Increased macromolecular damage due to oxidative stress in the neocortex and hippocampus of WNIN/Ob, a novel rat model of premature aging

Neuroscience

Volumn 269, Issue , 2014, Pages 256-264

  Sinha, J K ^a   Ghosh, S ^a   Swain, U ^b   Giridharan, N V ^a   Raghunath, M ^a  

^a NATIONAL INSTITUTE OF NUTRITION   (India)

^b JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY   (India)

Author keywords

Antioxidant enzyme activity; Brain aging; Comet assay; DNA damage; Obesity; Reduced lifespan

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CATALASE; DOUBLE STRANDED DNA; MALONALDEHYDE; SINGLE STRANDED DNA; SUPEROXIDE DISMUTASE;

ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DOUBLE STRANDED DNA BREAK; ENZYME ACTIVITY; HIPPOCAMPUS; LIFESPAN; LIPID PEROXIDATION; MACROMOLECULE; MALE; METABOLIC SYNDROME X; NEOCORTEX; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PREMATURE AGING; PRIORITY JOURNAL; RAT; SENESCENCE; SINGLE STRANDED DNA BREAK; TISSUE HOMOGENATE; TISSUE PREPARATION; AGE; ANIMAL; DISEASE MODEL; METABOLISM; OBESITY; PATHOPHYSIOLOGY; PHYSIOLOGY;

AGE FACTORS; AGING, PREMATURE; ANIMALS; CATALASE; DISEASE MODELS, ANIMAL; DNA DAMAGE; HIPPOCAMPUS; LIPID PEROXIDATION; MALE; NEOCORTEX; OBESITY; OXIDATIVE STRESS; RATS; SUPEROXIDE DISMUTASE;

EID: 84899118660     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2014.03.040     Document Type: Article

References (55)

