ABCB1 1199G>A genetic polymorphism (Rs2229109) influences the intracellular accumulation of tacrolimus in HEK293 and K562 recombinant cell lines

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Dessilly, Géraldine ^a   Elens, Laure ^a   Panin, Nadtha ^a   Capron, Arnaud ^b   Decottignies, Anabelle ^c   Demoulin, Jean Baptiste ^c   Haufroid, Vincent ^a,b  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b CLINIQUES UNIVERSITAIRES SAINT LUC   (Belgium)

^c DE DUVE INSTITUTE   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN A; DOXORUBICIN; MULTIDRUG RESISTANCE PROTEIN 1; RHODAMINE 123; TACROLIMUS; VINBLASTINE; ABCB1 PROTEIN, HUMAN; CYCLOSPORIN; MULTIDRUG RESISTANCE PROTEIN; RECOMBINANT DNA;

AMINO ACID SUBSTITUTION; ARTICLE; CELL STRAIN HEK293; CELL STRAIN K 562; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG TRANSPORT; HUMAN; HUMAN CELL; INTRACELLULAR TRANSPORT; SINGLE NUCLEOTIDE POLYMORPHISM; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; HEK293 CELL LINE; INTRACELLULAR SPACE; K562 CELL LINE; METABOLISM; TRANSPORT AT THE CELLULAR LEVEL;

BIOLOGICAL TRANSPORT; CYCLOSPORINE; DNA, RECOMBINANT; DOXORUBICIN; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; INTRACELLULAR SPACE; K562 CELLS; P-GLYCOPROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE; TACROLIMUS; TRANSFECTION; VINBLASTINE;

EID: 84897983523     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0091555     Document Type: Article

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