Functional defect caused by the 4544G>A SNP in ABCC2: Potential impact for drug cellular disposition

Pharmacogenetics and Genomics

Volumn 21, Issue 12, 2011, Pages 884-893

  Elens, Laure ^a   Tyteca, Donatienne ^b   Panin, Nadtha ^a   Courtoy, Pierre ^b   Lison, Dominique ^a   Demoulin, Jean Baptiste ^b   Haufroid, Vincent ^a,c  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b DE DUVE INSTITUTE   (Belgium)

^c CLINIQUES UNIVERSITAIRES SAINT LUC   (Belgium)

Author keywords

4544G >A; ABCC2; ATP binding cassette; ATPase activity; lopinavir; pharmacogenetics; single nucleotide polymorphism

Indexed keywords

ADENOSINE TRIPHOSPHATASE; CALCEIN; CARBOXYFLUORESCEIN; LOPINAVIR; VANADIC ACID;

ABCC2 GENE; ALLELE; AMINO ACID SUBSTITUTION; ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; DRUG DISPOSITION; GENE; GENE EXPRESSION; GENE MUTATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; TRANSPORT AT THE CELLULAR LEVEL;

EID: 81055140118     PISSN: 17446872     EISSN: 17446880     Source Type: Journal    
DOI: 10.1097/FPC.0b013e32834d672b     Document Type: Article

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