The Rho GTPase Rac1 is required for recycling endosome-mediated secretion of TNF in macrophages

Immunology and Cell Biology

Volumn 92, Issue 3, 2014, Pages 275-286

  Stanley, Amanda C ^a   Wong, Colin X ^b   Micaroni, Massimo ^c   Venturato, Juliana ^a   Khromykh, Tatiana ^a   Stow, Jennifer L ^a   Lacy, Paige ^d  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b INSTITUTE OF MEDICAL BIOLOGY   (Singapore)

^c UNIVERSITY OF EXETER   (United Kingdom)

^d UNIVERSITY OF ALBERTA   (Canada)

Author keywords

cytokine; macrophage; Rac1; Rho GTPase; TNF; trafficking

Indexed keywords

GUANOSINE TRIPHOSPHATASE; PROTEIN CDC42; RAC1 PROTEIN; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR;

ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ARTICLE; CELL MEMBRANE; CELLULAR SECRETION; CYTOKINE RELEASE; ENDOSOME; GENE SILENCING; GENETIC TRANSFECTION; INTRACELLULAR SIGNALING; INTRACELLULAR TRANSPORT; MACROPHAGE; MOUSE; MUTANT; NONHUMAN;

MUS;

ANIMALS; CDC42 GTP-BINDING PROTEIN; CELL LINE; CELL MEMBRANE; ENDOCYTOSIS; ENDOSOMES; GENE DELETION; GENE KNOCKDOWN TECHNIQUES; GREEN FLUORESCENT PROTEINS; MACROPHAGES; MICE; MICE, INBRED C57BL; PROTEIN TRANSPORT; PSEUDOPODIA; PYRONES; QUINOLINES; RAC GTP-BINDING PROTEINS; RAC1 GTP-BINDING PROTEIN; RECOMBINANT FUSION PROTEINS; RNA, SMALL INTERFERING; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84899454173     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1038/icb.2013.90     Document Type: Article

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