Nonionic oil-in-water microemulsions: The effect of oil type on phase behaviour

International Journal of Pharmaceutics

Volumn 198, Issue 1, 2000, Pages 7-27

  Warisnoicharoen, W ^a   Lansley, A B ^a   Lawrence, M J ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

N,N Dimethyl alkylamine N oxide surfactants; Nonionic oil in water microemulsions; Polyoxyethylene ether surfactants

Indexed keywords

BUTYRIC ACID ETHYL ESTER; CAPRYLIC ACID ETHYL ESTER; MIGLYOL; N,N DIMETHYLDODECYLAMINE OXIDE; N,N DIMETHYLOLEYLAMINE N OXIDE; NONIONIC SURFACTANT; OIL; OLEIC ACID ETHYL ESTER; POLIDOCANOL; POLYOXYETHYLENE OLEYL ETHER; SOYBEAN OIL; TRIBUTYRIN; UNCLASSIFIED DRUG;

ARTICLE; MICROEMULSION; MOLECULAR DYNAMICS; MOLECULAR STABILITY; PHASE TRANSITION; PRIORITY JOURNAL; THERMODYNAMICS; THERMOSTABILITY;

AMINES; CHEMISTRY, PHYSICAL; CHROMATOGRAPHY, THIN LAYER; ELECTROLYTES; EMULSIONS; ESTERS; OILS; POLYETHYLENE GLYCOLS; SURFACE-ACTIVE AGENTS; TEMPERATURE; WATER;

EID: 0034732053     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(99)00406-8     Document Type: Article

References (38)

