The urine proteome as a biomarker of radiation injury

Proteomics - Clinical Applications

Volumn 2, Issue 7-8, 2008, Pages 1065-1086

  Sharma, Mukut ^a,b   Halligan, Brian D ^a   Wakim, Bassam T ^a   Savin, Virginia J ^a   Cohen, Eric R ^a   Moulder, John E ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b Nephrology/CVC/MEB   (United States)

Author keywords

Biomarkers; Nuclear accidents; Radiation injury; Radiological terrorism; Urine proteome

Indexed keywords

BIOLOGICAL MARKER; CYSTATIN C; CYSTEINE PROTEINASE INHIBITOR; HISTIDINE; OXIDIZED HISTIDINE; PEPTIDASE; SERUM ALBUMIN; TISSUE KALLIKREIN; TISSUE KALLIKREIN 1 RELATED PEPTIDASE;

ALBUMIN BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE MARKER; GLOMERULAR DYSFUNCTION; GLOMERULUS FILTRATION; KALLIKREIN URINE LEVEL; KIDNEY FUNCTION; KIDNEY INJURY; LIQUID CHROMATOGRAPHY; MACROMOLECULE; MASS SPECTROMETRY; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATION; PODOCYTE; PRIORITY JOURNAL; PROTEIN MODIFICATION; PROTEIN OXIDATION; PROTEIN URINE LEVEL; RADIATION INJURY; RAT; TWO DIMENSIONAL ELECTROPHORESIS; ULTRASTRUCTURE; UNINDEXED SEQUENCE; URINALYSIS; WHOLE BODY RADIATION;

RATTUS;

EID: 50849095208     PISSN: 18628346     EISSN: None     Source Type: Journal    
DOI: 10.1002/prca.200780153     Document Type: Article

References (41)

