메뉴 건너뛰기




Volumn 77, Issue , 2013, Pages 1-15

Arginine and asthma

Author keywords

[No Author keywords available]

Indexed keywords

ARGINASE; ARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

EID: 84898629204     PISSN: 16642147     EISSN: 16642155     Source Type: Book Series    
DOI: 10.1159/000351365     Document Type: Conference Paper
Times cited : (13)

References (74)
  • 3
    • 80054887543 scopus 로고    scopus 로고
    • The biochemistry of asthma
    • Gaston B: The biochemistry of asthma. Biochim Biophys Acta 2011; 1810: 1017-1024.
    • (2011) Biochim Biophys Acta , vol.1810 , pp. 1017-1024
    • Gaston, B.1
  • 4
    • 2342482002 scopus 로고    scopus 로고
    • Nitric oxide in health and disease of the respiratory system
    • Ricciardolo FL, Sterk PJ, Gaston B, et al: Nitric oxide in health and disease of the respiratory system. Physiol Rev 2004; 84: 731-765.
    • (2004) Physiol Rev , vol.84 , pp. 731-765
    • Ricciardolo, F.L.1    Sterk, P.J.2    Gaston, B.3
  • 5
    • 33644781595 scopus 로고    scopus 로고
    • Modulation of nitric oxide pathways: Therapeutic potential in asthma and chronic obstructive pulmonary disease
    • Redington AE: Modulation of nitric oxide pathways: therapeutic potential in asthma and chronic obstructive pulmonary disease. Eur J Pharmacol 2006; 533: 263-276.
    • (2006) Eur J Pharmacol , vol.533 , pp. 263-276
    • Redington, A.E.1
  • 6
    • 0031900026 scopus 로고    scopus 로고
    • Correlation between exhaled nitric oxide, sputum eosinophils, and methacholine responsiveness in patients with mild asthma
    • Jatakanon A, Lim S, Kharitonov S, et al: Correlation between exhaled nitric oxide, sputum eosinophils, and methacholine responsiveness in patients with mild asthma. Thorax 1998; 53: 91-95.
    • (1998) Thorax , vol.53 , pp. 91-95
    • Jatakanon, A.1    Lim, S.2    Kharitonov, S.3
  • 7
    • 0034864110 scopus 로고    scopus 로고
    • Role of nitric oxide and superoxide in allergen-induced airway hyperreactivity after the late asthmatic reaction in guinea-pigs
    • de Boer J, Meurs H, Flendrig L, et al: Role of nitric oxide and superoxide in allergen-induced airway hyperreactivity after the late asthmatic reaction in guinea-pigs. Br J Pharmacol 2001; 133: 1235-1242.
    • (2001) Br J Pharmacol , vol.133 , pp. 1235-1242
    • De Boer, J.1    Meurs, H.2    Flendrig, L.3
  • 8
    • 69249138275 scopus 로고    scopus 로고
    • Larginine deficiency causes airway hyperresponsiveness after the late asthmatic reaction
    • Maarsingh H, Bossenga BE, Bos IS, et al: Larginine deficiency causes airway hyperresponsiveness after the late asthmatic reaction. Eur Respir J 2009; 34: 191-199.
    • (2009) Eur Respir J , vol.34 , pp. 191-199
    • Maarsingh, H.1    Bossenga, B.E.2    Bos, I.S.3
  • 9
    • 37149036630 scopus 로고    scopus 로고
    • Transiently, paralleled upregulation of arginase and nitric oxide synthase and the effect of both enzymes on the pathology of asthma
    • Takemoto K, Ogino K, Shibamori M, et al: Transiently, paralleled upregulation of arginase and nitric oxide synthase and the effect of both enzymes on the pathology of asthma. Am J Physiol Lung Cell Mol Physiol 2007; 293:L1419-L1426.
    • (2007) Am J Physiol Lung Cell Mol Physiol , vol.293 , pp. L1419-L1426
    • Takemoto, K.1    Ogino, K.2    Shibamori, M.3
  • 10
    • 33644852813 scopus 로고    scopus 로고
    • Arginine: Beyond protein
    • Morris SM Jr: Arginine: beyond protein. Am J Clin Nutr 2006; 83: 508S-512S.
    • (2006) Am J Clin Nutr , vol.83 , pp. 508S-512S
    • Morris, S.M.1
  • 11
    • 3142757008 scopus 로고    scopus 로고
    • Decreased arginine bioavailability and increased arginase activity in asthma
    • Morris CR, Poljakovic M, Lavisha L, et al: Decreased arginine bioavailability and increased arginase activity in asthma. Am J Respir Crit Care Med 2004; 170: 148-153.
