-
1
-
-
67649993396
-
Future of cancer incidence in the United States: Burdens upon an aging, changing nation
-
Smith BD, Smith GL, Hurria A, et al. Future of cancer incidence in the United States: burdens upon an aging, changing nation. J Clin Oncol. 2009;27(17):2758-2765.
-
(2009)
J Clin Oncol.
, vol.27
, Issue.17
, pp. 2758-2765
-
-
Smith, B.D.1
Smith, G.L.2
Hurria, A.3
-
2
-
-
84860223568
-
Annual report to the nation on the status of cancer 1975-2008, featuring cancers associated with excess weight and lack of sufficient physical activity
-
Eheman C, Henley SJ, Ballard-Barbash R, et al. Annual report to the nation on the status of cancer, 1975-2008, featuring cancers associated with excess weight and lack of sufficient physical activity. Cancer. 2012;118(9):2338-2366.
-
(2012)
Cancer.
, vol.118
, Issue.9
, pp. 2338-2366
-
-
Eheman, C.1
Henley, S.J.2
Ballard-Barbash, R.3
-
3
-
-
84863707351
-
Cancer treatment and survivorship statistics 2012
-
Siegel R, DeSantis C, Virgo K, et al. Cancer treatment and survivorship statistics, 2012. CA Cancer J Clin. 2012;62(4):220-241.
-
(2012)
CA Cancer J Clin.
, vol.62
, Issue.4
, pp. 220-241
-
-
Siegel, R.1
Desantis, C.2
Virgo, K.3
-
4
-
-
84870223860
-
Differential effects of radiotherapy on growth and endocrine function among acute leukemia survivors: A childhood cancer survivor study report
-
Chow EJ, Liu W, Srivastava K, et al. Differential effects of radiotherapy on growth and endocrine function among acute leukemia survivors: a childhood cancer survivor study report. Pediatr Blood Cancer. 2013;60(1):110-115.
-
(2013)
Pediatr Blood Cancer.
, vol.60
, Issue.1
, pp. 110-115
-
-
Chow, E.J.1
Liu, W.2
Srivastava, K.3
-
5
-
-
79951492419
-
Morbidity and mortality in long-term survivors of Hodgkin lymphoma: A report from the Childhood Cancer Survivor Study
-
Castellino SM, Geiger AM, Mertens AC, et al. Morbidity and mortality in long-term survivors of Hodgkin lymphoma: a report from the Childhood Cancer Survivor Study. Blood. 2011;117(6):1806-1816.
-
(2011)
Blood.
, vol.117
, Issue.6
, pp. 1806-1816
-
-
Castellino, S.M.1
Geiger, A.M.2
Mertens, A.C.3
-
6
-
-
84867598843
-
Neurocognitive function and CNS integrity in adult survivors of childhood hodgkin lymphoma
-
Krull KR, Sabin ND, Reddick WE, et al. Neurocognitive function and CNS integrity in adult survivors of childhood hodgkin lymphoma. J Clin Oncol. 2012;30(29):3618-3624.
-
(2012)
J Clin Oncol.
, vol.30
, Issue.29
, pp. 3618-3624
-
-
Krull, K.R.1
Sabin, N.D.2
Reddick, W.E.3
-
7
-
-
84856214155
-
Neuromuscular impairments in adult survivors of childhood acute lymphoblastic leukemia: Associations with physical performance and chemotherapy doses
-
Ness KK, Hudson MM, Pui CH, et al. Neuromuscular impairments in adult survivors of childhood acute lymphoblastic leukemia: associations with physical performance and chemotherapy doses. Cancer. 2012;118(3):828-838.
-
(2012)
Cancer.
, vol.118
, Issue.3
, pp. 828-838
-
-
Ness, K.K.1
Hudson, M.M.2
Pui, C.H.3
-
8
-
-
84869118138
-
Troublesome symptoms in cancer survivors: Fatigue, insomnia, neuropathy, and pain
-
Pachman DR, Barton DL, Swetz KM, et al. Troublesome symptoms in cancer survivors: fatigue, insomnia, neuropathy, and pain. J Clin Oncol. 2012;30(30):3687-3696.
