Highly increased levels of tumor necrosis factor-α and other proinflammatory cytokines in psoriatric arthritis synovial fluid

Journal of Rheumatology

Volumn 24, Issue 3, 1997, Pages 518-523

  Partsch, Gerald ^a,b   Steiner, Günter ^a   Leeb, Burkhard F ^a,c   Dunky, Attila ^a,d   Bröll, Hans ^a,b,e   Smolen, Josef S ^a,c,f  

^a LUDWIG BOLTZMANN INSTITUTE FOR LUNG VASCULAR RESEARCH   (Austria)

^b Department of Clinical Biochemistry ^*

^c GENERAL HOSPITAL LINZ   (Austria)

^d Wilhelminenspital   (Austria)

^e KAISER FRANZ JOSEF HOSPITAL   (Austria)

^f MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

cytokines; psoriatic arthritis; rheumatoid arthritis

Indexed keywords

AZATHIOPRINE; CHLOROQUINE; GOLD SALT; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; METHOTREXATE; PENICILLAMINE; PREDNISOLONE; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; OSTEOARTHRITIS; PRIORITY JOURNAL; PSORIATIC ARTHRITIS; RHEUMATOID ARTHRITIS; SYNOVIAL FLUID;

ANTIRHEUMATIC AGENTS; ARTHRITIS, PSORIATIC; FEMALE; HUMANS; INTERLEUKIN-1; INTERLEUKIN-6; INTERLEUKIN-8; MALE; MIDDLE AGED; SYNOVIAL FLUID; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0030905089     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Arend WP, Dayer J-M: Cytokines and cytokine inhibitor or antagonists in rheumatoid arthritis. Arthritis Rheum 1990;33:305-15.
2. Arend WP, Dayer J-M: Inhibition of the production and effects of interleukin-1 and tumor necrosis factor α in rheumatoid arthritis. Arthritis Rheum 1995;38:151-60.
3. Brennan FM, Maini RN, Feldmann M: TNF-α - a pivotal role in rheumatoid arthritis? Br J Rheumatol 1992;31:293-8.
4. Holt I, Cooper RG, Denton J, Meager A, Hopkins SJ: Cytokine inter-relationships and their association with disease activity in arthritis. Br J Rheumatol 1992;31:725-33.
5. Di Giovine FS, Manson J, Nuki G, Duff GW: The presence of tumor necrosis factor activity in synovial exudate fluids from patients with osteoarthritis or rheumatoid arthritis (abstr). Br J Rheumatol 1986;25:A108.
6. Steiner G, Studnicka-Benke A, Witzmann G, Höfler E, Smolen J: Soluble receptors for tumor necrosis factor and interleukin-2 in serum and synovial fluid of patients with rheumatoid arthritis, reactive arthritis and osteoarthritis. J Rheumatol 1995;22:406-12.
7. Eastgate JA, Symons JA, Wood NC, Grinlinton FM, di Giovine FS, Duff GW: Correlation of plasma interleukin-1 levels with disease activity in rheumatoid arthritis. Lancet 1988;2:706-9.
8. Firestein GS, Zvaifler NJ: How important are T cells in chronic rheumatoid synovitis? Arthritis Rheum 1990;33:768-72.
9. Smolen JS, Tohidast-Akrad M, Gal A, et al: The role of T-lymphocytes and cytokines in rheumatoid arthritis. Scand J Rheumatol 1996;25:1-4.
10. Simon AK, Seipelt E, Sieper J: Divergent T-cell cytokine patterns in inflammatory arthritis. Proc Natl Acad Sci USA 1994;91:8562-6.
11. Gladman DD: Natural history of psoriatic arthritis. Baillière's Clin Rheumatol 1994;8:379-94.
12. Wright V, Moll JMH: Seronegative polyarthritis. Amsterdam: North Holland, 1976:169-223.
13. Gladman DD, Anhorn KAB, Schachter RK, Mervart H: Psoriatic arthritis (PSA) - an analysis of 220 patients. Q J Med 1987;62:127-41.
14. Gladman DD, Farewell VT: The role of HLA antigens as indicators of disease progression in psoriatic arthritis. Arthritis Rheum 1995;38:845-50.
15. Partsch G, Petera P, Leeb B, et al: High free and latent collagenase activity in psoriatic arthritis synovial fluids. Br J Rheumatol 1994;33:702-6.
16. 2 production by synovial cells. J Clin Invest 1986;77:645-8.
17. 2 production by human synovial cells and dermal fibroblasts. J Exp Med 1985;162:2163-8.
18. Arnett FC, Edworthy SM, Bloch DA, et al: The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315-24.
