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Volumn 9, Issue 3, 2014, Pages

Development of a convenient in vivo hepatotoxin assay using a transgenic zebrafish line with liver-specific dsred expression

Author keywords

[No Author keywords available]

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; ACETYLSALICYLIC ACID; ALCOHOL; AMOXICILLIN; ARSENIC ACID; CHLORPHENIRAMINE; DIMETHYLNITROSAMINE; ESTRADIOL; FATTY ACID; ISONIAZID; LINDANE; MEFENAMIC ACID; PARACETAMOL; PHENYLBUTAZONE; RED FLUORESCENT PROTEIN; DANGEROUS GOODS; PHOTOPROTEIN;

EID: 84897983193     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0091874     Document Type: Article
Times cited : (56)

References (75)
  • 1
    • 0027682646 scopus 로고
    • Hepatotoxicity
    • Zimmerman HJ (1993) Hepatotoxicity. Dis Mon 39: 675-787.
    • (1993) Dis Mon , vol.39 , pp. 675-787
    • Zimmerman, H.J.1
  • 3
    • 84862937975 scopus 로고    scopus 로고
    • Comparisons between in vitro whole cell imaging and in vivo zebrafish-based approaches for identifying potential human hepatotoxicants earlier in pharmaceutical development
    • Hill A, Mesens N, Steemans M, Xu JJ, Aleo MD (2012) Comparisons between in vitro whole cell imaging and in vivo zebrafish-based approaches for identifying potential human hepatotoxicants earlier in pharmaceutical development. Drug Metab Rev 44: 127-140.
    • (2012) Drug Metab Rev , vol.44 , pp. 127-140
    • Hill, A.1    Mesens, N.2    Steemans, M.3    Xu, J.J.4    Aleo, M.D.5
  • 5
    • 84878722744 scopus 로고    scopus 로고
    • HepG2 cells simultaneously expressing five P450 enzymes for the screening of hepatotoxicity: Identification of bioactivable drugs and the potential mechanism of toxicity involved
    • Tolosa L, Gomez-Lechon MJ, Perez-Cataldo G, Castell JV, Donato MT (2013) HepG2 cells simultaneously expressing five P450 enzymes for the screening of hepatotoxicity: identification of bioactivable drugs and the potential mechanism of toxicity involved. Arch Toxicol 87: 1115-1127.
    • (2013) Arch Toxicol , vol.87 , pp. 1115-1127
    • Tolosa, L.1    Gomez-Lechon, M.J.2    Perez-Cataldo, G.3    Castell, J.V.4    Donato, M.T.5
  • 7
    • 77956021602 scopus 로고    scopus 로고
    • Biomarkers of alcohol consumption and related liver disease
    • Niemela O, Alatalo P (2010) Biomarkers of alcohol consumption and related liver disease. Scand J Clin Lab Invest 70: 305-312.
    • (2010) Scand J Clin Lab Invest , vol.70 , pp. 305-312
    • Niemela, O.1    Alatalo, P.2
  • 8
    • 84865752315 scopus 로고    scopus 로고
    • Aurora kinase A (AURKA) and never in mitosis gene A-related kinase 6 (NEK6) genes are upregulated in erosive esophagitis and esophageal adenocarcinoma
    • Kasap E, Boyacioglu SO, Korkmaz M, Yuksel ES, Unsal B, et al. (2012) Aurora kinase A (AURKA) and never in mitosis gene A-related kinase 6 (NEK6) genes are upregulated in erosive esophagitis and esophageal adenocarcinoma. Exp Ther Med 4: 33-42.
    • (2012) Exp Ther Med , vol.4 , pp. 33-42
    • Kasap, E.1    Boyacioglu, S.O.2    Korkmaz, M.3    Yuksel, E.S.4    Unsal, B.5
  • 9
    • 43049176656 scopus 로고    scopus 로고
    • Zebrafish: A predictive model for assessing drug-induced toxicity
    • McGrath P, Li CQ (2008) Zebrafish: a predictive model for assessing drug-induced toxicity. Drug Discov Today 13: 394-401.
