-
1
-
-
77949875831
-
Novel targeted therapeutics for metastatic castration-resistant prostate cancer
-
doi:10.1016/j.canlet.2009.08.012
-
Antonarakis ES, Carducci MA, Eisenberger MA (2010) Novel targeted therapeutics for metastatic castration-resistant prostate cancer. Cancer Lett 291:1-13. doi:10.1016/j.canlet.2009.08.012
-
(2010)
Cancer Lett
, vol.291
, pp. 1-13
-
-
Antonarakis, E.S.1
Carducci, M.A.2
Eisenberger, M.A.3
-
2
-
-
57449111076
-
mTOR pathway and mTOR inhibitors as agents for cancer therapy
-
Baldo P et al (2008) mTOR pathway and mTOR inhibitors as agents for cancer therapy. Curr Cancer Drug Targets 8:647-665
-
(2008)
Curr Cancer Drug Targets
, vol.8
, pp. 647-665
-
-
Baldo, P.1
-
3
-
-
84855895252
-
Targeting the PI3K signaling pathway in cancer therapy
-
doi:10.1007/s11912-012-0227-y
-
Bartholomeusz C, Gonzalez-Angulo AM (2012) Targeting the PI3K signaling pathway in cancer therapy. Expert Opin Ther Targets 16:121-130. doi:10.1007/s11912-012-0227-y
-
(2012)
Expert Opin Ther Targets
, vol.16
, pp. 121-130
-
-
Bartholomeusz, C.1
Gonzalez-Angulo, A.M.2
-
4
-
-
54949108677
-
PubChem: Integrated platform of small molecules and biological activities
-
Bolton EE et al (2008) PubChem: integrated platform of small molecules and biological activities. Annu Rep Comput Chem 4:217-241
-
(2008)
Annu Rep Comput Chem
, vol.4
, pp. 217-241
-
-
Bolton, E.E.1
-
6
-
-
56449116314
-
Contribution of natural inhibitors to the understanding of the PI3K/PDK1/PKB pathway in the insulin-mediated intracellular signaling cascade
-
doi:10.3390/ijms9112217
-
Cho JY, Park J (2008) Contribution of natural inhibitors to the understanding of the PI3K/PDK1/PKB pathway in the insulin-mediated intracellular signaling cascade. Int J Mol Sci 9:2217-2230. doi:10.3390/ijms9112217
-
(2008)
Int J Mol Sci
, vol.9
, pp. 2217-2230
-
-
Cho, J.Y.1
Park, J.2
-
7
-
-
0035433799
-
Natural products in anticancer therapy
-
DOI 10.1016/S1471-4892(01)00063-7, PII S1471489201000637
-
da Rocha AB, Lopes RM, Schwartsmann G (2001) Natural products in anticancer therapy. Curr Opin Pharmacol 1:364-369 (Pubitemid 33585985)
-
(2001)
Current Opinion in Pharmacology
, vol.1
, Issue.4
, pp. 364-369
-
-
Da, R.A.B.1
Lopes, R.M.2
Schwartsmann, G.3
-
8
-
-
57349143716
-
Targeting RAS and PI3K in lung cancer
-
doi:10.1038/nm1208-1315
-
Downward J (2008) Targeting RAS and PI3K in lung cancer. Nat Med 14:1315-1316. doi:10.1038/nm1208-1315
-
(2008)
Nat Med
, vol.14
, pp. 1315-1316
-
-
Downward, J.1
-
9
-
-
0034677966
-
Drug discovery: A historical perspective
-
Drews Jr (2000) Drug discovery: a historical perspective. Science 287:1960-1964
-
(2000)
Science
, vol.287
, pp. 1960-1964
-
-
Drews, J.1
-
10
-
-
33750072949
-
mTOR and cancer therapy
-
DOI 10.1038/sj.onc.1209886, PII 1209886
-
Easton J, Houghton P (2006) mTOR and cancer therapy. Oncogene 25:6436-6446 (Pubitemid 44582287)
-
(2006)
Oncogene
, vol.25
, Issue.48
, pp. 6436-6446
-
-
Easton, J.B.1
Houghton, P.J.2
-
11
-
-
33746637660
-
Current development of mTOR inhibitors as anticancer agents
-
DOI 10.1038/nrd2062, PII NRD2062
-
