Correction: Tanshinone iia inhibits hypoxia-induced pulmonary artery smooth muscle cell proliferation via Akt/Skp2/p27-associated pathway (PLoS ONE (2013) 8:2 (e56774) DOI: 10.1371/journal.pone.0056774);Tanshinone IIA Inhibits Hypoxia-Induced Pulmonary Artery Smooth Muscle Cell Proliferation via Akt/Skp2/p27-Associated Pathway

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Luo, Ying ^a,b   Xu, Dun Quan ^b   Dong, Hai Ying ^b   Zhang, Bo ^b   Liu, Yi ^b   Niu, Wen ^b   Dong, Ming Qing ^b   Li, Zhi Chao ^a,b  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; PROTEIN KINASE B; PROTEIN P27; S PHASE KINASE ASSOCIATED PROTEIN 2; SMALL INTERFERING RNA; TANSHINONE IIA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL CYCLE G0 PHASE; CELL PROLIFERATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; FLOW CYTOMETRY; G1 PHASE CELL CYCLE CHECKPOINT; GENE EXPRESSION; HYPOXIA INDUCED PULMONARY HYPERTENSION; LUNG ALVEOLUS CELL; MALE; NONHUMAN; P27 GENE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PULMONARY ARTERY; PULMONARY ARTERY SMOOTH MUSCLE CELL; PULMONARY HYPERTENSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; S PHASE KINASE ASSOCIATED PROTEIN 2 GENE; SIGNAL TRANSDUCTION; TREATMENT DURATION; UPREGULATION; WESTERN BLOTTING;

EID: 84874298451     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0108753     Document Type: Erratum

References (44)

1. Stenmark KR, Fagan KA, Frid MG, (2006) Hypoxia-induced pulmonary vascular remodeling: cellular and molecular mechanisms. Circ Res 99: 675-691.
2. Zakynthinos E, Daniil Z, Papanikolaou J, Makris D, (2011) Pulmonary hypertension in COPD: pathophysiology and therapeutic targets. Curr Drug Targets 12: 501-513.
3. Pak O, Aldashev A, Welsh D, Peacock A, (2007) The effects of hypoxia on the cells of the pulmonary vasculature. Eur Respir J 30: 364-372.
4. Yu L, Quinn DA, Garg HG, Hales CA, (2006) Gene expression of cyclin-dependent kinase inhibitors and effect of heparin on their expression in mice with hypoxia-induced pulmonary hypertension. Biochem Biophys Res Commun 345: 1565-1572.
5. Toyoshima H, Hunter T, (1994) p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21. Cell 78: 67-74.
6. Fouty BW, Grimison B, Fagan KA, Le Cras TD, Harral JW, et al. (2001) p27(Kip1) is important in modulating pulmonary artery smooth muscle cell proliferation. Am J Respir Cell Mol Biol 25: 652-658.
7. Vervoorts J, Luscher B, (2008) Post-translational regulation of the tumor suppressor p27(KIP1). Cell Mol Life Sci 65: 3255-3264.
8. Slingerland J, Pagano M, (2000) Regulation of the cdk inhibitor p27 and its deregulation in cancer. J Cell Physiol 183: 10-17.
9. Carrano AC, Pagano M, (2001) Role of the F-box protein Skp2 in adhesion-dependent cell cycle progression. J Cell Biol 153: 1381-1390.
10. Zhou L, Zuo Z, Chow MS, (2005) Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use. J Clin Pharmacol 45: 1345-1359.
11. Shang Q, Xu H, Huang L, (2012) Tanshinone IIA: A Promising Natural Cardioprotective Agent. Evid Based Complement Alternat Med 2012: 716459.
12. Huang YF, Liu ML, Dong MQ, Yang WC, Zhang B, et al. (2009) Effects of sodium tanshinone II A sulphonate on hypoxic pulmonary hypertension in rats in vivo and on Kv2.1 expression in pulmonary artery smooth muscle cells in vitro. J Ethnopharmacol 125: 436-443.
