Clinical and prognostic significance of HIF-1α, PTEN, CD44v6, and survivin for gastric cancer: A meta-analysis

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Chen, Jing ^a   Li, Tao ^a   Liu, Qilun ^a   Jiao, Haiyan ^a   Yang, Wenjun ^a   Liu, Xiaoxia ^a   Huo, Zhenghao ^a  

^a NINGXIA MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CD44V6 ANTIGEN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; SURVIVIN; BIRC5 PROTEIN, HUMAN; HERMES ANTIGEN; HIF1A PROTEIN, HUMAN; INHIBITOR OF APOPTOSIS PROTEIN; PTEN PROTEIN, HUMAN;

ARTICLE; DISTANT METASTASIS; HUMAN; LYMPH NODE METASTASIS; OVERALL SURVIVAL; PROGNOSIS; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; SENSITIVITY ANALYSIS; STOMACH CANCER; TUMOR INVASION; TUMOR VOLUME; BIOLOGICAL MODEL; CELL HYPOXIA; FEMALE; MALE; META ANALYSIS; METABOLISM; METASTASIS; MIDDLE AGED; PATHOLOGY; PUBLISHING; STOMACH TUMOR; SURVIVAL;

ANTIGENS, CD44; CELL HYPOXIA; FEMALE; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INHIBITOR OF APOPTOSIS PROTEINS; MALE; MIDDLE AGED; MODELS, BIOLOGICAL; NEOPLASM METASTASIS; PROGNOSIS; PTEN PHOSPHOHYDROLASE; PUBLICATION BIAS; STOMACH NEOPLASMS; SURVIVAL ANALYSIS;

EID: 84898645524     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0091842     Document Type: Article

References (36)