Faivre S, Kroemer G, Raymond E (2006) Current development of mTOR inhibitors as anticancer agents. Nat Rev Drug Discov 5:671-688 (Pubitemid 44151605)
-
(2006)
Nature Reviews Drug Discovery
, vol.5
, Issue.8
, pp. 671-688
-
-
Faivre, S.1
Kroemer, G.2
Raymond, E.3
-
12
-
-
77953758752
-
Design of selective, ATP-competitive inhibitors of Akt
-
doi:10.1021/jm1003842
-
Freeman-Cook KD et al (2010) Design of selective, ATP-competitive inhibitors of Akt. J Med Chem 53:4615-4622. doi:10.1021/jm1003842
-
(2010)
J Med Chem
, vol.53
, pp. 4615-4622
-
-
Freeman-Cook, K.D.1
-
13
-
-
12144289984
-
Glide: A New Approach for Rapid, Accurate Docking and Scoring. 1. Method and Assessment of Docking Accuracy
-
DOI 10.1021/jm0306430
-
Friesner RA et al (2004) Glide: a new approach for rapid, accurate docking and scoring. 1. Method and assessment of docking accuracy. J Med Chem 47:1739-1749 (Pubitemid 38380917)
-
(2004)
Journal of Medicinal Chemistry
, vol.47
, Issue.7
, pp. 1739-1749
-
-
Friesner, R.A.1
Banks, J.L.2
Murphy, R.B.3
Halgren, T.A.4
Klicic, J.J.5
Mainz, D.T.6
Repasky, M.P.7
Knoll, E.H.8
Shelley, M.9
Perry, J.K.10
Shaw, D.E.11
Francis, P.12
Shenkin, P.S.13
-
14
-
-
33750124980
-
Extra precision glide: Docking and scoring incorporating a model of hydrophobic enclosure for protein-ligand complexes
-
DOI 10.1021/jm051256o
-
Friesner RA et al (2006) Extra precision glide: docking and scoring incorporating a model of hydrophobic enclosure for protein-ligand complexes. J Med Chem 49:6177-6196 (Pubitemid 44595196)
-
(2006)
Journal of Medicinal Chemistry
, vol.49
, Issue.21
, pp. 6177-6196
-
-
Friesner, R.A.1
Murphy, R.B.2
Repasky, M.P.3
Frye, L.L.4
Greenwood, J.R.5
Halgren, T.A.6
Sanschagrin, P.C.7
Mainz, D.T.8
-
15
-
-
1642310340
-
Glide: A New Approach for Rapid, Accurate Docking and Scoring. 2. Enrichment Factors in Database Screening
-
DOI 10.1021/jm030644s
-
Halgren TA et al (2004) Glide: a new approach for rapid, accurate docking and scoring. 2. Enrichment factors in database screening. J Med Chem 47:1750-1759 (Pubitemid 38380918)
-
(2004)
Journal of Medicinal Chemistry
, vol.47
, Issue.7
, pp. 1750-1759
-
-
Halgren, T.A.1
Murphy, R.B.2
Friesner, R.A.3
Beard, H.S.4
Frye, L.L.5
Pollard, W.T.6
Banks, J.L.7
-
16
-
-
24944480788
-
The Akt-mTOR tango and its relevance to cancer
-
Hay N (2005) The Akt-mTOR tango and its relevance to cancer. Cancer Cell 8:179-183
-
(2005)
Cancer Cell
, vol.8
, pp. 179-183
-
-
Hay, N.1
-
17
-
-
84872127030
-
Dietary agents in cancer chemoprevention and treatment
-
doi:10.1155/2012/749310
-
Hillman GG (2012) Dietary agents in cancer chemoprevention and treatment. J Oncol 2012. doi:10.1155/2012/749310
-
(2012)
J Oncol
, vol.2012
-
-
Hillman, G.G.1
-
18
-
-
84861590032
-
Triptolide inhibits the proliferation of prostate cancer cells and down-regulates SUMO-specific Protease 1 expression
-
doi:10.1371/journal.pone.0037693
-
Huang W et al (2012) Triptolide inhibits the proliferation of prostate cancer cells and down-regulates SUMO-specific Protease 1 expression. PLoS ONE 7:e37693. doi:10.1371/journal.pone.0037693
-
(2012)
PLoS ONE
