메뉴 건너뛰기




Volumn 38, Issue , 2014, Pages 202-210

Postoperative cognitive dysfunction: Involvement of neuroinflammation and neuronal functioning

Author keywords

Brain derived neurotrophic factor; Exploratory behavior; Learning and memory; Neurogenesis; Neuroinflammation; Postoperative cognitive dysfunction; Surgery

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; INTERLEUKIN 6; DOUBLECORTIN; INTERLEUKIN 1BETA; INTERLEUKIN DERIVATIVE;

EID: 84898540090     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2014.02.002     Document Type: Article
Times cited : (247)

References (65)
  • 1
    • 54749091291 scopus 로고    scopus 로고
    • Proteolysis of proBDNF is a key regulator in the formation of memory
    • Barnes P., Thomas K.L. Proteolysis of proBDNF is a key regulator in the formation of memory. PLoS One 2008, 3:e3248.
    • (2008) PLoS One , vol.3
    • Barnes, P.1    Thomas, K.L.2
  • 2
    • 4444338123 scopus 로고    scopus 로고
    • BDNF mRNA expression in rat hippocampus following contextual learning is blocked by intrahippocampal IL-1beta administration
    • Barrientos R.M., Sprunger D.B., Campeau S., Watkins L.R., Rudy J.W., Maier S.F. BDNF mRNA expression in rat hippocampus following contextual learning is blocked by intrahippocampal IL-1beta administration. J. Neuroimmunol. 2004, 155:119-126.
    • (2004) J. Neuroimmunol. , vol.155 , pp. 119-126
    • Barrientos, R.M.1    Sprunger, D.B.2    Campeau, S.3    Watkins, L.R.4    Rudy, J.W.5    Maier, S.F.6
  • 4
    • 84867604328 scopus 로고    scopus 로고
    • Intracisternal interleukin-1 receptor antagonist prevents postoperative cognitive decline and neuroinflammatory response in aged rats
    • Barrientos R.M., Hein A.M., Frank M.G., Watkins L.R., Maier S.F. Intracisternal interleukin-1 receptor antagonist prevents postoperative cognitive decline and neuroinflammatory response in aged rats. J. Neurosci. 2012, 32:14641-14648.
    • (2012) J. Neurosci. , vol.32 , pp. 14641-14648
    • Barrientos, R.M.1    Hein, A.M.2    Frank, M.G.3    Watkins, L.R.4    Maier, S.F.5
  • 6
    • 78751518199 scopus 로고    scopus 로고
    • Doublecortin-positive cells in the adult primate cerebral cortex and possible role in brain plasticity and development
    • Bloch J., Kaeser M., Sadeghi Y., Rouiller E.M., Redmond D.E., Brunet J.-F. Doublecortin-positive cells in the adult primate cerebral cortex and possible role in brain plasticity and development. J. Comp. Neurol. 2011, 519:775-789.
    • (2011) J. Comp. Neurol. , vol.519 , pp. 775-789
    • Bloch, J.1    Kaeser, M.2    Sadeghi, Y.3    Rouiller, E.M.4    Redmond, D.E.5    Brunet, J.-F.6
  • 7
    • 79953662385 scopus 로고    scopus 로고
    • Immune system to brain signaling: neuropsychopharmacological implications
    • Capuron L., Miller A.H. Immune system to brain signaling: neuropsychopharmacological implications. Pharmacol. Ther. 2011, 130:226-238.
    • (2011) Pharmacol. Ther. , vol.130 , pp. 226-238
    • Capuron, L.1    Miller, A.H.2
  • 8
    • 84864804010 scopus 로고    scopus 로고
    • Age-dependent decline of motor neocortex but not hippocampal performance in heterozygous BDNF mice correlates with a decrease of cortical PSD-95 but an increase of hippocampal TrkB levels
    • Carretón O., Giralt A., Torres-Peraza J.F., Brito V., Lucas J.J., Ginés S., Canals J.M., Alberch J. Age-dependent decline of motor neocortex but not hippocampal performance in heterozygous BDNF mice correlates with a decrease of cortical PSD-95 but an increase of hippocampal TrkB levels. Exp. Neurol. 2012, 237:335-345.