1. Aebi H. Catalase in vitro. Methods Enzymol 1984, 105:121-126.
2. Alfadda A.A., Benabdelkamel H., Masood A., Moustafa A., Sallam R., Bassas A., Duncan M. Proteomic analysis of mature adipocytes from obese patients in relation to aging. Exp Gerontol 2013, 48:1196-1203.
3. Aliahmat N.S., Noor M.R., Yusof W.J., Makpol S., Ngah W.Z., Yusof Y.A. Antioxidant enzyme activity and malondialdehyde levels can be modulated by Piper betle, tocotrienol rich fraction and Chlorella vulgaris in aging C57BL/6 mice. Clinics 2012, 67:1447-1454.
4. Araujo D.M., Santos G.F., Nardi A.E. Binge eating disorder and depression: a systematic review. World J Biol Psychiatry 2010, 11:199-207.
5. Arterburn D., Westbrook E.O., Ludman E.J., Operskalski B., Linde J.A., Rohde P., Jeffery R.W., Simon G.E. Relationship between obesity, depression, and disability in middle-aged women. Obes Res Clin Pract 2012, 6:e197-e206.
6. Bandaru P., Rajkumar H., Nappanveettil G. Altered or impaired immune response upon vaccination in WNIN/Ob rats. Vaccine 2011, 29:3038-3042.
7. Barzilai A., Yamamoto K. DNA damage responses to oxidative stress. DNA Repair 2004, 3:1109-1115.
8. Braidy N., Guillemin G.J., Mansour H., Chan-Ling T., Poljak A., Grant R. Age related changes in NAD+ metabolism oxidative stress and Sirt1 activity in wistar rats. PLoS One 2011, 6:e19194.
9. Clausen A., Doctrow S., Baudry M. Prevention of cognitive deficits and brain oxidative stress with superoxide dismutase/catalase mimetics in aged mice. Neurobiol Aging 2010, 31:425-433.
10. de Zwaan M. Binge eating disorder and obesity. Int J Obes Relat Metab Disord 2001, 25(Suppl. 1):S51-S55.
11. Finkel T., Holbrook N.J. Oxidants, oxidative stress and the biology of ageing. Nature 2000, 408:239-247.
12. Freitas A.A., de Magalhaes J.P. A review and appraisal of the DNA damage theory of ageing. Mutat Res 2011, 728:12-22.
13. Furukawa S., Fujita T., Shimabukuro M., Iwaki M., Yamada Y., Nakajima Y., Nakayama O., Makishima M., Matsuda M., Shimomura I. Increased oxidative stress in obesity and its impact on metabolic syndrome. J Clin Investig 2004, 114:1752-1761.
14. Garcia J.J., Pinol-Ripoll G., Martinez-Ballarin E., Fuentes-Broto L., Miana-Mena F.J., Venegas C., Caballero B., Escames G., Coto-Montes A., Acuna-Castroviejo D. Melatonin reduces membrane rigidity and oxidative damage in the brain of SAMP8 mice. Neurobiol Aging 2011, 32:2045-2054.
15. Garinis G.A., van der Horst G.T., Vijg J., Hoeijmakers J.H. DNA damage and ageing: new-age ideas for an age-old problem. Nat Cell Biol 2008, 10:1241-1247.
16. Giridharan N.V. Animal models of obesity & their usefulness in molecular approach to obesity. Indian J Med Res 1998, 108:225-242.
17. Gladyshev V.N. On the cause of aging and control of lifespan: heterogeneity leads to inevitable damage accumulation, causing aging; control of damage composition and rate of accumulation define lifespan. BioEssays 2012, 34:925-929.
18. Goncharova N.D., Yu Marenin V., Vengerin A.A. Age-related changes in the reliability of antioxidant enzyme defense in monkeys with different types of adaptive behavior. Curr Aging Sci 2013, 6:163-169.
19. Haddadi M., Jahromi S.R., Sagar B.K., Patil R.K., Shivanandappa T., Ramesh S.R. Brain aging, memory impairment and oxidative stress: a study in Drosophila melanogaster. Behav Brain Res 2013, 259C:60-69.
20. Harishankar N., Kumar P.U., Sesikeran B., Giridharan N. Obesity associated pathophysiological & histological changes in WNIN obese mutant rats. Indian J Med Res 2011, 134:330-340.
21. Harrington J., Lee-Chiong T. Obesity and aging. Clin Chest Med 2009, 30:609-614.
22. Hasty P., Campisi J., Hoeijmakers J., van Steeg H., Vijg J. Aging and genome maintenance: lessons from the mouse?. Science 2003, 299:1355-1359.
23. Head E., Liu J., Hagen T.M., Muggenburg B.A., Milgram N.W., Ames B.N., Cotman C.W. Oxidative damage increases with age in a canine model of human brain aging. J Neurochem 2002, 82:375-381.
24. Kalashikam R.R., Battula K.K., Kirlampalli V., Friedman J.M., Nappanveettil G. Obese locus in WNIN/obese rat maps on chromosome 5 upstream of leptin receptor. PLoS One 2013, 8:e77679.
25. Kalashikam R.R., Inagadapa P.J.N., Thomas A.E., Jeyapal S., Giridharan N.V., Raghunath M. Leptin gene promoter DNA methylation in WNIN obese mutant rats. Lipids Health Dis 2014, 13:25.
26. Larsen P.L. Aging and resistance to oxidative damage in Caenorhabditis elegans. Proc Natl Acad Sci U S A 1993, 90:8905-8909.
27. Levine R.L., Garland D., Oliver C.N., Amici A., Climent I., Lenz A.G., Ahn B.W., Shaltiel S., Stadtman E.R. Determination of carbonyl content in oxidatively modified proteins. Methods Enzymol 1990, 186:464-478.
28. Mandavilli B.S., Rao K.S. Neurons in the cerebral cortex are most susceptible to DNA-damage in aging rat brain. Biochem Mol Biol Int 1996, 40:507-514.
