, Wolf G. Angiotensin II-induced reactive oxygen species and the kidney. J Am Soc Nephrol. 2007 ; 18: 2439-2446 (Pubitemid 47378859)
48. Wu SH. Role of oxygen radicals in adriamycin-induced nephrosis. Chin Med J (Engl). 1990 ; 103: 283-289
49. Griendling KK, Ushio-Fukai M. Reactive oxygen species as mediators of angiotensin II signaling. Regul Pept. 2000 ; 91: 21-27
50. Lu L, Quinn MT, Sun Y. Oxidative stress in the infarcted heart: role of de novo angiotensin II production. Biochem Biophys Res Commun. 2004 ; 325: 943-951 (Pubitemid 39487963)
51. Lassègue B, Clempus RE. Vascular NAD(P)H oxidases: specific features, expression, and regulation. Am J Physiol Regul Integr Comp Physiol. 2003 ; 285: R277 - R297