    • (2008) Drug Discov Today , vol.13 , pp. 394-401
    • McGrath, P.1    Li, C.Q.2
  • 10
    • 43049176656 scopus 로고    scopus 로고
    • Zebrafish: A predictive model for assessing drug-induced toxicity
    • McGrath P, Li CQ (2008) Zebrafish: a predictive model for assessing drug-induced toxicity. Drug Discovery Today 13: 394-401.
    • (2008) Drug Discovery Today , vol.13 , pp. 394-401
    • McGrath, P.1    Li, C.Q.2
  • 11
    • 84873263600 scopus 로고    scopus 로고
    • Fluorescent Transgenic Zebrafish Tg(nkx2.2a:MEGFP) Provides a Highly Sensitive Monitoring Tool for Neurotoxins
    • Zhang X, Gong Z (2013) Fluorescent Transgenic Zebrafish Tg(nkx2.2a:mEGFP) Provides a Highly Sensitive Monitoring Tool for Neurotoxins. PLoS One 8: e55474.
    • (2013) PLoS One , vol.8
    • Zhang, X.1    Gong, Z.2
  • 13
  • 14
    • 77249177588 scopus 로고    scopus 로고
    • Acetaminophen induced acute liver failure via oxidative stress and JNK activation: Protective role of taurine by the suppression of cytochrome P450 2E1
    • Das J, Ghosh J, Manna P, Sil PC (2010) Acetaminophen induced acute liver failure via oxidative stress and JNK activation: protective role of taurine by the suppression of cytochrome P450 2E1. Free Radic Res 44: 340-355.
    • (2010) Free Radic Res , vol.44 , pp. 340-355
    • Das, J.1    Ghosh, J.2    Manna, P.3    Sil, P.C.4
  • 15
    • 0032572572 scopus 로고    scopus 로고
    • Hepatotoxicity of non-narcotic analgesics
    • Tolman KG (1998) Hepatotoxicity of non-narcotic analgesics. Am J Med 105: 13S-19S.
    • (1998) Am J Med , vol.105
    • Tolman, K.G.1
  • 16
    • 34249083462 scopus 로고    scopus 로고
    • Isoniazid induces oxidative stress, mitochondrial dysfunction and apoptosis in Hep G2 cells
    • DOI 10.1170/T781
    • Bhadauria S, Singh G, Sinha N, Srivastava S (2007) Isoniazid induces oxidative stress, mitochondrial dysfunction and apoptosis in Hep G2 cells. Cell Mol Biol (Noisy-le-grand) 53: 102-114. (Pubitemid 46799697)
    • (2007) Cellular and Molecular Biology , vol.53 , Issue.1 , pp. 102-114
    • Bhadauria, S.1    Singh, G.2    Sinha, N.3    Srivastava, S.4
  • 17
    • 77952836903 scopus 로고    scopus 로고
    • Isoniazid-induced apoptosis in HepG2 cells: Generation of oxidative stress and Bcl-2 down-regulation
    • Bhadauria S, Mishra R, Kanchan R, Tripathi C, Srivastava A, et al. (2010) Isoniazid-induced apoptosis in HepG2 cells: generation of oxidative stress and Bcl-2 down-regulation. Toxicol Mech Methods 20: 242-251.
    • (2010) Toxicol Mech Methods , vol.20 , pp. 242-251
    • Bhadauria, S.1    Mishra, R.2    Kanchan, R.3    Tripathi, C.4    Srivastava, A.5
  • 18
    • 18744364709 scopus 로고    scopus 로고
    • Oxidative stress mediated idiosyncratic drug toxicity
    • DOI 10.1081/DMR-200055227
    • Tafazoli S, Spehar DD, O'Brien PJ (2005) Oxidative stress mediated idiosyncratic drug toxicity. Drug Metab Rev 37: 311-325. (Pubitemid 40677507)
    • (2005) Drug Metabolism Reviews , vol.37 , Issue.2 , pp. 311-325
    • Tafazoli, S.1    Spehar, D.D.2    O'Brien, P.J.3
  • 19
    • 0036048386 scopus 로고    scopus 로고
    • DarT: The embryo test with the Zebrafish Danio rerio - A general model in ecotoxicology and toxicology
    • Nagel R (2002) DarT: The embryo test with the Zebrafish Danio rerio - a general model in ecotoxicology and toxicology. ALTEX 19 Suppl 1: 38-48.
