Computational modeling identifies key gene regulatory interactions underlying phenobarbital-mediated tumor promotion

Nucleic Acids Research

Volumn 42, Issue 7, 2014, Pages 4180-4195

  Luisier, Raphaëlle ^a   Unterberger, Elif B ^b   Goodman, Jay I ^c   Schwarz, Michael ^b   Moggs, Jonathan ^a   Terranova, Rémi ^a   Van Nimwegen, Erik ^d  

^a NOVARTIS PHARMA AG   (Switzerland)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c MICHIGAN STATE UNIVERSITY   (United States)

^d SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CONSTITUTIVE ANDROSTANE RECEPTOR; MEMBRANE PROTEIN; PHENOBARBITAL; PROTEIN ESR1; PROTEIN ZFP161; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR E2F; UNCLASSIFIED DRUG;

ANALYTICAL PARAMETERS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOMATION; BINDING SITE; CELL PROLIFERATION; CONTROLLED STUDY; GENE EXPRESSION; GENE INTERACTION; GENE REGULATORY NETWORK; GENETIC PROCEDURES; IN VIVO STUDY; LIVER CANCER; LIVER CARCINOGENESIS; LIVER CELL; MALE; MATHEMATICAL MODEL; MOTIF ACTIVITY RESPONSE ANALYSIS; MOUSE; MOUSE MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SINGULAR VALUE DECOMPOSITION; TOXICOGENETICS; TRANSCRIPTION REGULATION; TRANSCRIPTOMICS; TRANSGENIC MOUSE; TUMOR MICROENVIRONMENT; TUMOR PROMOTION;

ANIMALS; BETA CATENIN; BINDING SITES; CARCINOGENESIS; CELL PROLIFERATION; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE REGULATORY NETWORKS; LIVER; LIVER NEOPLASMS; MALE; MICE; NUCLEOTIDE MOTIFS; PHENOBARBITAL; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 84899026065     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkt1415     Document Type: Article

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