-
1
-
-
25844490095
-
Epidemiology of psoriatic arthritis in the population of the United States
-
Gelfand JM, Gladman DD, Mease PJ, et al. Epidemiology of psoriatic arthritis in the population of the United States. J Am Acad Dermatol 2005;53(4):573
-
(2005)
J Am Acad Dermatol
, vol.53
, Issue.4
, pp. 573
-
-
Gelfand, J.M.1
Gladman, D.D.2
Mease, P.J.3
-
2
-
-
0031802067
-
Mortality studies in psoriatic arthritis: Results from a single outpatient center
-
Gladman DD, Farewell VT, Wong K, Husted J. Mortality studies in psoriatic arthritis: results from a single outpatient center. II. Prognostic indicators for death. Arthritis Rheum 1998;41(6): 1103-10
-
(1998)
II. Prognostic Indicators for Death. Arthritis Rheum
, vol.41
, Issue.6
, pp. 1103-1110
-
-
Gladman, D.D.1
Farewell, V.T.2
Wong, K.3
Husted, J.4
-
3
-
-
0035013738
-
Comparison of radiological severity in psoriatic arthritis and rheumatoid arthritis
-
Rahman P, Nguyen E, Cheung C, et al. Comparison of radiological severity in psoriatic arthritis and rheumatoid arthritis. J Rheumatol 2001;28(5): 1041-4
-
(2001)
J Rheumatol
, vol.28
, Issue.5
, pp. 1041-1044
-
-
Rahman, P.1
Nguyen, E.2
Cheung, C.3
-
4
-
-
80053921600
-
Management of psoriatic arthritis from the view of the dermatologist
-
Chang CA, Gottlieb AB, Lizzul PF. Management of psoriatic arthritis from the view of the dermatologist. Nat Rev Rheumatol 2011;7(10):588-98
-
(2011)
Nat Rev Rheumatol
, vol.7
, Issue.10
, pp. 588-598
-
-
Chang, C.A.1
Gottlieb, A.B.2
Lizzul, P.F.3
-
5
-
-
12144281223
-
Psoriasis: Emerging therapeutic strategies
-
Gottlieb AB. Psoriasis: emerging therapeutic strategies. Nat Rev Drug Discov 2005;4(1): 19-34
-
(2005)
Nat Rev Drug Discov
, vol.4
, Issue.1
, pp. 19-34
-
-
Gottlieb, A.B.1
-
6
-
-
33644994362
-
Quality-of-life issues in psoriasis and psoriatic arthritis: Outcome measures and therapies from a dermatological perspective
-
Mease PJ, Menter MA. Quality-of-life issues in psoriasis and psoriatic arthritis: outcome measures and therapies from a dermatological perspective. J Am Acad Dermatol 2006;54(4):685-704
-
(2006)
J Am Acad Dermatol
, vol.54
, Issue.4
, pp. 685-704
-
-
Mease, P.J.1
Menter, M.A.2
-
7
-
-
84875864504
-
The IL-23/T17 pathogenic axis in psoriasis is amplified by keratinocyte responses
-
Lowes MA, Russell CB, Martin DA, et al. The IL-23/T17 pathogenic axis in psoriasis is amplified by keratinocyte responses. Trends Immunol 2013;34(4):174-81
-
(2013)
Trends Immunol
, vol.34
, Issue.4
, pp. 174-181
-
-
Lowes, M.A.1
Russell, C.B.2
Martin, D.A.3
-
8
-
-
77952746286
-
Identification of TNF-related apoptosis-inducing ligand and other molecules that distinguish inflammatory from resident dendritic cells in patients with psoriasis
-
e1269
-
Zaba LC, Fuentes-Duculan J, Eungdamrong NJ, et al. Identification of TNF-related apoptosis-inducing ligand and other molecules that distinguish inflammatory from resident dendritic cells in patients with psoriasis. J Allergy Clin Immunol 2010;125(6):1261-8; e1269
-
(2010)
J Allergy Clin Immunol
, vol.125
, Issue.6
, pp. 1261-1268
-
-
Zaba, L.C.1
Fuentes-Duculan, J.2
Eungdamrong, N.J.3
-
9
-
-
83555174764
-
IL-17 receptor and its functional significance in psoriatic arthritis
-
Raychaudhuri SP, Raychaudhuri SK, Genovese MC. IL-17 receptor and its functional significance in psoriatic arthritis. Mol Cell Biochem 2012;359(1-2):419-29
-
(2012)
Mol Cell Biochem
, vol.359
, Issue.1-2
, pp. 419-429
-
-
Raychaudhuri, S.P.1
Raychaudhuri, S.K.2
Genovese, M.C.3
-
10
-
-
84865373941
-
Efficacy of apremilast in the treatment of moderate to severe psoriasis: A randomised controlled trial
-
Papp K, Cather JC, Rosoph L, et al. Efficacy of apremilast in the treatment of moderate to severe psoriasis: a randomised controlled trial. Lancet 2012;380(9843): 738-46
-
(2012)
Lancet
, vol.380
, Issue.9843
, pp. 738-746
-
-
Papp, K.1
Cather, J.C.2
Rosoph, L.3
-
11
-
-
82755197725
-
Do patients with psoriatic arthritis who present early fare better than those presenting later in the disease?
