Protein and DNA oxidation in different anatomic regions of rat brain in a mimetic ageing model

Basic and Clinical Pharmacology and Toxicology

Volumn 109, Issue 6, 2011, Pages 423-433

  Yanar, Karolin ^a   Aydin, Seval ^a   Çakatay, Ufuk ^a   Mengi, Murat ^a   Buyukpinarbaşili, Nur ^b   Atukeren, Pinar ^a   Sitar, Mustafa E ^a   Sönmez, Asli ^c   Uslu, Ezel ^a  

^a ISTANBUL UNIVERSITY   (Turkey)

^b Yedikule Teaching Hospital   (Turkey)

^c ISTANBUL UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; GALACTOSE; LIPID; PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOLOGICAL MODEL; BRAIN DEGENERATION; CONTROLLED STUDY; FRONTAL LOBE; GLIA CELL; HIPPOCAMPUS; MALE; NERVE CELL; NONHUMAN; OXIDATIVE STRESS; PARIETAL LOBE; PRIORITY JOURNAL; PROTEIN CARBONYLATION; RAT; SPATIAL MEMORY;

AGING; ANIMALS; BIOLOGICAL MARKERS; BRAIN; DEOXYGUANOSINE; DISEASE MODELS, ANIMAL; DNA DAMAGE; FRONTAL LOBE; GALACTOSE; HIPPOCAMPUS; LIPID PEROXIDATION; LIPID PEROXIDES; MALE; MAZE LEARNING; OXIDATION-REDUCTION; OXIDATIVE STRESS; PARIETAL LOBE; PROTEIN CARBONYLATION; PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; SPATIAL BEHAVIOR; SULFHYDRYL COMPOUNDS;

RATTUS; RODENTIA;

EID: 81255160774     PISSN: 17427835     EISSN: 17427843     Source Type: Journal    
DOI: 10.1111/j.1742-7843.2011.00756.x     Document Type: Article

References (59)

