A boronate-linked linear-hyperbranched polymeric nanovehicle for pH-dependent tumor-targeted drug delivery

Biomaterials

Volumn 35, Issue 19, 2014, Pages 5240-5249

  Jia, Hui zhen ^a   Zhu, Jun yi ^b   Wang, Xu li ^c   Cheng, Han ^a   Chen, Gang ^b   Zhao, Yi fang ^b   Zeng, Xuan ^a   Feng, Jun ^a   Zhang, Xian zheng ^a   Zhuo, Ren xi ^a  

^a WUHAN UNIVERSITY   (China)

^b Wuhan University   (China)

^c UNIVERSITY OF UTAH   (United States)

Author keywords

Boronate linkage; Dual controlled drug delivery; Nanoassembly; Passive tumor targeting; PH sensitivity

Indexed keywords

CHEMOTHERAPY; CONTROLLED DRUG DELIVERY; DISEASE CONTROL; ENZYME ACTIVITY; IMAGING TECHNIQUES; MEDICAL NANOTECHNOLOGY; MOTION PICTURE EXPERTS GROUP STANDARDS;

ACIDIC MICROENVIRONMENT; BORONATE; NANO-ASSEMBLIES; PH-SENSITIVITY; PHYSIOLOGICAL CONDITION; POST-FUNCTIONALIZATION; TUMOR TARGETING; TUMOR-TARGETED DRUG DELIVERIES;

TUMORS;

BENZENEBORONIC ACID; DOXORUBICIN; MACROGOL; NANOMATERIAL; ANTINEOPLASTIC AGENT; BORONIC ACID DERIVATIVE; DRUG CARRIER; POLYCARBONATE; POLYCARBOXYLATE CEMENT; POLYMER;

ACIDITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CHEMOTHERAPY; CELL SURFACE; CONFOCAL LASER MICROSCOPY; CONJUGATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG RELEASE; ENCAPSULATION; ENDOSOME; HYBRID; HYDROGEN BOND; IN VITRO STUDY; IN VIVO STUDY; INTERNALIZATION; LYSOSOME; MALE; MICROENVIRONMENT; MOUSE; NONHUMAN; PH; PRIORITY JOURNAL; RING OPENING; SUSTAINED DRUG RELEASE; TUMOR CELL; ANIMAL; BAGG ALBINO MOUSE; CHEMICAL PHENOMENA; CHEMISTRY; HELA CELL LINE; HUMAN; NUDE MOUSE; PROCEDURES;

ANIMALS; ANTINEOPLASTIC AGENTS; BORONIC ACIDS; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; HELA CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; POLYCARBOXYLATE CEMENT; POLYMERS;

EID: 84898441065     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2014.03.029     Document Type: Article

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