-
Gladman DD, Thavaneswaran A, Chandran V, Cook RJ. Do patients with psoriatic arthritis who present early fare better than those presenting later in the disease? Ann Rheum Dis 2011;70(12): 2152-4
-
(2011)
Ann Rheum Dis
, vol.70
, Issue.12
, pp. 2152-2154
-
-
Gladman, D.D.1
Thavaneswaran, A.2
Chandran, V.3
Cook, R.J.4
-
12
-
-
14244269340
-
Psoriatic arthritis therapy: NSAIDs and traditional DMARDs
-
Nash P, Clegg DO. Psoriatic arthritis therapy: NSAIDs and traditional DMARDs. Ann Rheum Dis 2005;64(Suppl 2):ii74-7
-
(2005)
Ann Rheum Dis
, vol.64
, Issue.SUPPL. 2
-
-
Nash, P.1
Clegg, D.O.2
-
13
-
-
0035065835
-
The role of NSAIDs in psoriatic arthritis: Evidence from a controlled study with nimesulide
-
Sarzi-Puttini P, Santandrea S, Boccassini L, et al. The role of NSAIDs in psoriatic arthritis: evidence from a controlled study with nimesulide. Clin Exp Rheumatol 2001; 19(1 Suppl 22):S17-20
-
(2001)
Clin Exp Rheumatol
, vol.19
, Issue.1 SUPPL. 22
-
-
Sarzi-Puttini, P.1
Santandrea, S.2
Boccassini, L.3
-
14
-
-
41949094481
-
Guidelines of care for the management of psoriasis and psoriatic arthritis: Section 1. Overview of psoriasis and guidelines of care for the treatment of psoriasis with biologics
-
Menter A, Gottlieb A, Feldman SR, et al. Guidelines of care for the management of psoriasis and psoriatic arthritis: section 1. Overview of psoriasis and guidelines of care for the treatment of psoriasis with biologics. J Am Acad Dermatol 2008;58(5):826-50
-
(2008)
J Am Acad Dermatol
, vol.58
, Issue.5
, pp. 826-850
-
-
Menter, A.1
Gottlieb, A.2
Feldman, S.R.3
-
15
-
-
69949125952
-
Treatment recommendations for psoriatic arthritis
-
Ritchlin CT, Kavanaugh A, Gladman DD, et al. Treatment recommendations for psoriatic arthritis. Ann Rheum Dis 2009; 68(9):1387-94
-
(2009)
Ann Rheum Dis
, vol.68
, Issue.9
, pp. 1387-1394
-
-
Ritchlin, C.T.1
Kavanaugh, A.2
Gladman, D.D.3
-
16
-
-
0030905089
-
Highly increased levels of tumor necrosis factor-alpha and other proinflammatory cytokines in psoriatic arthritis synovial fluid
-
Partsch G, Steiner G, Leeb BF, et al. Highly increased levels of tumor necrosis factor-alpha and other proinflammatory cytokines in psoriatic arthritis synovial fluid. J Rheumatol 1997;24(3):518-23
-
(1997)
J Rheumatol
, vol.24
, Issue.3
, pp. 518-523
-
-
Partsch, G.1
Steiner, G.2
Leeb, B.F.3
-
17
-
-
84875643445
-
New developments in the management of psoriasis and psoriatic arthritis: A focus on apremilast
-
Palfreeman AC, McNamee KE, McCann FE. New developments in the management of psoriasis and psoriatic arthritis: a focus on apremilast. Drug Des Devel Ther 2013;7:201-10
-
(2013)
Drug des Devel Ther
, vol.7
, pp. 201-210
-
-
Palfreeman, A.C.1
McNamee, K.E.2
McCann, F.E.3
-
18
-
-
2642558895
-
Efficacy and safety of leflunomide in the treatment of psoriatic arthritis and psoriasis: A multinational, double-blind, randomized, placebo-controlled clinical trial
-
Kaltwasser JP, Nash P, Gladman D, et al. Efficacy and safety of leflunomide in the treatment of psoriatic arthritis and psoriasis: a multinational, double-blind, randomized, placebo-controlled clinical trial. Arthritis Rheum 2004;50(6):1939-50
-
(2004)
Arthritis Rheum
, vol.50
, Issue.6
, pp. 1939-1950
-
-
Kaltwasser, J.P.1
Nash, P.2
Gladman, D.3
-
19
-
-
70349907640
-
Criteria, frequency, and duration of clinical remission in psoriatic arthritis patients with peripheral involvement requiring second-line drugs
-
Cantini F, Niccoli L, Nannini C, et al. Criteria, frequency, and duration of clinical remission in psoriatic arthritis patients with peripheral involvement requiring second-line drugs. J Rheumatol Suppl 2009;83:78-80
-
(2009)
J Rheumatol Suppl
, vol.83
, pp. 78-80
-
-
Cantini, F.1
Niccoli, L.2
Nannini, C.3
-
21
-
-
84891740105
-
Efficacy and safety of secukinumab, a fully human anti-interleukin-17A monoclonal antibody, in patients with moderate-to-severe psoriatic arthritis: A 24-week, randomised, double-blind, placebo-controlled, phase II proof-of-concept trial
-
McInnes IB, Sieper J, Braun J, et al. Efficacy and safety of secukinumab, a fully human anti-interleukin-17A monoclonal antibody, in patients with moderate-to-severe psoriatic arthritis: a 24-week, randomised, double-blind, placebo-controlled, phase II proof-of-concept trial. Ann Rheum Dis 2014;73(2):349-56
-
(2014)
Ann Rheum Dis
, vol.73
, Issue.2
, pp. 349-356
-
-
McInnes, I.B.1
Sieper, J.2
Braun, J.3
-
22
-
-
67649873326
-
Golimumab: In the treatment of rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis
-
Oldfield V, Plosker GL. Golimumab: in the treatment of rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis. BioDrug 2009;23(2):125-35
-
(2009)
BioDrug
, vol.23
, Issue.2
, pp. 125-135
-
-
Oldfield, V.1
Plosker, G.L.2
-
23
-
-
67650216399
-
Induction and exacerbation of psoriasis with TNF-blockade therapy: A review and analysis of 127 cases
-
Ko JM, Gottlieb AB, Kerbleski JF. Induction and exacerbation of psoriasis with TNF-blockade therapy: a review and analysis of 127 cases. J Dermatolog Treat 2009;20(2):100-8
-
(2009)
J Dermatolog Treat
, vol.20
, Issue.2
, pp. 100-108
-
-
Ko, J.M.1
Gottlieb, A.B.2
Kerbleski, J.F.3
-
24
-
-
43049115714
-
Exacerbation of psoriatic skin lesions in a patient with psoriatic arthritis receiving adalimumab
-
Borras-Blasco J, Gracia-Perez A, Nunez-Cornejo C, et al. Exacerbation of psoriatic skin lesions in a patient with psoriatic arthritis receiving adalimumab. J Clin Pharm Ther 2008;33(3):321-5
-
(2008)
J Clin Pharm Ther
, vol.33
, Issue.3
, pp. 321-325
-
-
Borras-Blasco, J.1
Gracia-Perez, A.2
Nunez-Cornejo, C.3
-
25
-
-
76749103918
-
Onset of palmoplantar pustular psoriasis while on adalimumab for psoriatic arthritis: A 'class effect' of TNF-alpha antagonists or simply an anti-psoriatic treatment adverse reaction?