    • (2002) ALTEX , vol.19 , Issue.SUPPL. 1 , pp. 38-48
    • Nagel, R.1
  • 20
    • 83655196930 scopus 로고    scopus 로고
    • Liver tumor models in transgenic zebrafish: An alternative in vivo approach to study hepatocarcinogenes
    • Huang X, Zhou L, Gong Z (2012) Liver tumor models in transgenic zebrafish: an alternative in vivo approach to study hepatocarcinogenes. Future Oncol 8: 21-28.
    • (2012) Future Oncol , vol.8 , pp. 21-28
    • Huang, X.1    Zhou, L.2    Gong, Z.3
  • 21
    • 64149097786 scopus 로고    scopus 로고
    • The MIQE guidelines: Minimum information for publication of quantitative real-time PCR experiments
    • Bustin SA, Benes V, Garson JA, Hellemans J, Huggett J, et al. (2009) The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments. Clin Chem 55: 611-622.
    • (2009) Clin Chem , vol.55 , pp. 611-622
    • Bustin, S.A.1    Benes, V.2    Garson, J.A.3    Hellemans, J.4    Huggett, J.5
  • 22
    • 0037404972 scopus 로고    scopus 로고
    • Effects of daily, light and moderate-heavy ethanol exposure on extent of hepatic injury and recovery following toxin-induced acute hepatitis in rats
    • DOI 10.1023/A:1023003730138
    • Zhang M, Uhanova J, Corbin I, Bernstein C, Minuk GY (2003) Effects of daily, light and moderate-heavy ethanol exposure on extent of hepatic injury and recovery following toxin-induced acute hepatitis in rats. Dig Dis Sci 48: 926-931. (Pubitemid 36470214)
    • (2003) Digestive Diseases and Sciences , vol.48 , Issue.5 , pp. 926-931
    • Zhang, M.1    Uhanova, J.2    Corbin, I.3    Bernstein, C.4    Minuk, G.Y.5
  • 24
    • 80054867741 scopus 로고    scopus 로고
    • Molecular investigation of the effects of lindane in rat hepatocytes: Microarray and mechanistic studies
    • Zucchini-Pascal N, de Sousa G, Pizzol J, Rahmani R (2011) Molecular investigation of the effects of lindane in rat hepatocytes: microarray and mechanistic studies. Food Chem Toxicol 49: 3128-3135.
    • (2011) Food Chem Toxicol , vol.49 , pp. 3128-3135
    • Zucchini-Pascal, N.1    De Sousa, G.2    Pizzol, J.3    Rahmani, R.4
  • 25
    • 84883807669 scopus 로고    scopus 로고
    • Toxicity assessments of nonsteroidal anti-inflammatory drugs in isolated mitochondria, rat hepatocytes, and zebrafish show good concordance across chemical classes
    • Nadanaciva S, Aleo MD, Strock CJ, Stedman DB, Wang H, et al. (2013) Toxicity assessments of nonsteroidal anti-inflammatory drugs in isolated mitochondria, rat hepatocytes, and zebrafish show good concordance across chemical classes. Toxicol Appl Pharmacol 272: 272-280.
    • (2013) Toxicol Appl Pharmacol , vol.272 , pp. 272-280
    • Nadanaciva, S.1    Aleo, M.D.2    Strock, C.J.3    Stedman, D.B.4    Wang, H.5
  • 26
    • 9444229982 scopus 로고    scopus 로고
    • Liver injury induced by the non-steroidal anti-inflammatory drug mefenamic acid
    • Somchit N, Sanat F, Gan EH, Shahrin IA, Zuraini A (2004) Liver injury induced by the non-steroidal anti-inflammatory drug mefenamic acid. Singapore Med J 45: 530-532. (Pubitemid 39564032)
    • (2004) Singapore Medical Journal , vol.45 , Issue.11 , pp. 530-532
    • Somchit, N.1    Sanat, F.2    Gan, E.H.3    Shahrin, I.A.W.4    Zuraini, A.5
  • 27
    • 84867856153 scopus 로고    scopus 로고
    • Arsenic-induced biochemical and genotoxic effects and distribution in tissues of Sprague-Dawley rats
    • Patlolla AK, Todorov TI, Tchounwou PB, van der Voet G, Centeno JA (2012) Arsenic-induced biochemical and genotoxic effects and distribution in tissues of Sprague-Dawley rats. Microchem J 105: 101-107.
