Polypeptide nanogels with hydrophobic moieties in the cross-linked ionic cores: Synthesis, characterization and implications for anticancer drug delivery

Journal of Drug Targeting

Volumn 21, Issue 10, 2013, Pages 981-993

  Kim, Jong Oh ^a,b   Oberoi, Hardeep S ^a   Desale, Swapnil ^a   Kabanov, Alexander V ^a   Bronich, Tatiana K ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b Yeungnam University   (South Korea)

Author keywords

Core shell morphology; Doxorubicin; Nanogel; PEG b poly(l glutamic acid); Phenylalanine

Indexed keywords

COPOLYMER; DOXORUBICIN; PHENYLALANINE METHYL ESTER; POLY(ETHYLENE GLYCOL) B POLY(LEVO GLUTAMIC ACID); POLYPEPTIDE; UNCLASSIFIED DRUG;

ACIDITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CROSS LINKING; DISSOCIATION CONSTANT; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG RELEASE; ELECTROPHORETIC MOBILITY; FEMALE; HUMAN; HUMAN CELL; HYDROGEL; HYDROGEN BOND; HYDROPHOBICITY; MOUSE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; STATIC ELECTRICITY; STEADY STATE; TUMOR XENOGRAFT;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BREAST NEOPLASMS; CROSS-LINKING REAGENTS; DOXORUBICIN; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; FEMALE; GELS; HUMANS; HYDROGEN-ION CONCENTRATION; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MCF-7 CELLS; MICE; NANOPARTICLES; OVARIAN NEOPLASMS; PARTICLE SIZE; PHENYLALANINE; POLYETHYLENE GLYCOLS; POLYGLUTAMIC ACID; POLYMERS; TIME FACTORS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84887256984     PISSN: 1061186X     EISSN: 10292330     Source Type: Journal    
DOI: 10.3109/1061186X.2013.831421     Document Type: Article

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