-
1
-
-
0023633015
-
Reactive microglia in patients with senile dementia of the Alzheimer type are positive for the histocompatibility glycoprotein HLA-DR
-
P.L. McGeer, S. Itagaki, H. Tago, and E.G. McGeer Reactive microglia in patients with senile dementia of the Alzheimer type are positive for the histocompatibility glycoprotein HLA-DR Neurosci Lett 79 1987 195 200 (Pubitemid 17144469)
-
(1987)
Neuroscience Letters
, vol.79
, Issue.1-2
, pp. 195-200
-
-
McGeer, P.L.1
Itagaki, S.2
Tago, H.3
McGeer, E.G.4
-
2
-
-
0024157709
-
Expression of immune system-associated antigens by cells of the human central nervous system: Relationship to the pathology of Alzheimer's disease
-
J. Rogers, J. Luber-Narod, S.D. Styren, and W.H. Civin Expression of immune system-associated antigens by cells of the human central nervous system: relationship to the pathology of Alzheimer's disease Neurobiol Aging 9 1988 339 349 (Pubitemid 19262065)
-
(1988)
Neurobiology of Aging
, vol.9
, Issue.4
, pp. 339-349
-
-
Rogers, J.1
Luber-Narod, J.2
Styren, S.D.3
Civin, W.H.4
-
3
-
-
0023772808
-
Presence of T-cytotoxic suppressor and leucocyte common antigen positive cells in Alzheimer's disease brain tissue
-
S. Itagaki, P.L. McGeer, and H. Akiyama Presence of T-cytotoxic suppressor and leucocyte common antigen positive cells in Alzheimer's disease brain tissue Neurosci Lett 91 1988 259 264
-
(1988)
Neurosci Lett
, vol.91
, pp. 259-264
-
-
Itagaki, S.1
McGeer, P.L.2
Akiyama, H.3
-
4
-
-
0024543574
-
Complement activation in amyloid plaques in Alzheimer's dementia
-
P. Eikelenboom, C.E. Hack, J.M. Rozemuller, and F.C. Stam Complement activation in amyloid plaques in Alzheimer's dementia Virchows Arch B Cell Pathol Incl Mol Pathol 56 1989 259 262 (Pubitemid 19049180)
-
(1989)
Virchows Archiv Abteilung B Cell Pathology
, vol.56
, Issue.4
, pp. 259-262
-
-
Eikelenboom, P.1
Hack, C.E.2
Rozemuller, J.M.3
Stam, F.C.4
-
5
-
-
84865199264
-
Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: A microarray study
-
D.H. Cribbs, N.C. Berchtold, V. Perreau, P.D. Coleman, J. Rogers, and A.J. Tenner et al. Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study J Neuroinflammation 9 2012 179
-
(2012)
J Neuroinflammation
, vol.9
, pp. 179
-
-
Cribbs, D.H.1
Berchtold, N.C.2
Perreau, V.3
Coleman, P.D.4
Rogers, J.5
Tenner, A.J.6
-
7
-
-
67649653963
-
Age-associated increase in cytokine production during systemic inflammation: Adipose tissue as a major source of IL-6
-
M.E. Starr, B.M. Evers, and H. Saito Age-associated increase in cytokine production during systemic inflammation: adipose tissue as a major source of IL-6 J Gerontol A Biol Sci Med Sci 64 2009 723 730
-
(2009)
J Gerontol A Biol Sci Med Sci
, vol.64
, pp. 723-730
-
-
Starr, M.E.1
Evers, B.M.2
Saito, H.3
-
8
-
-
0036569812
-
Inhibition of COX-2 reduces the age-dependent increase of hippocampal inflammatory markers, corticosterone secretion, and behavioral impairments in the rat
-
DOI 10.1002/jnr.10192
-
P. Casolini, A. Catalani, A.R. Zuena, and L. Angelucci Inhibition of COX-2 reduces the age-dependent increase of hippocampal inflammatory markers, corticosterone secretion, and behavioral impairments in the rat J Neurosci Res 68 2002 337 343 (Pubitemid 34462539)
-
(2002)
Journal of Neuroscience Research
, vol.68
, Issue.3
, pp. 337-343
-
-
Casolini, P.1
Catalani, A.2
Zuena, A.R.3
Angelucci, L.4
-
9
-
-
79960068090
-
Cognitive dysfunction with aging and the role of inflammation
-
A.A. Simen, K.A. Bordner, M.P. Martin, L.A. Moy, and L.C. Barry Cognitive dysfunction with aging and the role of inflammation Ther Adv Chronic Dis 2 2011 175 195
-
(2011)
Ther Adv Chronic Dis
, vol.2
, pp. 175-195
-
-
Simen, A.A.1
Bordner, K.A.2
Martin, M.P.3
Moy, L.A.4
Barry, L.C.5
-
10
-
-
70349570588
-
Systemic inflammation and disease progression in Alzheimer disease
-
C. Holmes, C. Cunningham, E. Zotova, J. Woolford, C. Dean, and S. Kerr et al. Systemic inflammation and disease progression in Alzheimer disease Neurology 73 2009 768 774
-
(2009)
Neurology
, vol.73
, pp. 768-774
-
-
Holmes, C.1
Cunningham, C.2
Zotova, E.3
Woolford, J.4
Dean, C.5
Kerr, S.6
-
11
-
-
74949100134
-
Association of C-reactive protein with cognitive impairment
-
J.M. Noble, J.J. Manly, N. Schupf, M.X. Tang, R. Mayeux, and J.A. Luchsinger Association of C-reactive protein with cognitive impairment Arch Neurol 67 2010 87 92
-
(2010)
Arch Neurol
, vol.67
, pp. 87-92
-
-
Noble, J.M.1
Manly, J.J.2
Schupf, N.3
Tang, M.X.4
Mayeux, R.5
Luchsinger, J.A.6
-
12
-
-
84866062627
-
Gene expression profiling in human neurodegenerative disease
-
J. Cooper-Knock, J. Kirby, L. Ferraiuolo, P.R. Heath, M. Rattray, and P.J. Shaw Gene expression profiling in human neurodegenerative disease Nat Rev Neurol 8 2012 518 530
-
(2012)
Nat Rev Neurol
, vol.8
, pp. 518-530
-
-
Cooper-Knock, J.1
Kirby, J.2
Ferraiuolo, L.3
Heath, P.R.4
Rattray, M.5
Shaw, P.J.6
-
13
-
-
84875655895
-
Inflammation in Alzheimer disease-A brief review of the basic science and clinical literature
-
T. Wyss-Coray, and J. Rogers Inflammation in Alzheimer disease-a brief review of the basic science and clinical literature Cold Spring Harb Perspect Med 2 2012 a006346
-
(2012)
Cold Spring Harb Perspect Med
, vol.2
, pp. 006346
-
-
Wyss-Coray, T.1
Rogers, J.2
-
14
-
-
84896985687
-
Proinflammatory cytokines, aging, and age-related diseases
-
M. Michaud, L. Balardy, G. Moulis, C. Gaudin, C. Peyrot, and B. Vellas et al. Proinflammatory cytokines, aging, and age-related diseases J Am Med Dir Assoc 2013
-
(2013)
J Am Med Dir Assoc
-
-
Michaud, M.1
Balardy, L.2
Moulis, G.3
Gaudin, C.4
Peyrot, C.5
Vellas, B.6
-
15
-
-
77949892665
-
Non-steroidal anti-inflammatory drugs and Alzheimer's disease: The epidemiological evidence
-
C.A. Szekely, and P.P. Zandi Non-steroidal anti-inflammatory drugs and Alzheimer's disease: the epidemiological evidence CNS Neurol Disord Drug Targets 9 2010 132 139
-
(2010)
CNS Neurol Disord Drug Targets
, vol.9
, pp. 132-139
-
-
Szekely, C.A.1
Zandi, P.P.2
-
17
-
-
0024317005
-
Activation of the classical complement pathway in brain tissue of Alzheimer patients
-
DOI 10.1016/0304-3940(89)90843-4
-
P.L. McGeer, H. Akiyama, S. Itagaki, and E.G. McGeer Activation of the classical complement pathway in brain tissue of Alzheimer patients Neurosci Lett 107 1989 341 346 (Pubitemid 20013261)
-
(1989)
Neuroscience Letters
, vol.107
, Issue.1-3
, pp. 341-346
-
-
McGeer, P.L.1
Akiyama, H.2
Itagaki, S.3
McGeer, E.G.4
-
18
-
-
0025332027
-
Anti-inflammatory drugs and Alzheimer disease
-
P.L. McGeer, E. McGeer, J. Rogers, and J. Sibley Anti-inflammatory drugs and Alzheimer disease Lancet 335 1990 1037 (Pubitemid 20148621)
-
(1990)
Lancet
, vol.335
, Issue.8696
, pp. 1037
-
-
McGeer, P.L.1
McGeer, E.2
Rogers, J.3
Sibley, J.4
-
19
-
-
0025851789
-
Rheumatoid arthritis and susceptibility to Alzheimer's disease
-
C.M. Beard, E. Kokman, and L.T. Kurland Rheumatoid arthritis and susceptibility to Alzheimer's disease Lancet 337 1991 1426
-
(1991)
Lancet
, vol.337
, pp. 1426
-
-
Beard, C.M.1
Kokman, E.2
Kurland, L.T.3
-
20
-
-
0027268393
-
Clinical trial of indomethacin in Alzheimer's disease
-
J. Rogers, L.C. Kirby, S.R. Hempelman, D.L. Berry, P.L. McGeer, and A.W. Kaszniak et al. Clinical trial of indomethacin in Alzheimer's disease Neurology 43 1993 1609 1611 (Pubitemid 23230557)
-
(1993)
Neurology
, vol.43
, Issue.8
, pp. 1609-1611
-
-
Rogers, J.1
Kirby, L.C.2
Hempelman, S.R.3
Berry, D.L.4
McGeer, P.L.5
Kaszniak, A.W.6
Zalinski, J.7
Cofield, M.8
Mansukhani, L.9
Willson, P.10
Kogan, F.11
-
21
-
-
0028289083
-
Inverse association of anti-inflammatory treatments and Alzheimer's disease: Initial results of a co-twin control study
-
J.C. Breitner, B.A. Gau, K.A. Welsh, B.L. Plassman, W.M. McDonald, and M.J. Helms et al. Inverse association of anti-inflammatory treatments and Alzheimer's disease: initial results of a co-twin control study Neurology 44 1994 227 232 (Pubitemid 24070956)
-
(1994)
Neurology
, vol.44
, Issue.2
, pp. 227-232
-
-
Breitner, J.C.S.1
Gau, B.A.2
Welsh, K.A.3
Plassman, B.L.4
McDonald, W.M.5
Helms, M.J.6
Anthony, J.C.7
-
22
-
-
0028896679