    • (2012) Microchem J , vol.105 , pp. 101-107
    • Patlolla, A.K.1    Todorov, T.I.2    Tchounwou, P.B.3    Van Der Voet, G.4    Centeno, J.A.5
  • 28
    • 80052702882 scopus 로고    scopus 로고
    • Mechanisms pertaining to arsenic toxicity
    • Singh AP, Goel RK, Kaur T (2011) Mechanisms pertaining to arsenic toxicity. Toxicol Int 18: 87-93.
    • (2011) Toxicol Int , vol.18 , pp. 87-93
    • Singh, A.P.1    Goel, R.K.2    Kaur, T.3
  • 29
    • 80051799928 scopus 로고    scopus 로고
    • Estrogen Stimulates Proliferation and Differentiation of Neural Stem/Progenitor Cells through Different Signal Transduction Pathways
    • Okada M, Makino A, Nakajima M, Okuyama S, Furukawa S, et al. (2010) Estrogen Stimulates Proliferation and Differentiation of Neural Stem/Progenitor Cells through Different Signal Transduction Pathways. Int J Mol Sci 11: 4114-4123.
    • (2010) Int J Mol Sci , vol.11 , pp. 4114-4123
    • Okada, M.1    Makino, A.2    Nakajima, M.3    Okuyama, S.4    Furukawa, S.5
  • 30
    • 0036813338 scopus 로고    scopus 로고
    • Similar mechanisms of fatty acid transfer from human anal rodent fatty acid-binding proteins to membranes: Liver, intestine, heart muscle and adipose tissue FABPs
    • DOI 10.1023/A:1020546321508
    • Storch J, Veerkamp JH, Hsu KT (2002) Similar mechanisms of fatty acid transfer from human anal rodent fatty acid-binding proteins to membranes: liver, intestine, heart muscle, and adipose tissue FABPs. Mol Cell Biochem 239: 25-33. (Pubitemid 35385792)
    • (2002) Molecular and Cellular Biochemistry , vol.239 , Issue.1-2 , pp. 25-33
    • Storch, J.1    Veerkamp, J.H.2    Hsu, K.-T.3
  • 31
    • 82255195413 scopus 로고    scopus 로고
    • Existence of inverted profile in chemically responsive molecular pathways in the zebrafish liver
    • Ung CY, Lam SH, Zhang X, Li H, Ma J, et al. (2011) Existence of inverted profile in chemically responsive molecular pathways in the zebrafish liver. PLoS One 6: e27819.
    • (2011) PLoS One , vol.6
    • Ung, C.Y.1    Lam, S.H.2    Zhang, X.3    Li, H.4    Ma, J.5
  • 32
    • 78049314065 scopus 로고    scopus 로고
    • PGE2-regulated wnt signaling and N-acetylcysteine are synergistically hepatoprotective in zebrafish acetaminophen injury
    • North TE, Babu IR, Vedder LM, Lord AM, Wishnok JS, et al. (2010) PGE2-regulated wnt signaling and N-acetylcysteine are synergistically hepatoprotective in zebrafish acetaminophen injury. Proc Natl Acad Sci U S A 107: 17315-17320.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 17315-17320
    • North, T.E.1    Babu, I.R.2    Vedder, L.M.3    Lord, A.M.4    Wishnok, J.S.5
  • 33
    • 84884039709 scopus 로고    scopus 로고
    • Chlorpheniramine
    • Editors-in-Chief: SJE, David BB, editors. New York: Elsevier
    • Minigh J (2008) Chlorpheniramine. In: Editors-in-Chief: SJE, David BB, editors. xPharm: The Comprehensive Pharmacology Reference. New York: Elsevier. 1-6.