-
(2012)
J Clin Oncol.
, vol.30
, Issue.30
, pp. 3687-3696
-
-
Pachman, D.R.1
Barton, D.L.2
Swetz, K.M.3
-
10
-
-
34548153747
-
How stem cells age and why this makes us grow old
-
Sharpless NE, DePinho RA. How stem cells age and why this makes us grow old. Nat Rev Mol Cell Biol. 2007;8(9):703-713.
-
(2007)
Nat Rev Mol Cell Biol.
, vol.8
, Issue.9
, pp. 703-713
-
-
Sharpless, N.E.1
Depinho, R.A.2
-
11
-
-
79951912532
-
Four faces of cellular senescence
-
Rodier F, Campisi J. Four faces of cellular senescence. J Cell Biol. 2011;192(4):547-556.
-
(2011)
J Cell Biol.
, vol.192
, Issue.4
, pp. 547-556
-
-
Rodier, F.1
Campisi, J.2
-
12
-
-
0030612349
-
Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging
-
Zindy F, Quelle DE, Roussel MF, et al. Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging. Oncogene. 1997;15(2):203-211.
-
(1997)
Oncogene.
, vol.15
, Issue.2
, pp. 203-211
-
-
Zindy, F.1
Quelle, D.E.2
Roussel, M.F.3
-
13
-
-
84900969225
-
Ink4a/Arf expression is a biomarker of aging
-
Krishnamurthy J, Torrice C, Ramsey MR, et al. Ink4a/Arf expression is a biomarker of aging. J Clin Invest. 2004;114(9):1299-1307.
-
(2004)
J Clin Invest.
, vol.114
, Issue.9
, pp. 1299-1307
-
-
Krishnamurthy, J.1
Torrice, C.2
Ramsey, M.R.3
-
14
-
-
67651180787
-
Expression of p16(INK4a) in peripheral blood T-cells is a biomarker of human aging
-
Liu Y, Sanoff HK, Cho H, et al. Expression of p16(INK4a) in peripheral blood T-cells is a biomarker of human aging. Aging Cell. 2009;8(4):439-448.
-
(2009)
Aging Cell.
, vol.8
, Issue.4
, pp. 439-448
-
-
Liu, Y.1
Sanoff, H.K.2
Cho, H.3
-
15
-
-
33749187810
-
P16(INK4a) induces an age-dependent decline in islet regenerative potential
-
Krishnamurthy J, Ramsey MR, Ligon KL, et al. p16(INK4a) induces an age-dependent decline in islet regenerative potential. Nature. 2006;443(7110):453-457.
-
(2006)
Nature.
, vol.443
, Issue.7110
, pp. 453-457
-
-
Krishnamurthy, J.1
Ramsey, M.R.2
Ligon, K.L.3
-
16
-
-
33749171885
-
Increasing p16(INK4a) expression decreases forebrain progenitors and neurogenesis during ageing
-
Molofsky AV, Slutsky SG, Joseph NM, et al. Increasing p16(INK4a) expression decreases forebrain progenitors and neurogenesis during ageing. Nature. 2006;443(7110):448-452.
-
(2006)
Nature.
, vol.443
, Issue.7110
, pp. 448-452
-
-
Molofsky, A.V.1
Slutsky, S.G.2
Joseph, N.M.3
-
17
-
-
33749172559
-
Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16(INK4a)
-
Janzen V, Forkert R, Fleming HE, et al. Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16(INK4a). Nature. 2006;443(7110):421-426.
-
(2006)
Nature.
, vol.443
, Issue.7110
, pp. 421-426
-
-
Janzen, V.1
Forkert, R.2
Fleming, H.E.3
-
18
-
-
79953086335
-
Expression of p16(INK4a) prevents cancer and promotes aging in lymphocytes
-
Liu Y, Johnson SM, Fedoriw Y, et al. Expression of p16(INK4a) prevents cancer and promotes aging in lymphocytes. Blood. 2011;117(12):3257-3267.
-
(2011)
Blood.