-
Nonsteroidal anti-inflammatory drugs in Alzheimer's disease
-
J.B. Rich, D.X. Rasmusson, M.F. Folstein, K.A. Carson, C. Kawas, and J. Brandt Nonsteroidal anti-inflammatory drugs in Alzheimer's disease Neurology 45 1995 51 55
-
(1995)
Neurology
, vol.45
, pp. 51-55
-
-
Rich, J.B.1
Rasmusson, D.X.2
Folstein, M.F.3
Carson, K.A.4
Kawas, C.5
Brandt, J.6
-
23
-
-
0030897133
-
Risk of Alzheimer's disease and duration of NSAID use
-
W.F. Stewart, C. Kawas, M. Corrada, and E.J. Metter Risk of Alzheimer's disease and duration of NSAID use Neurology 48 1997 626 632 (Pubitemid 27120096)
-
(1997)
Neurology
, vol.48
, Issue.3
, pp. 626-632
-
-
Stewart, W.F.1
Kawas, C.2
Corrada, M.3
Metter, E.J.4
-
24
-
-
0028080315
-
The Canadian Study of Health and Aging: Risk factors for Alzheimer's disease in Canada
-
I. Mcdowell, G. Hill, and J. Lindsay et al. The Canadian Study of Health and Aging: risk factors for Alzheimer's disease in Canada Neurology 44 1994 2073 2080 (Pubitemid 24349508)
-
(1994)
Neurology
, vol.44
, Issue.11
, pp. 2073-2080
-
-
Lindsay, J.1
-
25
-
-
0031686954
-
Nonsteroidal anti-inflammatory drug use and Alzheimer's disease: A case-control study in Rochester, Minnesota, 1980 through 1984
-
C.M. Beard, S.C. Waring, P.C. O'Brien, L.T. Kurland, and E. Kokmen Nonsteroidal anti-inflammatory drug use and Alzheimer's disease: a case-control study in Rochester, Minnesota, 1980 through 1984 Mayo Clin Proc 73 1998 951 955
-
(1998)
Mayo Clin Proc
, vol.73
, pp. 951-955
-
-
Beard, C.M.1
Waring, S.C.2
O'Brien, P.C.3
Kurland, L.T.4
Kokmen, E.5
-
26
-
-
77952544355
-
Anti-inflammatory treatment in AD mice protects against neuronal pathology
-
J.K. Choi, B.G. Jenkins, I. Carreras, S. Kaymakcalan, K. Cormier, and N.W. Kowall et al. Anti-inflammatory treatment in AD mice protects against neuronal pathology Exp Neurol 223 2010 377 384
-
(2010)
Exp Neurol
, vol.223
, pp. 377-384
-
-
Choi, J.K.1
Jenkins, B.G.2
Carreras, I.3
Kaymakcalan, S.4
Cormier, K.5
Kowall, N.W.6
-
27
-
-
72849109858
-
NSAIDs prevent, but do not reverse, neuronal cell cycle reentry in a mouse model of Alzheimer disease
-
N.H. Varvel, K. Bhaskar, M.Z. Kounnas, S.L. Wagner, Y. Yang, and B.T. Lamb et al. NSAIDs prevent, but do not reverse, neuronal cell cycle reentry in a mouse model of Alzheimer disease J Clin Invest 119 2009 3692 3702
-
(2009)
J Clin Invest
, vol.119
, pp. 3692-3702
-
-
Varvel, N.H.1
Bhaskar, K.2
Kounnas, M.Z.3
Wagner, S.L.4
Yang, Y.5
Lamb, B.T.6
-
28
-
-
9644275598
-
Modulation of nuclear factor-κB activity by indomethacin influences Aβ levels but not Aβ precursor protein metabolism in a model of Alzheimer's disease
-
S. Sung, H. Yang, K. Uryu, E.B. Lee, L. Zhao, and D. Shineman et al. Modulation of nuclear factor-kappa B activity by indomethacin influences A beta levels but not A beta precursor protein metabolism in a model of Alzheimer's disease Am J Pathol 165 2004 2197 2206 (Pubitemid 39578396)
-
(2004)
American Journal of Pathology
, vol.165
, Issue.6
, pp. 2197-2206
-
-
Sung, S.1
Yang, H.2
Uryu, K.3
Lee, E.B.4
Zhao, L.5
Shineman, D.6
Trojanowski, J.Q.7
Lee, V.M.-Y.8
Pratico, D.9
-
29
-
-
0034254924
-
Ibuprofen suppresses plaque pathology and inflammation in a mouse model for alzheimer's disease
-
G.P. Lim, F. Yang, T. Chu, P. Chen, W. Beech, and B. Teter et al. Ibuprofen suppresses plaque pathology and inflammation in a mouse model for Alzheimer's disease J Neurosci 20 2000 5709 5714 (Pubitemid 30636898)
-
(2000)
Journal of Neuroscience
, vol.20
, Issue.15
, pp. 5709-5714
-
-
Lim, G.P.1
Yang, F.2
Chu, T.3
Chen, P.4
Beech, W.5
Teter, B.6
Tran, T.7
Ubeda, O.8
Ashe, K.H.9
Frautschy, S.A.10
Cole, G.M.11
-
30
-
-
0035691115
-
Ibuprofen effects on Alzheimer pathology and open field activity in APPsw transgenic mice
-
DOI 10.1016/S0197-4580(01)00299-8, PII S0197458001002998
-
G.P. Lim, F. Yang, T. Chu, E. Gahtan, O. Ubeda, and W. Beech et al. Ibuprofen effects on Alzheimer pathology and open field activity in APPsw transgenic mice Neurobiol Aging 22 2001 983 991 (Pubitemid 34066567)
-
(2001)
Neurobiology of Aging
, vol.22
, Issue.6
, pp. 983-991
-
-
Lim, G.P.1
Yang, F.2
Chu, T.3
Gahtan, E.4
Ubeda, O.5
Beech, W.6
Overmier, J.B.7
Hsiao-Ashec, K.8
Frautschy, S.A.9
Cole, G.M.10
-
31
-
-
41949119161
-
Ibuprofen reduces Abeta, hyperphosphorylated tau and memory deficits in Alzheimer mice
-
A.C. McKee, I. Carreras, L. Hossain, H. Ryu, W.L. Klein, and S. Oddo et al. Ibuprofen reduces Abeta, hyperphosphorylated tau and memory deficits in Alzheimer mice Brain Res 1207 2008 225 236
-
(2008)
Brain Res
, vol.1207
, pp. 225-236
-
-
McKee, A.C.1
Carreras, I.2
Hossain, L.3
Ryu, H.4
Klein, W.L.5
Oddo, S.6
-
32
-
-
84870946801
-
Cyclooxygenase-1 inhibition reduces amyloid pathology and improves memory deficits in a mouse model of Alzheimer's disease
-
S.H. Choi, S. Aid, L. Caracciolo, S.S. Minami, T. Niikura, and Y. Matsuoka et al. Cyclooxygenase-1 inhibition reduces amyloid pathology and improves memory deficits in a mouse model of Alzheimer's disease J Neurochem 124 2013 59 68
-
(2013)
J Neurochem
, vol.124
, pp. 59-68
-
-
Choi, S.H.1
Aid, S.2
Caracciolo, L.3
Minami, S.S.4
Niikura, T.5
Matsuoka, Y.6
-
33
-
-
34249058674
-
Naproxen and celecoxib do not prevent AD in early results from a randomized controlled trial
-
DOI 10.1212/01.wnl.0000260269.93245.d2
-
C.G. Lyketsos, J.C. Breitner, R.C. Green, B.K. Martin, C. Meinert, and S. Piantadosi et al. Naproxen and celecoxib do not prevent AD in early results from a randomized controlled trial Neurology 68 2007 1800 1808 (Pubitemid 46791392)
-
(2007)
Neurology
, vol.68
, Issue.21
, pp. 1800-1808
-
-
Lyketsos, C.G.1
Breitner, J.C.S.2
Green, R.C.3
Martin, B.K.4
Meinert, C.5
Piantadosi, S.6
Sabbagh, M.7
-
34
-
-
47549107705
-
Cognitive function over time in the Alzheimer's disease anti-inflammatory prevention trial (ADAPT): Results of a randomized, controlled trial of naproxen and celecoxib
-
DOI 10.1001/archneur.2008.65.7.nct70006
-
B.K. Martin, C. Szekely, J. Brandt, S. Piantadosi, J.C. Breitner, and S. Craft et al. Cognitive function over time in the Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT): results of a randomized, controlled trial of naproxen and celecoxib Arch Neurol 65 2008 896 905 (Pubitemid 352008472)
-
(2008)
Archives of Neurology
, vol.65
, Issue.7
, pp. 896-905
-
-
Martin, B.K.1
Szekely, C.2
Brandt, J.3
Piantadosi, S.4
Breitner, J.C.S.5
Craft, S.6
Evans, D.7
Green, R.8
Mullan, M.9
-
35
-
-
41049113596
-
The suspension of treatments in ADAPT: Concerns beyond the cardiovascular safety of celecoxib or naproxen
-
J.C. Breitner, B.K. Martin, and C.L. Meinert The suspension of treatments in ADAPT: concerns beyond the cardiovascular safety of celecoxib or naproxen PLoS Clin Trials 1 2006 e41
-
(2006)
PLoS Clin Trials
, vol.1
, pp. 41
-
-
Breitner, J.C.1
Martin, B.K.2
Meinert, C.L.3
-
36
-
-
80053383308
-
Effects of non-steroidal anti-inflammatory drug treatments on cognitive decline vary by phase of pre-clinical Alzheimer disease: Findings from the randomized controlled Alzheimer's disease anti-inflammatory prevention trial
-
J.M. Leoutsakos, B.O. Muthen, J.C. Breitner, and C.G. Lyketsos Effects of non-steroidal anti-inflammatory drug treatments on cognitive decline vary by phase of pre-clinical Alzheimer disease: findings from the randomized controlled Alzheimer's disease anti-inflammatory prevention trial Int J Geriatr Psychiatry 27 2012 364 374
-
(2012)
Int J Geriatr Psychiatry
, vol.27
, pp. 364-374
-
-
Leoutsakos, J.M.1
Muthen, B.O.2
Breitner, J.C.3
Lyketsos, C.G.4
-
37
-
-
79960769591
-
Extended results of the Alzheimer's disease anti-inflammatory prevention trial
-
J.C. Breitner, L.D. Baker, T.J. Montine, C.L. Meinert, C.G. Lyketsos, and K.H. Ashe et al. Extended results of the Alzheimer's disease anti-inflammatory prevention trial Alzheimers Dement 7 2011 402 411
-
(2011)
Alzheimers Dement
, vol.7
, pp. 402-411
-
-
Breitner, J.C.1
Baker, L.D.2
Montine, T.J.3
Meinert, C.L.4
Lyketsos, C.G.5
Ashe, K.H.6
-
38
-
-
77955278262
-
'Too much good news' - Are Alzheimer mouse models trying to tell us how to prevent, not cure, Alzheimer's disease?
