Effect of oil and co-surfactant on the formation of Solutol HS 15 based colloidal drug carrier by Box-Behnken statistical design

Colloids and Surfaces A: Physicochemical and Engineering Aspects

Volumn 453, Issue 1, 2014, Pages 68-77

  Ahmad, Javed ^a   Mir, Showkat R ^a   Kohli, Kanchan ^a   Amin, Saima ^a  

^a HAMDARD UNIVERSITY   (India)

Author keywords

Box Behnken design; Percentage transmittance; Pseudoternary phase diagrams; Self emulsifying system; Surfactant cosurfactant mass ratio

Indexed keywords

DESIGN; MICROEMULSIONS; OPTIMIZATION; STATISTICAL MECHANICS; SURFACE ACTIVE AGENTS;

BOX-BEHNKEN DESIGN; MASS RATIO; PERCENTAGE TRANSMITTANCE; PSEUDOTERNARY PHASE DIAGRAMS; SELF-EMULSIFYING;

EMULSIFICATION;

CAPRIC TRIGLYCERIDE; CAPRYLIC TRIGLYCERIDE; COSURFACTANT; DRUG CARRIER; EMULSIFYING AGENT; GLYCEROL OLEATE; GLYCERYL MONOLINOLEATE; MACROGOL 400; NONIONIC SURFACTANT; OIL; PACLITAXEL; PROPYLENE GLYCOL; PROPYLENE GLYCOL DICAPRYLOCAPRATE; PROPYLENE GLYCOL MONOCAPRYLATE; PROPYLENE GLYCOL MONOLAURATE; SEFSOL 218; SOLUTOL HS 15; SURFACTANT; TRANSCUTOL HP; UNCLASSIFIED DRUG; WATER;

AQUEOUS SOLUTION; ARTICLE; BOX BEHNKEN DESIGN; CALIBRATION; CENTRIFUGATION; CHEMICAL COMPOSITION; CHEMICAL STRUCTURE; CONTROLLED STUDY; DISPERSION; DRUG DESIGN; DRUG FORMULATION; DRUG SOLUBILITY; DRUG STABILITY; FREEZE THAWING; HEATING; MASS; NANOEMULSION; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SOLUBILIZATION; STATISTICAL ANALYSIS; THERMODYNAMICS;

EID: 84898793152     PISSN: 09277757     EISSN: 18734359     Source Type: Journal    
DOI: 10.1016/j.colsurfa.2014.04.008     Document Type: Article

References (46)

