Beneficial effects of high dose of L-arginine on airway hyperresponsiveness and airway inflammation in a murine model of asthma

Journal of Allergy and Clinical Immunology

Volumn 125, Issue 3, 2010, Pages 626-635

  Mabalirajan, Ulaganathan ^a   Ahmad, Tanveer ^a   Leishangthem, Geeta Devi ^b   Joseph, Duraisamy Arul ^a   Dinda, Amit Kumar ^b   Agrawal, Anurag ^a   Ghosh, Balaram ^a  

^a CSIR INSTITUTE OF GENOMICS AND INTEGRATIVE BIOLOGY   (India)

^b ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Allergic airway inflammation; arginase; endothelial nitric oxide synthase; exhaled nitric oxide; L arginine

Indexed keywords

3 NITROTYROSINE; 8 HYDROXYDEOXYGUANOSINE; 8 ISOPROSTANE; ARGINASE 1; ARGININE; CYCLIC GMP; CYTOKINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE; OVALBUMIN; PEROXYNITRITE;

AIRWAY HYPERRESPONSIVENESS; AIRWAY INFLAMMATION; ALLERGIC ASTHMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRONCHUS MUCOSA; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; DRUG DOSE TITRATION; DRUG MECHANISM; DRUG MEGADOSE; EOSINOPHILIA; GOBLET CELL; LIPID PEROXIDATION; LOW DRUG DOSE; LUNG; LUNG FIBROSIS; LUNG LAVAGE; MALE; METAPLASIA; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY TRACT DISEASE; SENSITIZATION; TH2 CELL;

ANIMALS; ARGINASE; ARGININE; ASTHMA; BLOTTING, WESTERN; BRONCHIAL HYPERREACTIVITY; DISEASE MODELS, ANIMAL; EOSINOPHILIA; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MALE; MICE; MICE, INBRED BALB C; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; OXIDATIVE STRESS;

EID: 77649275723     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2009.10.065     Document Type: Article

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