-
K.R. Zahs, and K.H. Ashe 'Too much good news' - are Alzheimer mouse models trying to tell us how to prevent, not cure, Alzheimer's disease? Trends Neurosci 33 2010 381 389
-
(2010)
Trends Neurosci
, vol.33
, pp. 381-389
-
-
Zahs, K.R.1
Ashe, K.H.2
-
39
-
-
80053307147
-
Cardiovascular risk with non-steroidal anti-inflammatory drugs: Systematic review of population-based controlled observational studies
-
P. McGettigan, and D. Henry Cardiovascular risk with non-steroidal anti-inflammatory drugs: systematic review of population-based controlled observational studies PLoS Med 8 2011 e1001098
-
(2011)
PLoS Med
, vol.8
, pp. 1001098
-
-
McGettigan, P.1
Henry, D.2
-
40
-
-
84887006586
-
A vasoconstrictor role for cyclooxygenase-1-mediated prostacyclin synthesis in mouse renal arteries
-
B. Liu, Y. Zhang, N. Zhu, H. Li, W. Luo, and Y. Zhou A vasoconstrictor role for cyclooxygenase-1-mediated prostacyclin synthesis in mouse renal arteries Am J Physiol Renal Physiol 2013
-
(2013)
Am J Physiol Renal Physiol
-
-
Liu, B.1
Zhang, Y.2
Zhu, N.3
Li, H.4
Luo, W.5
Zhou, Y.6
-
41
-
-
84879062991
-
Synthesis, pharmacological characterization, and docking analysis of a novel family of diarylisoxazoles as highly selective cyclooxygenase-1 (COX-1) inhibitors
-
P. Vitale, S. Tacconelli, M.G. Perrone, P. Malerba, L. Simone, and A. Scilimati et al. Synthesis, pharmacological characterization, and docking analysis of a novel family of diarylisoxazoles as highly selective cyclooxygenase-1 (COX-1) inhibitors J Med Chem 56 2013 4277 4299
-
(2013)
J Med Chem
, vol.56
, pp. 4277-4299
-
-
Vitale, P.1
Tacconelli, S.2
Perrone, M.G.3
Malerba, P.4
Simone, L.5
Scilimati, A.6
-
42
-
-
84873412628
-
Impact of the prostaglandin synthase-2 inhibitor celecoxib on ovulation and luteal events in women
-
A.B. Edelman, J.T. Jensen, C. Doom, and J.D. Hennebold Impact of the prostaglandin synthase-2 inhibitor celecoxib on ovulation and luteal events in women Contraception 87 2013 352 357
-
(2013)
Contraception
, vol.87
, pp. 352-357
-
-
Edelman, A.B.1
Jensen, J.T.2
Doom, C.3
Hennebold, J.D.4
-
43
-
-
84898750450
-
Titrated oral misoprostol for augmenting labour to improve maternal and neonatal outcomes
-
J.P. Vogel, H.M. West, and T. Dowswell Titrated oral misoprostol for augmenting labour to improve maternal and neonatal outcomes Cochrane Database Syst Rev 9 2013 CD010648
-
(2013)
Cochrane Database Syst Rev
, vol.9
, pp. 010648
-
-
Vogel, J.P.1
West, H.M.2
Dowswell, T.3
-
44
-
-
84875463275
-
LGR5 promotes survival in human colorectal adenoma cells and is upregulated by PGE2: Implications for targeting adenoma stem cells with NSAIDs
-
M.R. Al-Kharusi, H.J. Smartt, A. Greenhough, T.J. Collard, E.D. Emery, and A.C. Williams et al. LGR5 promotes survival in human colorectal adenoma cells and is upregulated by PGE2: implications for targeting adenoma stem cells with NSAIDs Carcinogenesis 34 2013 1150 1157
-
(2013)
Carcinogenesis
, vol.34
, pp. 1150-1157
-
-
Al-Kharusi, M.R.1
Smartt, H.J.2
Greenhough, A.3
Collard, T.J.4
Emery, E.D.5
Williams, A.C.6
-
45
-
-
84871155102
-
Antitumor activity of the selective cyclooxygenase-2 inhibitor, celecoxib, on breast cancer in vitro and in vivo
-
Z.J. Dai, X.B. Ma, H.F. Kang, J. Gao, W.L. Min, and H.T. Guan et al. Antitumor activity of the selective cyclooxygenase-2 inhibitor, celecoxib, on breast cancer in vitro and in vivo Cancer Cell Int 12 2012 53
-
(2012)
Cancer Cell Int
, vol.12
, pp. 53
-
-
Dai, Z.J.1
Ma, X.B.2
Kang, H.F.3
Gao, J.4
Min, W.L.5
Guan, H.T.6
-
46
-
-
84871955193
-
Inflammatory prostaglandin E2 signaling in a mouse model of Alzheimer disease
-
J. Shi, Q. Wang, J.U. Johansson, X. Liang, N.S. Woodling, and P. Priyam et al. Inflammatory prostaglandin E2 signaling in a mouse model of Alzheimer disease Ann Neurol 72 2012 788 798
-
(2012)
Ann Neurol
, vol.72
, pp. 788-798
-
-
Shi, J.1
Wang, Q.2
Johansson, J.U.3
Liang, X.4
Woodling, N.S.5
Priyam, P.6
-
47
-
-
84859511924
-
Critical role of cPLA2 in Abeta oligomer-induced neurodegeneration and memory deficit
-
e17-29
-
C. Desbene, C. Malaplate-Armand, I. Youssef, P. Garcia, C. Stenger, and M. Sauvee et al. Critical role of cPLA2 in Abeta oligomer-induced neurodegeneration and memory deficit Neurobiol Aging 33 2012 1123 e17-29
-
(2012)
Neurobiol Aging
, vol.33
, pp. 1123
-
-
Desbene, C.1
Malaplate-Armand, C.2
Youssef, I.3
Garcia, P.4
Stenger, C.5
Sauvee, M.6
-
48
-
-
84885440280
-
Cytosolic phospholipase Aalpha upregulation mediates apoptotic neuronal death induced by aggregated amyloid-beta peptide
-
C. Sagy-Bross, N. Hadad, and R. Levy Cytosolic phospholipase Aalpha upregulation mediates apoptotic neuronal death induced by aggregated amyloid-beta peptide Neurochem Int 63 2013 541 550
-
(2013)
Neurochem Int
, vol.63
, pp. 541-550
-
-
Sagy-Bross, C.1
Hadad, N.2
Levy, R.3
-
49
-
-
0037237777
-
2 knockout mouse
-
DOI 10.1194/jlr.M200298-JLR200
-
T.A. Rosenberger, N.E. Villacreses, M.A. Contreras, J.V. Bonventre, and S.I. Rapoport Brain lipid metabolism in the cPLA2 knockout mouse J Lipid Res 44 2003 109 117 (Pubitemid 36114776)
-
(2003)
Journal of Lipid Research
, vol.44
, Issue.1
, pp. 109-117
-
-
Rosenberger, T.A.1
Villacreses, N.E.2
Contreras, M.A.3
Bonventre, J.V.4
Rapoport, S.I.5
-
50
-
-
84868095954
-
The diacylglycerol lipases: Structure, regulation and roles in and beyond endocannabinoid signalling
-
M. Reisenberg, P.K. Singh, G. Williams, and P. Doherty The diacylglycerol lipases: structure, regulation and roles in and beyond endocannabinoid signalling Philos Trans R Soc Lond B Biol Sci 367 2012 3264 3275
-
(2012)
Philos Trans R Soc Lond B Biol Sci
, vol.367
, pp. 3264-3275
-
-
Reisenberg, M.1
Singh, P.K.2
Williams, G.3
Doherty, P.4
-
51
-
-
81055156684
-
Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation
-
D.K. Nomura, B.E. Morrison, J.L. Blankman, J.Z. Long, S.G. Kinsey, and M.C. Marcondes et al. Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation Science 334 2011 809 813
-
(2011)
Science
, vol.334
, pp. 809-813
-
-
Nomura, D.K.1
Morrison, B.E.2
Blankman, J.L.3
Long, J.Z.4
Kinsey, S.G.5
Marcondes, M.C.6
-
53
-
-
77952970098
-
Cyclooxygenase-2 controls energy homeostasis in mice by de novo recruitment of brown adipocytes
-
A. Vegiopoulos, K. Muller-Decker, D. Strzoda, I. Schmitt, E. Chichelnitskiy, and A. Ostertag et al. Cyclooxygenase-2 controls energy homeostasis in mice by de novo recruitment of brown adipocytes Science 328 2010 1158 1161
-
(2010)
Science
, vol.328
, pp. 1158-1161
-
-
Vegiopoulos, A.1
Muller-Decker, K.2
Strzoda, D.3
Schmitt, I.4
Chichelnitskiy, E.5
Ostertag, A.6
-
54
-
-
0028818913
-
Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II
-
J.E. Dinchuk, B.D. Car, R.J. Focht, J.J. Johnston, B.D. Jaffee, and M.B. Covington et al. Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II Nature 378 1995 406 409
-
(1995)
Nature
, vol.378
, pp. 406-409
-
-
Dinchuk, J.E.1
Car, B.D.2
Focht, R.J.3
Johnston, J.J.4
Jaffee, B.D.5
Covington, M.B.6
-
55
-
-
0030702122
-
Multiple female reproductive failures in cyclooxygenase 2-deficient mice
-
DOI 10.1016/S0092-8674(00)80402-X
-
H. Lim, B.C. Paria, S.K. Das, J.E. Dinchuk, R. Langenbach, and J.M. Trzaskos et al. Multiple female reproductive failures in cyclooxygenase 2-deficient mice Cell 91 1997 197 208 (Pubitemid 27456387)
-
(1997)
Cell
, vol.91
, Issue.2
, pp. 197-208
-
-
Lim, H.1
Paria, B.C.2
Das, S.K.3
Dinchuk, J.E.4
Langenbach, R.5
Trzaskos, J.M.6
Dey, S.K.7
-
56
-
-
19744380776
-
Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial
-
DOI 10.1056/NEJMoa050493
-
R.S. Bresalier, R.S. Sandler, H. Quan, J.A. Bolognese, B. Oxenius, and K. Horgan et al. Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial N Engl J Med 352 2005 1092 1102 (Pubitemid 40365350)
-
(2005)
New England Journal of Medicine
, vol.352
, Issue.11
, pp. 1092-1102
-
-
Bresalier, R.S.1
Sandler, R.S.2
Quan, H.3
Bolognese, J.A.4