    • (2004) Am J Respir Crit Care Med , vol.170 , pp. 148-153
    • Morris, C.R.1    Poljakovic, M.2    Lavisha, L.3
  • 12
    • 52749084926 scopus 로고    scopus 로고
    • Alterations of the arginine metabolome in asthma
    • Lara A, Khatri SB, Wang Z, et al: Alterations of the arginine metabolome in asthma. Am J Respir Crit Care Med 2008; 178: 673-681.
    • (2008) Am J Respir Crit Care Med , vol.178 , pp. 673-681
    • Lara, A.1    Khatri, S.B.2    Wang, Z.3
  • 13
    • 0032533159 scopus 로고    scopus 로고
    • Arginine metabolism: Nitric oxide and beyond
    • Wu G, Morris SM: Arginine metabolism: nitric oxide and beyond. Biochem J 1998; 336: 1-17.
    • (1998) Biochem J , vol.336 , pp. 1-17
    • Wu, G.1    Morris, S.M.2
  • 14
    • 64549106465 scopus 로고    scopus 로고
    • Asthma management: Reinventing the wheel in sickle cell disease
    • Morris CR: Asthma management: reinventing the wheel in sickle cell disease. Am J Hematol 2009; 84: 234-241.
    • (2009) Am J Hematol , vol.84 , pp. 234-241
    • Morris, C.R.1
  • 15
    • 21444441271 scopus 로고    scopus 로고
    • Dysregulated arginine metabolism, hemolysisassociated pulmonary hypertension and mortality in sickle cell disease
    • Morris CR, Kato GJ, Poljakovic M, et al: Dysregulated arginine metabolism, hemolysisassociated pulmonary hypertension and mortality in sickle cell disease. JAMA 2005; 294: 81-90.
    • (2005) JAMA , vol.294 , pp. 81-90
    • Morris, C.R.1    Kato, G.J.2    Poljakovic, M.3
  • 16
    • 65949124657 scopus 로고    scopus 로고
    • Mechanisms of vasculopathy in sickle cell disease and thalassemia
    • Morris CR: Mechanisms of vasculopathy in sickle cell disease and thalassemia. Hematology Am Soc Hematol Educ Program 2008; 2008: 177-185.
    • (2008) Hematology Am Soc Hematol Educ Program , vol.2008 , pp. 177-185
    • Morris, C.R.1
  • 17
    • 46949111065 scopus 로고    scopus 로고
    • Arginases i and II in lungs of ovalbumin-sensitized mice exposed to ovalbumin: Source and consequences
    • Kenyon NJ, Bratt JM, Linderholm AL, et al: Arginases I and II in lungs of ovalbumin-sensitized mice exposed to ovalbumin: source and consequences. Toxicol Appl Pharmacol 2008; 230: 269-275.
    • (2008) Toxicol Appl Pharmacol , vol.230 , pp. 269-275
    • Kenyon, N.J.1    Bratt, J.M.2    Linderholm, A.L.3
  • 18
    • 25444448497 scopus 로고    scopus 로고
    • Arginase attenuates inhibitory nonadrenergic noncholinergic nerve-induced nitric oxide generation and airway smooth muscle relaxation
    • Maarsingh H, Tio MA, Zaagsma J, et al: Arginase attenuates inhibitory nonadrenergic noncholinergic nerve-induced nitric oxide generation and airway smooth muscle relaxation. Respir Res 2005; 6: 23.
    • (2005) Respir Res , vol.6 , pp. 23
    • Maarsingh, H.1    Tio, M.A.2    Zaagsma, J.3
  • 19
    • 84872948871 scopus 로고    scopus 로고
    • Antiinflammatory effect of arginase inhibitor and corticosteroid on airway allergic reactions in a Dermatophogoides farinae-induced NC/Nga mouse model
    • Ogino K, Kubo M, Takahashi H, et al: Antiinflammatory effect of arginase inhibitor and corticosteroid on airway allergic reactions in a Dermatophogoides farinae-induced NC/Nga mouse model. Inflammation 2013; 36: 141-151.
    • (2013) Inflammation , vol.36 , pp. 141-151
    • Ogino, K.1    Kubo, M.2    Takahashi, H.3
  • 20
    • 0036016110 scopus 로고    scopus 로고
    • Increased arginase activity underlies allergeninduced deficiency of cNOS-derived nitric oxide and airway hyperresponsiveness
    • Meurs H, McKay S, Maarsingh H, et al: Increased arginase activity underlies allergeninduced deficiency of cNOS-derived nitric oxide and airway hyperresponsiveness. Br J Pharmacol 2002; 136: 391-398.
    • (2002) Br J Pharmacol , vol.136 , pp. 391-398
    • Meurs, H.1    McKay, S.2    Maarsingh, H.3
  • 21
    • 32844458380 scopus 로고    scopus 로고
    • Arginase strongly impairs neuronal nitric oxidemediated airway smooth muscle relaxation in allergic asthma
    • Maarsingh H, Leusink J, Bos ISS, et al: Arginase strongly impairs neuronal nitric oxidemediated airway smooth muscle relaxation in allergic asthma. Respir Res 2006; 7: 6.