    • (2012) Exp. Neurol. , vol.237 , pp. 335-345
    • Carretón, O.1    Giralt, A.2    Torres-Peraza, J.F.3    Brito, V.4    Lucas, J.J.5    Ginés, S.6    Canals, J.M.7    Alberch, J.8
  • 9
    • 84879090188 scopus 로고    scopus 로고
    • Hydrogen sulfide attenuates surgical trauma-induced inflammatory response and cognitive deficits in mice
    • Chu Q.-J., He L., Zhang W., Liu C.-L., Ai Y.-Q., Zhang Q. Hydrogen sulfide attenuates surgical trauma-induced inflammatory response and cognitive deficits in mice. J. Surg. Res. 2013, 183:330-336.
    • (2013) J. Surg. Res. , vol.183 , pp. 330-336
    • Chu, Q.-J.1    He, L.2    Zhang, W.3    Liu, C.-L.4    Ai, Y.-Q.5    Zhang, Q.6
  • 11
    • 79952772473 scopus 로고    scopus 로고
    • Aging and a peripheral immune challenge interact to reduce mature brain-derived neurotrophic factor and activation of TrkB, PLCgamma1, and ERK in hippocampal synaptoneurosomes
    • Cortese G.P., Barrientos R.M., Maier S.F., Patterson S.L. Aging and a peripheral immune challenge interact to reduce mature brain-derived neurotrophic factor and activation of TrkB, PLCgamma1, and ERK in hippocampal synaptoneurosomes. J. Neurosci. 2011, 31:4274-4279.
    • (2011) J. Neurosci. , vol.31 , pp. 4274-4279
    • Cortese, G.P.1    Barrientos, R.M.2    Maier, S.F.3    Patterson, S.L.4
  • 12
    • 0034888287 scopus 로고    scopus 로고
    • Applications of the Morris water maze in the study of learning and memory
    • D'Hooge R., De Deyn P.P. Applications of the Morris water maze in the study of learning and memory. Brain Res. Brain Res. Rev. 2001, 36:60-90.
    • (2001) Brain Res. Brain Res. Rev. , vol.36 , pp. 60-90
    • D'Hooge, R.1    De Deyn, P.P.2
  • 13
    • 0035038172 scopus 로고    scopus 로고
    • Cytokine-induced sickness behavior: mechanisms and implications
    • Dantzer R. Cytokine-induced sickness behavior: mechanisms and implications. Ann. N. Y. Acad. Sci. 2001, 933:222-234.
    • (2001) Ann. N. Y. Acad. Sci. , vol.933 , pp. 222-234
    • Dantzer, R.1
  • 14
    • 37249094173 scopus 로고    scopus 로고
    • From inflammation to sickness and depression: when the immune system subjugates the brain
    • Dantzer R., O'Connor J.C., Freund G.G., Johnson R.W., Kelley K.W. From inflammation to sickness and depression: when the immune system subjugates the brain. Nat. Rev. 2008, 9:46-56.
    • (2008) Nat. Rev. , vol.9 , pp. 46-56
    • Dantzer, R.1    O'Connor, J.C.2    Freund, G.G.3    Johnson, R.W.4    Kelley, K.W.5
  • 15
    • 84874629777 scopus 로고    scopus 로고
    • Depletion of bone marrow-derived macrophages perturbs the innate immune response to surgery and reduces postoperative memory dysfunction
    • Degos V., Vacas S., Han Z., van Rooijen N., Gressens P., Su H., Young W.L., Maze M. Depletion of bone marrow-derived macrophages perturbs the innate immune response to surgery and reduces postoperative memory dysfunction. Anesthesiology 2013, 118:527-536.