-
Rallis E, Korfitis C, Stavropoulou E, Papaconstantis M. Onset of palmoplantar pustular psoriasis while on adalimumab for psoriatic arthritis: a 'class effect' of TNF-alpha antagonists or simply an anti-psoriatic treatment adverse reaction? J Dermatolog Treat 2010;21(1):3-5
-
(2010)
J Dermatolog Treat
, vol.21
, Issue.1
, pp. 3-5
-
-
Rallis, E.1
Korfitis, C.2
Stavropoulou, E.3
Papaconstantis, M.4
-
26
-
-
57549092371
-
Anti-cyclic citrullinated peptide antibodies and IL-23p19 in psoriatic arthritis
-
Shibata S, Tada Y, Komine M, et al. Anti-cyclic citrullinated peptide antibodies and IL-23p19 in psoriatic arthritis. J Dermatolog Sci 2009;53(1):34-9
-
(2009)
J Dermatolog Sci
, vol.53
, Issue.1
, pp. 34-39
-
-
Shibata, S.1
Tada, Y.2
Komine, M.3
-
27
-
-
57349093812
-
Investigation of association of the IL12B and IL23R genes with psoriatic arthritis
-
Filer C, Ho P, Smith RL, et al. Investigation of association of the IL12B and IL23R genes with psoriatic arthritis. Arthritis Rheum 2008;58(12): 3705-9
-
(2008)
Arthritis Rheum
, vol.58
, Issue.12
, pp. 3705-3709
-
-
Filer, C.1
Ho, P.2
Smith, R.L.3
-
28
-
-
0031885819
-
Blockade of IL-12 during the induction of collagen-induced arthritis (CIA) markedly attenuates the severity of the arthritis
-
Malfait AM, Butler DM, Presky DH, et al. Blockade of IL-12 during the induction of collagen-induced arthritis (CIA) markedly attenuates the severity of the arthritis. Clin Exp Immunol 1998;111(2):377-83
-
(1998)
Clin Exp Immunol
, vol.111
, Issue.2
, pp. 377-383
-
-
Malfait, A.M.1
Butler, D.M.2
Presky, D.H.3
-
29
-
-
0344585384
-
Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice
-
Nakae S, Nambu A, Sudo K, Iwakura Y. Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice. J Immunol 2003;171(11):6173-7
-
(2003)
J Immunol
, vol.171
, Issue.11
, pp. 6173-6177
-
-
Nakae, S.1
Nambu, A.2
Sudo, K.3
Iwakura, Y.4
-
30
-
-
33751521013
-
Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction
-
Sato K, Suematsu A, Okamoto K, et al. Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction. J Exp Med 2006;203(12): 2673-82
-
(2006)
J Exp Med
, vol.203
, Issue.12
, pp. 2673-2682
-
-
Sato, K.1
Suematsu, A.2
Okamoto, K.3
-
31
-
-
60249084148
-
Ustekinumab, a human interleukin 12/ 23 monoclonal antibody, for psoriatic arthritis: Randomised, double-blind, placebo-controlled, crossover trial
-
Gottlieb A, Menter A, Mendelsohn A, et al. Ustekinumab, a human interleukin 12/ 23 monoclonal antibody, for psoriatic arthritis: randomised, double-blind, placebo-controlled, crossover trial. Lancet 2009;373(9664):633-40
-
(2009)
Lancet
, vol.373
, Issue.9664
, pp. 633-640
-
-
Gottlieb, A.1
Menter, A.2
Mendelsohn, A.3
-
32
-
-
84867424597
-
Comparative efficacy of biologics in psoriasis: A review
-
Kim IH, West CE, Kwatra SG, et al. Comparative efficacy of biologics in psoriasis: a review. Am J Clin Dermatol 2012;13(6):365-74
-
(2012)
Am J Clin Dermatol
, vol.13
, Issue.6
, pp. 365-374
-
-
Kim, I.H.1
West, C.E.2
Kwatra, S.G.3
-
33
-
-
84887442186
-
Ustekinumab in the treatment of psoriatic arthritis: Latest findings and clinical potential
-
Gottlieb A, Narang K. Ustekinumab in the treatment of psoriatic arthritis: latest findings and clinical potential. Ther Adv Musculoskelet Dis 2013;5(5):277-85
-
(2013)
Ther Adv Musculoskelet Dis
, vol.5
, Issue.5
, pp. 277-285
-
-
Gottlieb, A.1
Narang, K.2
-
34
-
-
84883134297
-
Efficacy and safety of ustekinumab in patients with active psoriatic arthritis: 1 year results of the phase 3, multicentre, double-blind, placebo-controlled PSUMMIT 1 trial
-
McInnes IB, Kavanaugh A, Gottlieb AB, et al. Efficacy and safety of ustekinumab in patients with active psoriatic arthritis: 1 year results of the phase 3, multicentre, double-blind, placebo-controlled PSUMMIT 1 trial. Lancet 2013;382(9894): 780-9
-
(2013)
Lancet
, vol.382
, Issue.9894
, pp. 780-789
-
-
McInnes, I.B.1
Kavanaugh, A.2
Gottlieb, A.B.3
-
35
-
-
84898917765
-
-
American College of Rheumatology/ ARHP Annual Meeting; 26-30 October 2013; San Diego, CA, USA
-
Ritchlin CM, Iain B, Kavanaugh A, et al. Maintenance of efficacy and safety of ustekinumab in patients with active psoriatic arthritis despite prior conventional nonbiologic and anti-TNF biologic therapy: 1 year results of a phase 3, multicenter, double-blind, placebo-controlled trial. 2013 American College of Rheumatology/ ARHP Annual Meeting; 26-30 October 2013; San Diego, CA, USA
-
(2013)
Maintenance of Efficacy and Safety of Ustekinumab in Patients with Active Psoriatic Arthritis Despite Prior Conventional Nonbiologic and Anti-TNF Biologic Therapy: 1 Year Results of A Phase 3, Multicenter, Double-blind, Placebo-controlled Trial
-
-
Ritchlin, C.M.1
Iain, B.2
Kavanaugh, A.3
-
36
-
-
84892170359
-
Ustekinumab associated with flares of psoriatic arthritis