    • (2006) Respir Res , vol.7 , pp. 6
    • Maarsingh, H.1    Leusink, J.2    Bos, I.S.S.3
  • 22
    • 51849107399 scopus 로고    scopus 로고
    • Arginase inhibition protects against allergic airway obstruction, hyperreponsiveness and inflammation
    • Maarsingh H, Zuidhof AB, Bos IS, et al: Arginase inhibition protects against allergic airway obstruction, hyperreponsiveness and inflammation. Am J Respir Crit Care Med 2008; 178: 565-573.
    • (2008) Am J Respir Crit Care Med , vol.178 , pp. 565-573
    • Maarsingh, H.1    Zuidhof, A.B.2    Bos, I.S.3
  • 23
    • 58649121269 scopus 로고    scopus 로고
    • Arginase enzymes in isolated airways from normal and nitric oxide synthase 2-knockout mice exposed to ovalbumin
    • Bratt JM, Franzi LM, Linderholm AL, et al: Arginase enzymes in isolated airways from normal and nitric oxide synthase 2-knockout mice exposed to ovalbumin. Toxicol Appl Pharmacol 2009; 234: 273-280.
    • (2009) Toxicol Appl Pharmacol , vol.234 , pp. 273-280
    • Bratt, J.M.1    Franzi, L.M.2    Linderholm, A.L.3
  • 24
    • 56149107742 scopus 로고    scopus 로고
    • Inhibition of arginase activity enhances inflammation in mice with allergic airway disease, in association with increases in protein-S nitrosylation and tyrosine nitration
    • Ckless K, Lampert A, Reiss J, et al: Inhibition of arginase activity enhances inflammation in mice with allergic airway disease, in association with increases in protein-S nitrosylation and tyrosine nitration. J Immunol 2008; 181: 4255-4264.
    • (2008) J Immunol , vol.181 , pp. 4255-4264
    • Ckless, K.1    Lampert, A.2    Reiss, J.3
  • 25
    • 67649604532 scopus 로고    scopus 로고
    • Bone marrow cell derived arginase i is the major source of allergen-induced lung arginase but is not required for airway hyperresponsiveness, remodeling and lung inflammatory responses in mice
    • Niese KA, Collier AR, Hajek AR, et al: Bone marrow cell derived arginase I is the major source of allergen-induced lung arginase but is not required for airway hyperresponsiveness, remodeling and lung inflammatory responses in mice. BMC Immunol 2009; 10: 33.
    • (2009) BMC Immunol , vol.10 , pp. 33
    • Niese, K.A.1    Collier, A.R.2    Hajek, A.R.3
  • 26
    • 0028985126 scopus 로고
    • Inhibition of arginase by N-G-hydroxy-L-arginine in alveolar macrophages-implications for the utilization of L-arginine for nitric oxide synthesis
    • Hecker M, Nematollahi H, Hey C, et al: Inhibition of arginase by N-G-hydroxy-L-arginine in alveolar macrophages-implications for the utilization of L-arginine for nitric oxide synthesis. FEBS Lett 1995; 359: 251-254.
    • (1995) FEBS Lett , vol.359 , pp. 251-254
    • Hecker, M.1    Nematollahi, H.2    Hey, C.3
  • 27
    • 43049133045 scopus 로고    scopus 로고
    • L-ornithine causes NO deficiency and airway hyperresponsiveness in perfused guinea pig tracheal preparations in vitro
    • Maarsingh H, Volders HH, Zaagsma J, et al: L-ornithine causes NO deficiency and airway hyperresponsiveness in perfused guinea pig tracheal preparations in vitro. Naunyn-Schmiedbergs Arch Pharmacol 2007; 375: 151.
    • (2007) Naunyn-Schmiedbergs Arch Pharmacol , vol.375 , pp. 151
    • Maarsingh, H.1    Volders, H.H.2    Zaagsma, J.3
  • 28
    • 0028102802 scopus 로고
    • Constitutive and inducible nitric oxide synthase gene expression, regulation, and activity in human lung epithelial cells
    • Asano K, Chee CB, Gaston B, et al: Constitutive and inducible nitric oxide synthase gene expression, regulation, and activity in human lung epithelial cells. Proc Natl Acad Sci USA 1994; 91: 10089-10093.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 10089-10093
    • Asano, K.1    Chee, C.B.2    Gaston, B.3
  • 29
    • 0027379178 scopus 로고
    • Induction of nitric oxide synthase in asthma
    • Hamid Q, Springall DR, Riveros-Moreno V, et al: Induction of nitric oxide synthase in asthma. Lancet 1993; 342: 1510-1513.
