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Volumn 592, Issue 8, 2014, Pages 1887-1901

Vitamin C and E supplementation hampers cellular adaptation to endurance training in humans: A double-blind, randomised, controlled trial

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; CYTOCHROME C OXIDASE 4; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; OXIDOREDUCTASE; OXYGEN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PLACEBO; PROTEIN CDC42; UNCLASSIFIED DRUG; COX4I2 PROTEIN, HUMAN; CYTOCHROME C OXIDASE; PPARGC1A PROTEIN, HUMAN; TRANSCRIPTION FACTOR; VITAMIN;

EID: 84898546810     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2013.267419     Document Type: Article
Times cited : (238)

References (55)
  • 1
    • 0346995406 scopus 로고    scopus 로고
    • Vitamins in human arteriosclerosis with emphasis on vitamin C and vitamin E
    • Abudu N, Miller JJ, Attaelmannan M & Levinson SS (2004). Vitamins in human arteriosclerosis with emphasis on vitamin C and vitamin E. Clin Chim Acta 339, 11-25.
    • (2004) Clin Chim Acta , vol.339 , pp. 11-25
    • Abudu, N.1    Miller, J.J.2    Attaelmannan, M.3    Levinson, S.S.4
  • 2
    • 34547541720 scopus 로고    scopus 로고
    • Antioxidant diet supplementation enhances aerobic performance in amateur sportsmen
    • Aguilo A, Tauler P, Sureda A, Cases N, Tur J & Pons A (2007). Antioxidant diet supplementation enhances aerobic performance in amateur sportsmen. J Sports Sci 25, 1203-1210.
    • (2007) J Sports Sci , vol.25 , pp. 1203-1210
    • Aguilo, A.1    Tauler, P.2    Sureda, A.3    Cases, N.4    Tur, J.5    Pons, A.6
  • 3
    • 84865161025 scopus 로고    scopus 로고
    • Utility of multifrequency bioelectrical impedance compared with dual-energy x-ray absorptiometry for assessment of total and regional body composition varies between men and women
    • Anderson LJ, Erceg DN & Schroeder ET (2012). Utility of multifrequency bioelectrical impedance compared with dual-energy x-ray absorptiometry for assessment of total and regional body composition varies between men and women. Nutr Res 32, 479-485.
    • (2012) Nutr Res , vol.32 , pp. 479-485
    • Anderson, L.J.1    Erceg, D.N.2    Schroeder, E.T.3
  • 5
    • 69849096847 scopus 로고    scopus 로고
    • 2α concentrations as a biomarker of oxidative stress using triple-stage liquid chromatography/tandem mass spectrometry
    • 2α concentrations as a biomarker of oxidative stress using triple-stage liquid chromatography/tandem mass spectrometry. Rapid Commun Mass Spectrom 23, 2885-2890.
    • (2009) Rapid Commun Mass Spectrom , vol.23 , pp. 2885-2890
    • Bastani, N.E.1    Gundersen, T.E.2    Blomhoff, R.3
  • 7
    • 13244259144 scopus 로고    scopus 로고
    • Factors regulating isoprostane formation in vivo
    • Basu S & Helmersson J (2005). Factors regulating isoprostane formation in vivo. Antioxid Redox Signal 7, 221-235.
    • (2005) Antioxid Redox Signal , vol.7 , pp. 221-235
    • Basu, S.1    Helmersson, J.2
  • 8
    • 0026354769 scopus 로고
    • Critical evaluation of energy intake data using fundamental principles of energy physiology: 2. Evaluating the results of published surveys
    • Black AE, Goldberg GR, Jebb SA, Livingstone MB, Cole TJ & Prentice AM (1991). Critical evaluation of energy intake data using fundamental principles of energy physiology: 2. Evaluating the results of published surveys. Eur J Clin Nutr 45, 583-599.
    • (1991) Eur J Clin Nutr , vol.45 , pp. 583-599
    • Black, A.E.1    Goldberg, G.R.2    Jebb, S.A.3    Livingstone, M.B.4    Cole, T.J.5    Prentice, A.M.6
  • 9
    • 0026460826 scopus 로고
    • Vitamin E in human low-density lipoprotein. When and how this antioxidant becomes a pro-oxidant
    • Bowry VW, Ingold KU & Stocker R (1992). Vitamin E in human low-density lipoprotein. When and how this antioxidant becomes a pro-oxidant. Biochem J 288, 341-344.