Oxenius, B.5
Horgan, K.6
Lines, C.7
Riddell, R.8
Morton, D.9
Lanas, A.10
Konstam, M.A.11
Baron, J.A.12
-
57
-
-
78751695197
-
Cardiovascular safety of non-steroidal anti-inflammatory drugs: Network meta-analysis
-
S. Trelle, S. Reichenbach, S. Wandel, P. Hildebrand, B. Tschannen, and P.M. Villiger et al. Cardiovascular safety of non-steroidal anti-inflammatory drugs: network meta-analysis BMJ 342 2011 c7086
-
(2011)
BMJ
, vol.342
, pp. 7086
-
-
Trelle, S.1
Reichenbach, S.2
Wandel, S.3
Hildebrand, P.4
Tschannen, B.5
Villiger, P.M.6
-
58
-
-
47249162481
-
Cyclooxygenase-1 and -2 in the different stages of Alzheimer's disease pathology
-
DOI 10.2174/138161208784480171
-
J.J. Hoozemans, J.M. Rozemuller, E.S. van Haastert, R. Veerhuis, and P. Eikelenboom Cyclooxygenase-1 and -2 in the different stages of Alzheimer's disease pathology Curr Pharm Des 14 2008 1419 1427 (Pubitemid 351982549)
-
(2008)
Current Pharmaceutical Design
, vol.14
, Issue.14
, pp. 1419-1427
-
-
Hoozemans, J.J.M.1
Rozemuller, J.M.2
Van Haastert, E.S.3
Veerhuis, R.4
Eikelenboom, P.5
-
59
-
-
0033608169
-
Increased expression of cyclooxygenases and peroxisome proliferator-activated receptor-γ in Alzheimer's disease brains
-
DOI 10.1006/bbrc.1998.9981
-
Y. Kitamura, S. Shimohama, H. Koike, J. Kakimura, Y. Matsuoka, and Y. Nomura et al. Increased expression of cyclooxygenases and peroxisome proliferator-activated receptor-gamma in Alzheimer's disease brains Biochem Biophys Res Commun 254 1999 582 586 (Pubitemid 29290509)
-
(1999)
Biochemical and Biophysical Research Communications
, vol.254
, Issue.3
, pp. 582-586
-
-
Kitamura, Y.1
Shimohama, S.2
Koike, H.3
Kakimura, J.-I.4
Matsuoka, Y.5
Nomura, Y.6
Gebicke-Haerter, P.J.7
Taniguchi, T.8
-
60
-
-
0037108979
-
COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: Cloning, structure, and expression
-
DOI 10.1073/pnas.162468699
-
N.V. Chandrasekharan, H. Dai, K.L. Roos, N.K. Evanson, J. Tomsik, and T.S. Elton et al. COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expression PNAS 99 2002 13926 13931 (Pubitemid 35215482)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.21
, pp. 13926-13931
-
-
Chandrasekharan, N.V.1
Dai, H.2
Roos, K.L.T.3
Evanson, N.K.4
Tomsik, J.5
Elton, T.S.6
Simmons, D.L.7
-
61
-
-
4043183388
-
Cyclooxygenase-3 gene expression in alzheimer hippocampus and in stressed human neural cells
-
DOI 10.1023/B:NERE.0000035809.70905.8a
-
J.G. Cui, H. Kuroda, N.V. Chandrasekharan, R.P. Pelaez, D.L. Simmons, and N.G. Bazan et al. Cyclooxygenase-3 gene expression in Alzheimer hippocampus and in stressed human neural cells Neurochem Res 29 2004 1731 1737 (Pubitemid 39070064)
-
(2004)
Neurochemical Research
, vol.29
, Issue.9
, pp. 1731-1737
-
-
Cui, J.-G.1
Kuroda, H.2
Chandrasekharan, N.V.3
Pelaez, R.P.4
Simmons, D.L.5
Bazan, N.G.6
Lukiw, W.J.7
-
62
-
-
84856519296
-
Differential role of cyclooxygenase isozymes on neuronal density in hippocampus CA1 region of intracerebroventricular streptozotocin treated rat brain
-
D.K. Dhull, D. Bhateja, R.K. Dhull, and S.S. Padi Differential role of cyclooxygenase isozymes on neuronal density in hippocampus CA1 region of intracerebroventricular streptozotocin treated rat brain J Chem Neuroanat 43 2012 48 51
-
(2012)
J Chem Neuroanat
, vol.43
, pp. 48-51
-
-
Dhull, D.K.1
Bhateja, D.2
Dhull, R.K.3
Padi, S.S.4
-
64
-
-
34248180111
-
2 is altered in rat hippocampus during normal aging
-
DOI 10.1016/j.brainresbull.2007.02.015, PII S0361923007000937
-
S. Aid, and F. Bosetti Gene expression of cyclooxygenase-1 and Ca(2+)-independent phospholipase A(2) is altered in rat hippocampus during normal aging Brain Res Bull 73 2007 108 113 (Pubitemid 46710255)
-
(2007)
Brain Research Bulletin
, vol.73
, Issue.1-3
, pp. 108-113
-
-
Aid, S.1
Bosetti, F.2
-
65
-
-
33746737072
-
2 and cyclooxygenase-2 in Rhesus monkey brain as a function of age
-
DOI 10.1016/j.brainresbull.2006.03.006, PII S036192300600089X
-
G.R. Weerasinghe, S.L. Coon, A.K. Bhattacharjee, G.J. Harry, and F. Bosetti Regional protein levels of cytosolic phospholipase A2 and cyclooxygenase-2 in Rhesus monkey brain as a function of age Brain Res Bull 69 2006 614 621 (Pubitemid 44250798)
-
(2006)
Brain Research Bulletin
, vol.69
, Issue.6
, pp. 614-621
-
-
Weerasinghe, G.R.1
Coon, S.L.2
Bhattacharjee, A.K.3
Harry, G.J.4
Bosetti, F.5
-
66
-
-
3142718813
-
Gene expression profiling in fetal, aged, and Alzheimer hippocampus: A continuum of stress-related signaling
-
DOI 10.1023/B:NERE.0000023615.89699.63
-
W.J. Lukiw Gene expression profiling in fetal, aged, and Alzheimer hippocampus: a continuum of stress-related signaling Neurochem Res 29 2004 1287 1297 (Pubitemid 39023501)
-
(2004)
Neurochemical Research
, vol.29
, Issue.6
, pp. 1287-1297
-
-
Lukiw, W.J.1
-
67
-
-
20444499367
-
Acute treatment with the PPARγ agonist pioglitazone and ibuprofen reduces glial inflammation and Aβ1-42 levels in APPV717I transgenic mice
-
DOI 10.1093/brain/awh452
-
M.T. Heneka, M. Sastre, L. Dumitrescu-Ozimek, A. Hanke, I. Dewachter, and C. Kuiperi et al. Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice Brain 128 2005 1442 1453 (Pubitemid 40826196)
-
(2005)
Brain
, vol.128
, Issue.6
, pp. 1442-1453
-
-
Heneka, M.T.1
Sastre, M.2
Dumitrescu-Ozimek, L.3
Hanke, A.4
Dewachter, I.5
Kuiperi, C.6
O'Banion, K.7
Klockgether, T.8
Van Leuven, F.9
Landreth, G.E.10
-
68
-
-
0037088914
-
Microglial activation and β-amyloid deposit reduction caused by a nitric oxide-releasing nonsteroidal anti-inflammatory drug in amyloid precursor protein plus presenilin-1 transgenic mice
-
P.T. Jantzen, K.E. Connor, G. DiCarlo, G.L. Wenk, J.L. Wallace, and A.M. Rojiani et al. Microglial activation and beta -amyloid deposit reduction caused by a nitric oxide-releasing nonsteroidal anti-inflammatory drug in amyloid precursor protein plus presenilin-1 transgenic mice J Neurosci 22 2002 2246 2254 (Pubitemid 35386524)
-
(2002)
Journal of Neuroscience
, vol.22
, Issue.6
, pp. 2246-2254
-
-
Jantzen, P.T.1
Connor, K.E.2
DiCarlo, G.3
Wenk, G.L.4
Wallace, J.L.5
Rojiani, A.M.6
Coppola, D.7
Morgan, D.8
Gordon, M.N.9
-
69
-
-
84870946801
-
Cyclooxygenase-1 inhibition reduces amyloid pathology and improves memory deficits in a mouse model of Alzheimer's disease
-
S.H. Choi, S. Aid, L. Caracciolo, S.S. Minami, T. Niikura, and Y. Matsuoka et al. Cyclooxygenase-1 inhibition reduces amyloid pathology and improves memory deficits in a mouse model of Alzheimer's disease J Neurochem 124 2012 59 68
-
(2012)
J Neurochem
, vol.124
, pp. 59-68
-
-
Choi, S.H.1
Aid, S.2
Caracciolo, L.3
Minami, S.S.4
Niikura, T.5
Matsuoka, Y.6
-
70
-
-
79951624773
-
Ibuprofen attenuates oxidative damage through NOX2 inhibition in Alzheimer's disease
-
e21-32
-
B.L. Wilkinson, P.E. Cramer, N.H. Varvel, E. Reed-Geaghan, Q. Jiang, and A. Szabo et al. Ibuprofen attenuates oxidative damage through NOX2 inhibition in Alzheimer's disease Neurobiol Aging 33 2010 197 e21-32
-
(2010)
Neurobiol Aging
, vol.33
, pp. 197
-
-
Wilkinson, B.L.1
Cramer, P.E.2
Varvel, N.H.3
Reed-Geaghan, E.4
Jiang, Q.5
Szabo, A.6
-
71
-
-
77953953898
-
Cyclooxygenase-1 null mice show reduced neuroinflammation in response to beta-amyloid
-
S.H. Choi, and F. Bosetti Cyclooxygenase-1 null mice show reduced neuroinflammation in response to beta-amyloid Aging (Albany, NY) 1 2009 234 244
-
(2009)
Aging (Albany, NY)
, vol.1
, pp. 234-244
-
-
Choi, S.H.1
Bosetti, F.2
-
72
-
-
77952545096
-
Triflusal reduces dense-core plaque load, associated axonal alterations and inflammatory changes, and rescues cognition in a transgenic mouse model of Alzheimer's disease
-
M. Coma, L. Sereno, B. Da Rocha-Souto, T.C. Scotton, J. Espana, and M.B. Sanchez et al. Triflusal reduces dense-core plaque load, associated axonal alterations and inflammatory changes, and rescues cognition in a transgenic mouse model of Alzheimer's disease Neurobiol Dis 38 2010 482 491
-
(2010)