    • (2013) Anesthesiology , vol.118 , pp. 527-536
    • Degos, V.1    Vacas, S.2    Han, Z.3    van Rooijen, N.4    Gressens, P.5    Su, H.6    Young, W.L.7    Maze, M.8
  • 16
    • 34247574175 scopus 로고    scopus 로고
    • The pharmacology, neuroanatomy and neurogenetics of one-trial object recognition in rodents
    • Dere E., Huston J.P., De Souza Silva M.A. The pharmacology, neuroanatomy and neurogenetics of one-trial object recognition in rodents. Neurosci. Biobehav. Rev. 2007, 31:673-704.
    • (2007) Neurosci. Biobehav. Rev. , vol.31 , pp. 673-704
    • Dere, E.1    Huston, J.P.2    De Souza Silva, M.A.3
  • 17
    • 54249124166 scopus 로고    scopus 로고
    • Aging, microglial cell priming, and the discordant central inflammatory response to signals from the peripheral immune system
    • Dilger R.N., Johnson R.W. Aging, microglial cell priming, and the discordant central inflammatory response to signals from the peripheral immune system. J. Leukoc. Biol. 2008, 84:932-939.
    • (2008) J. Leukoc. Biol. , vol.84 , pp. 932-939
    • Dilger, R.N.1    Johnson, R.W.2
  • 18
    • 79958108784 scopus 로고    scopus 로고
    • Systemic inflammation enhances surgery-induced cognitive dysfunction in mice
    • Fidalgo A.R., Cibelli M., White J.P., Nagy I., Maze M., Ma D. Systemic inflammation enhances surgery-induced cognitive dysfunction in mice. Neurosci. Lett. 2011, 498:63-66.
    • (2011) Neurosci. Lett. , vol.498 , pp. 63-66
    • Fidalgo, A.R.1    Cibelli, M.2    White, J.P.3    Nagy, I.4    Maze, M.5    Ma, D.6
  • 19
    • 80051589177 scopus 로고    scopus 로고
    • Peripheral orthopaedic surgery down-regulates hippocampal brain-derived neurotrophic factor and impairs remote memory in mouse
    • Fidalgo A.R., Cibelli M., White J.P., Nagy I., Noormohamed F., Benzonana L., Maze M., Ma D. Peripheral orthopaedic surgery down-regulates hippocampal brain-derived neurotrophic factor and impairs remote memory in mouse. Neuroscience 2011, 190:194-199.
    • (2011) Neuroscience , vol.190 , pp. 194-199
    • Fidalgo, A.R.1    Cibelli, M.2    White, J.P.3    Nagy, I.4    Noormohamed, F.5    Benzonana, L.6    Maze, M.7    Ma, D.8
  • 20
    • 84872198466 scopus 로고    scopus 로고
    • Poly I:C-induced activation of the immune response is accompanied by depression and anxiety-like behaviours, kynurenine pathway activation and reduced BDNF expression
    • Gibney S.M., McGuinness B., Prendergast C., Harkin A., Connor T.J. Poly I:C-induced activation of the immune response is accompanied by depression and anxiety-like behaviours, kynurenine pathway activation and reduced BDNF expression. Brain Behav. Immun. 2013, 28:170-181.
    • (2013) Brain Behav. Immun. , vol.28 , pp. 170-181
    • Gibney, S.M.1    McGuinness, B.2    Prendergast, C.3    Harkin, A.4    Connor, T.J.5
  • 24
    • 29144444066 scopus 로고    scopus 로고
    • Peripheral immune activation by lipopolysaccharide decreases neurotrophins in the cortex and hippocampus in rats
    • Guan Z., Fang J. Peripheral immune activation by lipopolysaccharide decreases neurotrophins in the cortex and hippocampus in rats. Brain Behav. Immun. 2006, 20:64-71.