1. Oliveira BF, Nogueira-Machado JA, Chaves MM. The role of oxidative stress in the aging process. Sci World J 2010;10:1121-8.
2. Çakatay U, Aydin S, Yanar K, Uzun H. Gender-dependent variations in systemic biomarkers of oxidative protein, DNA, and lipid damage in aged rats. Aging Male 2010;13:51-8.
3. Descamps-Latscha B, Drüeke T, Witko-Sarsat V. Dialysis induced oxidative stress. Biological aspacts, clinical consequences and therapy. Semin Dial 2001;14:193-9.
4. Droge W. Oxidative stress and aging: is aging a cysteine deficiency syndrome? Phil Trans R Soc B 2005;360:2355-72.
5. Harman D. The biologic clock: the mitochondria? J Am Geriatric Soc 1972;20:145-7.
6. Sasaki T. Analysis of aging-related oxidative stress status in normal aging animals and development of anti-aging interventions. Yakugaku Zasshi 2010;13:29-42.
7. Stadtman ER. Protein modification in aging. Free Radical Res 2006;40:1250-8.
8. Çakatay U. Protein redox-regulation mechanisms in aging. In: Bondy SC, Maise K (eds). Aging and Age-Related Disorders. Springer Science + Business Media, Berlin, 2010;1-24.
9. Dkhar P, Sharma R. Effect of dimethylsulphoxide and curcumin on protein carbonyls and reactive oxygen species of cerebral hemispheres of mice as a function of age. Int J Devl Neurosci 2010;28:351-7.
10. Hsieh HM, Wu WM, Hu ML. Soy isoflavones attenuate oxidative stress and improve parameters related to aging and Alzheimer's disease in C57BL/6J mice treated with d-galactose. Food Chem Toxicol 2009;47:625-32.
11. Chen B, Zhong Y, Peng W, Sun Y, Kong W. Age-related changes in the central auditory system: comparison of d-galactose-induced aging rats and naturally aging rats. Brain Res 2010;1344:43-53.
12. JunDe Z, ZiJang Y, ChaoSheng K, Yan Y. Effect of intracerebroventricular injection of noggin on learning and memory and neurogenesis in hippocampal dentate gyms of d-galactose induced aging mice. J Shandong Univ (Health Science) 2009;47:72-4.
13. Lei M, Hua X, Xiao M, Ding J, Han Q, Hu G. Impairments of astrocytes are involved in the d-galactose induced brain aging. Biochem Biophys Res Commun 2008;369:1082-7.
14. D'Hooge R, De Deyn PP. Applications of the Morris water maze in the study of learning and memory. Brain Res Brain Res Rev 2001;36:60-90.
15. Reznick AZ, Packer L. Oxidative damage to proteins: spectrophotometric method for carbonyl assay. Methods Enzymol 1994;233:357-63.
16. Bradford MA. Rapid sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72:248-54.
17. Witko-Sarsat V, Friedlander M, Capeillere-Blandin C, Nguyen-Khoa T, Nguyen AT, Zingraff J et al. Advanced oxidation protein products as a novel marker of oxidative stress in uremia. Kidney Int 1996;49:1304-13.
18. Sedlak J, Lindsay RH. Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent. Anal Biochem 1968;25:192-205.
19. Wolff SP. Ferrous ion oxidation in presence of ferric ion indicator xylenol orange for measurement of hydroperoxides. Methods Enzymol 1994;233:182-9.
20. Benzi G, Pastoris O, Marzatico F, Villa RF. Influence of aging and drug treatment on the cerebral glutathione system. Neurobiol Aging 1998;9:371-5.
21. Cui X, Zuo P, Zhang Q, Li X, Hu Y, Long J et al. Chronic systemic d-galactose exposure induces memory loss, neurodegeneration, and oxidative damage in mice: protective effects of R-alpha-lipoic acid. J Neurosci Res 2006;84:647-54.
22. Gutman J. Psyconeurobiology & Glutathione. In: Schettini S (ed.). GSH Your Body's Most Powerful Protector Glutathione, Chapter 20. G&S Health Books Inc., Montreal, 2008;191-93.
23. Uzun H, Kayali R, Cakatay U. The chance of gender dependency of oxidation of brain proteins in aged rats. Arch Gerontol Geriatr 2010;50:16-9.
24. Amerand A, Vettier A, Sebert P, Conn-moisa C. In vitro effect of hydrostatic pressure exposure on hydroxyl radical production in fish red muscle. Redox Rep 2005;10:1-4.
25. Kumar A, Prakash A, Dogra S. Naringin alleviates cognitive impairment, mitochondrial dysfunction and oxidative stress induced by d-galactose in mice. Food Chem Toxicol 2010;48: 626-32.
26. Su Y, Sun H, Fang J, Hu G, Xiao M. Brain mitochondrial dysfunction in ovariectomized mice injected with d-galactose. Neurochem Res 2010;35:399-404.
27. Zhang X, Liu W, Niu X, An L. Systemic administration of catalpol prevents d-galactose induced mitochondrial dysfunction in mice. Neurosci Lett 2010;473:224-8.
28. Pérez VI, Buffenstein R, Masamsetti V, Leonard S, Salmon AB, Mele J et al. Protein stability and resistance to oxidative stress are determinants of longevity in the longest-living rodent, the naked mole-rat. Proc Natl Acad Sci USA 2009;106:3059-64.
29. Bertell R. X ray exposure and premature aging. J Surg Oncol 1977;9:379-91.
30. Xu Y, Wu T, Jin Y, Fu Z. Effects of age and jet lag on d-galactose induced aging process. Biogerontology 2009;10:153-61.
31. Brown MK, Evans JL, Luo Y. Beneficial effects of natural antioxidants EGCG and alpha-lipoic acid on life span and age-dependent behavioral declines in Caenorhabditis elegans. Pharmacol Biochem Behav 2006;85:620-8.
