Transferrin synthesis is increased in nephrotic patients insufficiently to replace urinary losses

Journal of the American Society of Nephrology

Volumn 12, Issue 5, 2001, Pages 1017-1025

  Prinsen, B H C M T ^a   De Sain van der Velden, M G M ^a   Kaysen, G A ^a   Straver, H W H C ^a   Van Rijn, H J M ^a   Stellaard, F ^a   Berger, R ^a   Rabelink, T J ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; CARBON 13; IRON; TRANSFERRIN; VALINE;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION FUNCTION; FEMALE; HUMAN; INFLAMMATION; IRON BLOOD LEVEL; IRON DEFICIENCY; MALE; MICROCYTIC ANEMIA; NEPHROTIC SYNDROME; PRIORITY JOURNAL; PROTEIN SYNTHESIS; PROTEIN URINE LEVEL; PROTEINURIA; TRANSFERRIN BLOOD LEVEL;

EID: 0035035576     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Plasma composition in the nephrotic syndrome
2. Decreased serum transferrin concentration in children with the nephrotic syndrome: Effect on lymphocyte proliferation and correlation with serum immunoglobulin levels
3. Iron homeostasis in relapsing steroid-sensitive nephrotic syndrome of childhood
4. The synthesis and secretion of rat transferrin
5. Cell type-specific expression of the human transferrin gene. Role of promoter, negative, and enhancer elements
6. Rat transferrin gene expression: Tissue-specific regulation by iron deficiency
7. Transferrin gene expression in choroid plexus of the adult rat brain
8. Iron metabolism and its regulation. A review
9. Iron and the liver
10. Function and regulation of transferrin and ferritin
11. Disorders of iron metabolism
12. Reference distributions for the negative acute-phase serum proteins, albumin, transferrin and transthyretin: A practical, simple and clinically relevant approach in a large cohort
13. Proteins
14. Congenital atransferrinemia. A case report and review of the literature
15. Urinary excretion of iron-binding protein in the nephrotic syndrome
16. Transferrin loss into the urine with hypochromic, microcytic anemia
17. Treatment of anemia of nephrotic syndrome with recombinant erythropoietin
18. Erythropoietin metabolism and pharmacokinetics in experimental nephrosis
19. Inflammation triggers hypoferremia and de novo synthesis of serum transferrin and ceruloplasmin in mice
20. Transferrin kinetics are altered in children with severe protein-energy malnutrition
21. Chronic protein deficiency differentially affects the kinetics of plasma proteins in young pigs
22. Non-iron mediated alteration in hepatic transferrin gene expression in the nephrotic rat
23. Transferrin metabolism in the nephrotic syndrome and in protein-losing gastroenteropathy
24. Physico-chemical factors of drugs affecting absorption, distribution, and excretion
25. Isolation of rat transferrin using CNBr-activated sepharose 4B
26. Hydrolysis of proteins
27. Rapid derivatization and gas chromagraphic determination of amino acids
28. Solubility of albumin in alcohol after precipitation by trichloric acid: A simplified procedure for separation of albumin
29. Quantitation of 2-ketoacids in biological fluids by gas chromatography chemical ionization mass spectrometry of O-trimethylsilyl-quinoxalinol derivatives
30. Determination of low isotopic enrichment of L-[1-13C]valine by gas chromatography/combustion/isotope ratio mass spectrometry: A robust method for measuring protein fractional synthetic rates in vivo
31. Proportionate increase of fibrinogen and albumin synthesis in nephrotic patients: Measurements with stable isotopes
32. Urinary albumin, transferrin and iron excretion in diabetic patients
33. Iron and protein kinetics studied by means of doubly labeled human crystalline transferrin
34. The acute effect of ethanol on albumin, fibrinogen and transferrin synthesis in the rat
35. The effect of cortisol on the synthesis of rat plasma albumin, fibrinogen and transferrin
36. Kinetics and characteristics of an acute phase response following cardiac arrest
37. Total body protein synthesis does not increase despite increased synthesis and urinary losses of liver derived protein in the nephrotic syndrome
38. Mechanisms permitting nephrotic patients to achieve nitrogen equilibrium with a protein-restricted diet
39. Albumin and transferrin synthesis are increased in H4 cells by serum from analbuminemic or nephrotic rats
40. Role of iron and oxygen radicals in the progression of chronic renal failure
41. Urinary iron speciation in nephrotic syndrome