    • (1993) Lancet , vol.342 , pp. 1510-1513
    • Hamid, Q.1    Springall, D.R.2    Riveros-Moreno, V.3
  • 30
    • 0028916297 scopus 로고    scopus 로고
    • Reciprocal regulation of the nitric oxide synthase/ arginase balance in mouse bone marrow-derived macrophages by TH1 and TH2 cytokines
    • Modolell M, Corraliza IM, Link F, et al: Reciprocal regulation of the nitric oxide synthase/ arginase balance in mouse bone marrow-derived macrophages by TH1 and TH2 cytokines. Eur J Immunol 2005; 25: 1101-1104.
    • (2005) Eur J Immunol , vol.25 , pp. 1101-1104
    • Modolell, M.1    Corraliza, I.M.2    Link, F.3
  • 31
    • 0042243556 scopus 로고    scopus 로고
    • Dissection of experimental asthma with DNA microarray analysis identifies arginase in asthma pathogenesis
    • Zimmermann N, King NE, Laporte J, et al: Dissection of experimental asthma with DNA microarray analysis identifies arginase in asthma pathogenesis. J Clin Invest 2003; 111: 1863-1874.
    • (2003) J Clin Invest , vol.111 , pp. 1863-1874
    • Zimmermann, N.1    King, N.E.2    Laporte, J.3
  • 32
    • 69249138275 scopus 로고    scopus 로고
    • L-arginine deficiency causes airway hyperresponsiveness after the late asthmatic reaction
    • Maarsingh H, Bossenga BE, Bos IST, et al: L-arginine deficiency causes airway hyperresponsiveness after the late asthmatic reaction. Eur Respir J 2009; 34: 191-199.
    • (2009) Eur Respir J , vol.34 , pp. 191-199
    • Maarsingh, H.1    Bossenga, B.E.2    Bos, I.S.T.3
  • 33
    • 67049156045 scopus 로고    scopus 로고
    • Functionally important role for arginase 1 in the airway hyperresponsiveness of asthma
    • North ML, Khanna N, Marsden PA, et al: Functionally important role for arginase 1 in the airway hyperresponsiveness of asthma. Am J Physiol Lung Cell Mol Physiol 2009; 296:L911-L920.
    • (2009) Am J Physiol Lung Cell Mol Physiol , vol.296 , pp. L911-L920
    • North, M.L.1    Khanna, N.2    Marsden, P.A.3
  • 34
    • 33644872983 scopus 로고    scopus 로고
    • Effects of inducible nitric oxide synthase inhibitors on asthma depending on administration schedule
    • Abe M, Hayashi Y, Murai A, et al: Effects of inducible nitric oxide synthase inhibitors on asthma depending on administration schedule. Free Radic Biol Med 2006; 40: 1083-1095.
    • (2006) Free Radic Biol Med , vol.40 , pp. 1083-1095
    • Abe, M.1    Hayashi, Y.2    Murai, A.3
  • 35
    • 33749531372 scopus 로고    scopus 로고
    • Inhibition of arginase i activity by RNA interference attenuates IL-13-induced airways hyperresponsiveness
    • Yang M, Rangasamy D, Matthaei KI, et al: Inhibition of arginase I activity by RNA interference attenuates IL-13-induced airways hyperresponsiveness. J Immunol 2006; 177: 5595-5603.
    • (2006) J Immunol , vol.177 , pp. 5595-5603
    • Yang, M.1    Rangasamy, D.2    Matthaei, K.I.3
  • 36
    • 0042243556 scopus 로고    scopus 로고
    • Dissection of experimental asthma with DNA microarray analysis identifies arginase in asthma pathogenesis
    • Zimmerman N, King NE, Laporte J, et al: Dissection of experimental asthma with DNA microarray analysis identifies arginase in asthma pathogenesis. J Clin Invest 2003; 111: 1863-1874.
    • (2003) J Clin Invest , vol.111 , pp. 1863-1874
    • Zimmerman, N.1    King, N.E.2    Laporte, J.3
  • 37
    • 0141989767 scopus 로고    scopus 로고
    • Global gene expression profiles during acute pathogen-induced pulmonary inflammation reveal divergent roles for Th1 and Th2 reponses in tissue repair
    • Sandler NG, Mentink-Kane MM, Cheever AW, et al: Global gene expression profiles during acute pathogen-induced pulmonary inflammation reveal divergent roles for Th1 and Th2 reponses in tissue repair. J Immunol 2003; 171: 3655-3667.
    • (2003) J Immunol , vol.171 , pp. 3655-3667
    • Sandler, N.G.1    Mentink-Kane, M.M.2    Cheever, A.W.3
  • 38
    • 39849086012 scopus 로고    scopus 로고
    • Diseasespecific gene expression profiling in multiple models of lung disease
    • Lewis CC, Yang JY, Huang X, et al: Diseasespecific gene expression profiling in multiple models of lung disease. Am J Respir Crit Care Med 2007; 177: 376-387.