    • (1992) Biochem J , vol.288 , pp. 341-344
    • Bowry, V.W.1    Ingold, K.U.2    Stocker, R.3
  • 10
    • 84867150348 scopus 로고    scopus 로고
    • Effect of vitamin C supplements on physical performance
    • Braakhuis AJ (2012). Effect of vitamin C supplements on physical performance. Curr Sports Med Rep 11, 180-184.
    • (2012) Curr Sports Med Rep , vol.11 , pp. 180-184
    • Braakhuis, A.J.1
  • 11
    • 84894025937 scopus 로고    scopus 로고
    • Effects of dietary antioxidants on training and performance in female runners
    • [in press; doi:10.1080/17461391.2013.785597].
    • Braakhuis AJ, Hopkins WG & Lowe TE (2014). Effects of dietary antioxidants on training and performance in female runners. Eur J Sport Sci [in press; doi:10.1080/17461391.2013.785597].
    • (2014) Eur J Sport Sci
    • Braakhuis, A.J.1    Hopkins, W.G.2    Lowe, T.E.3
  • 12
    • 0031976862 scopus 로고    scopus 로고
    • Human plasma and tissue α-tocopherol concentrations in response to supplementation with deuterated natural and synthetic vitamin E
    • Burton GW, Traber MG, Acuff RV, Walters DN, Kayden H, Hughes L & Ingold KU (1998). Human plasma and tissue α-tocopherol concentrations in response to supplementation with deuterated natural and synthetic vitamin E. Am J Clin Nutr 67, 669-684.
    • (1998) Am J Clin Nutr , vol.67 , pp. 669-684
    • Burton, G.W.1    Traber, M.G.2    Acuff, R.V.3    Walters, D.N.4    Kayden, H.5    Hughes, L.6    Ingold, K.U.7
  • 14
    • 84884565604 scopus 로고    scopus 로고
    • A randomized steady-state bioavailability study of synthetic versus natural (kiwifruit-derived) vitamin C
    • Carr AC, Bozonet SM, Pullar JM, Simcock JW & Vissers MC (2013). A randomized steady-state bioavailability study of synthetic versus natural (kiwifruit-derived) vitamin C. Nutrients 5, 3684-3695.
    • (2013) Nutrients , vol.5 , pp. 3684-3695
    • Carr, A.C.1    Bozonet, S.M.2    Pullar, J.M.3    Simcock, J.W.4    Vissers, M.C.5
  • 15
    • 34548371839 scopus 로고    scopus 로고
    • The molecular bases of training adaptation
    • Coffey VG & Hawley JA (2007). The molecular bases of training adaptation. Sports Med 37, 737-763.
    • (2007) Sports Med , vol.37 , pp. 737-763
    • Coffey, V.G.1    Hawley, J.A.2
  • 16
    • 84874111507 scopus 로고    scopus 로고
    • Training-induced mitochondrial adaptation: role of peroxisome proliferator-activated receptor γ coactivator-1α, nuclear factor-κB and β-blockade
    • Feng H, Kang C, Dickman JR, Koenig R, Awoyinka I, Zhang Y & Ji LL (2013). Training-induced mitochondrial adaptation: role of peroxisome proliferator-activated receptor γ coactivator-1α, nuclear factor-κB and β-blockade. Exp Physiol 98, 784-795.
    • (2013) Exp Physiol , vol.98 , pp. 784-795
    • Feng, H.1    Kang, C.2    Dickman, J.R.3    Koenig, R.4    Awoyinka, I.5    Zhang, Y.6    Ji, L.L.7
  • 17
    • 79959902659 scopus 로고    scopus 로고
    • American College of Sports Medicine position stand. Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: guidance for prescribing exercise
    • Garber CE, Blissmer B, Deschenes MR, Franklin BA, Lamonte MJ, Lee IM, Nieman DC & Swain DP (2011). American College of Sports Medicine position stand. Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: guidance for prescribing exercise. Med Sci Sports Exerc 43, 1334-1359.