1. Barratt G.M. Therapeutic applications of colloidal drug carriers. Pharm. Sci. Technol. Today 2000, 3(5):163-171.
2. Muller-Goymann C.C. Physicochemical characterization of colloidal drug delivery systems such as reverse micelles, vesicles, liquid crystals and nanoparticles for topical administration. Eur. J. Pharm. Biopharm. 2004, 58:343-356.
3. Ahmad J., Kohli K., Mir S.R., Amin S. Self-emulsifying nano carriers for improved oral bioavailability of lipophilic drugs. Rev. Adv. Sci. Eng. 2012, 1(2):134-147.
4. Lawrence M.J., Rees G.D. Microemulsion-based media as novel drug delivery systems. Adv. Drug. Deliv. Rev. 2000, 45:89-121.
5. Wennerstrrom H., Balogh J., Olsson U. Interfacial tensions in microemulsions. Colloids Surf. A: Physicochem. Eng. Aspects 2006, 291:69-77.
6. Israelachvilli J.N., Mitchell D.J., Ninham B.W. Theory of self assembly of hydrocarbon amphiphiles into micelles and bilayers. J. Chem. Soc. Faraday Trans. 2 1976, 72:1525-1567.
7. Hiuberts P.D.T., Shah D.O. Evidence for synergism of nonionic surfactant mixtures: enhancement of solubilization in water-in-oil microemulsions. Langmuir 1997, 13:5762-5765.
8. Sagitani H., Friberg S. Microemulsion systems with a non-ionic cosurfactant. J. Dispers. Sci. Technol. 1980, 1:151-164.
9. Kommuru T.R., Gurley B., Khan M.A., Reddy I.K. Self-emulsifying drug delivery systems (SEDDS) of coenzyme Q10: formulation development and assessment. Int. J. Pharm. 2001, 212:233-246.
10. Gelderblom H., Verweij J., Nooter K., Sparreboom A. Cremophor EL: the drawbacks and advantages of vehicle selection for drug formulation. Eur. J. Cancer 2001, 37(13):1590-1598.
11. Coon J.S., Knudson W., Clodfelter K., Lu B., Weinstein R.S. Solutol HS 15, nontoxic polyoxyethylene esters of 12-hydroxystearic acid, reverses multidrug resistance. Cancer Res. 1991, 51:897-902.
12. Ku S., Velagaleti R. Solutol HS15 as a novel excipient. Pharm. Technol. Online 2010, 108-110.
13. Buckingham L.E., Balasubramanian M., Safa A.R., Shah H., Komarov P., Emanuele R.M., Coon J.S. Reversal of multi-drug resistance in vitro by fatty acid PEG fatty acid diesters. Int. J. Cancer 1996, 65:74-79.
14. Komarov P.G., Shtil A.A., Buckingham L.E., Balasubramanian M., Piraner O., Emanuele R.M., Roninson I.B., Coon J.S. Inhibition of cytarabine-induced MDR1 (P-glycoprotein) gene activation in human tumor cells by fatty acid-polyethyleneglycol fatty acid diesters, novel inhibitors of P-glycoprotein function. Int. J. Cancer 1996, 68:245-250.
15. Bittner B., Gonzalez R.C., Walter I., Kapps M., Huwyler J. Impact of Solutol HS 15 on the pharmacokinetic behaviour of colchicine upon intravenous administration to male Wistar rats. Biopharm. Drug Dispos. 2003, 24(4):173-181.
16. Zidan A.S., Sammour O.A., Hammad M.A., Megrab N.A., Habib M.J., Khan M.A. Quality by design: understanding the formulation variables of a cyclosporine A self-nanoemulsified drug delivery systems by Box-Behnken design and desirability function. Int. J. Pharm. 2007, 332(1-2):55-63.
17. Bravo Gonzalez R.C., Huwyler J., Boess F., Walter I., Bittner B. In-vitro investigation on the impact of the surface-active excipients Cremophor EL, Tween 80 and Solutol HS 15 on the metabolism of midazolam, Biopharm. Drug Dispos. 2004, 25(1):37-49.
18. Shafiq S., Shakeel F., Talegaonkar S., Ahmad F.J., Khar R.K., Ali M. Development and bioavailability assessment of ramipril nanoemulsion formulation. Eur. J. Pharm. Biopharm. 2007, 66(2):227-243.
19. Mustafa G., Khan Z.I., Bansal T., Talegaonkar S. Preparation and characterization of oil in water nano-reservoir systems for improved oral delivery of atorvastatin. Curr. Nanosci. 2009, 5(4):428-440.
20. Parveen R., Baboota S., Ali J., Ahuja A., Vasudev S.S., Ahmad S. Oil based nanocarrier for improved oral delivery of silymarin: in vitro and in vivo studies. Int. J. Pharm. 2011, 413(1-2):245-253.
21. Shafiq-un-Nabi S., Shakeel F., Talegaonkar S., Ali J., Baboota S., Ahuja A., Khar R.K., Ali M. Formulation development and optimization using nanoemulsion technique: a technical note. AAPS PharmSciTech 2007, 8(2):E12-E17.
22. Gao Z.G., Choi H.G., Shin H.J., Park K.M., Lim S.J., Hwang K.J., Kim C.K. Physicochemical characterization and evaluation of a microemulsion system for oral delivery of cyclosporin A. Int. J. Pharm. 1998, 161:75-86.