    • (2008) xPharm: The Comprehensive Pharmacology Reference , pp. 1-6
    • Minigh, J.1
  • 35
    • 84882516408 scopus 로고    scopus 로고
    • Chapter 16 - NSAIDs and COX-2-Selective Inhibitors
    • Honorio TB, Md, Srinivasa NR, Robert EM, Spencer SL et al., editors. (Second Edition). Philadelphia: Churchill Livingstone
    • Katz JA (2005) Chapter 16 - NSAIDs and COX-2-Selective Inhibitors. In: Honorio TB, Md, Srinivasa NR, Robert EM, Spencer SL et al., editors. Essentials of Pain Medicine and Regional Anesthesia (Second Edition). Philadelphia: Churchill Livingstone. 141-158.
    • (2005) Essentials of Pain Medicine and Regional Anesthesia , pp. 141-158
    • Katz, J.A.1
  • 36
    • 38449123465 scopus 로고    scopus 로고
    • Idiosyncratic drug-induced liver injury: An overview
    • DOI 10.1517/14740338.6.6.673
    • Hussaini SH, Farrington EA (2007) Idiosyncratic drug-induced liver injury: an overview. Expert Opinion on Drug Safety 6: 673-684. (Pubitemid 351308279)
    • (2007) Expert Opinion on Drug Safety , vol.6 , Issue.6 , pp. 673-684
    • Hussaini, S.H.1    Farrington, E.A.2
  • 37
    • 79952446700 scopus 로고    scopus 로고
    • Hepatotoxicity related to antirheumatic drugs
    • Aithal GP (2011) Hepatotoxicity related to antirheumatic drugs. Nature reviews Rheumatology 7: 139-150.
    • (2011) Nature Reviews Rheumatology , vol.7 , pp. 139-150
    • Aithal, G.P.1
  • 41
    • 84872674812 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs and leukotriene receptor antagonists: Pathology and clinical presentation of hepatotoxicity
    • Kaplowitz N, DeLeve LD, editors. 2nd ed. New York: Informa Healthcare
    • Lewis JH (2007) Nonsteroidal anti-inflammatory drugs and leukotriene receptor antagonists: pathology and clinical presentation of hepatotoxicity. In: Kaplowitz N, DeLeve LD, editors. Drug-induced liver disease. 2nd ed. New York: Informa Healthcare. 440-464.
    • (2007) Drug-induced Liver Disease , pp. 440-464
    • Lewis, J.H.1
  • 42
    • 9444229982 scopus 로고    scopus 로고
    • Liver injury induced by the non-steroidal anti-inflammatory drug mefenamic acid
    • Somchit N, Sanat F, Gan EH, Shahrin IA, Zuraini A (2004) Liver injury induced by the non-steroidal anti-inflammatory drug mefenamic acid. Singapore medical journal 45: 530-532. (Pubitemid 39564032)
    • (2004) Singapore Medical Journal , vol.45 , Issue.11 , pp. 530-532
    • Somchit, N.1    Sanat, F.2    Gan, E.H.3    Shahrin, I.A.W.4    Zuraini, A.5
  • 43
    • 80053133051 scopus 로고    scopus 로고
    • Atherosclerosis induced by arsenic in drinking water in rats through altering lipid metabolism
    • Cheng TJ, Chuu JJ, Chang CY, Tsai WC, Chen KJ, et al. (2011) Atherosclerosis induced by arsenic in drinking water in rats through altering lipid metabolism. Toxicol Appl Pharmacol 256: 146-153.
    • (2011) Toxicol Appl Pharmacol , vol.256 , pp. 146-153
    • Cheng, T.J.1    Chuu, J.J.2    Chang, C.Y.3    Tsai, W.C.4    Chen, K.J.5
  • 44
    • 84902317433 scopus 로고    scopus 로고
    • Arsenic exposure alters expression of cell cycle and lipid metabolism genes in the liver of adult zebrafish (Danio rerio)
    • Carlson P, Van Beneden RJ (2013) Arsenic exposure alters expression of cell cycle and lipid metabolism genes in the liver of adult zebrafish (Danio rerio). Aquat Toxicol.