    • (2006) Brain Behav. Immun. , vol.20 , pp. 64-71
    • Guan, Z.1    Fang, J.2
  • 25
    • 84865640010 scopus 로고    scopus 로고
    • Thinking through postoperative cognitive dysfunction: how to bridge the gap between clinical and pre-clinical perspectives
    • Hovens I.B., Schoemaker R.G., van der Zee E.A., Heineman E., Izaks G.J., van Leeuwen B.L. Thinking through postoperative cognitive dysfunction: how to bridge the gap between clinical and pre-clinical perspectives. Brain Behav. Immun. 2012, 26:1169-1179.
    • (2012) Brain Behav. Immun. , vol.26 , pp. 1169-1179
    • Hovens, I.B.1    Schoemaker, R.G.2    van der Zee, E.A.3    Heineman, E.4    Izaks, G.J.5    van Leeuwen, B.L.6
  • 28
    • 79952245068 scopus 로고    scopus 로고
    • Elevated postoperative inflammatory biomarkers are associated with short- and medium-term cognitive dysfunction after coronary artery surgery
    • Hudetz J.A., Gandhi S.D., Iqbal Z., Patterson K.M., Pagel P.S. Elevated postoperative inflammatory biomarkers are associated with short- and medium-term cognitive dysfunction after coronary artery surgery. J. Anesth. 2011, 25:1-9.
    • (2011) J. Anesth. , vol.25 , pp. 1-9
    • Hudetz, J.A.1    Gandhi, S.D.2    Iqbal, Z.3    Patterson, K.M.4    Pagel, P.S.5
  • 29
    • 79960036111 scopus 로고    scopus 로고
    • Postoperative cognitive dysfunction after noncardiac surgery: effects of metabolic syndrome
    • Hudetz J.A., Patterson K.M., Amole O., Riley A.V., Pagel P.S. Postoperative cognitive dysfunction after noncardiac surgery: effects of metabolic syndrome. J. Anesth. 2011, 25:337-344.
    • (2011) J. Anesth. , vol.25 , pp. 337-344
    • Hudetz, J.A.1    Patterson, K.M.2    Amole, O.3    Riley, A.V.4    Pagel, P.S.5
  • 30
    • 84881557475 scopus 로고    scopus 로고
    • Changes in plasma and cerebrospinal fluid biomarkers in aged patients with early postoperative cognitive dysfunction following total hip-replacement surgery
    • Ji M.-H., Yuan H.-M., Zhang G.-F., Li X.-M., Dong L., Li W.-Y., Zhou Z.-Q., Yang J.-J. Changes in plasma and cerebrospinal fluid biomarkers in aged patients with early postoperative cognitive dysfunction following total hip-replacement surgery. J. Anesth. 2013, 27:236-242.
    • (2013) J. Anesth. , vol.27 , pp. 236-242
    • Ji, M.-H.1    Yuan, H.-M.2    Zhang, G.-F.3    Li, X.-M.4    Dong, L.5    Li, W.-Y.6    Zhou, Z.-Q.7    Yang, J.-J.8
  • 32
    • 77955262711 scopus 로고    scopus 로고
    • New insights into the pathophysiology of postoperative cognitive dysfunction
    • Krenk L., Rasmussen L.S., Kehlet H. New insights into the pathophysiology of postoperative cognitive dysfunction. Acta Anaesthesiol. Scand. 2010, 54:951-956.
    • (2010) Acta Anaesthesiol. Scand. , vol.54 , pp. 951-956
    • Krenk, L.1    Rasmussen, L.S.2    Kehlet, H.3
  • 33
    • 0030222037 scopus 로고    scopus 로고
    • Microglia: a sensor for pathological events in the CNS
    • Kreutzberg G.W. Microglia: a sensor for pathological events in the CNS. Trends Neurosci. 1996, 19:312-318.
