Past strategies and future directions for identifying AMP-activated protein kinase (AMPK) modulators

Pharmacology and Therapeutics

Volumn 143, Issue 1, 2014, Pages 111-118

  Sinnett, Sarah E ^a   Brenman, Jay E ^a,b  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

AMPK; Dephosphorylation inhibition; Drug discovery; High throughput screening; Nucleotide analogs; Regulatory fragment

Indexed keywords

ADENOSINE PHOSPHATE; HOLOENZYME; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; NUCLEOTIDE; PROTEIN KINASE INHIBITOR; ISOENZYME;

ARTICLE; ENZYME STRUCTURE; HUMAN; NEOPLASM; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TRANSLATIONAL RESEARCH; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMISTRY; DRUG DEVELOPMENT; PHYSIOLOGY;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; DRUG DISCOVERY; HOLOENZYMES; HUMANS; ISOENZYMES; PROTEIN KINASE INHIBITORS;

EID: 84898902372     PISSN: 01637258     EISSN: 1879016X     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2014.02.008     Document Type: Review

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