    • (2011) Med Sci Sports Exerc , vol.43 , pp. 1334-1359
    • Garber, C.E.1    Blissmer, B.2    Deschenes, M.R.3    Franklin, B.A.4    Lamonte, M.J.5    Lee, I.M.6    Nieman, D.C.7    Swain, D.P.8
  • 18
    • 34547772278 scopus 로고    scopus 로고
    • High-intensity interval training: a time-efficient strategy for health promotion?
    • Gibala MJ (2007). High-intensity interval training: a time-efficient strategy for health promotion? Curr Sports Med Rep 6, 211-213.
    • (2007) Curr Sports Med Rep , vol.6 , pp. 211-213
    • Gibala, M.J.1
  • 20
    • 38149131289 scopus 로고    scopus 로고
    • Oral administration of vitamin C decreases muscle mitochondrial biogenesis and hampers training-induced adaptations in endurance performance
    • Gomez-Cabrera MC, Domenech E, Romagnoli M, Arduini A, Borras C, Pallardo FV, Sastre J & Vina J (2008). Oral administration of vitamin C decreases muscle mitochondrial biogenesis and hampers training-induced adaptations in endurance performance. Am J Clin Nutr 87, 142-149.
    • (2008) Am J Clin Nutr , vol.87 , pp. 142-149
    • Gomez-Cabrera, M.C.1    Domenech, E.2    Romagnoli, M.3    Arduini, A.4    Borras, C.5    Pallardo, F.V.6    Sastre, J.7    Vina, J.8
  • 22
    • 79251486187 scopus 로고    scopus 로고
    • Nutritional modulation of training-induced skeletal muscle adaptations
    • Hawley JA, Burke LM, Phillips SM & Spriet LL (2011). Nutritional modulation of training-induced skeletal muscle adaptations. J Appl Physiol 110, 834-845.
    • (2011) J Appl Physiol , vol.110 , pp. 834-845
    • Hawley, J.A.1    Burke, L.M.2    Phillips, S.M.3    Spriet, L.L.4
  • 23
    • 0026803042 scopus 로고
    • Effects of physical training on the metabolism of skeletal muscle
    • Henriksson J (1992). Effects of physical training on the metabolism of skeletal muscle. Diabetes Care 15, 1701-1711.
    • (1992) Diabetes Care , vol.15 , pp. 1701-1711
    • Henriksson, J.1
  • 24
    • 27944479854 scopus 로고    scopus 로고
    • Rho GTPases: biochemistry and biology
    • Jaffe AB & Hall A (2005). Rho GTPases: biochemistry and biology. Annu Rev Cell Dev Biol 21, 247-269.
    • (2005) Annu Rev Cell Dev Biol , vol.21 , pp. 247-269
    • Jaffe, A.B.1    Hall, A.2
  • 25
    • 70350020773 scopus 로고    scopus 로고
    • Exercise activation of muscle peroxisome proliferator-activated receptor-γ coactivator-1α signalling is redox sensitive
    • Kang C, O'Moore KM, Dickman JR & Ji LL (2009). Exercise activation of muscle peroxisome proliferator-activated receptor-γ coactivator-1α signalling is redox sensitive. Free Radic Biol Med 47, 1394-1400.
    • (2009) Free Radic Biol Med , vol.47 , pp. 1394-1400
    • Kang, C.1    O'Moore, K.M.2    Dickman, J.R.3    Ji, L.L.4
  • 26
    • 24044482924 scopus 로고    scopus 로고
    • High-throughput analysis of vitamin C in human plasma with the use of HPLC with monolithic column and UV-detection
    • Karlsen A, Blomhoff R & Gundersen TE (2005). High-throughput analysis of vitamin C in human plasma with the use of HPLC with monolithic column and UV-detection. J Chromatogr B Analyt Technol Biomed Life Sci 824, 132-138.
    • (2005) J Chromatogr B Analyt Technol Biomed Life Sci , vol.824 , pp. 132-138
    • Karlsen, A.1    Blomhoff, R.2    Gundersen, T.E.3
  • 27
    • 84871910695 scopus 로고    scopus 로고
    • Dietary supplement use pattern of US adult population in the 2007-2008 National Health and Nutrition Examination Survey (NHANES)
    • Kennedy ET, Luo H & Houser RF (2013). Dietary supplement use pattern of US adult population in the 2007-2008 National Health and Nutrition Examination Survey (NHANES). Ecol Food Nutr 52, 76-84.