Neurobiol Dis
, vol.38
, pp. 482-491
-
-
Coma, M.1
Sereno, L.2
Da Rocha-Souto, B.3
Scotton, T.C.4
Espana, J.5
Sanchez, M.B.6
-
73
-
-
21044458540
-
Diverse compounds mimic Alzheimer disease-causing mutations by augmenting Aβ42 production
-
DOI 10.1038/nm1235
-
T. Kukar, M.P. Murphy, J.L. Eriksen, S.A. Sagi, S. Weggen, and T.E. Smith et al. Diverse compounds mimic Alzheimer disease-causing mutations by augmenting Abeta42 production Nat Med 11 2005 545 550 (Pubitemid 40685978)
-
(2005)
Nature Medicine
, vol.11
, Issue.5
, pp. 545-550
-
-
Kukar, T.1
Murphy, M.P.2
Eriksen, J.L.3
Sagi, S.A.4
Weggen, S.5
Smith, T.E.6
Ladd, T.7
Khan, M.A.8
Kache, R.9
Beard, J.10
Dodson, M.11
Merit, S.12
Ozols, V.V.13
Anastasiadis, P.Z.14
Das, P.15
Fauq, A.16
Koo, E.H.17
Golde, T.E.18
-
74
-
-
0032725481
-
Cyclooxygenase-1 in human Alzheimer and control brain: Quantitative analysis of expression by microglia and CA3 hippocampal neurons
-
A.V. Yermakova, J. Rollins, L.M. Callahan, J. Rogers, and M.K. O'Banion Cyclooxygenase-1 in human Alzheimer and control brain: quantitative analysis of expression by microglia and CA3 hippocampal neurons J Neuropathol Exp Neurol 58 1999 1135 1146 (Pubitemid 29519837)
-
(1999)
Journal of Neuropathology and Experimental Neurology
, vol.58
, Issue.11
, pp. 1135-1146
-
-
Yermakova, A.V.1
Rollins, J.2
Callahan, L.M.3
Rogers, J.4
O'Banion, M.K.5
-
75
-
-
0035141118
-
Cyclooxygenase expression in microglia and neurons in Alzheimer's disease and control brain
-
J.J. Hoozemans, A.J. Rozemuller, I. Janssen, C.J. De Groot, R. Veerhuis, and P. Eikelenboom Cyclooxygenase expression in microglia and neurons in Alzheimer's disease and control brain Acta Neuropathol 101 2001 2 8 (Pubitemid 32124493)
-
(2001)
Acta Neuropathologica
, vol.101
, Issue.1
, pp. 2-8
-
-
Hoozemans, J.J.M.1
Rozemuller, A.J.M.2
Janssen, I.3
De Groot, C.J.A.4
Veerhuis, R.5
Eikelenboom, P.6
-
76
-
-
85047691727
-
NSAIDs and enantiomers of flurbiprofen target γ-secretase and lower Aβ42 in vivo
-
DOI 10.1172/JCI200318162
-
J.L. Eriksen, S.A. Sagi, T.E. Smith, S. Weggen, P. Das, and D.C. McLendon et al. NSAIDs and enantiomers of flurbiprofen target gamma-secretase and lower Abeta 42 in vivo J Clin Invest 112 2003 440 449 (Pubitemid 38063773)
-
(2003)
Journal of Clinical Investigation
, vol.112
, Issue.3
, pp. 440-449
-
-
Eriksen, J.L.1
Sagi, S.A.2
Smith, T.E.3
Weggen, S.4
Das, P.5
McLendon, D.C.6
Ozols, V.V.7
Jessing, K.W.8
Zavitz, K.H.9
Koo, E.H.10
Golde, T.E.11
-
77
-
-
0041876229
-
Evidence that nonsteroidal anti-inflammatory drugs decrease amyloid β42 production by direct modulation of γ-secretase activity
-
DOI 10.1074/jbc.M303592200
-
S. Weggen, J.L. Eriksen, S.A. Sagi, C.U. Pietrzik, V. Ozols, and A. Fauq et al. Evidence that nonsteroidal anti-inflammatory drugs decrease amyloid beta 42 production by direct modulation of gamma-secretase activity J Biol Chem 278 2003 31831 31837 (Pubitemid 37048365)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.34
, pp. 31831-31837
-
-
Weggen, S.1
Eriksen, J.L.2
Sagi, S.A.3
Pietrzik, C.U.4
Ozols, V.5
Fauq, A.6
Golde, T.E.7
Koo, E.H.8
-
78
-
-
84859496092
-
First and second generation gamma-secretase modulators (GSMs) modulate amyloid-beta (Abeta) peptide production through different mechanisms
-
T. Borgegard, A. Jureus, F. Olsson, S. Rosqvist, A. Sabirsh, and D. Rotticci et al. First and second generation gamma-secretase modulators (GSMs) modulate amyloid-beta (Abeta) peptide production through different mechanisms J Biol Chem 287 2012 11810 11819
-
(2012)
J Biol Chem
, vol.287
, pp. 11810-11819
-
-
Borgegard, T.1
Jureus, A.2
Olsson, F.3
Rosqvist, S.4
Sabirsh, A.5
Rotticci, D.6
-
79
-
-
0035829592
-
A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity
-
DOI 10.1038/35102591
-
S. Weggen, J.L. Eriksen, P. Das, S.A. Sagi, R. Wang, and C.U. Pietrzik et al. A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity Nature 414 2001 212 216 (Pubitemid 33051236)
-
(2001)
Nature
, vol.414
, Issue.6860
, pp. 212-216
-
-
Weggen, S.1
Eriksen, J.L.2
Das, P.3
Sagi, S.A.4
Wang, R.5
Pietrzik, C.U.6
Findlay, K.A.7
Smith, T.E.8
Murphy, M.P.9
Bulter, T.10
Kang, D.E.11
Marquez-Sterling, N.12
Golde, T.E.13
Koo, E.H.14
-
80
-
-
45149105232
-
Substrate-targeting gamma-secretase modulators
-
T.L. Kukar, T.B. Ladd, M.A. Bann, P.C. Fraering, R. Narlawar, and G.M. Maharvi et al. Substrate-targeting gamma-secretase modulators Nature 453 2008 925 929
-
(2008)
Nature
, vol.453
, pp. 925-929
-
-
Kukar, T.L.1
Ladd, T.B.2
Bann, M.A.3
Fraering, P.C.4
Narlawar, R.5
Maharvi, G.M.6
-
81
-
-
72549105935
-
Effect of tarenflurbil on cognitive decline and activities of daily living in patients with mild Alzheimer disease: A randomized controlled trial
-
R.C. Green, L.S. Schneider, D.A. Amato, A.P. Beelen, G. Wilcock, and E.A. Swabb et al. Effect of tarenflurbil on cognitive decline and activities of daily living in patients with mild Alzheimer disease: a randomized controlled trial JAMA 302 2009 2557 2564
-
(2009)
JAMA
, vol.302
, pp. 2557-2564
-
-
Green, R.C.1
Schneider, L.S.2
Amato, D.A.3
Beelen, A.P.4
Wilcock, G.5
Swabb, E.A.6
-
82
-
-
43249122280
-
Efficacy and safety of tarenflurbil in mild to moderate Alzheimer's disease: A randomised phase II trial
-
G.K. Wilcock, S.E. Black, S.B. Hendrix, K.H. Zavitz, E.A. Swabb, and M.A. Laughlin Efficacy and safety of tarenflurbil in mild to moderate Alzheimer's disease: a randomised phase II trial Lancet Neurol 7 2008 483 493
-
(2008)
Lancet Neurol
, vol.7
, pp. 483-493
-
-
Wilcock, G.K.1
Black, S.E.2
Hendrix, S.B.3
Zavitz, K.H.4
Swabb, E.A.5
Laughlin, M.A.6
-
83
-
-
46049108790
-
No advantage of A beta 42-lowering NSAIDs for prevention of Alzheimer dementia in six pooled cohort studies
-
C.A. Szekely, R.C. Green, J.C. Breitner, T. Ostbye, A.S. Beiser, and M.M. Corrada et al. No advantage of A beta 42-lowering NSAIDs for prevention of Alzheimer dementia in six pooled cohort studies Neurology 70 2008 2291 2298
-
(2008)
Neurology
, vol.70
, pp. 2291-2298
-
-
Szekely, C.A.1
Green, R.C.2
Breitner, J.C.3
Ostbye, T.4
Beiser, A.S.5
Corrada, M.M.6
-
84
-
-
0032549175
-
2 transport across the plasma membrane of HeLa cells and Xenopus oocytes expressing the prostaglandin transporter 'PGT'
-
DOI 10.1074/jbc.273.12.6689
-
B.S. Chan, J.A. Satriano, M. Pucci, and V.L. Schuster Mechanism of prostaglandin E2 transport across the plasma membrane of HeLa cells and Xenopus oocytes expressing the prostaglandin transporter "PGT" J Biol Chem 273 1998 6689 6697 (Pubitemid 28160327)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.12
, pp. 6689-6697
-
-
Chan, B.S.1
Satriano, J.A.2
Pucci, M.3
Schuster, V.L.4
-
85
-
-
0029078231
-
Identification and characterization of a prostaglandin transporter
-
N. Kanai, R. Lu, J.A. Satriano, Y. Bao, A.W. Wolkoff, and V.L. Schuster Identification and characterization of a prostaglandin transporter Science 268 1995 866 869
-
(1995)
Science
, vol.268
, pp. 866-869
-
-
Kanai, N.1
Lu, R.2
Satriano, J.A.3
Bao, Y.4
Wolkoff, A.W.5
Schuster, V.L.6
-
86
-
-
0029739973
-
Cloning, in vitro expression, and tissue distribution of a human prostaglandin transporter cDNA (hPGT)
-
R. Lu, N. Kanai, Y. Bao, and V.L. Schuster Cloning, in vitro expression, and tissue distribution of a human prostaglandin transporter cDNA(hPGT) J Clin Invest 98 1996 1142 1149 (Pubitemid 26299927)
-
(1996)
Journal of Clinical Investigation
, vol.98
, Issue.5
, pp. 1142-1149
-
-
Lu, R.1
Kanai, N.2
Bao, Y.3
Schuster, V.L.4
-
87
-
-
79953065448
-
Prostanoid signaling: Dual role for prostaglandin E2 in neurotoxicity
-
D. Milatovic, T.J. Montine, and M. Aschner Prostanoid signaling: dual role for prostaglandin E2 in neurotoxicity Neurotoxicology 32 2011 312 319
-
(2011)
Neurotoxicology
, vol.32
, pp. 312-319
-
-
Milatovic, D.1
Montine, T.J.2
Aschner, M.3
-
88
-
-
80054927472
-
Identification and development of mPGES-1 inhibitors: Where we are at?
