MDR1 (ABCB1) G1199A (Ser400Asn) polymorphism alters transepithelial permeability and sensitivity to anticancer agents

Cancer Chemotherapy and Pharmacology

Volumn 64, Issue 1, 2009, Pages 183-188

  Woodahl, Erica L ^a,b   Crouthamel, Matthew H ^a   Bui, Tot ^a   Shen, Danny D ^a   Ho, Rodney J Y ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF MONTANA   (United States)

Author keywords

ABCB1; Cancer chemotherapy; MDR1; P Glycoprotein; Pharmacogenomics; Transepithelial permeability

Indexed keywords

ASPARAGINE; DOXORUBICIN; ELACRIDAR; ETOPOSIDE; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN 1; PACLITAXEL; SERINE; VINBLASTINE; VINCRISTINE;

ANIMAL CELL; ARTICLE; CANCER RESISTANCE; CELL MEMBRANE PERMEABILITY; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG PENETRATION; DRUG SENSITIVITY; DRUG TRANSPORT; EPITHELIUM CELL; GENE MUTATION; IN VITRO STUDY; NONHUMAN; PHARMACOGENOMICS; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; WILD TYPE;

ANIMALS; ANTINEOPLASTIC AGENTS; BIOLOGICAL TRANSPORT; CELLS, CULTURED; DRUG RESISTANCE, NEOPLASM; EPITHELIAL CELLS; GENES, MDR; HUMANS; LLC-PK1 CELLS; P-GLYCOPROTEIN; PERMEABILITY; POLYMORPHISM, SINGLE NUCLEOTIDE; SWINE;

EID: 67349191460     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-008-0906-4     Document Type: Article

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