    • (2013) Ecol Food Nutr , vol.52 , pp. 76-84
    • Kennedy, E.T.1    Luo, H.2    Houser, R.F.3
  • 28
    • 77954335451 scopus 로고    scopus 로고
    • Regulation of skeletal muscle mitochondrial function: genes to proteins
    • Lanza IR & Sreekumaran NK (2010). Regulation of skeletal muscle mitochondrial function: genes to proteins. Acta Physiol (Oxf) 199, 529-547.
    • (2010) Acta Physiol (Oxf) , vol.199 , pp. 529-547
    • Lanza, I.R.1    Sreekumaran, N.K.2
  • 30
    • 0024029143 scopus 로고
    • The multistage 20 metre shuttle run test for aerobic fitness
    • Leger LA, Mercier D, Gadoury C & Lambert J (1988). The multistage 20 metre shuttle run test for aerobic fitness. J Sports Sci 6, 93-101.
    • (1988) J Sports Sci , vol.6 , pp. 93-101
    • Leger, L.A.1    Mercier, D.2    Gadoury, C.3    Lambert, J.4
  • 31
    • 68849112046 scopus 로고    scopus 로고
    • Cdc42GAP, reactive oxygen species, and the vimentin network
    • Li QF, Spinelli AM & Tang DD (2009). Cdc42GAP, reactive oxygen species, and the vimentin network. Am J Physiol Cell Physiol 297, C299-C309.
    • (2009) Am J Physiol Cell Physiol , vol.297
    • Li, Q.F.1    Spinelli, A.M.2    Tang, D.D.3
  • 32
    • 33744500780 scopus 로고    scopus 로고
    • Response and function of skeletal muscle heat shock protein 70
    • Liu Y, Gampert L, Nething K & Steinacker JM (2006). Response and function of skeletal muscle heat shock protein 70. Front Biosci 11, 2802-2827.
    • (2006) Front Biosci , vol.11 , pp. 2802-2827
    • Liu, Y.1    Gampert, L.2    Nething, K.3    Steinacker, J.M.4
  • 34
    • 84890068248 scopus 로고    scopus 로고
    • Free radicals and sprint exercise in humans
    • Morales-Alamo D & Calbet JA (2014). Free radicals and sprint exercise in humans. Free Radic Res 48, 30-42.
    • (2014) Free Radic Res , vol.48 , pp. 30-42
    • Morales-Alamo, D.1    Calbet, J.A.2
  • 35
    • 66349132499 scopus 로고    scopus 로고
    • Reduced carbohydrate availability does not modulate training-induced heat shock protein adaptations but does upregulate oxidative enzyme activity in human skeletal muscle
    • Morton JP, Croft L, Bartlett JD, MacLaren DP, Reilly T, Evans L, McArdle A & Drust B (2009a). Reduced carbohydrate availability does not modulate training-induced heat shock protein adaptations but does upregulate oxidative enzyme activity in human skeletal muscle. J Appl Physiol 106, 1513-1521.
    • (2009) J Appl Physiol , vol.106 , pp. 1513-1521
    • Morton, J.P.1    Croft, L.2    Bartlett, J.D.3    MacLaren, D.P.4    Reilly, T.5    Evans, L.6    McArdle, A.7    Drust, B.8
  • 36
    • 67651120134 scopus 로고    scopus 로고
    • The exercise-induced stress response of skeletal muscle, with specific emphasis on humans
    • Morton JP, Kayani AC, McArdle A & Drust B (2009b). The exercise-induced stress response of skeletal muscle, with specific emphasis on humans. Sports Med 39, 643-662.
    • (2009) Sports Med , vol.39 , pp. 643-662
    • Morton, J.P.1    Kayani, A.C.2    McArdle, A.3    Drust, B.4
  • 38
    • 84866157093 scopus 로고    scopus 로고
    • Does vitamin C and E supplementation impair the favorable adaptations of regular exercise?