-
H.H. Chang, and E.J. Meuillet Identification and development of mPGES-1 inhibitors: where we are at? Future Med Chem 3 2011 1909 1934
-
(2011)
Future Med Chem
, vol.3
, pp. 1909-1934
-
-
Chang, H.H.1
Meuillet, E.J.2
-
89
-
-
62249100641
-
EP(3) prostanoid receptor isoforms utilize distinct mechanisms to regulate ERK 1/2 activation
-
D.D. Israel, and J.W. Regan EP(3) prostanoid receptor isoforms utilize distinct mechanisms to regulate ERK 1/2 activation Biochim Biophys Acta 1791 2009 238 245
-
(2009)
Biochim Biophys Acta
, vol.1791
, pp. 238-245
-
-
Israel, D.D.1
Regan, J.W.2
-
90
-
-
84863422490
-
PGE2 EP1 receptor exacerbated neurotoxicity in a mouse model of cerebral ischemia and Alzheimer's disease
-
G. Zhen, Y.T. Kim, R.C. Li, J. Yocum, N. Kapoor, and J. Langer et al. PGE2 EP1 receptor exacerbated neurotoxicity in a mouse model of cerebral ischemia and Alzheimer's disease Neurobiol Aging 33 2012 2215 2219
-
(2012)
Neurobiol Aging
, vol.33
, pp. 2215-2219
-
-
Zhen, G.1
Kim, Y.T.2
Li, R.C.3
Yocum, J.4
Kapoor, N.5
Langer, J.6
-
91
-
-
77954604328
-
Suppressed accumulation of cerebral amyloid {beta} peptides in aged transgenic Alzheimer's disease mice by transplantation with wild-type or prostaglandin E2 receptor subtype 2-null bone marrow
-
C.D. Keene, R.C. Chang, A.H. Lopez-Yglesias, B.R. Shalloway, I. Sokal, and X. Li et al. Suppressed accumulation of cerebral amyloid {beta} peptides in aged transgenic Alzheimer's disease mice by transplantation with wild-type or prostaglandin E2 receptor subtype 2-null bone marrow Am J Pathol 177 2010 346 354
-
(2010)
Am J Pathol
, vol.177
, pp. 346-354
-
-
Keene, C.D.1
Chang, R.C.2
Lopez-Yglesias, A.H.3
Shalloway, B.R.4
Sokal, I.5
Li, X.6
-
92
-
-
27744462871
-
2 EP2 receptor reduces oxidative damage and amyloid burden in a model of Alzheimer's disease
-
DOI 10.1523/JNEUROSCI.3591-05.2005
-
X. Liang, Q. Wang, T. Hand, L. Wu, R.M. Breyer, and T.J. Montine et al. Deletion of the prostaglandin E2 EP2 receptor reduces oxidative damage and amyloid burden in a model of Alzheimer's disease J Neurosci 25 2005 10180 10187 (Pubitemid 41636214)
-
(2005)
Journal of Neuroscience
, vol.25
, Issue.44
, pp. 10180-10187
-
-
Liang, X.1
Wang, Q.2
Hand, T.3
Wu, L.4
Breyer, R.M.5
Montine, T.J.6
Andreasson, K.7
-
93
-
-
84862776580
-
Improvement of cognitive function in Alzheimer's disease model mice by genetic and pharmacological inhibition of the EP(4) receptor
-
T. Hoshino, T. Namba, M. Takehara, N. Murao, T. Matsushima, and Y. Sugimoto et al. Improvement of cognitive function in Alzheimer's disease model mice by genetic and pharmacological inhibition of the EP(4) receptor J Neurochem 120 2012 795 805
-
(2012)
J Neurochem
, vol.120
, pp. 795-805
-
-
Hoshino, T.1
Namba, T.2
Takehara, M.3
Murao, N.4
Matsushima, T.5
Sugimoto, Y.6
-
94
-
-
67650561188
-
Prostaglandin E2 stimulates the production of amyloid-beta peptides through internalization of the EP4 receptor
-
T. Hoshino, T. Namba, M. Takehara, T. Nakaya, Y. Sugimoto, and W. Araki et al. Prostaglandin E2 stimulates the production of amyloid-beta peptides through internalization of the EP4 receptor J Biol Chem 284 2009 18493 18502
-
(2009)
J Biol Chem
, vol.284
, pp. 18493-18502
-
-
Hoshino, T.1
Namba, T.2
Takehara, M.3
Nakaya, T.4
Sugimoto, Y.5
Araki, W.6
-
95
-
-
67049097402
-
Protection of hippocampal neurogenesis from toll-like receptor 4-dependent innate immune activation by ablation of prostaglandin E2 receptor subtype EP1 or EP2
-
C.D. Keene, R. Chang, C. Stephen, M. Nivison, S.E. Nutt, and A. Look et al. Protection of hippocampal neurogenesis from toll-like receptor 4-dependent innate immune activation by ablation of prostaglandin E2 receptor subtype EP1 or EP2 Am J Pathol 174 2009 2300 2309
-
(2009)
Am J Pathol
, vol.174
, pp. 2300-2309
-
-
Keene, C.D.1
Chang, R.2
Stephen, C.3
Nivison, M.4
Nutt, S.E.5
Look, A.6
-
96
-
-
84881134135
-
Prostaglandin E2 type 1 receptors contribute to neuronal apoptosis after transient forebrain ischemia
-
M. Shimamura, P. Zhou, B. Casolla, L. Qian, C. Capone, and H. Kurinami et al. Prostaglandin E2 type 1 receptors contribute to neuronal apoptosis after transient forebrain ischemia J Cereb Blood Flow Metab 33 2013 1207 1214
-
(2013)
J Cereb Blood Flow Metab
, vol.33
, pp. 1207-1214
-
-
Shimamura, M.1
Zhou, P.2
Casolla, B.3
Qian, L.4
Capone, C.5
Kurinami, H.6
-
97
-
-
58149172167
-
The neuroprotective effect of prostaglandin E2 EP1 receptor inhibition has a wide therapeutic window, is sustained in time and is not sexually dimorphic
-
T. Abe, A. Kunz, M. Shimamura, P. Zhou, J. Anrather, and C. Iadecola The neuroprotective effect of prostaglandin E2 EP1 receptor inhibition has a wide therapeutic window, is sustained in time and is not sexually dimorphic J Cereb Blood Flow Metab 29 2009 66 72
-
(2009)
J Cereb Blood Flow Metab
, vol.29
, pp. 66-72
-
-
Abe, T.1
Kunz, A.2
Shimamura, M.3
Zhou, P.4
Anrather, J.5
Iadecola, C.6
-
98
-
-
84874666077
-
Antagonism of neuronal prostaglandin E(2) receptor subtype 1 mitigates amyloid beta neurotoxicity in vitro
-
X. Li, S.E. Rose, K.S. Montine, C.D. Keene, and T.J. Montine Antagonism of neuronal prostaglandin E(2) receptor subtype 1 mitigates amyloid beta neurotoxicity in vitro J Neuroimmune Pharmacol 8 2013 87 93
-
(2013)
J Neuroimmune Pharmacol
, vol.8
, pp. 87-93
-
-
Li, X.1
Rose, S.E.2
Montine, K.S.3
Keene, C.D.4
Montine, T.J.5
-
99
-
-
0022967550
-
Multimodal assessment of impulsiveness in abusing, neglecting, and nonmaltreating mothers and their preschool children
-
DOI 10.1037/0022-006X.54.2.231
-
C.A. Rohrbeck, and C.T. Twentyman Multimodal assessment of impulsiveness in abusing, neglecting, and nonmaltreating mothers and their preschool children J Consult Clin Psychol 54 1986 231 236 (Pubitemid 17106022)
-
(1986)
Journal of Consulting and Clinical Psychology
, vol.54
, Issue.2
, pp. 231-236
-
-
Rohrbeck, C.A.1
Twentyman, C.T.2
-
100
-
-
84873433241
-
Ablation of the microglial protein DOCK2 reduces amyloid burden in a mouse model of Alzheimer's disease
-
P.J. Cimino, Y. Yang, X. Li, J.F. Hemingway, M.K. Cherne, and S.B. Khademi et al. Ablation of the microglial protein DOCK2 reduces amyloid burden in a mouse model of Alzheimer's disease Exp Mol Pathol 94 2013 366 371
-
(2013)
Exp Mol Pathol
, vol.94
, pp. 366-371
-
-
Cimino, P.J.1
Yang, Y.2
Li, X.3
Hemingway, J.F.4
Cherne, M.K.5
Khademi, S.B.6
-
101
-
-
64249094697
-
Impaired cognition, sensorimotor gating, and hippocampal long-term depression in mice lacking the prostaglandin E2 EP2 receptor
-
A. Savonenko, P. Munoz, T. Melnikova, Q. Wang, X. Liang, and R.M. Breyer et al. Impaired cognition, sensorimotor gating, and hippocampal long-term depression in mice lacking the prostaglandin E2 EP2 receptor Exp Neurol 217 2009 63 73
-
(2009)
Exp Neurol
, vol.217
, pp. 63-73
-
-
Savonenko, A.1
Munoz, P.2
Melnikova, T.3
Wang, Q.4
Liang, X.5
Breyer, R.M.6
-
102
-
-
77953638394
-
The prostaglandin E2 E-prostanoid 4 receptor exerts anti-inflammatory effects in brain innate immunity
-
J. Shi, J. Johansson, N.S. Woodling, Q. Wang, T.J. Montine, and K. Andreasson The prostaglandin E2 E-prostanoid 4 receptor exerts anti-inflammatory effects in brain innate immunity J Immunol 184 2010 7207 7218
-
(2010)
J Immunol
, vol.184
, pp. 7207-7218
-
-
Shi, J.1
Johansson, J.2
Woodling, N.S.3
Wang, Q.4
Montine, T.J.5
Andreasson, K.6
-
103
-
-
2942598274
-
2 regulates amyloid precursor protein expression via the EP2 receptor in cultured rat microglia
-
DOI 10.1016/j.neulet.2004.03.013, PII S0304394004002927
-