    • (2013) Aquat Toxicol
    • Carlson, P.1    Van Beneden, R.J.2
  • 46
    • 84880275240 scopus 로고    scopus 로고
    • Proteomic analysis of arsenic-exposed zebrafish (Danio rerio) identifies altered expression in proteins involved in fibrosis and lipid uptake in a gender-specific manner
    • Carlson P, Smalley DM, Van Beneden RJ (2013) Proteomic analysis of arsenic-exposed zebrafish (Danio rerio) identifies altered expression in proteins involved in fibrosis and lipid uptake in a gender-specific manner. Toxicol Sci 134: 83-91.
    • (2013) Toxicol Sci , vol.134 , pp. 83-91
    • Carlson, P.1    Smalley, D.M.2    Van Beneden, R.J.3
  • 47
  • 48
    • 84859110523 scopus 로고    scopus 로고
    • Lindane toxicity: A comprehensive review of the medical literature
    • Nolan K, Kamrath J, Levitt J (2012) Lindane toxicity: a comprehensive review of the medical literature. Pediatric dermatology 29: 141-146.
    • (2012) Pediatric Dermatology , vol.29 , pp. 141-146
    • Nolan, K.1    Kamrath, J.2    Levitt, J.3
  • 50
    • 0029137925 scopus 로고
    • The effect of gamma-hexachlorocyclohexane (lindane) on the activities of liver lipogenic enzymes and on serum lipids in rats
    • Boll M, Weber L, Stampfl A (1995) The effect of gamma- hexachlorocyclohexane (lindane) on the activities of liver lipogenic enzymes and on serum lipids in rats. Zeitschrift für Naturforschung C, Journal of biosciences 50: 135.
    • (1995) Zeitschrift für Naturforschung C, Journal of Biosciences , vol.50 , pp. 135
    • Boll, M.1    Weber, L.2    Stampfl, A.3
  • 52
    • 84872442941 scopus 로고    scopus 로고
    • Differential effects of estrogen/androgen on the prevention of nonalcoholic fatty liver disease in the male rat
    • Zhang H, Liu Y, Wang L, Li Z, Wu J, et al. (2013) Differential effects of estrogen/androgen on the prevention of nonalcoholic fatty liver disease in the male rat. Journal of lipid research 54: 345-357.
    • (2013) Journal of Lipid Research , vol.54 , pp. 345-357
    • Zhang, H.1    Liu, Y.2    Wang, L.3    Li, Z.4    Wu, J.5
  • 53
    • 1642505593 scopus 로고    scopus 로고
    • Estrogen replacement reverses the hepatic steatosis phenotype in the male aromatase knockout mouse
    • DOI 10.1210/en.2003-1369
    • Hewitt KN, Pratis K, Jones ME, Simpson ER (2004) Estrogen replacement reverses the hepatic steatosis phenotype in the male aromatase knockout mouse. Endocrinology 145: 1842-1848. (Pubitemid 38402393)
    • (2004) Endocrinology , vol.145 , Issue.4 , pp. 1842-1848
    • Hewitt, K.N.1    Pratis, K.2    Jones, M.E.E.3    Simpson, E.R.4
  • 55
    • 33750297793 scopus 로고    scopus 로고
    • Carcinogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in experimental models
    • DOI 10.1002/mnfr.200600006
    • Knerr S, Schrenk D (2006) Carcinogenicity of 2,3,7,8-tetrachlorodibenzo- p-dioxin in experimental models. Mol Nutr Food Res 50: 897-907. (Pubitemid 44621795)
    • (2006) Molecular Nutrition and Food Research , vol.50 , Issue.10 , pp. 897-907
    • Knerr, S.1    Schrenk, D.2
  • 56
    • 0028951478 scopus 로고
    • Correlation between toxicity and effects on intermediary metabolism in 2,3,7,8-tetrachlo-rodibenzo-p-dioxin-treated male C57BL/6J and DBA/2J mice
    • Weber LW, Lebofsky M, Stahl BU, Smith S, Rozman KK (1995) Correlation between toxicity and effects on intermediary metabolism in 2,3,7,8-tetrachlo- rodibenzo-p-dioxin-treated male C57BL/6J and DBA/2J mice. Toxicol Appl Pharmacol 131: 155-162.