1. Jemal A, Siegel R, Ward E, Hao Y, Xu J, et al. (2009) Cancer statistics, 2009. CA Cancer J Clin 59: 225-249.
2. Jemal A, Bray F, Center MM, Ferlay J, Ward E, et al. (2011) Global cancer statistics. CA Cancer J Clin 61: 69-90.
3. Valastyan S, Weinberg RA (2011) Tumor metastasis: molecular insights and evolving paradigms. Cell 147: 275-292.
4. Gupta GP, Massague J (2006) Cancer metastasis: building a framework. Cell 127: 679-695. (Pubitemid 44781029)
5. Lu X, Kang Y (2010) Hypoxia and hypoxia-inducible factors: master regulators of metastasis. Clin Cancer Res 16: 5928-5935.
6. Majmundar AJ, Wong WJ, Simon MC (2010) Hypoxia-inducible factors and the response to hypoxic stress. Mol Cell 40: 294-309.
7. Keith B, Johnson RS, Simon MC (2012) HIF1alpha and HIF2alpha: sibling rivalry in hypoxic tumour growth and progression. Nat Rev Cancer 12: 9-22.
8. Semenza GL (2003) Targeting HIF-1 for cancer therapy. Nat Rev Cancer 3: 721-732.
9. Semenza GL (2012) Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy. Trends Pharmacol Sci 33: 207-214.
10. Tsai YP, Wu KJ (2012) Hypoxia-regulated target genes implicated in tumor metastasis. J Biomed Sci 19: 102.
11. Moher D, Liberati A, Tetzlaff J, Altman DG (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med 6: e1000097.
12. McShane LM, Altman DG, Sauerbrei W, Taube SE, Gion M, et al. (2005) REporting recommendations for tumour MARKer prognostic studies (REMARK). Br J Cancer 93: 387-391. (Pubitemid 43080010)
13. Lau J, Ioannidis JP, Schmid CH (1997) Quantitative synthesis in systematic reviews. Ann Intern Med 127: 820-826. (Pubitemid 27465551)
14. Lou-Qian Z, Rong Y, Ming L, Xin Y, Feng J, et al. (2013) The prognostic value of epigenetic silencing of p16 gene in NSCLC patients: a systematic review and meta-analysis. PLoS One 8: e54970.
15. Shin HR, Carlos MC, Varghese C (2012) Cancer control in the Asia Pacific region: current status and concerns. Jpn J Clin Oncol 42: 867-881.
16. Shah MA, Khanin R, Tang L, Janjigian YY, Klimstra DS, et al. (2011) Molecular classification of gastric cancer: a new paradigm. Clin Cancer Res 17: 2693-2701.
17. Meza-Junco J, Sawyer MB (2012) Metastatic gastric cancer - focus on targeted therapies. Biologics 6: 137-146.
18. Hill RP, Marie-Egyptienne DT, Hedley DW (2009) Cancer stem cells, hypoxia and metastasis. Semin Radiat Oncol 19: 106-111.
19. Zhao T, Lv J, Zhao J, Nzekebaloudou M (2009) Hypoxia-inducible factor-1alpha gene polymorphisms and cancer risk: a meta-analysis. J Exp Clin Cancer Res 28: 159.
20. Park JH, Lee JY, Shin DH, Jang KS, Kim HJ, et al. (2011) Loss of Mel-18 induces tumor angiogenesis through enhancing the activity and expression of HIF-1alpha mediated by the PTEN/PI3K/Akt pathway. Oncogene 30: 4578-4589.
21. Krishnamachary B, Zagzag D, Nagasawa H, Rainey K, Okuyama H, et al. (2006) Hypoxia-inducible factor-1-dependent repression of E-cadherin in von Hippel-Lindau tumor suppressor-null renal cell carcinoma mediated by TCF3, ZFHX1A, and ZFHX1B. Cancer Res 66: 2725-2731.
22. Rohwer N, Cramer T (2011) Hypoxia-mediated drug resistance: novel insights on the functional interaction of HIFs and cell death pathways. Drug Resist Updat 14: 191-201.
23. Lanvin O, Monferran S, Delmas C, Couderc B, Toulas C, et al. (2013) Radiation-induced mitotic cell death and glioblastoma radioresistance: A new regulating pathway controlled by integrin-linked kinase, hypoxia-inducible factor 1alpha and survivin in U87 cells. Eur J Cancer.
24. Zheng SS, Chen XH, Yin X, Zhang BH (2013) Prognostic Significance of HIF-1alpha Expression in Hepatocellular Carcinoma: A Meta-Analysis. PLoS One 8: e65753.
25. Hanahan D, Weinberg RA (2011) Hallmarks of cancer: the next generation. Cell 144: 646-674.
26. Chen J, Wang J, Lin L, He L, Wu Y, et al. (2012) Inhibition of STAT3 signaling pathway by nitidine chloride suppressed the angiogenesis and growth of human gastric cancer. Mol Cancer Ther 11: 277-287.
27. Sullivan R, Graham CH (2007) Hypoxia-driven selection of the metastatic phenotype. Cancer Metastasis Rev 26: 319-331. (Pubitemid 47101665)
28. Krishnamachary B, Penet MF, Nimmagadda S, Mironchik Y, Raman V, et al. (2012) Hypoxia regulates CD44 and its variant isoforms through HIF-1alpha in triple negative breast cancer. PLoS One 7: e44078.
29. Sun XP, Dong X, Lin L, Jiang X, Wei Z, et al. (2014) Up-regulation of survivin by AKT and hypoxia-inducible factor 1alpha contributes to cisplatin resistance in gastric cancer. FEBS J 281: 115-128.
30. Zhu CL, Huang Q, Liu CH, Lin XS, Xie F (2013) Prognostic value of HIF-1alpha expression in patients with gastric cancer. Mol Biol Rep 40: 6055-6062.
31. Zhang ZG, Zhang QN, Wang XH, Tian JH (2013) Hypoxia-inducible factor 1 alpha (HIF-1alpha) as a prognostic indicator in patients with gastric tumors: a meta-analysis. Asian Pac J Cancer Prev 14: 4195-4198.
32. Liu JL, Gao W, Kang QM, Zhang XJ, Yang SG (2013) Prognostic value of survivin in patients with gastric cancer: a systematic review with meta-analysis. PLoS One 8: e71930.
33. Krieg A, Baseras B, Tomczak M, Verde PE, Stoecklein NH, et al. (2013) Role of survivin as prognostic and clinicopathological marker in gastric cancer: a meta-analysis. Mol Biol Rep 40: 5501-5511.
34. Hayes DF, Isaacs C, Stearns V (2001) Prognostic factors in breast cancer: current and new predictors of metastasis. J Mammary Gland Biol Neoplasia 6: 375-392.
35. Chen J, Li T, Wu Y, He L, Zhang L, et al. (2011) Prognostic significance of vascular endothelial growth factor expression in gastric carcinoma: a meta-analysis. J Cancer Res Clin Oncol 137: 1799-1812.
36. Ocana A, Vera-Badillo F, Seruga B, Templeton A, Pandiella A, et al. (2013) HER3 overexpression and survival in solid tumors: a meta-analysis. J Natl Cancer Inst 105: 266-273.