A.M. Pooler, A.A. Arjona, R.K. Lee, and R.J. Wurtman Prostaglandin E2 regulates amyloid precursor protein expression via the EP2 receptor in cultured rat microglia Neurosci Lett 362 2004 127 130 (Pubitemid 38759083)
-
(2004)
Neuroscience Letters
, vol.362
, Issue.2
, pp. 127-130
-
-
Pooler, A.M.1
Arjona, A.A.2
Lee, R.K.3
Wurtman, R.J.4
-
104
-
-
33847631662
-
2-EP3 receptors exacerbates stroke and excitotoxic injury
-
DOI 10.1016/j.jneuroim.2006.12.012, PII S0165572806005169, Inflammation, Neurodegeneration and Neuroprotection in the Central Nervous System
-
M. Ahmad, A.S. Ahmad, H. Zhuang, T. Maruyama, S. Narumiya, and S. Dore Stimulation of prostaglandin E2-EP3 receptors exacerbates stroke and excitotoxic injury J Neuroimmunol 184 2007 172 179 (Pubitemid 46365999)
-
(2007)
Journal of Neuroimmunology
, vol.184
, Issue.1-2
, pp. 172-179
-
-
Ahmad, M.1
Ahmad, A.S.2
Zhuang, H.3
Maruyama, T.4
Narumiya, S.5
Dore, S.6
-
105
-
-
84878880341
-
Targeting the EP1 receptor reduces Fas ligand expression and increases the antitumor immune response in an in vivo model of colon cancer
-
G. O'Callaghan, A. Ryan, P. Neary, C. O'Mahony, F. Shanahan, and A. Houston Targeting the EP1 receptor reduces Fas ligand expression and increases the antitumor immune response in an in vivo model of colon cancer Int J Cancer 133 2013 825 834
-
(2013)
Int J Cancer
, vol.133
, pp. 825-834
-
-
O'Callaghan, G.1
Ryan, A.2
Neary, P.3
O'Mahony, C.4
Shanahan, F.5
Houston, A.6
-
106
-
-
33646758221
-
Prostaglandin facilitates afferent nerve activity via EP1 receptors during urinary bladder inflammation in rats
-
M. Ikeda, M. Kawatani, T. Maruyama, and H. Ishihama Prostaglandin facilitates afferent nerve activity via EP1 receptors during urinary bladder inflammation in rats Biomed Res 27 2006 49 54
-
(2006)
Biomed Res
, vol.27
, pp. 49-54
-
-
Ikeda, M.1
Kawatani, M.2
Maruyama, T.3
Ishihama, H.4
-
107
-
-
0036898995
-
Differential peristaltic motor effects of prostanoid (DP, EP, IP, TP) and leukotriene receptor agonists in the guinea-pig isolated small intestine
-
DOI 10.1038/sj.bjp.0704958
-
A. Shahbazian, A. Heinemann, B.A. Peskar, and P. Holzer Differential peristaltic motor effects of prostanoid (DP, EP, IP, TP) and leukotriene receptor agonists in the guinea-pig isolated small intestine Br J Pharmacol 137 2002 1047 1054 (Pubitemid 35440745)
-
(2002)
British Journal of Pharmacology
, vol.137
, Issue.7
, pp. 1047-1054
-
-
Shahbazian, A.1
Heinemann, A.2
Peskar, B.A.3
Holzer, P.4
-
108
-
-
84872856839
-
Selectivity profiling of the novel EP2 receptor antagonist, PF-04418948, in functional bioassay systems: Atypical affinity at the guinea pig EP2 receptor
-
M.A. Birrell, S.A. Maher, J. Buckley, N. Dale, S. Bonvini, and K. Raemdonck et al. Selectivity profiling of the novel EP2 receptor antagonist, PF-04418948, in functional bioassay systems: atypical affinity at the guinea pig EP2 receptor Br J Pharmacol 168 2013 129 138
-
(2013)
Br J Pharmacol
, vol.168
, pp. 129-138
-
-
Birrell, M.A.1
Maher, S.A.2
Buckley, J.3
Dale, N.4
Bonvini, S.5
Raemdonck, K.6
-
109
-
-
84874831860
-
Differential regulation of airway smooth muscle cell migration by E-prostanoid receptor subtypes
-
H. Aso, S. Ito, A. Mori, N. Suganuma, M. Morioka, and N. Takahara et al. Differential regulation of airway smooth muscle cell migration by E-prostanoid receptor subtypes Am J Respir Cell Mol Biol 48 2013 322 329
-
(2013)
Am J Respir Cell Mol Biol
, vol.48
, pp. 322-329
-
-
Aso, H.1
Ito, S.2
Mori, A.3
Suganuma, N.4
Morioka, M.5
Takahara, N.6
-
110
-
-
81555216781
-
EP4 receptor as a new target for bronchodilator therapy
-
J. Buckley, M.A. Birrell, S.A. Maher, A.T. Nials, D.L. Clarke, and M.G. Belvisi EP4 receptor as a new target for bronchodilator therapy Thorax 66 2011 1029 1035
-
(2011)
Thorax
, vol.66
, pp. 1029-1035
-
-
Buckley, J.1
Birrell, M.A.2
Maher, S.A.3
Nials, A.T.4
Clarke, D.L.5
Belvisi, M.G.6
-
111
-
-
69249219009
-
Dual modulation of urinary bladder activity and urine flow by prostanoid EP3 receptors in the conscious rat
-
M.J. Jugus, J.P. Jaworski, P.B. Patra, J. Jin, D.M. Morrow, and N.J. Laping et al. Dual modulation of urinary bladder activity and urine flow by prostanoid EP3 receptors in the conscious rat Br J Pharmacol 158 2009 372 381
-
(2009)
Br J Pharmacol
, vol.158
, pp. 372-381
-
-
Jugus, M.J.1
Jaworski, J.P.2
Patra, P.B.3
Jin, J.4
Morrow, D.M.5
Laping, N.J.6
-
112
-
-
80052826881
-
Inhibition of prostaglandin E2 EP3 receptors improves stroke injury via anti-inflammatory and anti-apoptotic mechanisms
-
Y. Ikeda-Matsuo, H. Tanji, S. Narumiya, and Y. Sasaki Inhibition of prostaglandin E2 EP3 receptors improves stroke injury via anti-inflammatory and anti-apoptotic mechanisms J Neuroimmunol 238 2011 34 43
-
(2011)
J Neuroimmunol
, vol.238
, pp. 34-43
-
-
Ikeda-Matsuo, Y.1
Tanji, H.2
Narumiya, S.3
Sasaki, Y.4
-
113
-
-
33744549867
-
2 and other constrictor agents on rat femoral artery
-
DOI 10.1016/j.plefa.2006.04.002, PII S0952327806000524
-
G.H. Hung, R.L. Jones, F.F. Lam, K.M. Chan, H. Hidaka, and M. Suzuki et al. Investigation of the pronounced synergism between prostaglandin E2 and other constrictor agents on rat femoral artery Prostaglandins Leukot Essent Fatty Acids 74 2006 401 415 (Pubitemid 43816853)
-
(2006)
Prostaglandins Leukotrienes and Essential Fatty Acids
, vol.74
, Issue.6
, pp. 401-415
-
-
Hung, G.H.Y.1
Jones, R.L.2
Lam, F.F.Y.3
Chan, K.-M.4
Hidaka, H.5
Suzuki, M.6
Sasaki, Y.7
-
114
-
-
84858706509
-
Prostaglandin E(2) induced contraction of human intercostal arteries is mediated by the EP(3) receptor
-
D. Longrois, I. Gomez, N. Foudi, G. Topal, M. Dhaouadi, and L. Kotelevets et al. Prostaglandin E(2) induced contraction of human intercostal arteries is mediated by the EP(3) receptor Eur J Pharmacol 681 2012 55 59
-
(2012)
Eur J Pharmacol
, vol.681
, pp. 55-59
-
-
Longrois, D.1
Gomez, I.2
Foudi, N.3
Topal, G.4
Dhaouadi, M.5
Kotelevets, L.6
-
115
-
-
34249903093
-
Hematopoietic prostaglandin D synthase and DP1 receptor are selectively upregulated in microglia and astrocytes within senile plaques from human patients and in a mouse model of Alzheimer disease
-
DOI 10.1097/01.jnen.0000240472.43038.27, PII 0000507220070600000002
-
I. Mohri, K. Kadoyama, T. Kanekiyo, Y. Sato, K. Kagitani-Shimono, and Y. Saito et al. Hematopoietic prostaglandin D synthase and DP1 receptor are selectively upregulated in microglia and astrocytes within senile plaques from human patients and in a mouse model of Alzheimer disease J Neuropathol Exp Neurol 66 2007 469 480 (Pubitemid 46869689)
-
(2007)
Journal of Neuropathology and Experimental Neurology
, vol.66
, Issue.6
, pp. 469-480
-
-
Mohri, I.1
Kadoyama, K.2
Kanekiyo, T.3
Sato, Y.4
Kagitani-Shimono, K.5
Saito, Y.6
Suzuki, K.7
Kudo, T.8
Takeda, M.9
Urade, Y.10
Murayama, S.11
Taniike, M.12
-
116
-
-
33846594266
-
Determinants of platelet activation in Alzheimer's disease
-
DOI 10.1016/j.neurobiolaging.2005.12.011, PII S0197458005004562
-
G. Ciabattoni, E. Porreca, C. Di Febbo, A. Di Iorio, R. Paganelli, and T. Bucciarelli et al. Determinants of platelet activation in Alzheimer's disease Neurobiol Aging 28 2007 336 342 (Pubitemid 46177381)
-
(2007)
Neurobiology of Aging
, vol.28
, Issue.3
, pp. 336-342
-
-
Ciabattoni, G.1
Porreca, E.2
Di Febbo, C.3
Di Iorio, A.4
Paganelli, R.5
Bucciarelli, T.6
Pescara, L.7
Del Re, L.8
Giusti, C.9
Falco, A.10
Sau, A.11
Patrono, C.12
Davi, G.13
-
117
-
-
84856950778
-
Detrimental effects of arachidonic acid and its metabolites in cellular and mouse models of Alzheimer's disease: Structural insight
