PEG-detachable and acid-labile cross-linked micelles based on orthoester linked graft copolymer for paclitaxel release

Nanotechnology

Volumn 22, Issue 33, 2011, Pages

  Yuan, Zhefan ^a   Huang, Jingyi ^a   Liu, Jing ^a   Cheng, Sixue ^a   Zhuo, Renxi ^a   Li, Feng ^a  

^a WUHAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACID-LABILE; AMPHIPHILIC COPOLYMERS; CROSS-LINKED MICELLES; CROSSLINKER; HYDROLYSIS RATE; IN-SITU; METHOXY; MILD ACID; PACLITAXEL; PH-DEPENDENT; PHOSPHATE BUFFERS; PHYSIOLOGICAL CONDITION; RELEASE BEHAVIORS;

COPOLYMERIZATION; DIMETHYLFORMAMIDE; GLYCOLS; GRAFT COPOLYMERS; GRAFTING (CHEMICAL); MICELLES; MORPHOLOGY; MOTION PICTURE EXPERTS GROUP STANDARDS; NANOWIRES; POLYETHYLENE OXIDES;

POLYETHYLENE GLYCOLS;

ACID; CROSS LINKING REAGENT; ESTER; MACROGOL DERIVATIVE; PACLITAXEL;

ANIMAL; ARTICLE; CELL DEATH; CELL STRAIN COS1; CERCOPITHECUS; CHEMISTRY; DRUG EFFECT; HYDROLYSIS; INFRARED SPECTROSCOPY; LIGHT; MICELLE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PARTICLE SIZE; PH; POLYMERIZATION; RADIATION SCATTERING; TRANSMISSION ELECTRON MICROSCOPY;

ACIDS; ANIMALS; CELL DEATH; CERCOPITHECUS AETHIOPS; COS CELLS; CROSS-LINKING REAGENTS; ESTERS; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; LIGHT; MAGNETIC RESONANCE SPECTROSCOPY; MICELLES; MICROSCOPY, ELECTRON, TRANSMISSION; PACLITAXEL; PARTICLE SIZE; POLYETHYLENE GLYCOLS; POLYMERIZATION; SCATTERING, RADIATION; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

EID: 79961065924     PISSN: 09574484     EISSN: 13616528     Source Type: Journal    
DOI: 10.1088/0957-4484/22/33/335601     Document Type: Article

References (25)