, vol.7
-
-
Huang, W.1
-
19
-
-
0037204544
-
Prediction of drug solubility from structure
-
DOI 10.1016/S0169-409X(02)00008-X, PII S0169409X0200008X
-
Jorgensen WL, Duffy EM (2002) Prediction of drug solubility from structure. Adv Drug Deliver Rev 54:355-366 (Pubitemid 34260958)
-
(2002)
Advanced Drug Delivery Reviews
, vol.54
, Issue.3
, pp. 355-366
-
-
Jorgensen, W.L.1
Duffy, E.M.2
-
20
-
-
33645941402
-
The OPLS [optimized potentials for liquid simulations] potential functions for proteins, energy minimizations for crystals of cyclic peptides and crambin
-
Jorgensen WL, Tirado-Rives J (1988) The OPLS [optimized potentials for liquid simulations] potential functions for proteins, energy minimizations for crystals of cyclic peptides and crambin. J Am Chem Soc 110:1657-1666
-
(1988)
J Am Chem Soc
, vol.110
, pp. 1657-1666
-
-
Jorgensen, W.L.1
Tirado-Rives, J.2
-
21
-
-
0029912748
-
Development and testing of the OPLS all-atom force field on conformational energetics and properties of organic liquids
-
DOI 10.1021/ja9621760, PII S0002786396021762
-
Jorgensen WL, Maxwell DS, Tirado-Rives J (1996) Development and testing of the OPLS all-atom force field on conformational energetics and properties of organic liquids. J Am Chem Soc 118:11225-11236. doi:10.1021/ja9621760 (Pubitemid 26399746)
-
(1996)
Journal of the American Chemical Society
, vol.118
, Issue.45
, pp. 11225-11236
-
-
Jorgensen, W.L.1
Maxwell, D.S.2
Tirado-Rives, J.3
-
22
-
-
69949157311
-
Pharmacokinetics and pharmacodynamics of broccoli sprouts on the suppression of prostate cancer in transgenic adenocarcinoma of mouse prostate (TRAMP) mice: Implication of induction of Nrf2, HO-1 and apoptosis and the suppression of Akt-dependent kinase pathway
-
doi:10.1007/s11095-009-9948-5
-
Keum Y-S et al (2009) Pharmacokinetics and pharmacodynamics of broccoli sprouts on the suppression of prostate cancer in transgenic adenocarcinoma of mouse prostate (TRAMP) mice: implication of induction of Nrf2, HO-1 and apoptosis and the suppression of Akt-dependent kinase pathway. Pharm Res 26:2324-2331. doi:10.1007/s11095-009-9948-5
-
(2009)
Pharm Res
, vol.26
, pp. 2324-2331
-
-
Keum, Y.-S.1
-
23
-
-
84885652402
-
Raf and PI3K are themolecular targets for the antimetastatic effect of luteolin
-
doi:10.1002/ptr.4888
-
Kim HY et al (2012) Raf and PI3K are themolecular targets for the antimetastatic effect of luteolin. Phytother Res. doi:10.1002/ptr.4888
-
(2012)
Phytother Res
-
-
Kim, H.Y.1
-
24
-
-
33847656296
-
Morin inhibits the growth of human leukemia HL-60 cells via cell cycle arrest and induction of apoptosis through mitochondria dependent pathway
-
doi:10.1002/ptr.4888
-
Kuo H-M et al (2007) Morin inhibits the growth of human leukemia HL-60 cells via cell cycle arrest and induction of apoptosis through mitochondria dependent pathway. Anticancer Res 27:395-405. doi:10.1002/ptr.4888
-
(2007)
Anticancer Res
, vol.27
, pp. 395-405
-
-
Kuo, H.-M.1
-
25
-
-
55449124465
-
Luteolin, a flavonoid with potentials for cancer prevention and therapy
-