    • (2007) Am J Respir Crit Care Med , vol.177 , pp. 376-387
    • Lewis, C.C.1    Yang, J.Y.2    Huang, X.3
  • 39
    • 84862862603 scopus 로고    scopus 로고
    • Pollutant particles induce arginase II in human bronchial epithelial cells
    • Hyseni X, Soukup JM, Huang YC: Pollutant particles induce arginase II in human bronchial epithelial cells. J Toxicol Environ Health A 2012; 75: 624-636.
    • (2012) J Toxicol Environ Health A , vol.75 , pp. 624-636
    • Hyseni, X.1    Soukup, J.M.2    Huang, Y.C.3
  • 40
    • 80051556100 scopus 로고    scopus 로고
    • DNA methylation in the arginase-nitric oxide synthase pathway is associated with exhaled nitric oxide in children with asthma
    • Breton CV, Byun HM, Wang X, et al: DNA methylation in the arginase-nitric oxide synthase pathway is associated with exhaled nitric oxide in children with asthma. Am J Respir Crit Care Med 2011; 184: 191-197.
    • (2011) Am J Respir Crit Care Med , vol.184 , pp. 191-197
    • Breton, C.V.1    Byun, H.M.2    Wang, X.3
  • 41
    • 17444446032 scopus 로고
    • Sputum arginase activity in bronchial asthma
    • Kochanski L, Kossmann S, Rogala E, et al: Sputum arginase activity in bronchial asthma. Pneumonol Pol 1980; 48: 329-332.
    • (1980) Pneumonol Pol , vol.48 , pp. 329-332
    • Kochanski, L.1    Kossmann, S.2    Rogala, E.3
  • 42
    • 67049156045 scopus 로고    scopus 로고
    • Functionally important role for arginase 1 in the airway hyperresponsiveness of asthma
    • North ML, Khanna N, Marsden PA, et al: Functionally important role for arginase 1 in the airway hyperresponsiveness of asthma. Am J Physiol Lung Cell Mol Physiol 2009; 296:L911-L920.
    • (2009) Am J Physiol Lung Cell Mol Physiol , vol.296 , pp. L911-L920
    • North, M.L.1    Khanna, N.2    Marsden, P.A.3
  • 43
    • 29644436252 scopus 로고    scopus 로고
    • Genetic polymorphisms in arginase i and II and childhood asthma and atopy
    • Li H, Romieu I, Sienra-Monge J-J, et al: Genetic polymorphisms in arginase I and II and childhood asthma and atopy. J Allergy Clin Immunol 2006; 117: 119-126.
    • (2006) J Allergy Clin Immunol , vol.117 , pp. 119-126
    • Li, H.1    Romieu, I.2    Sienra-Monge, J.-J.3
  • 44
    • 0043204998 scopus 로고    scopus 로고
    • Arginine therapy: A new treatment for pulmonary hypertension in sickle cell disease?
    • Morris CR, Morris SM Jr, Hagar W, et al: Arginine therapy: a new treatment for pulmonary hypertension in sickle cell disease? Am J Respir Crit Care Med 2003; 168: 63-69.
    • (2003) Am J Respir Crit Care Med , vol.168 , pp. 63-69
    • Morris, C.R.1    Morris, S.M.2    Hagar, W.3
  • 45
    • 80051531018 scopus 로고    scopus 로고
    • Increased arginase activity contributes to airway remodelling in chronic allergic asthma
    • Maarsingh H, Dekkers BG, Zuidhof AB, et al: Increased arginase activity contributes to airway remodelling in chronic allergic asthma. Eur Respir J 2011; 38: 318-328.
    • (2011) Eur Respir J , vol.38 , pp. 318-328
    • Maarsingh, H.1    Dekkers, B.G.2    Zuidhof, A.B.3
  • 46
    • 0034038624 scopus 로고    scopus 로고
    • In rat alveolar macrophages lipopolysaccharides exert divergent effects on the transport of the cationic amino acids Larginine and L-ornithine
    • Messeri-Dreissig MD, Hammermann R, Mossner J, et al: In rat alveolar macrophages lipopolysaccharides exert divergent effects on the transport of the cationic amino acids Larginine and L-ornithine. Naunyn-Schmiedbergs Arch Pharmacol 2000; 361: 621-628.
    • (2000) Naunyn-Schmiedbergs Arch Pharmacol , vol.361 , pp. 621-628
    • Messeri-Dreissig, M.D.1    Hammermann, R.2    Mossner, J.3
  • 47
    • 0026560972 scopus 로고
    • L-arginine transport is increased in macrophages generating nitric oxide
    • Bogle RG, Baydoun AR, Pearson JD, et al: L-arginine transport is increased in macrophages generating nitric oxide. Biochem J 1992; 284: 15-18.