    • (1996) Trends Neurosci. , vol.19 , pp. 312-318
    • Kreutzberg, G.W.1
  • 34
    • 2442507983 scopus 로고    scopus 로고
    • Independent cellular processes for hippocampal memory consolidation and reconsolidation
    • Lee J.L.C., Everitt B.J., Thomas K.L. Independent cellular processes for hippocampal memory consolidation and reconsolidation. Science 2004, 304:839-843.
    • (2004) Science , vol.304 , pp. 839-843
    • Lee, J.L.C.1    Everitt, B.J.2    Thomas, K.L.3
  • 36
    • 84876190130 scopus 로고    scopus 로고
    • Ulinastatin alleviates neuroinflammation but fails to improve cognitive function in aged rats following partial hepatectomy
    • Li M., Yong-Zhe L., Ya-Qun M., Sheng-Suo Z., Li-Tao Z., Ning-Ling P. Ulinastatin alleviates neuroinflammation but fails to improve cognitive function in aged rats following partial hepatectomy. Neurochem. Res. 2013, 38:1070-1077.
    • (2013) Neurochem. Res. , vol.38 , pp. 1070-1077
    • Li, M.1    Yong-Zhe, L.2    Ya-Qun, M.3    Sheng-Suo, Z.4    Li-Tao, Z.5    Ning-Ling, P.6
  • 37
    • 39849083186 scopus 로고    scopus 로고
    • BDNF: a key regulator for protein synthesis-dependent LTP and long-term memory?
    • Lu Y., Christian K., Lu B. BDNF: a key regulator for protein synthesis-dependent LTP and long-term memory?. Neurobiol. Learn. Mem. 2008, 89:312-323.
    • (2008) Neurobiol. Learn. Mem. , vol.89 , pp. 312-323
    • Lu, Y.1    Christian, K.2    Lu, B.3
  • 39
    • 0036833427 scopus 로고    scopus 로고
    • Early postoperative compensatory anti-inflammatory response syndrome is associated with septic complications after major surgical trauma in patients with cancer
    • Mokart D., Capo C., Blache J.L., Delpero J.R., Houvenaeghel G., Martin C., Mege J.L. Early postoperative compensatory anti-inflammatory response syndrome is associated with septic complications after major surgical trauma in patients with cancer. Br. J. Surg. 2002, 89:1450-1456.
    • (2002) Br. J. Surg. , vol.89 , pp. 1450-1456
    • Mokart, D.1    Capo, C.2    Blache, J.L.3    Delpero, J.R.4    Houvenaeghel, G.5    Martin, C.6    Mege, J.L.7
  • 43
    • 34247525052 scopus 로고    scopus 로고
    • Postoperative cognitive dysfunction after noncardiac surgery: a systematic review
    • Newman S., Stygall J., Hirani S., Shaefi S., Maze M. Postoperative cognitive dysfunction after noncardiac surgery: a systematic review. Anesthesiology 2007, 106:572-590.
    • (2007) Anesthesiology , vol.106 , pp. 572-590
    • Newman, S.1    Stygall, J.2    Hirani, S.3    Shaefi, S.4    Maze, M.5
  • 44
    • 84880182899 scopus 로고    scopus 로고
    • Transient domoic acid excitotoxicity increases BDNF expression and activates both MEK- and PKA-dependent neurogenesis in organotypic hippocampal slices
    • Pérez-Gómez A., Tasker R.A. Transient domoic acid excitotoxicity increases BDNF expression and activates both MEK- and PKA-dependent neurogenesis in organotypic hippocampal slices. BMC Neurosci. 2013, 14:72.
    • (2013) BMC Neurosci. , vol.14 , pp. 72
    • Pérez-Gómez, A.1    Tasker, R.A.2
  • 45
    • 77955442296 scopus 로고    scopus 로고
    • Quantification of ischemia-reperfusion injury to the small intestine using a macroscopic score
    • Petrat F., Swoboda S., de Groot H., Schmitz K.J. Quantification of ischemia-reperfusion injury to the small intestine using a macroscopic score. J. Invest. Surg. 2010, 23:208-217.
