Tanshinone IIA promotes pulmonary artery smooth muscle cell apoptosis in vitro by inhibiting the JAK2/STAT3 signaling pathway

Cellular Physiology and Biochemistry

Volumn 33, Issue 4, 2014, Pages 1130-1138

  Chen, Minggang ^a   Liu, Yumei ^a   Yi, Dan ^a   Wei, Liuping ^a   Li, Yumei ^a,b   Zhang, Li ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b Biopharmaceutical Institute   (China)

Author keywords

Apoptosis; Cx43; JAK2 STAT3; PASMCs; Tanshinone IIA

Indexed keywords

CASPASE 3; CHAPERONIN 60; JANUS KINASE 2; LIPOCORTIN 5; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; PROPIDIUM IODIDE; STAT3 PROTEIN; TANSHINONE IIA; ABIETANE DERIVATIVE; ANTINEOPLASTIC AGENT; CONNEXIN 43; TANSHINONE; BIOLOGICAL MARKER;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTERIAL WALL THICKNESS; ARTICLE; CELL DEATH; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; COMPARATIVE STUDY; CONTROLLED STUDY; DOSE RESPONSE; FLOW CYTOMETRY; FLUORESCENCE; GAP JUNCTION; HYPOXIA; IN VITRO STUDY; LUNG BLOOD VESSEL; LUNG PARENCHYMA; MALE; MTT ASSAY; NONHUMAN; PRIMARY CELL CULTURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PULMONARY ARTERY; PULMONARY ARTERY SMOOTH MUSCLE CELL; PULMONARY HYPERTENSION; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; UPREGULATION; WESTERN BLOTTING; ANIMAL; CELL CULTURE; CELL HYPOXIA; CYTOLOGY; DRUG EFFECTS; METABOLISM; PHOSPHORYLATION; VASCULAR REMODELING; WISTAR RAT; ENZYME PHOSPHORYLATION; QUANTITATIVE ANALYSIS;

RATTUS;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CASPASE 3; CELL HYPOXIA; CELLS, CULTURED; CHAPERONIN 60; CONNEXIN 43; DITERPENES, ABIETANE; JANUS KINASE 2; MALE; MYOCYTES, SMOOTH MUSCLE; PHOSPHORYLATION; PULMONARY ARTERY; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; UP-REGULATION; VASCULAR REMODELING;

EID: 84897966464     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000358682     Document Type: Article

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