13. Wang J, Dong MQ, Liu ML, Xu DQ, Luo Y, et al. (2010) Tanshinone IIA modulates pulmonary vascular response to agonist and hypoxia primarily via inhibiting Ca2+ influx and release in normal and hypoxic pulmonary hypertension rats. Eur J Pharmacol 640: 129-138.
14. Yu L, Quinn DA, Garg HG, Hales CA, (2005) Cyclin-dependent kinase inhibitor p27Kip1, but not p21WAF1/Cip1, is required for inhibition of hypoxia-induced pulmonary hypertension and remodeling by heparin in mice. Circ Res 97: 937-945.
15. Huang YF, Liu ML, Dong MQ, Yang WC, Zhang B, et al. (2009) Effects of sodium tanshinone II A sulphonate on hypoxic pulmonary hypertension in rats in vivo and on Kv2.1 expression in pulmonary artery smooth muscle cells in vitro. J Ethnopharmacol 125: 436-443.
16. Gao S, Liu Z, Li H, Little PJ, Liu P, et al. (2012) Cardiovascular actions and therapeutic potential of tanshinone IIA. Atherosclerosis 220: 3-10.
17. Wang J, Jiang Q, Wan L, Yang K, Zhang Y, et al. (2012) Sodium Tanshinone IIA Sulfonate Inhibits Canonical Transient Receptor Potential Expression in Pulmonary Arterial Smooth Muscle from Pulmonary Hypertensive Rats. Am J Respir Cell Mol Biol.
18. Sung HJ, Choi SM, Yoon Y, An KS, (1999) Tanshinone IIA, an ingredient of Salvia miltiorrhiza BUNGE, induces apoptosis in human leukemia cell lines through the activation of caspase-3. Exp Mol Med 31: 174-178.
19. Chan P, Liu JC, Lin LJ, Chen PY, Cheng TH, et al. (2011) Tanshinone IIA inhibits angiotensin II-induced cell proliferation in rat cardiac fibroblasts. Am J Chin Med 39: 381-394.
20. Chen J, Shi DY, Liu SL, Zhong L, (2012) Tanshinone IIA induces growth inhibition and apoptosis in gastric cancer in vitro and in vivo. Oncol Rep 27: 523-528.
21. HONG HJ, LIU JC, CHENG TH, CHAN P, (2010) Tanshinone IIA attenuates angiotensin II-induced apoptosis via Akt pathway in neonatal rat cardiomyocytes. Acta Pharmacol Sin 31: 1569-1575.
22. Li FL, Xu R, Zeng QC, Li X, Chen J, et al. (2012) Tanshinone IIA Inhibits Growth of Keratinocytes through Cell Cycle Arrest and Apoptosis: Underlying Treatment Mechanism of Psoriasis. Evid Based Complement Alternat Med 2012: 927658.
23. Won SH, Lee HJ, Jeong SJ, Lee HJ, Lee EO, et al. (2010) Tanshinone IIA induces mitochondria dependent apoptosis in prostate cancer cells in association with an inhibition of phosphoinositide 3-kinase/AKT pathway. Biol Pharm Bull 33: 1828-1834.
24. Zhang Y, Wei RX, Zhu XB, Cai L, Jin W, et al. (2012) Tanshinone IIA induces apoptosis and inhibits the proliferation, migration, and invasion of the osteosarcoma MG-63 cell line in vitro. Anticancer Drugs 23: 212-219.
25. Zhou L, Chan WK, Xu N, Xiao K, Luo H, et al. (2008) Tanshinone IIA, an isolated compound from Salvia miltiorrhiza Bunge, induces apoptosis in HeLa cells through mitotic arrest. Life Sci 83: 394-403.
26. Fu J, Huang H, Liu J, Pi R, Chen J, et al. (2007) Tanshinone IIA protects cardiac myocytes against oxidative stress-triggered damage and apoptosis. Eur J Pharmacol 568: 213-221.
27. Jin UH, Suh SJ, Chang HW, Son JK, Lee SH, et al. (2008) Tanshinone IIA from Salvia miltiorrhiza BUNGE inhibits human aortic smooth muscle cell migration and MMP-9 activity through AKT signaling pathway. J Cell Biochem 104: 15-26.
