The role of TLR4-mediated PTEN/PI3K/AKT/NF-κB signaling pathway in neuroinflammation in hippocampal neurons

Neuroscience

Volumn 269, Issue , 2014, Pages 93-101

  Zhao, M ^a   Zhou, A ^a   Xu, L ^a   Zhang, X ^a  

^a NANTONG UNIVERSITY   (China)

Author keywords

Hippocampal neurons; Neuroinflammation; PTEN; TLR4

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; IL1B PROTEIN, RAT; PTEN PROTEIN, RAT; TLR4 PROTEIN, RAT;

ANIMAL CELL; ARTICLE; BRAIN CELL CULTURE; BRAIN NERVE CELL; CELL STIMULATION; CELLULAR DISTRIBUTION; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DISEASE ASSOCIATION; DOWN REGULATION; ENZYME PHOSPHORYLATION; GENE EXPRESSION REGULATION; HIPPOCAMPUS; INTRACELLULAR SIGNALING; MOLECULAR DYNAMICS; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CELL NUCLEUS; DRUG EFFECTS; IMMUNOLOGY; IMMUNOMODULATION; METABOLISM; NERVE CELL; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ANIMALS; CELL NUCLEUS; CELLS, CULTURED; HIPPOCAMPUS; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; NEUROIMMUNOMODULATION; NEURONS; NF-KAPPA B; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84898685187     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2014.03.039     Document Type: Article

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