, vol.117
, Issue.12
, pp. 3257-3267
-
-
Liu, Y.1
Johnson, S.M.2
Fedoriw, Y.3
-
19
-
-
56549120340
-
Aging and cancer resistance in lymphoid progenitors are linked processes conferred by p16Ink4a and Arf
-
Signer RA, Montecino-Rodriguez E, Witte ON, et al. Aging and cancer resistance in lymphoid progenitors are linked processes conferred by p16Ink4a and Arf. Genes Dev. 2008;22(22):3115-3120.
-
(2008)
Genes Dev.
, vol.22
, Issue.22
, pp. 3115-3120
-
-
Signer, R.A.1
Montecino-Rodriguez, E.2
Witte, O.N.3
-
20
-
-
84866442827
-
Review: A meta-analysis of GWAS and age-associated diseases
-
Jeck WR, Siebold A P, Sharpless NE. Review: a meta-analysis of GWAS and age-associated diseases. Aging Cell. 2012;11(5):727-731.
-
(2012)
Aging Cell.
, vol.11
, Issue.5
, pp. 727-731
-
-
Jeck, W.R.1
Siebold, A.P.2
Sharpless, N.E.3
-
21
-
-
84862491835
-
Fibroblast growth factor-7 partially reverses murine thymocyte progenitor aging by repression of Ink4a
-
Berent-Maoz B, Montecino-Rodriguez E, Signer RA, et al. Fibroblast growth factor-7 partially reverses murine thymocyte progenitor aging by repression of Ink4a. Blood. 2012;119(24):5715-5721.
-
(2012)
Blood.
, vol.119
, Issue.24
, pp. 5715-5721
-
-
Berent-Maoz, B.1
Montecino-Rodriguez, E.2
Signer, R.A.3
-
22
-
-
80855138775
-
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
-
Baker DJ, Wijshake T, Tchkonia T, et al. Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders. Nature. 2011;479(7372):232- 236.
-
(2011)
Nature.
, vol.479
, Issue.7372
, pp. 232-236
-
-
Baker, D.J.1
Wijshake, T.2
Tchkonia, T.3
-
23
-
-
80054991835
-
PDGF signalling controls age-dependent proliferation in pancreatic beta-cells
-
Chen H, Gu X, Liu Y, et al. PDGF signalling controls age-dependent proliferation in pancreatic beta-cells. Nature. 2011;478(7369):349-355.
-
(2011)
Nature.
, vol.478
, Issue.7369
, pp. 349-355
-
-
Chen, H.1
Gu, X.2
Liu, Y.3
-
24
-
-
23844517498
-
Obesity, cigarette smoking, and telomere length in women
-
Valdes AM, Andrew T, Gardner J P, et al. Obesity, cigarette smoking, and telomere length in women. Lancet. 2005;366(9486):662-664.
-
(2005)
Lancet.
, vol.366
, Issue.9486
, pp. 662-664
-
-
Valdes, A.M.1
Andrew, T.2
Gardner, J.P.3
-
25
-
-
67651183852
-
The association between leukocyte telomere length and cigarette smoking, dietary and physical variables, and risk of prostate cancer
-
Mirabello L, Huang WY, Wong JY, et al. The association between leukocyte telomere length and cigarette smoking, dietary and physical variables, and risk of prostate cancer. Aging Cell. 2009;8(4):405-413.
-
(2009)
Aging Cell.
, vol.8
, Issue.4
, pp. 405-413
-
-
Mirabello, L.1
Huang, W.Y.2
Wong, J.Y.3
-
26
-
-
78049441699
-
Lifestyle impacts on the aging-associated expression of biomarkers of DNA damage and telomere dysfunction in human blood
-
Song Z, von Figura G, Liu Y, et al. Lifestyle impacts on the aging-associated expression of biomarkers of DNA damage and telomere dysfunction in human blood. Aging Cell. 2010;9(4):607-615.
-
(2010)
Aging Cell.
, vol.9
, Issue.4
, pp. 607-615
-
-
Song, Z.1
Von Figura, G.2
Liu, Y.3
-
27
-
-
77949881221
-
The senescence-associated secretory phenotype: The dark side of tumor suppression
-
Coppe J P, Desprez PY, Krtolica A, et al. The senescence-associated secretory phenotype: the dark side of tumor suppression. Annu Rev Pathol. 2010;5:99-118.