    • Nikolaidis MG, Kerksick CM, Lamprecht M & McAnulty SR (2012). Does vitamin C and E supplementation impair the favorable adaptations of regular exercise? Oxid Med Cell Longev 2012, 707941.
    • (2012) Oxid Med Cell Longev , vol.2012 , pp. 707941
    • Nikolaidis, M.G.1    Kerksick, C.M.2    Lamprecht, M.3    McAnulty, S.R.4
  • 41
    • 80755171414 scopus 로고    scopus 로고
    • Antioxidant supplementation during exercise training: beneficial or detrimental?
    • Peternelj TT & Coombes JS (2011). Antioxidant supplementation during exercise training: beneficial or detrimental? Sports Med 41, 1043-1069.
    • (2011) Sports Med , vol.41 , pp. 1043-1069
    • Peternelj, T.T.1    Coombes, J.S.2
  • 43
    • 77952548782 scopus 로고    scopus 로고
    • How increased oxidative stress promotes longevity and metabolic health: the concept of mitochondrial hormesis (mitohormesis)
    • Ristow M & Zarse K (2010). How increased oxidative stress promotes longevity and metabolic health: the concept of mitochondrial hormesis (mitohormesis). Exp Gerontol 45, 410-418.
    • (2010) Exp Gerontol , vol.45 , pp. 410-418
    • Ristow, M.1    Zarse, K.2
  • 45
    • 0037069363 scopus 로고    scopus 로고
    • Effect of diet and exercise intervention on blood pressure, insulin, oxidative stress, and nitric oxide availability
    • Roberts CK, Vaziri ND & Barnard RJ (2002). Effect of diet and exercise intervention on blood pressure, insulin, oxidative stress, and nitric oxide availability. Circulation 106, 2530-2532.
    • (2002) Circulation , vol.106 , pp. 2530-2532
    • Roberts, C.K.1    Vaziri, N.D.2    Barnard, R.J.3
  • 46
    • 79952947280 scopus 로고    scopus 로고
    • Vitamin C consumption does not impair training-induced improvements in exercise performance
    • Roberts LA, Beattie K, Close GL & Morton JP (2011). Vitamin C consumption does not impair training-induced improvements in exercise performance. Int J Sports Physiol Perform 6, 58-69.
    • (2011) Int J Sports Physiol Perform , vol.6 , pp. 58-69
    • Roberts, L.A.1    Beattie, K.2    Close, G.L.3    Morton, J.P.4
  • 47
    • 84864186432 scopus 로고    scopus 로고
    • PGC-1α is dispensable for exercise-induced mitochondrial biogenesis in skeletal muscle
    • Rowe GC, El-Khoury R, Patten IS, Rustin P & Arany Z (2012). PGC-1α is dispensable for exercise-induced mitochondrial biogenesis in skeletal muscle. PLoS One 7, e41817.
    • (2012) PLoS One , vol.7
    • Rowe, G.C.1    El-Khoury, R.2    Patten, I.S.3    Rustin, P.4    Arany, Z.5
  • 48
    • 0014127568 scopus 로고
    • Maximal oxygen uptake in athletes
    • Saltin B & Astrand PO (1967). Maximal oxygen uptake in athletes. J Appl Physiol 23, 353-358.
    • (1967) J Appl Physiol , vol.23 , pp. 353-358
    • Saltin, B.1    Astrand, P.O.2
  • 51
    • 0028077110 scopus 로고
    • Human plasma vitamin E kinetics demonstrate rapid recycling of plasma RRR-α-tocopherol
    • Traber MG, Ramakrishnan R & Kayden HJ (1994). Human plasma vitamin E kinetics demonstrate rapid recycling of plasma RRR-α-tocopherol. Proc Natl Acad Sci U S A 91, 10005-10008.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 10005-10008
    • Traber, M.G.1    Ramakrishnan, R.2    Kayden, H.J.3
  • 52
    • 84857682615 scopus 로고    scopus 로고
    • Antioxidant-induced stress
    • Villanueva C & Kross RD (2012). Antioxidant-induced stress. Int J Mol Sci 13, 2091-2109.
    • (2012) Int J Mol Sci , vol.13 , pp. 2091-2109
    • Villanueva, C.1    Kross, R.D.2


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