32. Ralser M, Benjamin IJ. Reductive stress on life span extension in C. elegans. BMC Res Notes 2008;4:1-19.
33. Jafari M. Drosophila melanogaster as a model system for the evaluation of anti-aging compounds. Fly (Austin) 2010;4:253-7.
34. Miquel J, Lundgren PR, Bensch KG, Atlan H. Effects of temperature on the life span vitality and fine structure of Drosophila melanogaster. Mech Ageing Dev 1976;5:347-60.
35. Zheng J, Mutcherson R 2nd, Helfand SL. Calorie restriction delays lipid oxidative damage in Drosophila melanogaster. Aging Cell 2005;4:209-16.
36. Jeong K, Shin Y, Park S, Park J, Kim N, Um J et al. Ethanol extract of Scutellaria baicalensis Georgi prevents oxidative damage and neuroinflammation and memorial impairments in artificial senescense mice. J Biomed Sci 2011;18:14.
37. Li W, Nie S, Xie M, Yu Q, Chen Y, He M. Ganoderma atrum polysaccharide attenuates oxidative stress induced by d-galactose in mouse brain. Life Sci 2011;88:713-8.
38. Wei H, Li L, Song Q, Ai H, Chu J, Li W. Behavioural study of the d-galactose induced aging model in C57BL/6J mice. Behav Brain Res 2005;157:245-51.
39. Ho SC, Liu JH, Wu RY. Establishment of the mimetic aging effect in mice caused by d-galactose. Biogerontology 2003;4: 15-8.
40. Shen YX, Xu SY, Wei W, Sun XX, Yang J, Liu LH et al. Melatonin reduces memory changes and neural oxidative damage in mice treated with d-galactose. J Pineal Res 2002;32:173-8.
41. Song X, Bao M, Li D, Li YM. Advanced glycation in d-galactose induced mouse aging model. Mech Ageing Dev 1999;108:239-51.
42. Zhang X, An LJ, Bao YM, Wang JY, Jiang B. d-galactose administration induces memory loss and energy metabolism disturbance in mice: protective effects of catalpol. Food Chem Toxicol 2008;46:2888-94.
43. Hongxing Z, Nancai Y, Guofu H, Jianbo S, Yanxia W, Hanju H et al. Neuroprotective effects of purslane herb aquenous extracts against d-galactose induced neurotoxicity. Chem Biol Interact 2007;170:145-52.
44. Lu J, Zheng YL, Wu DM, Luo L, Sun DX, Shan Q. Ursolic acid ameliorates cognition deficits and attenuates oxidative damage in the brain of senescent mice induced by d-galactose. Biochem Pharmacol 2007;74:1078-90.
45. Aydin S, Atukeren P, Cakatay U, Uzun H, Altuǧ T. Gender-dependent oxidative variations in liver of aged rats. Biogerontology 2010;11:335-46.
46. Kayali R, Cakatay U, Uzun H, Genc H. Gender difference as regards myocardial protein oxidation in aged rats: male rats have increased oxidative protein damage. Biogerontology 2007;8: 653-61.
47. Guevara R, Santandreu FM, Valle A, Gianotti M, Oliver J, Roca P. Sex-dependent differences in aged rats brain mitochondrial function and oxidative stress. Free Radic Biol Med 2009;46:169-75.
48. Vina J, Lloret A. Why women have more Alzheimer's disease than men: gender and mitochondrial toxicity of amyloid beta-peptide. J Alzheimer's Dis 2010;2:527-33.
49. Kong W, Hu Y, Wang Q, Xu L, Wang Y, Han Y et al. Establishment of model with inner ear mimetic aging and mtDNA 4834bp deletion in rats. Lin Chuang Er Bi Yan Hou Ke Za Zhi 2006;20:888-90.
50. Xu XH, Zhao TQ. Effects of puerarin on d-galactose-induced memory deficits in mice. Acta Pharmacol Sin 2002;23: 587-90.
51. Capaillére-Blandin C, Gausson V, Descamps-Latscha B, Witko-Sarsat V. Biochemical and spectrophotometric significance of advanced oxidized protein products. Biochim Biophys Acta 2004;1689:91-102.
52. Mocsai A, Ruland J, Tybulewicz VL. The SYK tyrosine kinase: a crucial player in diverse biological functions. Nat Rev Immunol 2010;10:387-402.
53. Wolf F, Fasanella S, Tedesco B, Cavallini G, Donati A, Bergamini E et al. Peripheral lymphocyte 8-OHdG levels correlate with age-associated increase of tissue oxidative DNA damage in Sprague-Dawley rats. Protective effects of caloric restriction. Exp Gerontol 2005;40:181-8.
54. De Meyer T, Rietzschel ER, De Buyzere ML, Van Criekinge W, Bekaert S. Studying telomeres in a longitudinal population based study. Front Biosci 2008;13:2960-70.
55. Haripiya D, Sangeetha P, Konchana A, Balu M, Panneerselvam C. Modulation of age-associated oxidative DNA damage in rat brain cerebral cortex, striatum and hippocampus by L-carnitine. Exp Gerontol 2005;40:129-35.
56. Luxford C, Dean RT, Davies MJ. Radicals derived from histone hydroperoxides damage nucleobases in RNA and DNA. Chem Res Toxicol 2000;13:665-72.
57. Bobba A, Petragallo VA, Marra E, Atlante A. Alzheimer's proteins, oxidative stress and mitochondrial dysfunction interplay in a neuronal model of Alzheimer's Disease. Int J Alzheimers Dis 2010;2010:1-11.
58. Grune T, Merker K, Jung T, Sitte N, Davies KJ. Protein oxidation and degradation during postmitotic senescence. Free Radic Biol Med 2005;39:1208-15.
59. Çakatay U, Telci A, Kayali R, Tekeli F, Akçay T, Sivas A. Relation of oxidative protein damage and nitrotyrosine levels in the aging rat brain. Exp Gerontol 2001;36:221-9.