-
Stamell EF, Kutner A, Viola K, et al. Ustekinumab associated with flares of psoriatic arthritis. JAMA Dermatol 2013; 149(12):1410-13
-
(2013)
JAMA Dermatol
, vol.149
, Issue.12
, pp. 1410-1413
-
-
Stamell, E.F.1
Kutner, A.2
Viola, K.3
-
37
-
-
84892161934
-
Selection of therapies in patients with psoriasis and psoriatic arthritis
-
Stevenson ML, Markowitz O. Selection of therapies in patients with psoriasis and psoriatic arthritis. Psoriasis Forum 2011;17: 144-7
-
(2011)
Psoriasis Forum
, vol.17
, pp. 144-147
-
-
Stevenson, M.L.1
Markowitz, O.2
-
38
-
-
84876370997
-
Major cardiovascular events associated with anti-IL 12/23 agents: A tale of two meta-analyses
-
Dommasch ED, Troxel AB, Gelfand JM. Major cardiovascular events associated with anti-IL 12/23 agents: a tale of two meta-analyses. J Am Acad Dermatol 2013; 68(5):863-5
-
(2013)
J Am Acad Dermatol
, vol.68
, Issue.5
, pp. 863-865
-
-
Dommasch, E.D.1
Troxel, A.B.2
Gelfand, J.M.3
-
40
-
-
79960208264
-
Psoriasis is associated with clinically significant cardiovascular risk: A Danish nationwide cohort study
-
Ahlehoff O, Gislason GH, Charlot M, et al. Psoriasis is associated with clinically significant cardiovascular risk: a Danish nationwide cohort study. J Intern Med 2011;270(2):147-57
-
(2011)
J Intern Med
, vol.270
, Issue.2
, pp. 147-157
-
-
Ahlehoff, O.1
Gislason, G.H.2
Charlot, M.3
-
41
-
-
80052074383
-
Association between biologic therapies for chronic plaque psoriasis and cardiovascular events: A meta-analysis of randomized controlled trials
-
Ryan C, Leonardi CL, Krueger JG, et al. Association between biologic therapies for chronic plaque psoriasis and cardiovascular events: a meta-analysis of randomized controlled trials. JAMA 2011;306(8):864-71
-
(2011)
JAMA
, vol.306
, Issue.8
, pp. 864-871
-
-
Ryan, C.1
Leonardi, C.L.2
Krueger, J.G.3
-
42
-
-
84876141103
-
Re-evaluation of the risk for major adverse cardiovascular events in patients treated with anti-IL-12/23 biological agents for chronic plaque psoriasis: A meta-analysis of randomized controlled trials
-
Tzellos T, Kyrgidis A, Zouboulis CC. Re-evaluation of the risk for major adverse cardiovascular events in patients treated with anti-IL-12/23 biological agents for chronic plaque psoriasis: a meta-analysis of randomized controlled trials. J Eur Acad Dermatol Venereol 2013;27(5):622-7
-
(2013)
J Eur Acad Dermatol Venereol
, vol.27
, Issue.5
, pp. 622-627
-
-
Tzellos, T.1
Kyrgidis, A.2
Zouboulis, C.C.3
-
43
-
-
84888205088
-
Long-term efficacy of ustekinumab in patients with moderate-to-severe psoriasis treated for up to 5 years in the PHOENIX 1 study
-
Kimball AB, Papp KA, Wasfi Y, et al. Long-term efficacy of ustekinumab in patients with moderate-to-severe psoriasis treated for up to 5 years in the PHOENIX 1 study. J Eur Acad Dermatol Venereol 2013;27(12):1535-45
-
(2013)
J Eur Acad Dermatol Venereol
, vol.27
, Issue.12
, pp. 1535-1545
-
-
Kimball, A.B.1
Papp, K.A.2
Wasfi, Y.3
-
44
-
-
0038603010
-
Progression of peripheral joint disease in psoriatic arthritis: A 5-yr prospective study
-
McHugh NJ, Balachrishnan C, Jones SM. Progression of peripheral joint disease in psoriatic arthritis: a 5-yr prospective study. Rheumatology (Oxford, England) 2003; 42(6):778-83
-
(2003)
Rheumatology (Oxford, England)
, vol.42
, Issue.6
, pp. 778-783
-
-
McHugh, N.J.1
Balachrishnan, C.2
Jones, S.M.3
-
45
-
-
54249130813
-
Th17 cytokines interleukin (IL)- 17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways
-
Nograles KE, Zaba LC, Guttman-Yassky E, et al. Th17 cytokines interleukin (IL)- 17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways. Br J Dermatol 2008;159(5): 1092-102
-
(2008)
Br J Dermatol
, vol.159
, Issue.5
, pp. 1092-1102
-
-
Nograles, K.E.1
Zaba, L.C.2
Guttman-Yassky, E.3
-
46
-
-
84858244873
-
Current investigational drugs in psoriasis
-
Ryan C, Abramson A, Patel M, Menter A. Current investigational drugs in psoriasis. Expert Opin Investig Drugs 2012;21(4): 473-87
-
(2012)
Expert Opin Investig Drugs
, vol.21
, Issue.4
, pp. 473-487
-
-
Ryan, C.1
Abramson, A.2
Patel, M.3
Menter, A.4
-
47
-
-
84859017988
-
Brodalumab, an anti-interleukin-17-receptor antibody for psoriasis
-
Papp KA, Leonardi C, Menter A, et al. Brodalumab, an anti-interleukin-17- receptor antibody for psoriasis. N Engl J Med 2012; 366(13):1181-9
-
(2012)
N Engl J Med
, vol.366
, Issue.13
, pp. 1181-1189
-
-
Papp, K.A.1
Leonardi, C.2
Menter, A.3
-
48
-
-
84859073115
-
Anti-interleukin-17 monoclonal antibody ixekizumab in chronic plaque psoriasis
-
Leonardi C, Matheson R, Zachariae C, et al. Anti-interleukin-17 monoclonal antibody ixekizumab in chronic plaque psoriasis. N Engl J Med 2012;366(13): 1190-9
-
(2012)
N Engl J Med
, vol.366
, Issue.13
, pp. 1190-1199
-
-
Leonardi, C.1