-
(2010)
Annu Rev Pathol.
, vol.5
, pp. 99-118
-
-
Coppe, J.P.1
Desprez, P.Y.2
Krtolica, A.3
-
28
-
-
15244348518
-
The origins of age-related proin-flammatory state
-
Ferrucci L, Corsi A, Lauretani F, et al. The origins of age-related proin-flammatory state. Blood. 2005;105(6):2294-2299.
-
(2005)
Blood.
, vol.105
, Issue.6
, pp. 2294-2299
-
-
Ferrucci, L.1
Corsi, A.2
Lauretani, F.3
-
29
-
-
1642316427
-
Inflammatory markers and physical performance in older persons: The InCHIANTI study
-
Cesari M, Penninx BW, Pahor M, et al. Inflammatory markers and physical performance in older persons: the InCHIANTI study. J Gerontol A Biol Sci Med Sci. 2004;59(3):242-248.
-
(2004)
J Gerontol A Biol Sci Med Sci.
, vol.59
, Issue.3
, pp. 242-248
-
-
Cesari, M.1
Penninx, B.W.2
Pahor, M.3
-
30
-
-
0034473259
-
Cross-sectional and prospective relationships of interleukin-6 and C-reactive protein with physical performance in elderly persons: MacArthur studies of successful aging
-
Taaffe DR, Harris TB, Ferrucci L, et al. Cross-sectional and prospective relationships of interleukin-6 and C-reactive protein with physical performance in elderly persons: MacArthur studies of successful aging. J Gerontol A Biol Sci Med Sci. 2000;55(12):M709-M715.
-
(2000)
J Gerontol A Biol Sci Med Sci.
, vol.55
, Issue.12
-
-
Taaffe, D.R.1
Harris, T.B.2
Ferrucci, L.3
-
31
-
-
79955973916
-
Inflammatory markers in population studies of aging
-
Singh T, Newman AB. Inflammatory markers in population studies of aging. Ageing Res Rev. 2011;10(3):319-329.
-
(2011)
Ageing Res Rev.
, vol.10
, Issue.3
, pp. 319-329
-
-
Singh, T.1
Newman, A.B.2
-
32
-
-
33745185337
-
Interleukin-6 in aging and chronic disease: A magnificent pathway
-
Maggio M, Guralnik JM, Longo DL, et al. Interleukin-6 in aging and chronic disease: a magnificent pathway. J Gerontol A Biol Sci Med Sci. 2006;61(6):575-584.
-
(2006)
J Gerontol A Biol Sci Med Sci.
, vol.61
, Issue.6
, pp. 575-584
-
-
Maggio, M.1
Guralnik, J.M.2
Longo, D.L.3
-
33
-
-
84866441992
-
Expression of p16(INK4a) as a biomarker of T-cell aging in HIV-infected patients prior to and during antiretroviral therapy
-
Nelson JA, Krishnamurthy J, Menezes P, et al. Expression of p16(INK4a) as a biomarker of T-cell aging in HIV-infected patients prior to and during antiretroviral therapy. Aging Cell. 2012;11(5):916-918
-
(2012)
Aging Cell.
, vol.11
, Issue.5
, pp. 916-918
-
-
Nelson, J.A.1
Krishnamurthy, J.2
Menezes, P.3
-
34
-
-
0003809054
-
-
American Joint Committee on Cancer (AJCC) C, Illinois New York: Springer-Verlag
-
American Joint Committee on Cancer (AJCC) C, Illinois. AJCC Cancer Staging Manual. 6th ed. New York: Springer-Verlag; 2002.
-
(2002)
AJCC Cancer Staging Manual. 6th Ed
-
-
-
35
-
-
84872569990
-
Monitoring tumorigen-esis and senescence in vivo with a p16(INK4a)-luciferase model
-
Burd CE, Sorrentino JA, Clark KS, et al. Monitoring tumorigen-esis and senescence in vivo with a p16(INK4a)-luciferase model. Cell.2013;152(1-2):340- 351.