    • (2010) J. Invest. Surg. , vol.23 , pp. 208-217
    • Petrat, F.1    Swoboda, S.2    de Groot, H.3    Schmitz, K.J.4
  • 47
    • 33744549746 scopus 로고    scopus 로고
    • Postoperative cognitive dysfunction: incidence and prevention
    • Rasmussen L.S. Postoperative cognitive dysfunction: incidence and prevention. Best Pract. Res. Anaesthesiol. 2006, 20:315-330.
    • (2006) Best Pract. Res. Anaesthesiol. , vol.20 , pp. 315-330
    • Rasmussen, L.S.1
  • 48
    • 49649086873 scopus 로고    scopus 로고
    • Neuroinflammation and cognitive function in aged mice following minor surgery
    • Rosczyk H.A., Sparkman N.L., Johnson R.W. Neuroinflammation and cognitive function in aged mice following minor surgery. Exp. Gerontol. 2008, 43:840-846.
    • (2008) Exp. Gerontol. , vol.43 , pp. 840-846
    • Rosczyk, H.A.1    Sparkman, N.L.2    Johnson, R.W.3
  • 49
    • 0028024339 scopus 로고
    • Behavioral changes following chronic myocardial infarction in rats
    • Schoemaker R.G., Smits J.F. Behavioral changes following chronic myocardial infarction in rats. Physiol. Behav. 1994, 56:585-589.
    • (1994) Physiol. Behav. , vol.56 , pp. 585-589
    • Schoemaker, R.G.1    Smits, J.F.2
  • 51
    • 50849150363 scopus 로고
    • A method for frequent sampling of blood and continuous infusion of fluids in the rat without disturbing the animal
    • Steffens A.B. A method for frequent sampling of blood and continuous infusion of fluids in the rat without disturbing the animal. Physiol. Behav. 1969, 4:833-836.
    • (1969) Physiol. Behav. , vol.4 , pp. 833-836
    • Steffens, A.B.1
  • 53
    • 33644910893 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced microglial activation induces learning and memory deficits without neuronal cell death in rats
    • Tanaka S., Ide M., Shibutani T., Ohtaki H., Numazawa S., Shioda S., Yoshida T. Lipopolysaccharide-induced microglial activation induces learning and memory deficits without neuronal cell death in rats. J. Neurosci. Res. 2006, 83:557-566.
    • (2006) J. Neurosci. Res. , vol.83 , pp. 557-566
    • Tanaka, S.1    Ide, M.2    Shibutani, T.3    Ohtaki, H.4    Numazawa, S.5    Shioda, S.6    Yoshida, T.7
  • 56
    • 78650580820 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha triggers a cytokine cascade yielding postoperative cognitive decline
    • Terrando N., Monaco C., Ma D., Foxwell B.M., Feldmann M., Maze M. Tumor necrosis factor-alpha triggers a cytokine cascade yielding postoperative cognitive decline. Proc. Natl. Acad. Sci. USA 2010, 107:20518-20522.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 20518-20522
    • Terrando, N.1    Monaco, C.2    Ma, D.3    Foxwell, B.M.4    Feldmann, M.5    Maze, M.6
  • 58
    • 84870524516 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor-dependent synaptic plasticity is suppressed by interleukin-1B via p38 mitogen-activated protein kinase
    • Tong L., Prieto G.A., Kramár E.A., Smith E.D., Cribbs D.H., Lynch G., Cotman C.W. Brain-derived neurotrophic factor-dependent synaptic plasticity is suppressed by interleukin-1B via p38 mitogen-activated protein kinase. J. Neurosci. 2012, 32:17714-17724.