1. Cohen, E. P., Renal failure after bone-marrow transplantation. Lancet 2001, 357, 6-7.
2. Lambert, B., Cybulla, M., Weiner, S. M., Van De Wiele, C. et al., Renal toxicity after radionuclide therapy. Radiat. Res. 2004, 161, 607-611.
3. Cohen, E., in: Davison, A. M., Cameron, J., Grünfeld, J., Ponticelli, C. (Eds.), Oxford Textbook of Clinical Nephrology, Oxford University Press, Oxford, New York 2005, pp. 1091-1094.
4. Moulder, J. E., Report on an interagency workshop on the radiobiology of nuclear terrorism. Molecular and cellular biology dose (1-10 Sv) radiation and potential mechanisms of radiation protection (Bethesda, Maryland, December 17-18, 2001). Radiat. Res. 2002, 158, 118-124.
5. Pellmar, T. C., Rockwell, S., Priority list of research areas for radiological nuclear threat countermeasures. Radiat. Res. 2005, 163, 115-123.
6. Ricks, R. C., Berger, M. E., O'Hara, F. M., The Medical Basis for Radiation-Accident Preparedness: The Clinical Care of Victims, Proceedings of the Fourth International REAC/TS Conference on the Medical Basis for Radiation-Accident Preparedness, held March 6-8, 2001, in Orlando, Florida, Parthenon Pub. Group, Boca Raton 2002.
7. Jarrett, D. G., Medical Management of Radiological Casualties, Armed Forces Radiobiology Research Institute, Bethesda, MD 1999.
8. Rose, C. M., Radiation scientists and homeland security. Radiat. Res. 2002, 157, 607-609.
9. Manthous, C. A., Jackson, W. L., Jr., The 9-11 Commission's invitation to imagine: A pathophysiology-based approach to critical care of nuclear explosion victims. Crit. Care Med. 2007, 35, 716-723.
10. Cohen, E. P., Fish, B. L., Moulder, J. E., The renin-angiotensin system in experimental radiation nephropathy. J. Lab. Clin. Med. 2002, 139, 251-257.
11. Moulder, J. E., Fish, B. L., Late toxicity of total body irradiation with bone marrow transplantation in a rat model. Int. J. Radiat. Oncol. Biol. Phys. 1989, 16, 1501-1509.
12. Sharma, M., Sharma, R., Ge, X. L., Fish, B. L. et al., Early detection of radiation-induced glomerular injury by albumin permeability assay. Radiat. Res. 2001, 155, 474-480.
13. Fliser, D., Novak, J., Thongboonkerd, V., Argiles, A. et al., Advances in urinary proteome analysis and biomarker discovery. J. Am. Soc. Nephrol. 2007, 18, 1057-1071.
14. Cohen, E. P., Moulder, J. E., Fish, B. L., Hill, P., Prophylaxis of experimental bone marrow transplant nephropathy. J. Lab. Clin. Med. 1994, 124, 371-380.
15. Savin, V. J., Sharma, R., Lovell, H. B., Welling, D. J., Measurement of albumin reflection coefficient with isolated rat glomeruli. J. Am. Soc. Nephrol. 1992, 3, 1260-1269.
16. Sharma, M., Sharma, R., McCarthy, E. T., Savin, V. J., "The FSGS factor: Enrichment and in vivo effect of activity from focal segmental glomerulosclerosis plasma. J. Am. Soc. Nephrol. 1999, 10, 552-561.
17. Bantscheff, M., Schirle, M., Sweetman, G., Rick, J., Kuster, B., Quantitative mass spectrometry in proteomics: A critical review. Analy. Bioanal. Chem. 2007, 389, 1017-1031.
18. Old, W. M., Meyer-Arendt, K., Aveline-Wolf, L, Pierce, K. G. et al., Comparison of label-free methods for quantifying human proteins by shotgun proteomics. Mol. Cell. Proteomics 2005, 4, 1487-1502.
19. Ashburner, M., Ball, C. A., Blake, J. A., Botstein, D. et al., Gene ontology: Tool for the unification of biology. The Gene Ontology Consortium. Nat. Genet. 2000, 25, 25-29.
20. Bonventre, J. V., Diagnosis of acute kidney injury: From classic parameters to new biomarkers. Contrib. Nephrol. 2007, 156, 213-219.
21. Honore, P. M., Joannes-Boyau, O., Boer, W., The early biomarker of acute kidney injury: In search of the Holy Grail. Intens. Care Med. 2007, 33, 1866-1868.
22. Savin, V. J., McCarthy, E. T., Sharma, M., Permeability factors in focal segmental glomerulosclerosis. Semin. Nephrol. 2003, 23, 147-160.
23. Sharma, M., McCarthy, E. T., Sharma, R., Fish, B. L. et al., Arachidonic acid metabolites mediate the radiation-induced increase in glomerular albumin permeability. Exp. Biol. Med. 2006, 231, 99-106.
24. Datta, P. K., Moulder, J. E., Fish, B. L., Cohen, E. P. et al., TGF-b1 production in radiation nephropathy: Role of angiotensin II. Int. J. Radiat. Biol. 1999, 75, 473-479.
25. Hoorn, E. J., Pisitkun, T., Zietse, R., Gross, P. et al., Prospects for urinary proteomics: Exosomes as a source of urinary biomarkers. Nephrologyc 2005, 10, 283-290.
26. Veenstra, T. D., Conrads, T. P., Hood, B. L., Avellino, A. M. et al., Biomarkers: Mining the biofluid proteome. Mol. Cell. Proteomics 2005, 4, 409-418.
27. Thongboonkerd, V., Klein, J., Jevans, A., McLeish, K., in: Ronco, C. (Ed.), Contributions in Nephrology, Karger AG, Basel, Switzerland 2004, pp. 292-307.
28. Horvath, A. J., Forsyth, S. L., Coughlin, P. B., Expression patterns of murine antichymotrypsin-like genes reflect evolutionary divergence at the Serpina3 locus. J. Mol. Evol. 2004, 59, 488-497.
29. Suzuki, Y., Yoshida, K., Honda, E., Sinohara, H., Molecular cloning and sequence analysis of cDNAs coding far guinea pig alpha 1-antiproteinases S and F and contrapsin. J. Biol. Chem. 1991, 266, 928-932.
30. Sharma, M., Sharma, R., McCarthy, E. T., Savin, V. J., The focal segmental glomerulosclerosis permeability factor: Biochemical characteristics and biological effects. Exp. Biol. Med. 2004, 229, 85-98.
31. Sharma, M., McCarthy, E. T., Savin, V. J., Lianos, E. A., Nitric oxide preserves the glomerular protein permeability barrier by antagonizing superoxide. Kidney Int. 2005, 68, 2735-2744.
32. Burkle, A., Poly(APD-ribosyl)ation, a DNA damage-driven protein modification and regulator of genomic instability. Cancer Lett. 2001, 163, 1-5.
33. Lakin, N. D., Jackson, S. P., Regulation of p53 in response to DNA damage. Oncogene 1999, 18, 7644-7655.
34. Robbins, M. E., Bonsib, S. M., Radiation nephropathy: A review. Scan. Microsc. 1995, 9, 535-560.
35. Kriengsinyos, W., Rafii, M., Wykes, L. J., Ball, R. O., Pencharz, P. B., Long-term effects of histidine depletion on whole-body protein metabolism in healthy adults. J. Nutr. 2002, 132, 3340-3348.
36. Uchida, K., Kawakishi, S., 2-Oxo-histidine as a novel biological marker for oxidatively modified proteins. FEBS Lett. 1993, 332, 208-210.
37. Uchida, K., Stadtman, E. R., Modification of histidine residues in proteins by reaction with 4-hydroxynonenal. Proc. Natl. Acad. Sci. USA 1992, 89, 4544-4548.
38. Yammani, R. R., Sharma, M., Seetharam, S., Moulder, J. E. et al., Loss of albumin and megalin binding to renal cubilin in rats results in albuminuria after total body irradiation. Am. J. Physiol. 2002, 283, R339-R346.
39. alb assay confirm that increased glomerular protein permeability precedes proteinuria in puromycin aminonucleoside (PAN) nephrosis. J. Am. Soc. Nephrol. 2004, 15, 490A.
40. Kalousava, M., Zima, T., Tesar, V., Dusilova-Sulkova, S., Skrha, J., Advanced glycoxidation end products in chronic diseases-clinical chemistry and genetic background. Mutat. Res. 2005, 579, 37-46.
41. Narita, T., Sasaki, H., Hosoba, M., Miura, T. et al., Parallel increase in urinary excretion rates of Ig G, ceruloplasmin, transferrin, and orosomucoid in normoalbuminuric type 2 diabetic patients. Diabetes Care 2004, 27, 1176-1181.