Poly I: C-induced activation of the immune response is accompanied by depression and anxiety-like behaviours, kynurenine pathway activation and reduced BDNF expression

Brain, Behavior, and Immunity

Volumn 28, Issue , 2013, Pages 170-181

  Gibney, Sinead M ^a   McGuinness, Barry ^a   Prendergast, Christine ^a   Harkin, Andrew ^a   Connor, Thomas J ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

BDNF; Cytokine; Depression; IDO; IL 1; IL 6; Inflammation; Kynurenine; Poly I:C; Serotonin; TNF

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; CD11B ANTIGEN; INDOLEAMINE 2,3 DIOXYGENASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; KYNURENINE; POLYINOSINIC POLYCYTIDYLIC ACID; SACCHARIN; SEROTONIN; TRYPTOPHAN; TUMOR NECROSIS FACTOR ALPHA;

ANHEDONIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANXIETY; ARTICLE; BEHAVIOR CHANGE; CONTROLLED STUDY; DEPRESSION; ENZYME INDUCTION; FOOD PREFERENCE; FRONTAL CORTEX; HIPPOCAMPUS; ILLNESS BEHAVIOR; IMMUNE RESPONSE; LOCOMOTION; MALE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; OPEN FIELD TEST; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; WEIGHT GAIN;

ANIMALS; ANTIGENS, CD11B; ANXIETY; BRAIN-DERIVED NEUROTROPHIC FACTOR; DEPRESSION; FRONTAL LOBE; HIPPOCAMPUS; ILLNESS BEHAVIOR; INTERLEUKIN-1BETA; INTERLEUKIN-6; KYNURENINE; MALE; POLY I-C; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84872198466     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2012.11.010     Document Type: Article

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