    • (1995) Toxicol Appl Pharmacol , vol.131 , pp. 155-162
    • Weber, L.W.1    Lebofsky, M.2    Stahl, B.U.3    Smith, S.4    Rozman, K.K.5
  • 57
    • 0029893731 scopus 로고    scopus 로고
    • Promotion of endometriosis by 2,3,7,8-tetrachlorodibenzo-p-dioxin in rats and mice: Time-Dose dependence and species comparison
    • DOI 10.1006/taap.1996.0106
    • Cummings AM, Metcalf JL, Birnbaum L (1996) Promotion of endometriosis by 2,3,7,8-tetrachlorodibenzo-p-dioxin in rats and mice: time-dose dependence and species comparison. Toxicol Appl Pharmacol 138: 131-139. (Pubitemid 26159603)
    • (1996) Toxicology and Applied Pharmacology , vol.138 , Issue.1 , pp. 131-139
    • Cummings, A.M.1    Metcalf, J.L.2    Birnbaum, L.3
  • 58
    • 0030844316 scopus 로고    scopus 로고
    • Altered in vivo toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in c-src deficient mice
    • DOI 10.1016/S0006-2952(97)00036-1, PII S0006295297000361
    • Matsumura F, Enan E, Dunlap DY, Pinkerton KE, Peake J (1997) Altered in vivo toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in C-SRC deficient mice. Biochem Pharmacol 53: 1397-1404. (Pubitemid 27356110)
    • (1997) Biochemical Pharmacology , vol.53 , Issue.10 , pp. 1397-1404
    • Matsumura, F.1    Enan, E.2    Dunlap, D.Y.3    Pinkerton, K.E.4    Peake, J.5
  • 59
    • 36248946661 scopus 로고    scopus 로고
    • Occurrence, genotoxicity, and carcinogenicity of regulated and emerging disinfection by-products in drinking water: A review and roadmap for research
    • DOI 10.1016/j.mrrev.2007.09.001, PII S138357420700035X, The Sources and Potential Hazards of Mutagens in Complex Environmental Matrices - Part II
    • Richardson SD, Plewa MJ, Wagner ED, Schoeny R, Demarini DM (2007) Occurrence, genotoxicity, and carcinogenicity of regulated and emerging disinfection by-products in drinking water: a review and roadmap for research. Mutat Res 636: 178-242. (Pubitemid 350130339)
    • (2007) Mutation Research - Reviews in Mutation Research , vol.636 , Issue.1-3 , pp. 178-242
    • Richardson, S.D.1    Plewa, M.J.2    Wagner, E.D.3    Schoeny, R.4    DeMarini, D.M.5
  • 60
    • 4544370541 scopus 로고    scopus 로고
    • Carcinogenic effect of N-nitrosodimethylamine on diploid and triploid Zebrafish (Danio rerio)
    • DOI 10.1080/01926230490496311
    • Mizgireuv IV, Majorova IG, Gorodinskaya VM, Khudoley VV, Revskoy SY (2004) Carcinogenic effect of N-nitrosodimethylamine on diploid and triploid zebrafish (Danio rerio). Toxicologic pathology 32: 514-518. (Pubitemid 39258456)
    • (2004) Toxicologic Pathology , vol.32 , Issue.5 , pp. 514-518
    • Mizgireuv, I.V.1    Majorova, I.G.2    Gorodinskaya, V.M.3    Khudoley, V.V.4    Revskoy, S.Y.5
  • 61
    • 0343987530 scopus 로고
    • Induction of Liver Tumors in the Syrian Golden Hamster by Feeding Dimethylnitrosamine
    • Tomatis L, Magee PN, Shubik P (1964) Induction of Liver Tumors in the Syrian Golden Hamster by Feeding Dimethylnitrosamine. J Natl Cancer Inst 33: 341-345.
    • (1964) J Natl Cancer Inst , vol.33 , pp. 341-345
    • Tomatis, L.1    Magee, P.N.2    Shubik, P.3
  • 63
    • 84874529776 scopus 로고    scopus 로고
    • Urinary and serum biomarkers for the diagnosis of acute kidney injury: An in-depth review of the literature
    • Vanmassenhove J, Vanholder R, Nagler E, Van Biesen W (2013) Urinary and serum biomarkers for the diagnosis of acute kidney injury: an in-depth review of the literature. Nephrol Dial Transplant 28: 254-273.