Lin Y et al (2008) Luteolin, a flavonoid with potentials for cancer prevention and therapy. Curr Cancer Drug Targets 8(7):634-646
-
(2008)
Curr Cancer Drug Targets
, vol.8
, Issue.7
, pp. 634-646
-
-
Lin, Y.1
-
26
-
-
84895514429
-
The roles of endoplasmic reticulum stress and mitochondrial apoptotic signaling pathway in quercetin-mediated cell death of human prostate cancer PC-3 cells
-
doi:10.1002/tox.21769
-
Liu KC et al (2012) The roles of endoplasmic reticulum stress and mitochondrial apoptotic signaling pathway in quercetin-mediated cell death of human prostate cancer PC-3 cells. Environ Toxicol. doi:10.1002/tox.21769
-
(2012)
Environ Toxicol
-
-
Liu, K.C.1
-
27
-
-
62749165351
-
Distribution and biological activities of the flavonoid luteolin
-
Lopez-Lazaro M (2009) Distribution and biological activities of the flavonoid luteolin. Mini Rev Med Chem 9:31-59
-
(2009)
Mini Rev Med Chem
, vol.9
, pp. 31-59
-
-
Lopez-Lazaro, M.1
-
28
-
-
43049131769
-
Targeting the PI3K/Akt/mTOR pathway: Effective combinations and clinical considerations
-
doi:10.1016/j.drup.2007.11.003
-
LoPiccolo J et al (2008) Targeting the PI3K/Akt/mTOR pathway: effective combinations and clinical considerations. Drug Resist Updat 11:32. doi:10.1016/j.drup.2007.11.003
-
(2008)
Drug Resist Updat
, vol.11
, pp. 32
-
-
LoPiccolo, J.1
-
29
-
-
8644219619
-
Influence of molecular flexibility and polar surface area metrics on oral bioavailability in the rat
-
DOI 10.1021/jm0306529
-
Lu JJ et al (2004) Influence of molecular flexibility and polar surface area metrics on oral bioavailability in the rat. J Med Chem 47:6104-6107 (Pubitemid 39507351)
-
(2004)
Journal of Medicinal Chemistry
, vol.47
, Issue.24
, pp. 6104-6107
-
-
Lu, J.J.1
Crimin, K.2
Goodwin, J.T.3
Crivori, P.4
Orrenius, C.5
Xing, L.6
Tandler, P.J.7
Vidmar, T.J.8
Amore, B.M.9
Wilson, A.G.E.10
Stouten, P.F.W.11
Burton, P.S.12
-
30
-
-
84874556145
-
Large FK506-binding proteins shape the pharmacology of rapamycin
-
doi:10.1128/MCB.00678-12
-
März AM et al (2013) Large FK506-binding proteins shape the pharmacology of rapamycin. Mol Cell Biol 33:1357-1367. doi:10.1128/MCB.00678-12
-
(2013)
Mol Cell Biol
, vol.33
, pp. 1357-1367
-
-
März, A.M.1
-
31
-
-
84868147312
-
Selective apoptotic effects of piceatannol and myricetin in human cancer cells
-
doi:10.1002/jat.1725
-
Morales P, Haza AI (2012) Selective apoptotic effects of piceatannol and myricetin in human cancer cells. J Appl Toxicol 32:986-993. doi:10.1002/jat.1725
-
(2012)
J Appl Toxicol
, vol.32
, pp. 986-993
-
-
Morales, P.1
Haza, A.I.2
-
32
-
-
62549100016
-
Targeted therapy for advanced prostate cancer: Inhibition of the PI3K/Akt/mTOR pathway
-
Morgan TM, Koreckij TD, Corey E (2009) Targeted therapy for advanced prostate cancer: inhibition of the PI3K/Akt/mTOR pathway. Curr Cancer Drug Targets 9(2):237-249
-
(2009)
Curr Cancer Drug Targets
, vol.9
, Issue.2
, pp. 237-249
-
-
Morgan, T.M.1
Koreckij, T.D.2
Corey, E.3
-
33
-
-
24044551995
-
PI3K/Akt/mTOR pathway as a target for cancer therapy
-
DOI 10.1097/01.cad.0000173476.67239.3b
-
Morgensztern D, McLeod HL (2005) PI3K/Akt/mTOR pathway as a target for cancer therapy. Anticancer Drugs 16:797-803 (Pubitemid 41215743)
