Nuclear trafficking of Pten after brain injury leads to neuron survival not death

Experimental Neurology

Volumn 252, Issue , 2014, Pages 37-46

  Goh, Choo Peng ^a   Putz, Ulrich ^a   Howitt, Jason ^a   Low, Ley Hian ^a   Gunnersen, Jenny ^a   Bye, Nicole ^b   Morganti Kossmann, Cristina ^b   Tan, Seong Seng ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b MONASH UNIVERSITY   (Australia)

Author keywords

Ndfip1; Nedd4; Neuroprotection; Pten; Traumatic brain injury; Ubiquitination

Indexed keywords

ADAPTOR PROTEIN; NEDD4 E3 LIGASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN NDFIP1; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN INJURY; BRAIN NERVE CELL; CELL COUNT; CELL NUCLEUS; CELL SURVIVAL; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; MALE; MOUSE; NERVE CELL NECROSIS; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; UBIQUITINATION;

NDFIP1; NEDD4; NEUROPROTECTION; PTEN; TRAUMATIC BRAIN INJURY; UBIQUITINATION;

ANALYSIS OF VARIANCE; ANIMALS; APOPTOSIS; BRAIN INJURIES; CARRIER PROTEINS; CELL NUCLEUS; CELL SURVIVAL; CYTOPLASM; DISEASE MODELS, ANIMAL; FUNCTIONAL LATERALITY; GENE EXPRESSION REGULATION; IMMUNOPRECIPITATION; IN SITU NICK-END LABELING; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEURONS; ONCOGENE PROTEIN V-AKT; PROTEIN TRANSPORT; PTEN PHOSPHOHYDROLASE;

EID: 84890081732     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2013.11.017     Document Type: Article

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