28. Won SH, Lee HJ, Jeong SJ, Lu J, Kim SH, (2012) Activation of p53 Signaling and Inhibition of Androgen Receptor Mediate Tanshinone IIA Induced G1 Arrest in LNCaP Prostate Cancer Cells. Phytother Res 26: 669-674.
29. Dai ZK, Qin JK, Huang JE, Luo Y, Xu Q, et al. (2012) Tanshinone IIA activates calcium-dependent apoptosis signaling pathway in human hepatoma cells. J Nat Med 66: 192-201.
30. Li X, Du JR, Bai B, Yu Y, Zheng XY, et al. (2008) [Inhibitory effects and mechanism of tanshinone IIA on proliferation of rat aortic smooth muscle cells]. Zhongguo Zhong Yao Za Zhi 33: 2146-2150.
31. Akyurek LM, Boehm M, Olive M, Zhou AX, San H, et al. (2010) Deficiency of cyclin-dependent kinase inhibitors p21Cip1 and p27Kip1 accelerates atherogenesis in apolipoprotein E-deficient mice. Biochem Biophys Res Commun 396: 359-363.
32. Tanner FC, Boehm M, Akyurek LM, San H, Yang ZY, et al. (2000) Differential effects of the cyclin-dependent kinase inhibitors p27(Kip1), p21(Cip1), and p16(Ink4) on vascular smooth muscle cell proliferation. Circulation 101: 2022-2025.
33. Hengst L, Reed SI, (1996) Translational control of p27Kip1 accumulation during the cell cycle. Science 271: 1861-1864.
34. Kotoshiba S, Nakayama K, (2005) [The degradation of p27 and cancer]. Nihon Rinsho 63: 2047-2056.
35. Tsvetkov LM, Yeh KH, Lee SJ, Sun H, Zhang H, (1999) p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27. Curr Biol 9: 661-664.
36. Ungermannova D, Gao Y, Liu X, (2005) Ubiquitination of p27Kip1 requires physical interaction with cyclin E and probable phosphate recognition by SKP2. J Biol Chem 280: 30301-30309.
37. Miyamoto T, Horiuchi A, Kashima H, Suzuki A, Yamada T, et al. (2010) Inverse correlation between Skp2 and p27(Kip1) in normal endometrium and endometrial carcinoma. Gynecol Endocrinol 26: 220-229.
38. Hu L, Ibrahim S, Liu C, Skaar J, Pagano M, et al. (2009) Thrombin induces tumor cell cycle activation and spontaneous growth by down-regulation of p27Kip1, in association with the up-regulation of Skp2 and MiR-222. Cancer Res 69: 3374-3381.
39. Wu YJ, Sala-Newby GB, Shu KT, Yeh HI, Nakayama KI, et al. (2009) S-phase kinase-associated protein-2 (Skp2) promotes vascular smooth muscle cell proliferation and neointima formation in vivo. J Vasc Surg 50: 1135-1142.
40. Lin HK, Wang G, Chen Z, Teruya-Feldstein J, Liu Y, et al. (2009) Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB. Nat Cell Biol 11: 420-432.
41. Auld CA, Hopkins RG, Fernandes KM, Morrison RF, (2006) Novel effect of helenalin on Akt signaling and Skp2 expression in 3T3-L1 preadipocytes. Biochem Biophys Res Commun 346: 314-320.
42. Liu W, Asa SL, Fantus IG, Walfish PG, Ezzat S, (2002) Vitamin D arrests thyroid carcinoma cell growth and induces p27 dephosphorylation and accumulation through PTEN/akt-dependent and-independent pathways. Am J Pathol 160: 511-519.
43. Chu IM, Hengst L, Slingerland JM, (2008) The Cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapy. Nat Rev Cancer 8: 253-267.
44. Yi B, Qian GS, Bai L, (2008) [The changes of PTEN/Akt1 expression and cell proliferation in pulmonary arterial smooth muscle cells induced by hypoxia in rats]. Zhonghua Jie He He Hu Xi Za Zhi 31: 586-590.