-
(2005)
Anti-Cancer Drugs
, vol.16
, Issue.8
, pp. 797-803
-
-
Morgensztern, D.1
McLeod, H.L.2
-
34
-
-
77649204688
-
Selectively nonselective kinase inhibition: Striking the right balance
-
doi:10.1021/jm901132v
-
Morphy R (2010) Selectively nonselective kinase inhibition: striking the right balance. J Med Chem 53:1413-1437. doi:10.1021/jm901132v
-
(2010)
J Med Chem
, vol.53
, pp. 1413-1437
-
-
Morphy, R.1
-
35
-
-
84055217593
-
Discovery of novel, potent, and selective inhibitors of 3-phosphoinositide-dependent kinase (PDK1)
-
doi:10.1021/jm201019k
-
Murphy ST et al (2011) Discovery of novel, potent, and selective inhibitors of 3-phosphoinositide-dependent kinase (PDK1). J Med Chem 54:8490-8500. doi:10.1021/jm201019k
-
(2011)
J Med Chem
, vol.54
, pp. 8490-8500
-
-
Murphy, S.T.1
-
36
-
-
79960192285
-
Phospshoinositide 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) dual inhibitors: Discovery and structureâ€"activity relationships of a series of quinoline and quinoxaline derivatives
-
doi:10.1021/jm200386s
-
Nishimura N et al (2011) Phospshoinositide 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) dual inhibitors: discovery and structure†"activity relationships of a series of quinoline and quinoxaline derivatives. J Med Chem 54:4735-4751. doi:10.1021/jm200386s
-
(2011)
J Med Chem
, vol.54
, pp. 4735-4751
-
-
Nishimura, N.1
-
37
-
-
32944457518
-
mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt
-
DOI 10.1158/0008-5472.CAN-05-2925
-
O'Reilly KE et al (2006) mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt. Cancer Res 66:1500-1508 (Pubitemid 43259931)
-
(2006)
Cancer Research
, vol.66
, Issue.3
, pp. 1500-1508
-
-
O'Reilly, K.E.1
Rojo, F.2
She, Q.-B.3
Solit, D.4
Mills, G.B.5
Smith, D.6
Lane, H.7
Hofmann, F.8
Hicklin, D.J.9
Ludwig, D.L.10
Baselga, J.11
Rosen, N.12
-
38
-
-
78650753990
-
Molecular docking study on anticancer activity of plant-derived natural products
-
doi:10.1007/s00044-009-9233-5
-
Phosrithong N, Ungwitayatorn J (2010) Molecular docking study on anticancer activity of plant-derived natural products. Med Chem Res 19:817-835. doi:10.1007/s00044-009-9233-5
-
(2010)
Med Chem Res
, vol.19
, pp. 817-835
-
-
Phosrithong, N.1
Ungwitayatorn, J.2
-
39
-
-
84867651619
-
Quercetin inhibits angiogenesis mediated human prostate tumor growth by targeting VEGFR-2 regulated AKT/mTOR/P70S6K signaling pathways
-
doi:10.1371/journal.pone.0047516
-
Pratheeshkumar P et al (2012) Quercetin inhibits angiogenesis mediated human prostate tumor growth by targeting VEGFR-2 regulated AKT/mTOR/P70S6K signaling pathways. PLoS ONE 7:e47516. doi:10.1371/journal.pone.0047516
-
(2012)
PLoS ONE
, vol.7
-
-
Pratheeshkumar, P.1
-
40
-
-
79951846076
-
Identification of antrocin from Antrodia camphorata as a selective and novel class of small molecule inhibitor of Akt/mTOR signaling in metastatic breast cancer MDA-MB-231 cells
-
doi:10.1021/tx100318m
-