19. Roux-Lombard P, Steiner G, and the Cytokine Consensus Study Group of the European Workshop for Rheumatology Research: Preliminary report on cytokine determination in human synovial fluids: A consensus study of the European Workshop for Rheumatology Research. Clin Exp Rheumatol 1992;10:515-20.
20. Houssiau FA, Devogelaer JP, van Damme J, Nagant de Deuxchaisnes C, van Snick I: Interleukin-6 in synovial fluid and serum of patients with rheumatoid arthritis and other inflammatory arthritides. Arthritis Rheum 1988;31:784-8.
21. Di Giovine FS, Nuki G, Duff GW: Tumour necrosis factor in synovial exudates. Ann Rheum Dis 1988;41:768-72.
22. Saxne TM, Palladino MA Jr, Heinegard D, Talal N, Wollheim FA: Detection of tumor necrosis factor alpha but not tumor necrosis factor beta in rheumatoid arthritis synovial fluid and serum. Arthritis Rheum 1988;31:1041-4.
23. Roux-Lombard P, Punzi L, Hasler F, et al: Soluble tumor necrosis factor receptors in human inflammatory synovial fluids. Arthritis Rheum 1993;36:485-9.
24. Elliott MJ, Maini RN, Feldmann M, et al: Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor α (cA2) versus placebo in rheumatoid arthritis. Lancet 1994;344:1105-10.
25. Symons JA, McDowell TL, di Giovine FS, Wood NC, Capper SJ, Duff GW: Interleukin-1 in rheumatoid arthritis: Potentiation of immune responses within the joint. Lymphokine Res 1989;8:365-72.
26. Di Giovine FS, Poole S, Situnayake RD, Wadhwa M, Duff GW: Absence of correlations between indices of systemic inflammation and synovial fluid interleukin 1 (alpha and beta) in rheumatic diseases. Rheumatol Int 1990;9:259-64.
27. Rooney M, Symons JA, Duff GW: Interleukin-1 beta in synovial fluid in relating to local disease activity in rheumatoid arthritis. Rheumatol Int 1990;10:217-9.
28. Pianon M, Punzi L, Stefani MP, et al: Interleukin-1 beta, plasminogen activator and inhibitor of plasminogen activator in synovial fluid of rheumatoid arthritis, psoriatic arthritis and osteoarthritis. Agents Actions 1994;41:88-9.
29. Holt I, Cooper RG, Hopkins SJ: Relationships between local inflammation, interleukin-6 concentration and the acute phase protein response in arthritis patients. Eur J Clin Invest 1991;21:479-84.
30. Van Snick J: Interleukin-6: An overview. Annu Rev Immunol 1990;8:253-18.
31. Castell JV, Gomez-Lechon MJ, David M, et al: Interleukin 6 is the major regulator of acute phase protein synthesis in adult human hepatocytes. FEBS Lett 1989;242:237-9.
32. Yoshimura T, Robinson EA, Tanaka S, Appella E, Leonard EJ: Purification and aminoacid analysis of two human monocyte chemoattractants produced by phytohemagglutinin-stimulated human blood mononuclear leukocytes. J Immunol 1989;142:1956-62.
33. Gregory H, Young J, Schröder J-M, Mrowietz U, Christophers E: Structure determination of a human lymphocyte derived neutrophil activating peptide (LYNAP). Biochem Biophys Res Commun 1988;151:883-90.
34. Rathanaswami P, Hachicha M, Wong WL, Schall TJ, McColl SR: Synergistic effect of interleukin-1β and tumor necrosis factor α on interleukin-8 gene expression in synovial fibroblasts. Arthritis Rheum 1993;36:1295-304.
35. Koch AE, Kunkel SL, Burrows JC, et al: Synovial tissue macrophage as a source of the chemotactic cytokine IL-8. J Immunol 1991;147:2187-95.
36. Veale D, Yanni G, Rogers S, Barnes L, Bresnihan B, Fitzgerald O: Reduced synovial membrane macrophage numbers, ELAM-1 expression, and lining layer hyperplasia in psoriatic arthritis as compared with rheumatoid arthritis. Arthritis Rheum 1993;36:893-900.
37. Barrera P, Boerbooms AMT, van de Putte LBA, van der Meer JWM: Effects of antirheumatic agents on cytokines. Semin Arthritis Rheum 1996;25:234-53.