29. Marcus D.L., Thomas C., Rodriguez C., Simberkoff K., Tsai J.S., Strafaci J.A., Freedman M.L. Increased peroxidation and reduced antioxidant enzyme activity in Alzheimer's disease. Exp Neurol 1998, 150:40-44.
30. Marosi K., Bori Z., Hart N., Sarga L., Koltai E., Radak Z., Nyakas C. Long-term exercise treatment reduces oxidative stress in the hippocampus of aging rats. Neuroscience 2012, 226:21-28.
31. Michaud M., Balardy L., Moulis G., Gaudin C., Peyrot C., Vellas B., Cesari M., Nourhashemi F. Proinflammatory cytokines, aging, and age-related diseases. J Am Med Dir Assoc 2013, 14:877-882.
32. Misra H.P., Fridovich I. The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase. J Biol Chem 1972, 247:3170-3175.
33. Mitchell J.E., Mussell M.P. Comorbidity and binge eating disorder. Addict Behav 1995, 20:725-732.
34. Mori N., Goto S. Estimation of the single stranded region in the nuclear DNA of mouse tissues during aging with special reference to the brain. Arch Gerontol Geriatr 1982, 1:143-150.
35. Moskalev A.A., Shaposhnikov M.V., Plyusnina E.N., Zhavoronkov A., Budovsky A., Yanai H., Fraifeld V.E. The role of DNA damage and repair in aging through the prism of Koch-like criteria. Ageing Res Rev 2013, 12:661-684.
36. Nie B., Gan W., Shi F., Hu G.X., Chen L.G., Hayakawa H., Sekiguchi M., Cai J.P. Age-dependent accumulation of 8-oxoguanine in the DNA and RNA in various rat tissues. Oxidative Med Cell Longevity 2013, 2013:303181.
37. Ohkawa H., Ohishi N., Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979, 95:351-358.
38. Pandey K.B., Rizvi S.I. Markers of oxidative stress in erythrocytes and plasma during aging in humans. Oxidative Med Cell Longevity 2010, 3:2-12.
39. Petursdottir A.L., Farr S.A., Morley J.E., Banks W.A., Skuladottir G.V. Lipid peroxidation in brain during aging in the senescence-accelerated mouse (SAM). Neurobiol Aging 2007, 28:1170-1178.
40. Price G.B., Modak S.P., Makinodan T. Age-associated changes in the DNA of mouse tissue. Science 1971, 171:917-920.
41. Reddy G.B., Vasireddy V., Mandal M.N., Tiruvalluru M., Wang X.F., Jablonski M.M., Nappanveettil G., Ayyagari R. A novel rat model with obesity-associated retinal degeneration. Invest Ophthalmol Vis Sci 2009, 50:3456-3463.
42. Rodriguez-Martinez E., Martinez F., Espinosa-Garcia M.T., Maldonado P., Rivas-Arancibia S. Mitochondrial dysfunction in the hippocampus of rats caused by chronic oxidative stress. Neuroscience 2013, 252:384-395.
43. Rutten B.P., Schmitz C., Gerlach O.H., Oyen H.M., de Mesquita E.B., Steinbusch H.W., Korr H. The aging brain: accumulation of DNA damage or neuron loss?. Neurobiol Aging 2007, 28:91-98.
44. Silhol M., Arancibia S., Perrin D., Maurice T., Alliot J., Tapia-Arancibia L. Effect of aging on brain-derived neurotrophic factor, proBDNF, and their receptors in the hippocampus of Lou/C rats. Rejuvenation Res 2008, 11:1031-1040.
45. Silhol M., Bonnichon V., Rage F., Tapia-Arancibia L. Age-related changes in brain-derived neurotrophic factor and tyrosine kinase receptor isoforms in the hippocampus and hypothalamus in male rats. Neuroscience 2005, 132:613-624.
46. Singh B.K., Kumar A., Ahmad I., Kumar V., Patel D.K., Jain S.K., Singh C. Oxidative stress in zinc-induced dopaminergic neurodegeneration: implications of superoxide dismutase and heme oxygenase-1. Free Radical Res 2011, 45:1207-1222.
47. Sinha J.K., Ghosh S. Scoring more than ten plus century - antiquity in gerontology?. Indian J Med Res 2010, 131:586-587.
48. Sinha JK, Ghosh S, Raghunath M (2014) A review on progeria: a rare genetic premature aging disorder. Indian J Med Res (Accepted).
49. Sinha J.K., Giridharan N.V., Raghunath M. Can systemic and central IGF1 and BDNF levels play a role in decreasing the longevity of WNIN obese mutant rats?. Int J Dev Neurosci 2012, 30:648-649.
50. Swain U., Subba Rao K. Study of DNA damage via the comet assay and base excision repair activities in rat brain neurons and astrocytes during aging. Mech Ageing Dev 2011, 132:374-381.
51. Telch C.F., Stice E. Psychiatric comorbidity in women with binge eating disorder: prevalence rates from a non-treatment-seeking sample. J Consult Clin Psychol 1998, 66:768-776.
52. Torres S.J., Nowson C.A. Relationship between stress, eating behavior, and obesity. Nutrition 2007, 23:887-894.
53. Tzanetakou I.P., Katsilambros N.L., Benetos A., Mikhailidis D.P., Perrea D.N. "Is obesity linked to aging?": adipose tissue and the role of telomeres. Ageing Res Rev 2012, 11:220-229.
54. Yanar K., Aydin S., Cakatay U., Mengi M., Buyukpinarbasili N., Atukeren P., Sitar M.E., Sonmez A., Uslu E. Protein and DNA oxidation in different anatomic regions of rat brain in a mimetic ageing model. Basic Clin Pharmacol Toxicol 2011, 109:423-433.
55. Zhu H., van der Harst P. Telomere biology in senescence and aging: focus on cardiovascular traits. Inflammation, advancing age and nutrition 2014, 71-84. Academic Press, San Diego, Chapter 7. I. Rahman, D. Bagchi (Eds.).