Rao YK et al (2010) Identification of antrocin from Antrodia camphorata as a selective and novel class of small molecule inhibitor of Akt/mTOR signaling in metastatic breast cancer MDA-MB-231 cells. Chem Res Toxicol 24:238-245. doi:10.1021/tx100318m
-
(2010)
Chem Res Toxicol
, vol.24
, pp. 238-245
-
-
Rao, Y.K.1
-
41
-
-
78650519061
-
The natural compounds atraric acid and N-butylbenzene-sulfonamide as antagonists of the human androgen receptor and inhibitors of prostate cancer cell growth
-
doi:10.1016/j.mce.2010.09.013
-
Roell D, Baniahmad A (2011) The natural compounds atraric acid and N-butylbenzene-sulfonamide as antagonists of the human androgen receptor and inhibitors of prostate cancer cell growth Mol. Cell Endocrinol 332:1-8. doi:10.1016/j.mce.2010.09.013
-
(2011)
Mol. Cell Endocrinol
, vol.332
, pp. 1-8
-
-
Roell, D.1
Baniahmad, A.2
-
42
-
-
33645743524
-
Using chemopreventive agents to enhance the efficacy of cancer therapy
-
Sarkar FH, Li Y (2006) Using chemopreventive agents to enhance the efficacy of cancer therapy. Cancer Res 66:3347-3350
-
(2006)
Cancer Res
, vol.66
, pp. 3347-3350
-
-
Sarkar, F.H.1
Li, Y.2
-
43
-
-
68049137909
-
Targeting the PI3K/AKT pathway for the treatment of prostate cancer
-
doi:10.1158/1078-0432.CCR-08-0125
-
Sarker D et al (2009) Targeting the PI3K/AKT pathway for the treatment of prostate cancer. Clin Cancer Res 15:4799-4805. doi:10.1158/1078-0432.CCR-08- 0125
-
(2009)
Clin Cancer Res
, vol.15
, pp. 4799-4805
-
-
Sarker, D.1
-
44
-
-
77952415408
-
Prediction of absolute solvation free energies using molecular dynamics free energy perturbation and the OPLS force field
-
doi:10.1021/ct900587b
-
Shivakumar D et al (2010) Prediction of absolute solvation free energies using molecular dynamics free energy perturbation and the OPLS force field. J Chem Theory Comput 6:1509-1519. doi:10.1021/ct900587b
-
(2010)
J Chem Theory Comput
, vol.6
, pp. 1509-1519
-
-
Shivakumar, D.1
-
45
-
-
62449233418
-
Sulforaphane inhibits prostate carcinogenesis and pulmonary metastasis in TRAMP mice in association with increased cytotoxicity of natural killer cells
-
doi:10.1158/0008-5472.CAN-08-3502
-
Singh SV et al (2009) Sulforaphane inhibits prostate carcinogenesis and pulmonary metastasis in TRAMP mice in association with increased cytotoxicity of natural killer cells. Cancer Res 69:2117-2125. doi:10.1158/0008-5472.CAN-08- 3502
-
(2009)
Cancer Res
, vol.69
, pp. 2117-2125
-
-
Singh, S.V.1
-
46
-
-
72149083011
-
Morin fosters apoptosis in experimental hepatocellular carcinogenesis model
-
doi:10.1016/j.cbi.2009.11.011
-
Sivaramakrishnan V, Devaraj SN (2010) Morin fosters apoptosis in experimental hepatocellular carcinogenesis model. Chem-Biol Interact 183:284-292. doi:10.1016/j.cbi.2009.11.011
-
(2010)
Chem-Biol Interact
, vol.183
, pp. 284-292
-
-
Sivaramakrishnan, V.1
Devaraj, S.N.2
-
47
-
-
84861429437
-
Potential anticancer activity of myricetin in human T24 bladder cancer cells both in vitro and in vivo
-
doi:10.1080/01635581.2012.665564
-
Sun F et al (2012) Potential anticancer activity of myricetin in human T24 bladder cancer cells both in vitro and in vivo. Nutr Cancer 64:599-606. doi:10.1080/01635581.2012.665564
-
(2012)