-
(2013)
Cell
, vol.152
, Issue.1-2
, pp. 340-351
-
-
Burd, C.E.1
Sorrentino, J.A.2
Clark, K.S.3
-
36
-
-
18444374159
-
Hepatocyte telomere shortening and senescence are general markers of human liver cirrhosis
-
Wiemann SU, Satyanarayana A, Tsahuridu M, et al. Hepatocyte telomere shortening and senescence are general markers of human liver cirrhosis. FASEB J. 2002;16(9):935-942.
-
(2002)
FASEB J.
, vol.16
, Issue.9
, pp. 935-942
-
-
Wiemann, S.U.1
Satyanarayana, A.2
Tsahuridu, M.3
-
37
-
-
33644692330
-
Cellular senescence in aging primates
-
Herbig U, Ferreira M, Condel L, et al. Cellular senescence in aging primates. Science. 2006;311(5765):1257.
-
(2006)
Science.
, vol.311
, Issue.5765
, pp. 1257
-
-
Herbig, U.1
Ferreira, M.2
Condel, L.3
-
38
-
-
0037687355
-
Randomized trial of dose-dense versus conventionally scheduled and sequential versus concurrent combination chemotherapy as postoperative adjuvant treatment of node-positive primary breast cancer: First report of Intergroup Trial C9741/Cancer and Leukemia Group B Trial 9741
-
Citron ML, Berry DA, Cirrincione C, et al. Randomized trial of dose-dense versus conventionally scheduled and sequential versus concurrent combination chemotherapy as postoperative adjuvant treatment of node-positive primary breast cancer: first report of Intergroup Trial C9741/Cancer and Leukemia Group B Trial 9741. J Clin Oncol. 2003;21(8):1431-1439.
-
(2003)
J Clin Oncol.
, vol.21
, Issue.8
, pp. 1431-1439
-
-
Citron, M.L.1
Berry, D.A.2
Cirrincione, C.3
-
39
-
-
33749549246
-
Secretion of vascular endothelial growth factor by primary human fibroblasts at senescence
-
Coppe J P, Kauser K, Campisi J, et al. Secretion of vascular endothelial growth factor by primary human fibroblasts at senescence. J Biol Chem. 2006;281(40):29568-29574.
-
(2006)
J Biol Chem.
, vol.281
, Issue.40
, pp. 29568-29574
-
-
Coppe, J.P.1
Kauser, K.2
Campisi, J.3
-
40
-
-
0032589106
-
Immunohistochemical survey of p16INK4A expression in normal human adult and infant tissues
-
Nielsen G P, Stemmer-Rachamimov AO, Shaw J, et al. Immunohistochemical survey of p16INK4A expression in normal human adult and infant tissues. Lab Invest. 1999;79(9):1137-1143.
-
(1999)
Lab Invest.
, vol.79
, Issue.9
, pp. 1137-1143
-
-
Nielsen, G.P.1
Stemmer-Rachamimov, A.O.2
Shaw, J.3
-
41
-
-
84873262839
-
A systematic review of leukocyte telomere length and age in adults
-
Muezzinler A, Zaineddin AK, Brenner H. A systematic review of leukocyte telomere length and age in adults. Ageing Res Rev. 2013;12(2):509-519.
-
(2013)
Ageing Res Rev.
, vol.12
, Issue.2
, pp. 509-519
-
-
Muezzinler, A.1
Zaineddin, A.K.2
Brenner, H.3
-
42
-
-
0027973679
-
Interleukin-6 and selected plasma proteins in healthy persons of different ages
-
Hager K, Machein U, Krieger S, et al. Interleukin-6 and selected plasma proteins in healthy persons of different ages. Neurobiol Aging. 1994;15(6):771-772.
-
(1994)
Neurobiol Aging.
, vol.15
, Issue.6
, pp. 771-772
-
-
Hager, K.1
Machein, U.2
Krieger, S.3
-
43
-
-
68949088900
-
Telomere dynamics in aging: Much ado about nothing?
-
Longo DL. Telomere dynamics in aging: much ado about nothing? J Gerontol A Biol Sci Med Sci. 2009;64(9):963-964.
-
(2009)
J Gerontol A Biol Sci Med Sci.
