Distinct structural and catalytic roles for Zap70 in formation of the immunological synapse in CTL

eLife

Volumn 2014, Issue 3, 2014, Pages

  Jenkins, Misty R ^a   Stinchcombe, Jane C ^a   Au Yeung, Byron B ^b,d   Asano, Yukako ^a   Ritter, Alex T ^a,c   Weiss, Arthur ^b,d   Griffiths, Gillian M ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CD3 ANTIGEN; CD8 ANTIGEN; GAMMA INTERFERON; INTEGRIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 2; LACTATE DEHYDROGENASE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN KINASE LCK; PROTEIN KINASE ZAP 70; T LYMPHOCYTE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; VAV PROTEIN; ZAP70 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; CATALYSIS; CD4+ T LYMPHOCYTE; CELL DEATH; CELL MEMBRANE; CENTROSOME; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; CYTOTOXICITY; DEGRANULATION ASSAY; ELECTRON MICROSCOPY; ENZYME INHIBITION; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOLOGICAL SYNAPSE; MOUSE; NATURAL KILLER CELL; NONHUMAN; POLARIZATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SPLEEN CELL; T LYMPHOCYTE ACTIVATION; VELOCITY; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; ANTIGEN PRESENTING CELL; BAGG ALBINO MOUSE; ENZYMOLOGY; GENE SILENCING; METABOLISM; PHYSIOLOGY;

ACTINS; ANIMALS; ANTIGEN-PRESENTING CELLS; CELL MEMBRANE; GENE KNOCKDOWN TECHNIQUES; IMMUNOLOGICAL SYNAPSES; MICE, INBRED BALB C; T-LYMPHOCYTES, CYTOTOXIC; ZAP-70 PROTEIN-TYROSINE KINASE;

EID: 84898731316     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.01310     Document Type: Article

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