Analysis of tanshinone IIA induced cellular apoptosis in leukemia cells by genome-wide expression profiling

BMC Complementary and Alternative Medicine

Volumn 12, Issue , 2012, Pages

  Liu, Chang ^a   Li, Jianqin ^a   Wang, Liangjie ^d   Wu, Fuqun ^b   Huang, Linfang ^a   Xu, Yue ^b,c   Ye, Jieyu ^b   Xiao, Bin ^b,c   Meng, Fanyi ^b   Chen, Shilin ^a   Yang, Mo ^b,d  

^a INSTITUTE OF MEDICINAL PLANT DEVELOPMENT   (China)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

^c MEDICAL COLLEGE OF JINAN UNIVERSITY   (China)

^d UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Apoptosis; CCL2; Gene expression profiling; Tanshinone IIA (Tan IIA); U 937 cell lines

Indexed keywords

BIRC5 PROTEIN; CASPASE 3; CELL PROTEIN; HSPA1A PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; PRKCZ PROTEIN; PROTEIN BCL 2; SERPINB2 PROTEIN; SURVIVIN; TANSHINONE IIA; UNCLASSIFIED DRUG; ABIETANE DERIVATIVE; ANTINEOPLASTIC AGENT; CCL2 PROTEIN, HUMAN; PLANT EXTRACT; PREGNANE X RECEPTOR; STEROID RECEPTOR; SULFORAFAN; TANSHINONE; THIOCYANIC ACID DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL CYCLE REGULATION; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG SCREENING; ENZYME ACTIVITY; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IN VITRO STUDY; LEUKEMIA CELL; NUCLEOTIDE SEQUENCE; CELL STRAIN U937; CHEMISTRY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION PROFILING; GENETIC ASSOCIATION; GENETICS; LEUKEMIA; METABOLISM; METHODOLOGY; PHYTOTHERAPY; PLANT ROOT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SALVIA MILTIORRHIZA; TUMOR CELL LINE; TUMOR GENE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL LINE, TUMOR; CHEMOKINE CCL2; DITERPENES, ABIETANE; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, LEUKEMIC; GENES, NEOPLASM; GENOME-WIDE ASSOCIATION STUDY; HUMANS; LEUKEMIA; PHYTOTHERAPY; PLANT EXTRACTS; PLANT ROOTS; RECEPTORS, STEROID; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SALVIA MILTIORRHIZA; THIOCYANATES; U937 CELLS;

EID: 84855805093     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/1472-6882-12-5     Document Type: Article

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