    • (1992) Biochem J , vol.284 , pp. 15-18
    • Bogle, R.G.1    Baydoun, A.R.2    Pearson, J.D.3
  • 48
    • 0033172721 scopus 로고    scopus 로고
    • Cationic proteins inhibit L-arginine uptake in rat alveolar macrophages and tracheal epithelial cells. Implications for nitric oxide synthesis
    • Hammermann R, Hirschmann J, Hey C, et al: Cationic proteins inhibit L-arginine uptake in rat alveolar macrophages and tracheal epithelial cells. Implications for nitric oxide synthesis. Am J Respir Cell Mol Biol 1999; 21: 155-162.
    • (1999) Am J Respir Cell Mol Biol , vol.21 , pp. 155-162
    • Hammermann, R.1    Hirschmann, J.2    Hey, C.3
  • 49
    • 0035844305 scopus 로고    scopus 로고
    • Sustained nitric oxide production in macrophages requires the arginine transporter CAT2
    • Nicholson B, Manner CK, Kleeman J, et al: Sustained nitric oxide production in macrophages requires the arginine transporter CAT2. J Biol Chem 2001; 276: 15881-15885.
    • (2001) J Biol Chem , vol.276 , pp. 15881-15885
    • Nicholson, B.1    Manner, C.K.2    Kleeman, J.3
  • 50
    • 0344406171 scopus 로고    scopus 로고
    • CAT2 arginine transporter deficiency significantly reduces iNOS-mediated NO production in astrocytes
    • Manner CK, Nicholson B, MacLeod CL: CAT2 arginine transporter deficiency significantly reduces iNOS-mediated NO production in astrocytes. J Neurochem 2003; 85: 476-482.
    • (2003) J Neurochem , vol.85 , pp. 476-482
    • Manner, C.K.1    Nicholson, B.2    Macleod, C.L.3
  • 51
    • 0032134205 scopus 로고    scopus 로고
    • L-arginine uptake and metabolism by lung macrophages and neutrophils following intratracheal instillation of silica in vivo
    • Schapira RM, Wiessner JH, Morrisey JF, et al: L-arginine uptake and metabolism by lung macrophages and neutrophils following intratracheal instillation of silica in vivo. Am J Respir Cell Mol Biol 1998; 19: 308-315.
    • (1998) Am J Respir Cell Mol Biol , vol.19 , pp. 308-315
    • Schapira, R.M.1    Wiessner, J.H.2    Morrisey, J.F.3
  • 52
    • 0033055177 scopus 로고    scopus 로고
    • Deficiency of nitric oxide in polycationinduced airway hyperreactivity
    • Meurs H, Schuurman FE, Duyvendak M, et al: Deficiency of nitric oxide in polycationinduced airway hyperreactivity. Br J Pharmacol 1999; 126: 559-562.
    • (1999) Br J Pharmacol , vol.126 , pp. 559-562
    • Meurs, H.1    Schuurman, F.E.2    Duyvendak, M.3
  • 53
    • 0037005735 scopus 로고    scopus 로고
    • Modulation of airway responsiveness by anionic and cationic polyelectrolyte substances
    • Yahata T, Nishimura Y, Maeda H, et al: Modulation of airway responsiveness by anionic and cationic polyelectrolyte substances. Eur J Pharmacol 2002; 434: 71-79.
    • (2002) Eur J Pharmacol , vol.434 , pp. 71-79
    • Yahata, T.1    Nishimura, Y.2    Maeda, H.3
  • 54
    • 0029947570 scopus 로고    scopus 로고
    • Peroxynitrite induces airway hyperresponsiveness in guinea pigs in vitro and in vivo
    • Sadeghi-Hashjin G, Folkerts G, Henricks PAJ, et al: Peroxynitrite induces airway hyperresponsiveness in guinea pigs in vitro and in vivo. Am J Respir Crit Care Med 1996; 153: 1697-1701.
    • (1996) Am J Respir Crit Care Med , vol.153 , pp. 1697-1701
    • Sadeghi-Hashjin, G.1    Folkerts, G.2    Henricks, P.A.J.3
  • 55
    • 0032788469 scopus 로고    scopus 로고
    • Role of peroxynitrite in airway microvascular hyperpermeability during late allergic phase in guinea pigs
    • Sugiura H, Ichinose M, Oyake T, et al: Role of peroxynitrite in airway microvascular hyperpermeability during late allergic phase in guinea pigs. Am J Respir Crit Care Med 1999; 160: 663-671.