Matheson, R.2
Zachariae, C.3
-
49
-
-
84898908987
-
-
Skin & Allergy News. Available from [Last accessed 12 July 2013]
-
Worcester S. Psoriasis drug MK-3222 progresses through pipeline. Skin & Allergy News 2013. Available from: www. skinandallergynews.com/news/ conferencenews/ american-academy-of-dermatologyannual- meeting-2013/single- article/psoriasisdrug- mk-3222-progresses-through-pipeline/ eab1780ca1924cf44d735207b8823054.html [Last accessed 12 July 2013]
-
(2013)
Psoriasis Drug MK-3222 Progresses Through Pipeline
-
-
Worcester, S.1
-
52
-
-
73249116548
-
The Th17 cytokine IL-22 induces IL-20 production in keratinocytes: A novel immunological cascade with potential relevance in psoriasis
-
Wolk K, Witte E, Warszawska K, et al. The Th17 cytokine IL-22 induces IL-20 production in keratinocytes: a novel immunological cascade with potential relevance in psoriasis. Eur J Immunol 2009; 39(12):3570-81
-
(2009)
Eur J Immunol
, vol.39
, Issue.12
, pp. 3570-3581
-
-
Wolk, K.1
Witte, E.2
Warszawska, K.3
-
53
-
-
33846906224
-
Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis
-
Zheng Y, Danilenko DM, Valdez P, et al. Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis. Nature 2007;445(7128):648-51
-
(2007)
Nature
, vol.445
, Issue.7128
, pp. 648-651
-
-
Zheng, Y.1
Danilenko, D.M.2
Valdez, P.3
-
54
-
-
80052265685
-
Reversal of atopic dermatitis with narrow-band UVB phototherapy and biomarkers for therapeutic response
-
e581-584
-
Tintle S, Shemer A, Suarez-Farinas M, et al. Reversal of atopic dermatitis with narrow-band UVB phototherapy and biomarkers for therapeutic response. J Allergy Clin Immunol 2011;128(3):583-93; e581-584
-
(2011)
J Allergy Clin Immunol
, vol.128
, Issue.3
, pp. 583-593
-
-
Tintle, S.1
Shemer, A.2
Suarez-Farinas, M.3
-
55
-
-
79952584368
-
Recent advances in IL-22 biology
-
Zenewicz LA, Flavell RA. Recent advances in IL-22 biology. Int Immunol 2011;23(3): 159-63
-
(2011)
Int Immunol
, vol.23
, Issue.3
, pp. 159-163
-
-
Zenewicz, L.A.1
Flavell, R.A.2
-
57
-
-
84879988459
-
A randomized phase 2a efficacy and safety trial of the topical Janus kinase inhibitor tofacitinib in the treatment of chronic plaque psoriasis
-
Ports WC, Khan S, Lan S, et al. A randomized phase 2a efficacy and safety trial of the topical Janus kinase inhibitor tofacitinib in the treatment of chronic plaque psoriasis. Br J Dermatol 2013; 169(1):137-45
-
(2013)
Br J Dermatol
, vol.169
, Issue.1
, pp. 137-145
-
-
Ports, W.C.1
Khan, S.2
Lan, S.3
-
58
-
-
84865592373
-
Efficacy and safety of tofacitinib, an oral Janus kinase inhibitor, in the treatment of psoriasis: A Phase 2b randomized placebo-controlled dose-ranging study
-
Papp KA, Menter A, Strober B, et al. Efficacy and safety of tofacitinib, an oral Janus kinase inhibitor, in the treatment of psoriasis: a Phase 2b randomized placebo-controlled dose-ranging study. Br J Dermatol 2012;167(3):668-77
-
(2012)
Br J Dermatol
, vol.167
, Issue.3
, pp. 668-677
-
-
Papp, K.A.1
Menter, A.2
Strober, B.3
-
61
-
-
84871127062
-
Emerging therapies for the treatment of psoriasis
-
Patel M, Day A, Warren RB, Menter A. Emerging therapies for the treatment of psoriasis. Dermatol Ther (Heidelb) 2012; 2(1):16
-
(2012)
Dermatol Ther (Heidelb)
, vol.2
, Issue.1
, pp. 16
-
-
Patel, M.1
Day, A.2
Warren, R.B.3
Menter, A.4
-
62
-
-
84893772728
-
EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2013 update
-
Smolen JS, Landewe R, Breedveld FC, et al. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2013 update. Ann Rheum Dis 2013
-
(2013)
Ann Rheum Dis
-
-
Smolen, J.S.1
Landewe, R.2
Breedveld, F.C.3
-
64
-
-
0032899660
-
Cyclic nucleotide phosphodiesterase (PDE) inhibitors and immunomodulation
-
Essayan DM. Cyclic nucleotide phosphodiesterase (PDE) inhibitors and immunomodulation. Biochem Pharmacol 1999;57(9):965-73
-
(1999)
Biochem Pharmacol
, vol.57
, Issue.9
, pp. 965-973
-
-
Essayan, D.M.1
-
65
-
-
84860175869
-
Apremilast mechanism of action and application to psoriasis and psoriatic arthritis
-
Schafer P. Apremilast mechanism of action and application to psoriasis and psoriatic arthritis. Biochem Pharmacol 2012;83(12): 1583-90
-
(2012)
Biochem Pharmacol
, vol.83
, Issue.12
, pp. 1583-1590
-
-
Schafer, P.1
-
66
-
-
14444268769
-
1,4-Cyclohexanecarboxylates: Potent and selective inhibitors of phosophodiesterase 4 for the treatment of asthma
-
Christensen SB, Guider A, Forster CJ, et al. 1,4-Cyclohexanecarboxylates: potent and selective inhibitors of phosophodiesterase 4 for the treatment of asthma. J Med Chem 1998;41(6):821-35
-
(1998)
J Med Chem
, vol.41
, Issue.6
, pp. 821-835
-
-
Christensen, S.B.1
Guider, A.2
Forster, C.J.3
-
67
-
-
1342264246
-
Antidepressant effects of inhibitors of cAMP phosphodiesterase (PDE4)
-
