Distinct effects of IPSU and suvorexant on mouse sleep architecture

Frontiers in Neuroscience

Volumn , Issue 7 DEC, 2013, Pages

  Hoyer, Daniel ^a,b   Dürst, Thomas ^a   Fendt, Markus ^a,c   Jacobson, Laura H ^a,d   Betschart, Claudia ^a   Hintermann, Samuel ^a   Behnke, Dirk ^a   Cotesta, Simona ^a   Laue, Grit ^a   Ofner, Silvio ^a   Legangneux, Eric ^a   Gee, Christine E ^a,e  

^a NOVARTIS PHARMA AG   (Switzerland)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c OTTO VON GUERICKE UNIVERSITY   (Germany)

^d UNIVERSITY OF MELBOURNE   (Australia)

^e Institute for Physiological Chemistry   (Germany)

Author keywords

Insomnia; Orexin receptor antagonist; Pharmacology; REM and NREM sleep

Indexed keywords

2 [(1H INDOL 3 YL)METHYL] 9 (4 METHOXYPYRIMIDIN 2 YL] 2,9 DIAZASPIRO[5.5]UNDECAN 1 ONE; HYPNOTIC SEDATIVE AGENT; OREXIN; OREXIN 1 RECEPTOR; OREXIN 2 RECEPTOR; SUVOREXANT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AROUSAL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG RECEPTOR BINDING; ELECTROENCEPHALOGRAM; ELECTROMYOGRAM; LOCOMOTION; MOUSE; NONHUMAN; NONREM SLEEP; REM SLEEP; SLEEP; SLEEP INDUCTION; SLEEP TIME;

EID: 84898022044     PISSN: 16624548     EISSN: 1662453X     Source Type: Journal    
DOI: 10.3389/fnins.2013.00235     Document Type: Article

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