    • (1999) Am J Respir Crit Care Med , vol.160 , pp. 663-671
    • Sugiura, H.1    Ichinose, M.2    Oyake, T.3
  • 56
    • 0031857283 scopus 로고    scopus 로고
    • Increased formation of the potent oxidant peroxynitrite in the airways of asthmatic patients is associated with induction of nitric oxide synthase: Effect of inhaled glucocorticoid
    • Saleh D, Ernst P, Lim S, et al: Increased formation of the potent oxidant peroxynitrite in the airways of asthmatic patients is associated with induction of nitric oxide synthase: effect of inhaled glucocorticoid. FASEB J 1998; 12: 929-937.
    • (1998) FASEB J , vol.12 , pp. 929-937
    • Saleh, D.1    Ernst, P.2    Lim, S.3
  • 58
    • 0032575598 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase generates superoxide anion from the reductase domain
    • Xia Y, Roman LJ, Masters BS, et al: Inducible nitric oxide synthase generates superoxide anion from the reductase domain. J Biol Chem 1998; 273: 22635-22639.
    • (1998) J Biol Chem , vol.273 , pp. 22635-22639
    • Xia, Y.1    Roman, L.J.2    Masters, B.S.3
  • 59
    • 80053411528 scopus 로고    scopus 로고
    • Asymmetric dimethylarginine is increased in asthma
    • Scott JA, North ML, Rafii M, et al: Asymmetric dimethylarginine is increased in asthma. Am J Respir Crit Care Med 2011; 184: 779-785.
    • (2011) Am J Respir Crit Care Med , vol.184 , pp. 779-785
    • Scott, J.A.1    North, M.L.2    Rafii, M.3
  • 60
    • 84868089090 scopus 로고    scopus 로고
    • ADMA, SDMA, L-arginine and nitric oxide in allergic pediatric bronchial asthma
    • Riccioni G, Bucciarelli V, Verini M, et al: ADMA, SDMA, L-arginine and nitric oxide in allergic pediatric bronchial asthma. J Biol Regul Homeost Agents 2012; 26: 561-566.
    • (2012) J Biol Regul Homeost Agents , vol.26 , pp. 561-566
    • Riccioni, G.1    Bucciarelli, V.2    Verini, M.3
  • 61
    • 0031897221 scopus 로고    scopus 로고
    • Effect of inhaled L-arginine on exhaled nitric oxide in normal and asthmatic subjects
    • Sapienza MA, Kharitonov SA, Horvath I, et al: Effect of inhaled L-arginine on exhaled nitric oxide in normal and asthmatic subjects. Thorax 1998; 53: 172-175.
    • (1998) Thorax , vol.53 , pp. 172-175
    • Sapienza, M.A.1    Kharitonov, S.A.2    Horvath, I.3
  • 62
    • 0032755339 scopus 로고    scopus 로고
    • Role of L-arginine in the deficiency of nitric oxide and airway hyperreactivity after the allergen-induced early asthmatic reaction in guinea pigs
    • deBoer J, Duyvendak M, Schuurman FE, et al: Role of L-arginine in the deficiency of nitric oxide and airway hyperreactivity after the allergen-induced early asthmatic reaction in guinea pigs. Br J Pharmacol 1999; 128: 1114-1120.
    • (1999) Br J Pharmacol , vol.128 , pp. 1114-1120
    • Deboer, J.1    Duyvendak, M.2    Schuurman, F.E.3
  • 63
    • 33749240002 scopus 로고    scopus 로고
    • Effects of nitric oxide synthases in chronic allergic airway inflammation and remodeling
    • Prado CM, Leick-Maldonado EA, Yano L, et al: Effects of nitric oxide synthases in chronic allergic airway inflammation and remodeling. Am J Respir Cell Mol Biol 2006; 35: 457-465.
    • (2006) Am J Respir Cell Mol Biol , vol.35 , pp. 457-465
    • Prado, C.M.1    Leick-Maldonado, E.A.2    Yano, L.3
  • 64
    • 78650016927 scopus 로고    scopus 로고
    • L-arginine reduces mitochondrial dysfunction and airway injury in murine allergic airway inflammation
    • Mabalirajan U, Ahmad T, Leishangthem GD, et al: L-arginine reduces mitochondrial dysfunction and airway injury in murine allergic airway inflammation. Int Immunopharmacol 2010; 10: 1514-1519.
    • (2010) Int Immunopharmacol , vol.10 , pp. 1514-1519
    • Mabalirajan, U.1    Ahmad, T.2    Leishangthem, G.D.3
  • 65
    • 77649275723 scopus 로고    scopus 로고
    • Beneficial effects of high dose of L-arginine on airway hyperresponsiveness and airway inflammation in a murine model of asthma
    • Mabalirajan U, Ahmad T, Leishangthem GD, et al: Beneficial effects of high dose of L-arginine on airway hyperresponsiveness and airway inflammation in a murine model of asthma. J Allergy Clin Immunol 2010; 125: 626-635.