23. Xi J., Chang Q., Chan C.K., Meng Z.Y., Wang G.N., Sun J.B., Wang Y.T., Tong H.H., Zheng Y. Formulation development and bioavailability evaluation of a self-nanoemulsified drug delivery system of oleanolic acid. AAPS PharmSciTech 2009, 10(1):172-182.
24. Wang Z., Sun J., Wang Y., Liu X., Liu Y., Fu Q., Meng P., He Z. Solid self-emulsifying nitrendipine pellets: preparation and in vitro/in vivo evaluation. Int. J. Pharm. 2010, 383(1-2):1-6.
25. Box G.E.P., Behnken D.W. Some new three level designs for the study of quantitative variables. Technometrics 1960, 2(4):455-475.
26. Kincl M., Turk S., Vrecer F. Application of experimental design methodology in development and optimization of drug release method. Int. J. Pharm. 2005, 291(1-2):39-49.
27. Huizing M.T., Sewberath-Misser V.H., Pieters R.C., Ten Bokkel Huinink W.W., Veenhof C.H.N., Vermorken J.B., Pinedo H.M., Beijnen J.H. Taxanes: a new class of antitumor agents. Cancer Invest. 1995, 13:381-404.
28. Singla A.K., Garg A., Aggarwal D. Paclitaxel and its formulations. Int. J. Pharm. 2002, 235:179-192.
29. Ahmad J., Kohli K., Mir S.R., Amin S. Formulation of Self-Nanoemulsifying Drug Delivery System for Telmisartan with improved dissolution and oral bioavailability. J. Dispers. Sci. Technol. 2011, 32(7):958-996.
30. Sjoblom J., Lindbergh R., Friberg S.E. Microemulsions-phase equilibria characterization, structures, applications and chemical reactions. Adv. Colloid Interface Sci. 1996, 65:125-287.
31. Kundu K., Paul B.K. Physicochemical investigation of mixed surfactant reverse micelles: water solubilization and conductometric studies. Colloids Surf., A 2013, 433:154-165.
32. Chaudhary H., Kohli K., Amin S., Rathee P., Kumar V. Optimization and formulation design of gels of Diclofenac and Curcumin for transdermal drug delivery by Box-Behnken statistical design. J. Pharm. Sci. 2011, 100(2):580-593.
33. Tenjarla S. Microemulsions: an overview and pharmaceutical applications. Crit. Rev. Ther. Drug Carrier Syst. 1999, 16:461-521.
34. Paramar N., Singhla N., Amin S., Kohli K. Study of cosurfactant effect on nanoemulsifying area and development of lercanidipine loaded (SNEDDS) self nanoemulsifying drug delivery system. Colloids Surf. B: Biointerfaces 2011, 86:327-338.
35. Elnaggar Y.S., El-Massik M.A., Abdallah O.Y. Self-nanoemulsifying drug delivery systems of tamoxifen citrate: design and optimization. Int. J. Pharm. 2009, 380(1-2):133-141.
36. Li P., Ghosh A., Wagner R.F., Krill S., Joshi Y.M., Serajuddin A.T. Effect of combined use of nonionic surfactant on formation of oil-in-water microemulsions. Int. J. Pharm. 2005, 288(1):27-34.
37. Khoo S.M., Humberstone A.J., Porter C.J.H., Edwards G.A., Charman W.N. Formulation design and bioavailability assessment of lipidic Selfemulsifying formulations of halofantrine. Int. J. Pharm. 1998, 167:155-164.
38. Rang M.J., Miller C.A. Spontaneous emulsification of oils containing hydrocarbon, nonionic surfactant, and oleyl alcohol. J. Colloid Interface Sci. 1999, 209:179-192.
39. Shakeel F., Haq N., El-Badry M., Alanazi F.K., Alsarra I.A. Ultra fine super self-nanoemulsifying drug delivery system (SNEDDS) enhanced solubility and dissolution of indomethacin. J. Mol. Liq. 2013, 180:89-94.
40. Warisnoicharoen W., Lansley A.B., Lawrence M.J. Nonionic oil in water microemulsions: effect of oil type on phase behavior. Int. J. Pharm. 2000, 198:7-27.
41. Hua L., Weisan P., Jiayu L., Ying Z. Preparation, evaluation and NMR characterization of vinpocetine microemulsion for transdermal delivery. Drug Dev. Ind. Pharm. 2004, 30:657-666.
42. Malcolmson C., Satra C., Kantaria S., Sidhu A., Lawrence M.J. Effect of oil on the level of solubilization of testosterone propionate into nonionic oil-in-water microemulsions. J. Pharm. Sci. 1998, 87:109-116.
43. Rhee Y.S., Choi J.G., Park E.S., Chi S.C. Transdermal delivery of ketoprofen using microemulsions. Int. J. Pharm. 2001, 228:161-170.
44. Huang Y.B., Tsai Y.H., Lee S.H., Chang J.S., Wu P.C. Optimization of pH-independent release of nicardipine hydrochloride extended-release matrix tablets using response surface methodology. Int. J. Pharm. 2005, 289:87-95.
45. Subramanian N., Ray S., Ghosal S.K., Bhadra R., Moulik S.P. Formulation design of self-microemulsifying drug delivery systems for improved oral bioavailability of celecoxib. Biol. Pharm. Bull. 2004, 27:1993-1999.
46. Pouton C.W. Lipid formulations for oral administration of drugs: non-emulsifying, self-emulsifying and 'self-microemulsifying' drug delivery systems. Eur. J. Pharm. Sci. 2000, 11:S93-S98.