    • (2012) J. Neurosci. , vol.32 , pp. 17714-17724
    • Tong, L.1    Prieto, G.A.2    Kramár, E.A.3    Smith, E.D.4    Cribbs, D.H.5    Lynch, G.6    Cotman, C.W.7
  • 59
    • 34249689618 scopus 로고    scopus 로고
    • Exercise improves memory acquisition and retrieval in the Y-maze task: relationship with hippocampal neurogenesis
    • Van der Borght K., Havekes R., Bos T., Eggen B.J.L., Van der Zee E.A. Exercise improves memory acquisition and retrieval in the Y-maze task: relationship with hippocampal neurogenesis. Behav. Neurosci. 2007, 121:324-334.
    • (2007) Behav. Neurosci. , vol.121 , pp. 324-334
    • Van der Borght, K.1    Havekes, R.2    Bos, T.3    Eggen, B.J.L.4    Van der Zee, E.A.5
  • 60
    • 80455174272 scopus 로고    scopus 로고
    • Xenon pretreatment may prevent early memory decline after isoflurane anesthesia and surgery in mice
    • Vizcaychipi M.P., Lloyd D.G., Wan Y., Palazzo M.G., Maze M., Ma D. Xenon pretreatment may prevent early memory decline after isoflurane anesthesia and surgery in mice. PLoS One 2011, 6:e26394.
    • (2011) PLoS One , vol.6
    • Vizcaychipi, M.P.1    Lloyd, D.G.2    Wan, Y.3    Palazzo, M.G.4    Maze, M.5    Ma, D.6
  • 61
    • 34247497682 scopus 로고    scopus 로고
    • Postoperative impairment of cognitive function in rats: a possible role for cytokine-mediated inflammation in the hippocampus
    • Wan Y., Xu J., Ma D., Zeng Y., Cibelli M., Maze M. Postoperative impairment of cognitive function in rats: a possible role for cytokine-mediated inflammation in the hippocampus. Anesthesiology 2007, 106:436-443.
    • (2007) Anesthesiology , vol.106 , pp. 436-443
    • Wan, Y.1    Xu, J.2    Ma, D.3    Zeng, Y.4    Cibelli, M.5    Maze, M.6
  • 62
    • 78049446331 scopus 로고    scopus 로고
    • Cognitive decline following major surgery is associated with gliosis, beta-amyloid accumulation, and tau phosphorylation in old mice
    • Wan Y., Xu J., Meng F., Bao Y., Ge Y., Lobo N., Vizcaychipi M.P., Zhang D., Gentleman S.M., Maze M., Ma D. Cognitive decline following major surgery is associated with gliosis, beta-amyloid accumulation, and tau phosphorylation in old mice. Crit. Care Med. 2010, 38:2190-2198.
    • (2010) Crit. Care Med. , vol.38 , pp. 2190-2198
    • Wan, Y.1    Xu, J.2    Meng, F.3    Bao, Y.4    Ge, Y.5    Lobo, N.6    Vizcaychipi, M.P.7    Zhang, D.8    Gentleman, S.M.9    Maze, M.10    Ma, D.11
  • 63
    • 54049130105 scopus 로고    scopus 로고
    • The compensatory anti-inflammatory response syndrome (CARS) in critically ill patients
    • viii
    • Ward N.S., Casserly B., Ayala A. The compensatory anti-inflammatory response syndrome (CARS) in critically ill patients. Clin. Chest Med. 2008, 29:617-625. viii.
    • (2008) Clin. Chest Med. , vol.29 , pp. 617-625
    • Ward, N.S.1    Casserly, B.2    Ayala, A.3
  • 65
    • 78651412528 scopus 로고    scopus 로고
    • Immune modulation of learning, memory, neural plasticity and neurogenesis
    • Yirmiya R., Goshen I. Immune modulation of learning, memory, neural plasticity and neurogenesis. Brain Behav. Immun. 2011, 25:181-213.
    • (2011) Brain Behav. Immun. , vol.25 , pp. 181-213
    • Yirmiya, R.1    Goshen, I.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.