O'Donnell JM, Zhang HT. Antidepressant effects of inhibitors of cAMP phosphodiesterase (PDE4). Trends Pharmacol Sci 2004;25(3):158-63
-
(2004)
Trends Pharmacol Sci
, vol.25
, Issue.3
, pp. 158-163
-
-
O'donnell, J.M.1
Zhang, H.T.2
-
68
-
-
84898927150
-
Benefits and harms of roflumilast in moderate to severe COPD
-
[Epub ahead of print]
-
Yu T, Fain K, Boyd CM, et al. Benefits and harms of roflumilast in moderate to severe COPD. Thorax 2013. [Epub ahead of print]
-
(2013)
Thorax
-
-
Yu, T.1
Fain, K.2
Boyd, C.M.3
-
69
-
-
77249116286
-
Apremilast, a cAMP phosphodiesterase-4 inhibitor, demonstrates anti-inflammatory activity in vitro and in a model of psoriasis
-
Schafer PH, Parton A, Gandhi AK, et al. Apremilast, a cAMP phosphodiesterase-4 inhibitor, demonstrates anti-inflammatory activity in vitro and in a model of psoriasis. Br J Pharmacol 2010; 159(4):842-55
-
(2010)
Br J Pharmacol
, vol.159
, Issue.4
, pp. 842-855
-
-
Schafer, P.H.1
Parton, A.2
Gandhi, A.K.3
-
70
-
-
64349119966
-
Discovery of (S)-N-[2-[1-(3-ethoxy-4- methoxyphenyl)-2- methanesulfonylethyl]- 1,3-dioxo-2,3-dihy dro-1H-isoindol-4-yl] acetamide (apremilast), a potent and orally active phosphodiesterase 4 and tumor necrosis factor-alpha inhibitor
-
Man HW, Schafer P, Wong LM, et al. Discovery of (S)-N-[2-[1-(3-ethoxy-4- methoxyphenyl)-2-methanesulfonylethyl]- 1,3-dioxo-2,3-dihy dro-1H-isoindol-4-yl] acetamide (apremilast), a potent and orally active phosphodiesterase 4 and tumor necrosis factor-alpha inhibitor. J Med Chem 2009;52(6):1522-4
-
(2009)
J Med Chem
, vol.52
, Issue.6
, pp. 1522-1524
-
-
Man, H.W.1
Schafer, P.2
Wong, L.M.3
-
71
-
-
0029784855
-
Structural modifications of thalidomide produce analogs with enhanced tumor necrosis factor inhibitory activity
-
Muller GW, Corral LG, Shire MG, et al. Structural modifications of thalidomide produce analogs with enhanced tumor necrosis factor inhibitory activity. J Med Chem 1996;39(17):3238-40
-
(1996)
J Med Chem
, vol.39
, Issue.17
, pp. 3238-3240
-
-
Muller, G.W.1
Corral, L.G.2
Shire, M.G.3
-
72
-
-
0032747518
-
Suppression of human inflammatory cell function by subtype-selective PDE4 inhibitors correlates with inhibition of PDE4A and PDE4B
-
Manning CD, Burman M, Christensen SB, et al. Suppression of human inflammatory cell function by subtype-selective PDE4 inhibitors correlates with inhibition of PDE4A and PDE4B. Br J Pharmacol 1999;128(7):1393-8
-
(1999)
Br J Pharmacol
, vol.128
, Issue.7
, pp. 1393-1398
-
-
Manning, C.D.1
Burman, M.2
Christensen, S.B.3
-
73
-
-
0033952050
-
Phosphodiesterase and cyclic adenosine monophosphate-dependent inhibition of T-lymphocyte chemotaxis
-
Hidi R, Timmermans S, Liu E, et al. Phosphodiesterase and cyclic adenosine monophosphate-dependent inhibition of T-lymphocyte chemotaxis. Eur Respir J 2000;15(2):342-9
-
(2000)
Eur Respir J
, vol.15
, Issue.2
, pp. 342-349
-
-
Hidi, R.1
Timmermans, S.2
Liu, E.3
-
74
-
-
0032934381
-
The effects of phosphodiesterase type 4 inhibitors on tumour necrosis factor-alpha and leukotriene B4 in a novel human whole blood assay
-
Brideau C, Van Staden C, Styhler A, et al. The effects of phosphodiesterase type 4 inhibitors on tumour necrosis factor-alpha and leukotriene B4 in a novel human whole blood assay. Br J Pharmacol 1999;126(4):979-88
-
(1999)
Br J Pharmacol
, vol.126
, Issue.4
, pp. 979-988
-
-
Brideau, C.1
Van Staden, C.2
Styhler, A.3
-
76
-
-
84882372494
-
Efficacy, tolerability, and pharmacodynamics of apremilast in recalcitrant plaque psoriasis: A phase II open-label study
-
Gottlieb AB, Matheson RT, Menter A, et al. Efficacy, tolerability, and pharmacodynamics of apremilast in recalcitrant plaque psoriasis: a phase II open-label study. J Drugs Dermatol 2013;12(8):888-97
-
(2013)
J Drugs Dermatol
, vol.12
, Issue.8
, pp. 888-9777
-
-
Gottlieb, A.B.1
Matheson, R.T.2
Menter, A.3
-
77
-
-
33749009030
-
Mechanisms of Disease: The link between RANKL and arthritic bone disease
-
Schett G, Hayer S, Zwerina J, et al. Mechanisms of Disease: the link between RANKL and arthritic bone disease. Nat Clin Pract Rheumatol 2005;1(1):47-54
-
(2005)
Nat Clin Pract Rheumatol
, vol.1
, Issue.1
, pp. 47-54
-
-
Schett, G.1
Hayer, S.2
Zwerina, J.3
-
78
-
-
33749598017
-
Elevated serum levels of soluble receptor activator of nuclear factors-kappaB ligand (sRANKL) and reduced bone mineral density in patients with ankylosing spondylitis (AS)
-
Kim HR, Lee SH, Kim HY. Elevated serum levels of soluble receptor activator of nuclear factors-kappaB ligand (sRANKL) and reduced bone mineral density in patients with ankylosing spondylitis (AS). Rheumatology (Oxford, England) 2006; 45(10):1197-200
-
(2006)
Rheumatology (Oxford, England)
, vol.45
, Issue.10
, pp. 1197-1200
-
-
Kim, H.R.1
Lee, S.H.2
Kim, H.Y.3
-
79
-
-
44349161096
-