1. Aboofazeli R., Patel N., Thomas M., Lawrence M.J. Investigations into the formation and characterization of phospholipid microemulsions. IV. Pseudo-ternary phase diagrams of systems containing water-lecithin-oil and cosurfactant. Int. J. Pharm. 125:1995;107-116.
2. Adam R.L.P. Laboratory Techniques in Biochemistry and Molecular Biology: Cell Culture for Biochemists. 1980;246-248 Elsevier, Amsterdam.
3. Attwood D. Colloidal drug delivery systems. Kreuter J. Microemulsions. 1994;31-71 Marcel Dekker, New York.
4. Aveyard R., Lawless T.A. Interfacial tension minima in oil-water surfactant systems. J. Chem. Soc. Faraday Trans. 182:1986;2951-2963.
5. Chaiko M.A., Nagarajan R., Ruckenstein E. Solubilisation of single-component and binary mixtures of hydrocarbons in aqueous micellar solutions. J. Colloid Interface Sci. 99:1984;168-182.
6. Chen S.J., Evans D.F., Ninham B.W., Mitchell D.J., Blum F.D., Pickup S. Curvature as a determinant of microstructure and microemulsions. J. Phys. Chem. 90:1986;842-847.
7. Dulbecoco R., Vogt M. Plaque formation and isolation of pure lines with poliomyelitis virus. J Exp. Med. 99:1954;167-182.
8. Evans D.R., Mitchell D.J., Ninham B.W. Oil, water and surfactant: properties and conjectured structure of simple microemulsions. J Phys. Chem. 90:1986;2817-2825.
9. Gradzielski M., Hoffmann H. Influence of charges on structure and dynamics of an o/w microemulsion. Effect of admixing ionic surfactants. J Phys Chem. 98:1994;2613-2623.
10. Gu T., Sjöblom J. Surfactant structure and its relation to the Kraft point, cloud point and micellization: some emperical relationships. Colloids Surf. 64:1992;39-46.
11. Hamdam S., Faujan B.H.A., Laili C.R., Ahmad W.B.W., Dzulkefly K. Water/food flavor microemulsion systems. J Agric. Food Chem. 44:1996;962-963.
12. Hoffman H., Rauscher A., Gradzielski M., Schulz S.F. Influence of ionic surfactants on the viscoelastic properties of zwitterionic surfactant solutions. Langmuir. 8:1992;2140-2146.
13. Hoffmann H., Gradzielski M. Influence of charges on structure and dynamics of an oil-in-water microemulsion - effect of admixing ionic surfactant. J. Phys. Chem. 98:1994;2613-2623.
14. Imae T., Ikeda S. Intermicellar correlation in light scattering from dilute micellar solutions of dimethyloleylamine oxide. J. Colloid Interface Sci. 98:1984;363-372.
15. Lawrence M.J., Devinsky F. The solubilising capacity of a series of non-aromatic amine oxide surfactants. J. Pharm. Pharmacol. 40(Suppl.):1988;125P.
16. Lawrence M.J. Microemulsions as drug delivery vehicles. Curr. Opin. Colloid Interface Sci. 1:1994;826-832.
17. Lu, J.R., Su, T.J., Zuberi, T., Warisnoicharoen, W., Lawrence, M.J., Barlow, D.J., 1999. The structure and composition of ethyl hexadecanoate layers spread on aqueous solutions of hexaethylene glycol monodecyl ether, J. Phys. Chem. B 103, 4638-4648.
18. Malcolmson C., Lawrence M.J. A comparison of the incorporation of model steroids into non-ionic micellar and microemulsion systems. J. Pharm. Pharmacol. 45:1993;141-143.
19. Malcolmson C., Lawrence M.J. Three-component non-ionic oil-in-water microemulsions using polyoxyethylene ether surfactants. Colloids Surf. B Biointerfaces. 4:1995;97-109.
20. Malcolmson C., Sidhu A., Satra C., Kantaria S., Lawrence M.J. Effect of the nature of oil on the incorporation of testosterone propionate into non-ionic oil-in-water microemulsions. J. Pharm. Sci. 87:1998;109-116.
21. Malcolmson C. The physicochemical properties of nonionic oil-in-water microemulsions. 1992;University of London. PhD Thesis.
22. McFann G.J., Johnston K.P. Phase behaviour of nonionic surfactant/oil/water systems containing light alkanes. Langmuir. 9:1993;2942-2948.
23. Mehta C., Thomas M., Lawrence M.J. Lecithin-based oil-in-water microemulsions. J. Pharm. Pharmacol. 46:1994;1058.
24. Miñana-Pérez M., Graciaa A., Lachaise J., Salager J.L. Solubilization of polar oils with extended surfactants. Colloids Surf. A: Physicochem. Eng. Aspects. 100:1995;217-224.
25. Miñana-Pérez M., Graciaa A., Lachaise J., Salager J.L. Solubilization of polar oils in microemulsion systems. Prog. Colloid Polym. Sci. 98:1995;177-179.
26. Monduzzi M., Caboi F., Larch F., Olsson U. DDAB microemulsions-dependence on the oil chain length. Langmuir. 13:1997;2184-2190.
27. Murthy A.K. Aqueous and nonaqueous microemulsions with high molecular weight alkanes. Colloid Polym. Sci. 271:1993;209-216.
28. Porter M.R. Handbook of Surfactants. 1991;116-178 Blackie and Son, London.
29. Satra C., Thomas M., Lawrence M.J. The solubility of testosterone propionate in oil-in-water microemulsions. J. Pharm. Pharmacol. 47:1995;1126.
30. Satra C. Oil-in-water microemulsions for pulmonary delivery. 1998;University of London. PhD Thesis.
31. Schott H., Han S.K. Effect of inorganic additives on solutions of nonionic surfactants II. J. Pharm. Sci. 64:1975;658-664.
32. Schott H., Royce A.E. Effect of inorganic additives on solutions of nonionic surfactants IV: further cloud point relations. J. Pharm. Sci. 73:1984;793-799.
33. Schott H. Hydrophile-lipophilie balance and cloud points of nonionic surfactants. J. Pharm. Sci. 58:1969;1443-1449.
34. Schott H. Salting in of nonionic surfactants by complexation with inorganic salts. J. Colloid Interface Sci. 43:1973;150-155.
35. Schuber K.V., Kaler E.W. Nonionic microemulsions. Ber. Bunsenges Phys. Chem. 100:1996;190-205.
36. Tanford C. Theory of micelle formation in aqueous solutions. J. Phys. Chem. 78:1974;2469-2479.
37. Tolle, S., Zuberi, T., Zuberi, S., Warisonoicharoen, W., Lawrence, M.J., 2000. Physico-chemical and soloubilization properties of N,N-dimethyl-N-(3-dodecylcarbonyloxypropyl)-amineoxide: a Biodegradable Nonionic surfactant, J. Pharm. Sci., in press.
38. Warisonoicharoen W. Pharmaceutical nonionic oil-in-water microemulsions. 1998;University of London. PhD Thesis.