Surgery-induced behavioral changes in aged rats

Experimental Gerontology

Volumn 48, Issue 11, 2013, Pages 1204-1211

  Hovens, Iris B ^a   Schoemaker, Regien G ^a   van der Zee, Eddy A ^a   Heineman, Erik ^b   Nyakas, Csaba ^a,c   van Leeuwen, Barbara L ^b  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^c SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

Aging; Cognition; Inflammation; Microglia; Mood; Postoperative cognitive dysfunction; Surgery

Indexed keywords

ADAPTOR PROTEIN; DOUBLECORTIN; INTERLEUKIN 6; IONIZED CALCIUM BINDING ADAPTOR PROTEIN 1; UNCLASSIFIED DRUG;

ABDOMINAL SURGERY; AFFECT; AGED; AGING; ANESTHESIA INDUCTION; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR CHANGE; CELL ACTIVATION; COGNITIVE DEFECT; CONDITIONING; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOKINE RESPONSE; GLIOSIS; HIPPOCAMPAL CA1 REGION; IMMUNOHISTOCHEMISTRY; MALE; MAZE TEST; MICROGLIA; MOOD CHANGE; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; OPEN FIELD TEST; PRIORITY JOURNAL; RAT; SPATIAL LEARNING; WEIGHT REDUCTION;

AGING; AREA UNDER THE CURVE; AUC; BASOLATERAL AMYGDALA; BLA; BOVINE SERUM ALBUMIN; BSA; CA 3; CA1; CFC; COGNITION; CONTEXTUAL FEAR CONDITIONING TEST; CORNU AMMONIS REGION 1; CORNU AMMONIS REGION 3; DCX; DENTATE GYRUS; DENTATE GYRUS INNER BLADE; DG; DGIB; DOUBLECORTIN-X; EDTA; ELEVATED PLUS MAZE; EP; ETHYLENEDIAMINETETRAACETIC ACID; IBA-1; IL-6; INFLAMMATION; INTERLEUKIN 6; IONIZED CALCIUM BINDING ADAPTOR MOLECULE 1; MICROGLIA; MOOD; MORRIS WATER MAZE; MWM; MWM TEST; MWM-T; NORMAL RABBIT SERUM; NRS; PFC; POCD; POLYVINYLPYRROLIDONE; POSTOPERATIVE COGNITIVE DYSFUNCTION; PREFRONTAL CORTEX; PVP; SENSORY MOTOR AREA; SMA; SPONTANEOUS ALTERNATION IN THE Y-MAZE; SURGERY; TRITON-X; TX; Y-MAZE REVERSAL TASK; Y-MAZE SPATIAL REFERENCE TASK; YM; YM-R; YM-S;

AFFECT; AGED; AGING; ANESTHESIA; ANIMALS; BEHAVIOR, ANIMAL; CALCIUM-BINDING PROTEINS; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; HUMANS; INTERLEUKIN-6; MALE; MICROFILAMENT PROTEINS; MICROGLIA; MICROTUBULE-ASSOCIATED PROTEINS; NEUROGENESIS; NEUROPEPTIDES; POSTOPERATIVE COMPLICATIONS; RATS; RATS, WISTAR; WEIGHT LOSS;

EID: 84883823583     PISSN: 05315565     EISSN: 18736815     Source Type: Journal    
DOI: 10.1016/j.exger.2013.07.011     Document Type: Article

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