, vol.64
, Issue.9
, pp. 963-964
-
-
Longo, D.L.1
-
44
-
-
0035906808
-
Telomere length in breast cancer patients before and after chemotherapy with or without stem cell transplantation
-
Schroder CP, Wisman GB, de Jong S, et al. Telomere length in breast cancer patients before and after chemotherapy with or without stem cell transplantation. Br J Cancer. 2001;84(10):1348-1353.
-
(2001)
Br J Cancer.
, vol.84
, Issue.10
, pp. 1348-1353
-
-
Schroder, C.P.1
Wisman, G.B.2
De Jong, S.3
-
45
-
-
84869133829
-
A phase I/II trial of intensity modulated radiation (IMRT) dose escalation with concurrent fixed-dose rate gemcitabine (FDR-G) in patients with unresectable pancreatic cancer
-
Ben-Josef E, Schipper M, Francis IR, et al. A phase I/II trial of intensity modulated radiation (IMRT) dose escalation with concurrent fixed-dose rate gemcitabine (FDR-G) in patients with unresectable pancreatic cancer. Int J Radiat Oncol Biol Phys. 2012;84(5):1166-1171.
-
(2012)
Int J Radiat Oncol Biol Phys.
, vol.84
, Issue.5
, pp. 1166-1171
-
-
Ben-Josef, E.1
Schipper, M.2
Francis, I.R.3
-
46
-
-
0037278402
-
Granulocyte colony-stimulating factor administration upregulates telomerase activity in CD34+ haematopoietic cells and may prevent telomere attrition after chemotherapy
-
Szyper-Kravitz M, Uziel O, Shapiro H, et al. Granulocyte colony-stimulating factor administration upregulates telomerase activity in CD34+ haematopoietic cells and may prevent telomere attrition after chemotherapy. Br J Haematol. 2003;120(2):329-336.
-
(2003)
Br J Haematol.
, vol.120
, Issue.2
, pp. 329-336
-
-
Szyper-Kravitz, M.1
Uziel, O.2
Shapiro, H.3
-
47
-
-
0030920228
-
Telomerase regulation, cell cycle, and telomere stability in primitive hematopoietic cells
-
Engelhardt M, Kumar R, Albanell J, et al. Telomerase regulation, cell cycle, and telomere stability in primitive hematopoietic cells. Blood. 1997;90(1):182-193.
-
(1997)
Blood.
, vol.90
, Issue.1
, pp. 182-193
-
-
Engelhardt, M.1
Kumar, R.2
Albanell, J.3
-
48
-
-
0038277105
-
Tumor cell senescence in cancer treatment
-
Roninson IB. Tumor cell senescence in cancer treatment. Cancer Res. 2003;63(11):2705-2715.
-
(2003)
Cancer Res.
, vol.63
, Issue.11
, pp. 2705-2715
-
-
Roninson, I.B.1
-
49
-
-
0034051068
-
Age-associated increased interleukin-6 gene expression, late-life diseases, and frailty
-
Ershler WB, Keller ET. Age-associated increased interleukin-6 gene expression, late-life diseases, and frailty. Annu Rev Med. 2000;51:245-270.
-
(2000)
Annu Rev Med.
, vol.51
, pp. 245-270
-
-
Ershler, W.B.1
Keller, E.T.2
-
50
-
-
34250007142
-
Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age
-
Rossi DJ, Bryder D, Seita J, et al. Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age. Nature. 2007;447(7145):725-729.
-
(2007)
Nature.
, vol.447
, Issue.7145
, pp. 725-729
-
-
Rossi, D.J.1
Bryder, D.2
Seita, J.3
-
51
-
-
84856636292
-
Comparisons between different polychemotherapy regimens for early breast cancer: Meta-analyses of long-term outcome among 100, 000 women in 123 randomised trials
-
Early Breast Cancer Trialists' Collaborative Group
-
Early Breast Cancer Trialists' Collaborative Group, Peto R, Davies C, et al. Comparisons between different polychemotherapy regimens for early breast cancer: meta-analyses of long-term outcome among 100, 000 women in 123 randomised trials. Lancet. 2012;379(9814):432-444.
-
(2012)
Lancet.
, vol.379
, Issue.9814
, pp. 432-444
-
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Peto, R.1
Davies, C.2
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