Nutr Cancer
, vol.64
, pp. 599-606
-
-
Sun, F.1
-
48
-
-
84899418879
-
Inhibition studies of naturally occurring terpene based compounds with cyclin-dependent kinase 2 enzyme
-
doi:10.4172/jcsb.1000092
-
Sunil H (2012) Inhibition studies of naturally occurring terpene based compounds with cyclin-dependent kinase 2 enzyme. J Comput Syst Sci doi:10.4172/jcsb.1000092
-
(2012)
J Comput Syst Sci
-
-
Sunil, H.1
-
49
-
-
84861442939
-
Quercetin increased the antiproliferative activity of green tea polyphenol (-)-epigallocatechin gallate in prostate cancer cells
-
doi:10.1080/01635581.2012.661514
-
Wang P, Heber D, Henning SM (2012) Quercetin increased the antiproliferative activity of green tea polyphenol (-)-epigallocatechin gallate in prostate cancer cells. Nutr Cancer 64:580-587. doi:10.1080/01635581.2012. 661514
-
(2012)
Nutr Cancer
, vol.64
, pp. 580-587
-
-
Wang, P.1
Heber, D.2
Henning, S.M.3
-
50
-
-
79954592882
-
mTOR signaling, function, novel inhibitors, and therapeutic targets
-
doi:10.2967/jnumed.111.089623
-
Watanabe R, Wei L, Huang J (2011) mTOR signaling, function, novel inhibitors, and therapeutic targets. J Nucl Med 52:497-500. doi:10.2967/jnumed. 111.089623
-
(2011)
J Nucl Med
, vol.52
, pp. 497-500
-
-
Watanabe, R.1
Wei, L.2
Huang, J.3
-
51
-
-
75849118878
-
Targeting the PI3K signaling pathway in cancer
-
doi:10.1016/j.gde.2009.11.002
-
Wong K-K, Engelman JA, Cantley LC (2010) Targeting the PI3K signaling pathway in cancer. Curr Opin Genet Dev 20:87-90. doi:10.1016/j.gde.2009.11.002
-
(2010)
Curr Opin Genet Dev
, vol.20
, pp. 87-90
-
-
Wong, K.-K.1
Engelman, J.A.2
Cantley, L.C.3
-
52
-
-
84898978897
-
Myricetin induces apoptosis in Hepg2 cells through Akt/P70s6 k/bad signaling and mitochondrial apoptotic pathway
-
Epub ahead of print
-
Zhang X, et al (2013) Myricetin induces apoptosis in Hepg2 cells through Akt/P70s6 k/bad signaling and mitochondrial apoptotic pathway. Anticancer Agents Med Chem. [Epub ahead of print]
-
(2013)
Anticancer Agents Med Chem
-
-
Zhang, X.1
-
53
-
-
34249828198
-
The PI3K/Akt pathway and its downstream transcriptional factors as targets for chemoprevention
-
DOI 10.2174/156800907780809741
-
Zhang X, Jin B, Huang C (2007) The PI3K/Akt pathway and its downstream transcriptional factors as targets for chemoprevention. Curr Cancer Drug Targets 7:305-316 (Pubitemid 46849235)
-
(2007)
Current Cancer Drug Targets
, vol.7
, Issue.4
, pp. 305-316
-
-
Zhang, X.1
Jin, B.2
Huang, C.3
-
55
-
-
84876570722
-
Feasibility of using molecular docking-based virtual screening for searching dual target kinase inhibitors
-
doi:10.1021/ci400065e
-
Zhou S, Li Y, Hou T (2013) Feasibility of using molecular docking-based virtual screening for searching dual target kinase inhibitors. J Chem Inf Model. doi:10.1021/ci400065e
-
(2013)
J Chem Inf Model
-
-
Zhou, S.1
Li, Y.2
Hou, T.3
-
56
-
-
84859881549
-
Quercetin induces the apoptosis of human PC-3 cells
-
Zhu Q et al (2011) Quercetin induces the apoptosis of human PC-3 cells. Natl J Androl 17(9):790-793
-
(2011)
Natl J Androl
, vol.17
, Issue.9
, pp. 790-793
-
-
Zhu, Q.1
|