An open-label, single-arm pilot study in patients with severe plaque-type psoriasis treated with an oral anti-inflammatory agent
-
Gottlieb AB, Strober B, Krueger JG, et al. An open-label, single-arm pilot study in patients with severe plaque-type psoriasis treated with an oral anti-inflammatory agent. apremilast. Curr Med Res Opin 2008;24(5):1529-38
-
(2008)
Apremilast. Curr Med Res Opin
, vol.24
, Issue.5
, pp. 1529-1538
-
-
Gottlieb, A.B.1
Strober, B.2
Krueger, J.G.3
-
80
-
-
80655145912
-
Disposition, metabolism and mass balance of [(14)C]apremilast following oral administration
-
Hoffmann M, Kumar G, Schafer P, et al. Disposition, metabolism and mass balance of [(14)C]apremilast following oral administration. Xenobiotica 2011;41(12): 1063-75
-
(2011)
Xenobiotica
, vol.41
, Issue.12
, pp. 1063-1075
-
-
Hoffmann, M.1
Kumar, G.2
Schafer, P.3
-
81
-
-
84869014252
-
Oral apremilast in the treatment of active psoriatic arthritis: Results of a multicenter, randomized, double-blind, placebo-controlled study
-
Schett G, Wollenhaupt J, Papp K, et al. Oral apremilast in the treatment of active psoriatic arthritis: results of a multicenter, randomized, double-blind, placebo-controlled study. Arthritis Rheum 2012;64(10):3156-67
-
(2012)
Arthritis Rheum
, vol.64
, Issue.10
, pp. 3156-3167
-
-
Schett, G.1
Wollenhaupt, J.2
Papp, K.3
-
82
-
-
84898877815
-
Long-term (52-week) results of a phase 3, randomized, controlled trial of apremilast, an oral phosphodiesterase 4 inhibitor, in patients with psoriatic arthritis
-
Kavanaugh A, Mease PJ, Adebajo AO, et al. Long-term (52-week) results of a phase 3, randomized, controlled trial of apremilast, an oral phosphodiesterase 4 inhibitor, in patients with psoriatic arthritis. Ann Rheum Dis 2013;72:Suppl 3 163
-
(2013)
Ann Rheum Dis
, vol.72
, Issue.SUPPL. 3
, pp. 163
-
-
Kavanaugh, A.1
Mease, P.J.2
Adebajo, A.O.3
-
83
-
-
84899868819
-
-
American College of Rheumatology/Association of Rheumatology Health Professionals Annual Meeting; 26-30 October 2013; San Diego, CA, USA
-
Cutolo M MG, Fleischmann RM, Liote F, et al. Long-term (52-Week) results of a phase 3, randomized, controlled trial of apremilast, an oral phosphodiesterase 4 inhibitor, in patients with psoriatic arthritis (PALACE 2). 2013 American College of Rheumatology/Association of Rheumatology Health Professionals Annual Meeting; 26-30 October 2013; San Diego, CA, USA
-
(2013)
Long-term (52-Week) Results of A Phase 3, Randomized, Controlled Trial of Apremilast, An Oral Phosphodiesterase 4 Inhibitor, in Patients with Psoriatic Arthritis (PALACE 2)
-
-
Cutolo, M.M.G.1
Fleischmann, R.M.2
Liote, F.3
-
84
-
-
84901833481
-
-
American College of Rheumatology/ Association of Rheumatology Health Professionals Annual Meeting; 26-30 October 2013; San Diego, CA, USA
-
Edwards CJ, Blanco FJ, Crowley JH, et al. Long-term (52-week) results of a phase 3, randomized, controlled trial of apremilast, an oral phosphodiesterase 4 inhibitor, in patients with psoriatic arthritis and current skin involvement (PALACE 3). 2013 American College of Rheumatology/ Association of Rheumatology Health Professionals Annual Meeting; 26-30 October 2013; San Diego, CA, USA
-
(2013)
Long-term (52-week) Results of A Phase 3, Randomized, Controlled Trial of Apremilast, An Oral Phosphodiesterase 4 Inhibitor, in Patients with Psoriatic Arthritis and Current Skin Involvement (PALACE 3)
-
-
Edwards, C.J.1
Blanco, F.J.2
Crowley, J.H.3
-
85
-
-
84898900966
-
Apremilast, an oral phosphodiesterase 4 inhibitor, is associated with long-term (52-week) improvement in tender and swollen joint counts in patients with psoriatic arthritis: Results from three phase 3, randomized controlled trials [abstract 317]
-
Cutolo M MP, Gladman DD, Kavanaugh A, et al. Apremilast, an oral phosphodiesterase 4 inhibitor, is associated with long-term (52-week) improvement in tender and swollen joint counts in patients with psoriatic arthritis: results from three phase 3, randomized controlled trials [abstract 317]. Arthritis Rheum 2013; 65(10 Suppl):S135-6
-
(2013)
Arthritis Rheum
, vol.65
, Issue.10 SUPPL.
-
-
Cutolo, M.M.P.1
Gladman, D.D.2
Kavanaugh, A.3
-
86
-
-
84896137044
-
Apremilast, an oral phosphodiesterase 4 inhibitor, is associated with long-term (52-week) improvements in enthesitis and dactylitis in patients with psoriatic arthritis: Pooled results from three phase 3 randomized, controlled trials [abstract 816]
-
Gladman DD MP, Kavanaugh A, Adebajo AO, et al. Apremilast, an oral phosphodiesterase 4 inhibitor, is associated with long-term (52-week) improvements in enthesitis and dactylitis in patients with psoriatic arthritis: pooled results from three phase 3 randomized, controlled trials [abstract 816]. Arthritis Rheum 2013; 65(10 Suppl):S347
-
(2013)
Arthritis Rheum
, vol.65
, Issue.10 SUPPL.