    • (2010) J Allergy Clin Immunol , vol.125 , pp. 626-635
    • Mabalirajan, U.1    Ahmad, T.2    Leishangthem, G.D.3
  • 66
    • 33745761197 scopus 로고    scopus 로고
    • Inhaled Larginine improves exhaled nitric oxide and pulmonary function in patients with cystic fibrosis
    • Grasemann H, Kurtz F, Ratjen F: Inhaled Larginine improves exhaled nitric oxide and pulmonary function in patients with cystic fibrosis. Am J Respir Crit Care Med 2006; 174: 208-212.
    • (2006) Am J Respir Crit Care Med , vol.174 , pp. 208-212
    • Grasemann, H.1    Kurtz, F.2    Ratjen, F.3
  • 67
    • 0034906231 scopus 로고    scopus 로고
    • Effect of nebulised L-and D-arginine on exhaled nitric oxide in steroid naive asthma
    • Chambers DC, Ayres JG: Effect of nebulised L-and D-arginine on exhaled nitric oxide in steroid naive asthma. Thorax 2001; 56: 602-606.
    • (2001) Thorax , vol.56 , pp. 602-606
    • Chambers, D.C.1    Ayres, J.G.2
  • 68
    • 0032442107 scopus 로고    scopus 로고
    • Oral administration of L-arginine potentiates allergen-induced airway inflammation and expression of interleukin-5 in mice
    • Takano H, Lim HB, Miyabara Y, et al: Oral administration of L-arginine potentiates allergen-induced airway inflammation and expression of interleukin-5 in mice. J Pharmacol Exp Ther 1998; 286: 767-771.
    • (1998) J Pharmacol Exp Ther , vol.286 , pp. 767-771
    • Takano, H.1    Lim, H.B.2    Miyabara, Y.3
  • 69
    • 36348992469 scopus 로고    scopus 로고
    • Effects of L-arginine and phosphodiesterase-5 inhibitor, sildenafil, on inflammation and airway responsiveness of sensitized BP2 mice
    • Al Qadi-Nassar B, Bichon-Laurent F, Portet K, et al: Effects of L-arginine and phosphodiesterase-5 inhibitor, sildenafil, on inflammation and airway responsiveness of sensitized BP2 mice. Fundam Clin Pharmacol 2007; 21: 611-620.
    • (2007) Fundam Clin Pharmacol , vol.21 , pp. 611-620
    • Al Qadi-Nassar, B.1    Bichon-Laurent, F.2    Portet, K.3
  • 70
    • 0032721459 scopus 로고    scopus 로고
    • Effect of oral L-arginine on airway hyperresponsiveness to histamine in asthma
    • de Gouw HW, Verbruggen MB, Twiss IM, et al: Effect of oral L-arginine on airway hyperresponsiveness to histamine in asthma. Thorax 1999; 54: 1033-1035.
    • (1999) Thorax , vol.54 , pp. 1033-1035
    • De Gouw, H.W.1    Verbruggen, M.B.2    Twiss, I.M.3
  • 71
    • 79551589237 scopus 로고    scopus 로고
    • L-arginine supplementation and metabolism in asthma
    • Kenyon N, Last M, Bratt J, et al: L-arginine supplementation and metabolism in asthma. Pharmaceuticals 2011; 4: 187-201.
    • (2011) Pharmaceuticals , vol.4 , pp. 187-201
    • Kenyon, N.1    Last, M.2    Bratt, J.3
  • 72
    • 0035490032 scopus 로고    scopus 로고
    • Oral citrulline as arginine precursor may be beneficial in sickle cell disease: Early phase two results
    • Waugh WH, Daeschner III CW, Files BA, et al: Oral citrulline as arginine precursor may be beneficial in sickle cell disease: early phase two results. J Natl Med Assoc 2001; 93: 363-371.
    • (2001) J Natl Med Assoc , vol.93 , pp. 363-371
    • Waugh, W.H.1    Daeschner, C.W.2    Files, B.A.3
  • 73
    • 84949125826 scopus 로고    scopus 로고
    • Metabolic fate of oral glutamine supplementation within plasma and erythrocytes of patients with sickle cell disease: Preliminary pharmacokinetics results (abstract)
    • Morris C, Kuypers FA, Hagar R, et al: Metabolic fate of oral glutamine supplementation within plasma and erythrocytes of patients with sickle cell disease: preliminary pharmacokinetics results (abstract). Blood 2010; 116: 1636.
    • (2010) Blood , vol.116 , pp. 1636
    • Morris, C.1    Kuypers, F.A.2    Hagar, R.3
  • 74
    • 33845543076 scopus 로고    scopus 로고
    • The mouse trap: It still yields few answers in asthma
    • Wenzel S, Holgate ST: The mouse trap: it still yields few answers in asthma. Am J Respir Crit Care Med 2006; 174: 1173-1178.
    • (2006) Am J Respir Crit Care Med , vol.174 , pp. 1173-1178
    • Wenzel, S.1    Holgate, S.T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.