    • (2013) Nephrol Dial Transplant , vol.28 , pp. 254-273
    • Vanmassenhove, J.1    Vanholder, R.2    Nagler, E.3    Van Biesen, W.4
  • 65
    • 33645305405 scopus 로고    scopus 로고
    • Modeling liver cancer using zebrafish - A comparative oncogenomics approach
    • Lam SH, Gong ZY (2006) Modeling liver cancer using zebrafish - A comparative oncogenomics approach. Cell Cycle 5: 573-577.
    • (2006) Cell Cycle , vol.5 , pp. 573-577
    • Lam, S.H.1    Gong, Z.Y.2
  • 68
    • 47749130062 scopus 로고    scopus 로고
    • Uncovering genes with divergent mRNA-protein dynamics in Streptomyces coelicolor
    • Jayapal KP, Philp RJ, Kok YJ, Yap MG, Sherman DH, et al. (2008) Uncovering genes with divergent mRNA-protein dynamics in Streptomyces coelicolor. PloS one 3: e2097.
    • (2008) PloS One , vol.3
    • Jayapal, K.P.1    Philp, R.J.2    Kok, Y.J.3    Yap, M.G.4    Sherman, D.H.5
  • 69
    • 71149108056 scopus 로고    scopus 로고
    • Correlation of mRNA and protein in complex biological samples
    • Maier T, Guell M, Serrano L (2009) Correlation of mRNA and protein in complex biological samples. FEBS letters 583: 3966-3973.
    • (2009) FEBS Letters , vol.583 , pp. 3966-3973
    • Maier, T.1    Guell, M.2    Serrano, L.3
  • 71
    • 84855946372 scopus 로고    scopus 로고
    • In vivo imaging and quantitative analysis of changes in axon length using transgenic zebrafish embryos
    • Kanungo J, Lantz S, Paule MG (2011) In vivo imaging and quantitative analysis of changes in axon length using transgenic zebrafish embryos. Neurotoxicology and teratology 33: 618-623.
    • (2011) Neurotoxicology and Teratology , vol.33 , pp. 618-623
    • Kanungo, J.1    Lantz, S.2    Paule, M.G.3
  • 72
    • 84855946372 scopus 로고    scopus 로고
    • In vivo imaging and quantitative analysis of changes in axon length using transgenic zebrafish embryos
    • Kanungo J, Lantz S, Paule MG (2011) In vivo imaging and quantitative analysis of changes in axon length using transgenic zebrafish embryos. Neurotoxicol Teratol 33: 618-623.
    • (2011) Neurotoxicol Teratol , vol.33 , pp. 618-623
    • Kanungo, J.1    Lantz, S.2    Paule, M.G.3
  • 73
    • 4344645978 scopus 로고    scopus 로고
    • Can the pharmaceutical industry reduce attrition rates?
    • Kola I, Landis J (2004) Can the pharmaceutical industry reduce attrition rates? Nature Reviews Drug Discovery 3: 711-715. (Pubitemid 39173511)
    • (2004) Nature Reviews Drug Discovery , vol.3 , Issue.8 , pp. 711-715
    • Kola, I.1    Landis, J.2
  • 74
    • 84857361302 scopus 로고    scopus 로고
    • A critical evaluation of in vitro cell culture models for high-throughput drug screening and toxicity
    • Astashkina A, Mann B, Grainger DW (2012) A critical evaluation of in vitro cell culture models for high-throughput drug screening and toxicity. Pharmacology & therapeutics 134: 82-106.
    • (2012) Pharmacology & Therapeutics , vol.134 , pp. 82-106
    • Astashkina, A.1    Mann, B.2    Grainger, D.W.3
  • 75
    • 80052925417 scopus 로고    scopus 로고
    • Animal models of idiosyncratic drug-induced liver injury-Current status
    • Roth RA, Ganey PE (2011) Animal models of idiosyncratic drug-induced liver injury-Current status. Critical Reviews in Toxicology 41: 723-739.
    • (2011) Critical Reviews in Toxicology , vol.41 , pp. 723-739
    • Roth, R.A.1    Ganey, P.E.2


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