Ribosomal protein s15 phosphorylation mediates LRRK2 neurodegeneration in parkinson's disease

Cell

Volumn 157, Issue 2, 2014, Pages 472-485

  Martin, Ian ^a,d   Kim, Jungwoo Wren ^a,d   Lee, Byoung Dae ^a,b   Kang, Ho Chul ^a,c   Xu, Jin Chong ^a   Jia, Hao ^a,d   Stankowski, Jeannette ^a,d   Kim, Min Sik ^a   Zhong, Jun ^a   Kumar, Manoj ^a   Andrabi, Shaida A ^a,d   Xiong, Yulan ^a   Dickson, Dennis W ^f   Wszolek, Zbigniew K ^g   Pandey, Akhilesh ^a,d,e   Dawson, Ted M ^a,d   Dawson, Valina L ^a,d  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Kyung Hee University   (South Korea)

^c Ajou University School of Medicine   (South Korea)

^d ADRIENNE HELIS MALVIN MEDICAL RESEARCH FOUNDATION   (United States)

^e Diana Helis Henry Medical Research Foundation   (United States)

^f MAYO GRADUATE SCHOOL   (United States)

^g MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; LEUCINE RICH REPEAT KINASE 2; MESSENGER RNA; RIBOSOME PROTEIN; RIBOSOME PROTEIN S15; THREONINE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CELL; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; DROSOPHILA; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LOCOMOTION; NERVE CELL; NERVE CELL NECROSIS; NERVE DEGENERATION; NEURITE; NEUROPATHOLOGY; NEUROTOXICITY; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; RNA TRANSLATION; TRANSGENIC DROSOPHILA;

AMINO ACID SEQUENCE; ANIMALS; DROSOPHILA MELANOGASTER; HUMANS; MOLECULAR SEQUENCE DATA; NEURONS; PARKINSON DISEASE; PROTEIN-SERINE-THREONINE KINASES; RIBOSOMAL PROTEINS;

EID: 84898622052     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2014.01.064     Document Type: Article

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