-
-
Gladman, D.D.M.P.1
Kavanaugh, A.2
Adebajo, A.O.3
-
87
-
-
84896105372
-
Apremilast, an oral phosphodiesterase 4 inhibitor, is associated with long-term (52 -week) improvement in physical function in patients with psoriatic arthritis: Results from three phase 3, randomized controlled trials [abstract 331]
-
Schett G MP, Gladman DD, Kavanaugh A, et al. Apremilast, an oral phosphodiesterase 4 inhibitor, is associated with long-term (52 -week) improvement in physical function in patients with psoriatic arthritis: results from three phase 3, randomized controlled trials [abstract 331]. Arthritis Rheum 2013; 65(10 Suppl):S143
-
(2013)
Arthritis Rheum
, vol.65
, Issue.10 SUPPL.
-
-
Schett, G.M.P.1
Gladman, D.D.2
Kavanaugh, A.3
-
88
-
-
84898842169
-
-
American College of Rheumatology/Association of Rheumatology Health Professionals Annual Meeting; 26-30 October 2013; San Diego, CA, USA
-
Kavanaugh A. Considerations of psoriatic arthritis therapy selection. 2013 American College of Rheumatology/Association of Rheumatology Health Professionals Annual Meeting; 26-30 October 2013; San Diego, CA, USA
-
(2013)
Considerations of Psoriatic Arthritis Therapy Selection
-
-
Kavanaugh, A.1
-
89
-
-
84898920453
-
-
American College of Rheumatology Annual Meeting Arthritis Rheum
-
Wells AF EC, Adebajo AO, Kivitz AJ, et al. Apremilast in the treatment of DMARD-naive psoriatic arthritis patients: results of a phase 3, randomized, controlled trial (PALACE-4). American College of Rheumatology Annual Meeting Arthritis Rheum 2013. 65
-
(2013)
Apremilast in the Treatment of DMARD-naive Psoriatic Arthritis Patients: Results of A Phase 3, Randomized, Controlled Trial (PALACE-4)
, pp. 65
-
-
Wells, A.F.E.C.1
Adebajo, A.O.2
Kivitz, A.J.3
-
90
-
-
84901841741
-
-
American College of Rheumatology/ Association of Rheumatology Health Professionals Annual Meeting; 26-30 October 2013; San Diego, CA, USA
-
Mease PK, Gladman DD, Adebajo AO, et al. Long-term safety and tolerability of apremilast, an oral phosphodiesterase 4 inhibitor, in patients with psoriatic arthritis: pooled safety analysis of three phase 3, randomized, controlled trials. 2013 American College of Rheumatology/ Association of Rheumatology Health Professionals Annual Meeting; 26-30 October 2013; San Diego, CA, USA
-
(2013)
Long-term Safety and Tolerability of Apremilast, An Oral Phosphodiesterase 4 Inhibitor, in Patients with Psoriatic Arthritis: Pooled Safety Analysis of Three Phase 3, Randomized, Controlled Trials
-
-
Mease, P.K.1
Gladman, D.D.2
Adebajo, A.O.3
Et, A.4
-
91
-
-
77949350034
-
Identification of a primary target of thalidomide teratogenicity
-
Ito T, Ando H, Suzuki T, et al. Identification of a primary target of thalidomide teratogenicity. Science 2010; 327(5971):1345-50
-
(2010)
Science
, vol.327
, Issue.5971
, pp. 1345-1350
-
-
Ito, T.1
Ando, H.2
Suzuki, T.3
-
92
-
-
84869082150
-
Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide
-
Lopez-Girona A, Mendy D, Ito T, et al. Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide. Leukemia 2012;26(11): 2326-35
-
(2012)
Leukemia
, vol.26
, Issue.11
, pp. 2326-2335
-
-
Lopez-Girona, A.1
Mendy, D.2
Ito, T.3
-
93
-
-
84889657887
-
Effect of different imputation approaches on the evaluation of radiographic progression in patients with psoriatic arthritis: Results of the RAPID-PsA 24-week phase III double-blind randomised placebo-controlled study of certolizumab pegol
-
van der Heijde D, Fleischmann R, Wollenhaupt J, et al. Effect of different imputation approaches on the evaluation of radiographic progression in patients with psoriatic arthritis: results of the RAPID-PsA 24-week phase III double-blind randomised placebo-controlled study of certolizumab pegol. Ann Rheum Dis 2014; 73(1):233-7
-
(2014)
Ann Rheum Dis
, vol.73
, Issue.1
, pp. 233-237
-
-
Van Der Heijde, D.1
Fleischmann, R.2
Wollenhaupt, J.3
-
94
-
-
84889668023
-
Effect of certolizumab pegol on signs and symptoms in patients with psoriatic arthritis: 24-week results of a Phase 3 double-blind randomised placebo-controlled study (RAPID-PsA)
-
Mease PJ, Fleischmann R, Deodhar AA, et al. Effect of certolizumab pegol on signs and symptoms in patients with psoriatic arthritis: 24-week results of a Phase 3 double-blind randomised placebo-controlled study (RAPID-PsA). Ann Rheum Dis 2014;73(1):48-55
-
(2014)
Ann Rheum Dis
, vol.73
, Issue.1
, pp. 48-55
-
-
Mease, P.J.1
Fleischmann, R.2
Deodhar, A.A.3
-
95
-
-
84873124241
-
Efficacy and safety of secukinumab in the treatment of moderate-to-severe plaque psoriasis: A randomized, double-blind, placebo-controlled phase II dose-ranging study
-
Papp KA, Langley RG, Sigurgeirsson B, et al. Efficacy and safety of secukinumab in the treatment of moderate-to-severe plaque psoriasis: a randomized, double-blind, placebo-controlled phase II dose-ranging study. Br J Dermatol 2013;168(2):412-21
-
(2013)
Br J Dermatol
, vol.168
, Issue.2
, pp. 412-421
-
-
Papp, K.A.1
Langley, R.G.2
Sigurgeirsson, B.3
|