1. Nasongkla N, Bey E, Ren J, Ai H, Khemtong C, Guthi J S, Chin S-F, Sherry A D, Boothman D A and Gao J 2006 Multifunctional polymeric micelles as cancer-targeted, MRI-ultrasensitive drug delivery systems Nano Lett. 6 2427-30 (Pubitemid 46076928)
2. Lin J, Zhu J, Chen T, Lin S, Cai C, Zhang L, Zhuang Y and Wang X-S 2009 Drug releasing behavior of hybrid micelles containing polypeptide triblock copolymer Biomaterials 30 108-17
3. Zhu Z, Li Y, Li X, Li R, Jia Z, Liu B, Guo W, Wu W and Jiang X 2010 Paclitaxel-loaded poly(N-vinylpyrrolidone)-b-poly([epsilon]-caprolactone) nanoparticles: preparation and antitumor activity in vivo J. Control. Release 142 438-46
4. Lo C-L, Huang C-K, Lin K-M and Hsiue G-H 2007 Mixed micelles formed from graft and diblock copolymers for application in intracellular drug delivery Biomaterials 28 1225-35 (Pubitemid 44809411)
5. Kataoka K, Harada A and Nagasaki Y 2001 Block copolymer micelles for drug delivery: design, characterization and biological significance Adv. Drug Del. Rev. 47 113-31 (Pubitemid 32209236)
6. Matsumura Y and Maeda H 1986 A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs Cancer Res. 46 6387-92 (Pubitemid 17221789)
7. Thurmond K B, Kowalewski T and Wooley K L 1996 Water-soluble knedel-like structures: the preparation of shell-cross-linked small particles J. Am. Chem. Soc. 118 7239-40 (Pubitemid 26261144)
8. Guo A, Liu G and Tao J 1996 Star polymers and nanospheres from cross-linkable diblock copolymers Macromolecules 29 2487-93 (Pubitemid 126597657)
9. Xu P, Tang H, Li S, Ren J, Van Kirk E, Murdoch W J, Radosz M and Shen Y 2004 Enhanced stability of core-surface cross-linked micelles fabricated from amphiphilic brush copolymers Biomacromolecules 5 1736-44 (Pubitemid 39335209)
10. Sun X, Rossin R, Turner J L, Becker M L, Joralemon M J, Welch M J and Wooley K L 2005 An assessment of the effects of shell cross-linked nanoparticle size, core composition, and surface pegylation on in vivo biodistribution Biomacromolecules 6 2541-54 (Pubitemid 41388265)
11. Sun H, Guo B, Cheng R, Meng F, Liu H and Zhong Z 2009 Biodegradable micelles with sheddable poly(ethylene glycol) shells for triggered intracellular release of doxorubicin Biomaterials 30 6358-66
12. Li Y, Du W, Sun G and Wooley K L 2008 pH-responsive shell cross-linked nanoparticles with hydrolytically labile cross-links Macromolecules 41 6605-7
13. Li Y, Lokitz B S, Armes S P and McCormick C L 2006 Synthesis of reversible shell cross-linked micelles for controlled release of bioactive agents Macromolecules 39 2726-8
14. Chan Y, Wong T, Byrne F, Kavallaris M and Bulmus V 2008 Acid-labile core cross-linked micelles for pH-triggered release of antitumor drugs Biomacromolecules 9 1826-36
15. Ding C, Gu J, Qu X and Yang Z 2009 Preparation of multifunctional drug carrier for tumor-specific uptake and enhanced intracellular delivery through the conjugation of weak acid labile linker Bioconjug. Chem. 20 1163-70
16. Li S, Dory Y L and Deslongchamps P 1996 Hydrolysis of cyclic orthoesters: experimental observations and theoretical rationalization Tetrahedron 52 14841-54 (Pubitemid 26390897)
17. Masson C, Garinot M, Mignet N, Wetzer B, Mailhe P, Scherman D and Bessodes M 2004 pH-sensitive PEG lipids containing orthoester linkers: new potential tools for nonviral gene delivery J. Controlled Release 99 423-34 (Pubitemid 39296911)
18. Huang X N, Du F S, Ju R and Li Z C 2007 Novel acid-labile, thermoresponsive poly(methacrylamide)s with pendent ortho ester moieties Macromol. Rapid Commun. 28 597-603 (Pubitemid 47252114)
19. Tang R, Palumbo R N, Ji W and Wang C 2009 Poly(ortho ester amides): acid-labile temperature-responsive copolymers for potential biomedical applications Biomacromolecules 10 722-7
20. Pollak A, Blumenfeld H, Wax M, Baughn R L and Whitesides G M 1980 Enzyme immobilization by condensation copolymerization into crosslinked polyacrylamide gels J. Am. Chem. Soc. 102 6324-36
21. Sun G R, Lee N S, Neumann W L, Freskos J N, Shieh J J, Dorshow R B and Wooley K L 2009 A fundamental investigation of cross-linking efficiencies within discrete nanostructures, using the cross-linker as a reporting molecule Soft Matter 5 3422-9
22. Joralemon M J, O'Reilly R K, Hawker C J and Wooley K L 2005 Shell click-crosslinked (SCC) nanoparticles: a new methodology for synthesis and orthogonal functionalization J. Am. Chem. Soc. 127 16892-9 (Pubitemid 41772849)
23. Tang R, Ji W and Wang C 2010 Amphiphilic block copolymers bearing ortho ester side-chains: pH-dependent hydrolysis and self-assembly in water Macromol. Biosci. 10 192-201
24. By K and Nantz M H 2004 Dioxazocinium ortho esters: a class of highly pH-vulnerable amphiphiles Angew. Chem. Int. Edn 43 1117-20 (Pubitemid 39257973)
25. Chen W, Meng F, Cheng R and Zhong Z Y 2010 pH-sensitive degradable polymersomes for triggered release of anticancer drugs: a comparative study with micelles J. Control. Release 142 40-6