-
e21-31
-
Z. Amtul, M. Uhrig, L. Wang, R.F. Rozmahel, and K. Beyreuther Detrimental effects of arachidonic acid and its metabolites in cellular and mouse models of Alzheimer's disease: structural insight Neurobiol Aging 33 2012 831 e21-31
-
(2012)
Neurobiol Aging
, vol.33
, pp. 831
-
-
Amtul, Z.1
Uhrig, M.2
Wang, L.3
Rozmahel, R.F.4
Beyreuther, K.5
-
118
-
-
0026721865
-
Decreased prostaglandin synthesis in postmortem cerebral cortex from patients with Alzheimer's disease
-
P.T. Wong, P.L. McGeer, and E.G. McGeer Decreased prostaglandin synthesis in postmortem cerebral cortex from patients with Alzheimer's disease Neurochem Int 21 1992 197 202
-
(1992)
Neurochem Int
, vol.21
, pp. 197-202
-
-
Wong, P.T.1
McGeer, P.L.2
McGeer, E.G.3
-
119
-
-
34250854262
-
Lipocalin-type prostaglandin D synthase/β-trace is a major amyloid β-chaperone in human cerebrospinal fluid
-
DOI 10.1073/pnas.0701585104
-
T. Kanekiyo, T. Ban, K. Aritake, Z.L. Huang, W.M. Qu, and I. Okazaki et al. Lipocalin-type prostaglandin D synthase/beta-trace is a major amyloid beta-chaperone in human cerebrospinal fluid PNAS 104 2007 6412 6417 (Pubitemid 47186108)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.15
, pp. 6412-6417
-
-
Kanekiyo, T.1
Ban, T.2
Aritake, K.3
Huang, Z.-L.4
Qu, W.-M.5
Okazaki, I.6
Mohri, I.7
Murayama, S.8
Ozono, K.9
Taniike, M.10
Goto, Y.11
Urade, Y.12
-
120
-
-
44949103387
-
An aberrant protein complex in CSF as a biomarker of Alzheimer disease
-
M.A. Lovell, B.C. Lynn, S. Xiong, J.F. Quinn, J. Kaye, and W.R. Markesbery An aberrant protein complex in CSF as a biomarker of Alzheimer disease Neurology 70 2008 2212 2218
-
(2008)
Neurology
, vol.70
, pp. 2212-2218
-
-
Lovell, M.A.1
Lynn, B.C.2
Xiong, S.3
Quinn, J.F.4
Kaye, J.5
Markesbery, W.R.6
-
121
-
-
30744441143
-
2 mediates neuronal damage by amyloid-β or prions which activates microglial cells
-
DOI 10.1016/j.neuropharm.2005.09.008, PII S0028390805003515
-
C. Bate, S. Kempster, and A. Williams Prostaglandin D2 mediates neuronal damage by amyloid-beta or prions which activates microglial cells Neuropharmacology 50 2006 229 237 (Pubitemid 43100008)
-
(2006)
Neuropharmacology
, vol.50
, Issue.2
, pp. 229-237
-
-
Bate, C.1
Kempster, S.2
Williams, A.3
-
122
-
-
3242690571
-
2-isoprostanes levels in the patients with Alzheimer's disease
-
DOI 10.1016/j.brainresbull.2004.04.016, PII S0361923004001236
-
K.M. Kim, B.H. Jung, K.J. Paeng, I. Kim, and B.C. Chung Increased urinary F(2)-isoprostanes levels in the patients with Alzheimer's disease Brain Res Bull 64 2004 47 51 (Pubitemid 38953468)
-
(2004)
Brain Research Bulletin
, vol.64
, Issue.1
, pp. 47-51
-
-
Kim, K.M.1
Jung, B.H.2
Paeng, K.-J.3
Kim, I.4
Chung, B.C.5
-
124
-
-
84869753420
-
Brain-penetrant tetrahydronaphthalene thromboxane A2-prostanoid (TP) receptor antagonists as prototype therapeutics for Alzheimer's disease
-
J.H. Soper, S. Sugiyama, K. Herbst-Robinson, M.J. James, X. Wang, and J.Q. Trojanowski et al. Brain-penetrant tetrahydronaphthalene thromboxane A2-prostanoid (TP) receptor antagonists as prototype therapeutics for Alzheimer's disease ACS Chem Neurosci 3 2012 928 940
-
(2012)
ACS Chem Neurosci
, vol.3
, pp. 928-940
-
-
Soper, J.H.1
Sugiyama, S.2
Herbst-Robinson, K.3
James, M.J.4
Wang, X.5
Trojanowski, J.Q.6
-
125
-
-
44649118752
-
Thromboxane receptor activation mediates isoprostane-induced increases in amyloid pathology in Tg2576 mice
-
D.W. Shineman, B. Zhang, S.N. Leight, D. Pratico, and V.M. Lee Thromboxane receptor activation mediates isoprostane-induced increases in amyloid pathology in Tg2576 mice J Neurosci 28 2008 4785 4794
-
(2008)
J Neurosci
, vol.28
, pp. 4785-4794
-
-
Shineman, D.W.1
Zhang, B.2
Leight, S.N.3
Pratico, D.4
Lee, V.M.5
-
126
-
-
33845803191
-
Long-term efficacy and safety of celecoxib in Alzheimer's disease
-
DOI 10.1159/000096588
-
H. Soininen, C. West, J. Robbins, and L. Niculescu Long-term efficacy and safety of celecoxib in Alzheimer's disease Dement Geriatr Cogn Disord 23 2007 8 21 (Pubitemid 46005786)
-
(2007)
Dementia and Geriatric Cognitive Disorders
, vol.23
, Issue.1
, pp. 8-21
-
-
Soininen, H.1
West, C.2
Robbins, J.3
Niculescu, L.4
-
127
-
-
66849143701
-
A randomized controlled study on effects of ibuprofen on cognitive progression of Alzheimer's disease
-
P. Pasqualetti, C. Bonomini, G. Dal Forno, L. Paulon, E. Sinforiani, and C. Marra et al. A randomized controlled study on effects of ibuprofen on cognitive progression of Alzheimer's disease Aging Clin Exp Res 21 2009 102 110
-
(2009)
Aging Clin Exp Res
, vol.21
, pp. 102-110
-
-
Pasqualetti, P.1
Bonomini, C.2
Dal Forno, G.3
Paulon, L.4
Sinforiani, E.5
Marra, C.6
-
128
-
-
0034620538
-
A randomized controlled trial of prednisone in Alzheimer's disease
-
P.S. Aisen, K.L. Davis, J.D. Berg, K. Schafer, K. Campbell, and R.G. Thomas et al. A randomized controlled trial of prednisone in Alzheimer's disease. Alzheimer's Disease Cooperative Study Neurology 54 2000 588 593 (Pubitemid 30082922)
-
(2000)
Neurology
, vol.54
, Issue.3
, pp. 588-593
-
-
Aisen, P.S.1
Davis, K.L.2
Berg, J.D.3
Schafer, K.4
Campbell, K.5
Thomas, R.G.6
Weiner, M.F.7
Farlow, M.R.8
Sano, M.9
Grundman, M.10
Thal, L.J.11
-
129
-
-
0345830739
-
No effect on Alzheimer's disease in a 1-year, randomized, blinded, controlled study
-
S.A. Reines, G.A. Block, J.C. Morris, G. Liu, M.L. Nessly, and C.R. Lines et al. Rofecoxib: no effect on Alzheimer's disease in a 1-year, randomized, blinded, controlled study Neurology 62 2004 66 71 (Pubitemid 38082872)
-
(2004)
Neurology
, vol.62
, Issue.1
, pp. 66-71
-
-
Reines, S.A.1
Block, G.A.2
Morris, J.C.3
Liu, G.4
Nessly, M.L.5
Lines, C.R.6
Norman, B.A.7
Baranak, C.C.8
-
130
-
-
21144447586
-
A randomized, double-blind, study of rofecoxib in patients with mild cognitive impairment
-
DOI 10.1038/sj.npp.1300690
-
L.J. Thal, S.H. Ferris, L. Kirby, G.A. Block, C.R. Lines, and E. Yuen et al. A randomized, double-blind, study of rofecoxib in patients with mild cognitive impairment Neuropsychopharmacology 30 2005 1204 1215 (Pubitemid 40720980)
-
(2005)
Neuropsychopharmacology
, vol.30
, Issue.6
, pp. 1204-1215
-
-
Thal, L.J.1
Ferris, S.H.2
Kirby, L.3
Block, G.A.4
Lines, C.R.5
Yuen, E.6
Assaid, C.7
Nessly, M.L.8
Norman, B.A.9
Baranak, C.C.10
Reines, S.A.11
-
131
-
-
0037638809
-
Effects of Rofecoxib or Naproxen vs Placebo on Alzheimer Disease Progression: A Randomized Controlled Trial
-
P.S. Aisen, K.A. Schafer, M. Grundman, E. Pfeiffer, M. Sano, and K.L. Davis et al. Effects of rofecoxib or naproxen vs placebo on Alzheimer disease progression: a randomized controlled trial JAMA 289 2003 2819 2826 (Pubitemid 37430117)
-
(2003)
Journal of the American Medical Association
, vol.289
, Issue.21
, pp. 2819-2826
-
-
Aisen, P.S.1
Schafer, K.A.2
Grundman, M.3
Pfeiffer, E.4
Sano, M.5
Davis, K.L.6
Farlow, M.R.7
Jin, S.8
Thomas, R.G.9
Thal, L.J.10
-
132
-
-
43249085300
-
A randomized, double-blind, placebo controlled-trial of triflusal in mild cognitive impairment: The TRIMCI study
-
DOI 10.1097/WAD.0b013e3181611024, PII 0000209320080100000004
-
T. Gomez-Isla, R. Blesa, M. Boada, J. Clarimon, T. Del Ser, and G. Domenech et al. A randomized, double-blind, placebo controlled-trial of triflusal in mild cognitive impairment: the TRIMCI study Alzheimer Dis Assoc Disord 22 2008 21 29 (Pubitemid 351651394)
-
(2008)
Alzheimer Disease and Associated Disorders
, vol.22
, Issue.1
, pp. 21-29
-
-
Gomez-Isla, T.1
Blesa, R.2
Boada, M.3
Clarimon, J.4
Ser, T.D.5
Domenech, G.6
Ferro, J.M.7
Gomez-Anson, B.8
Manubens, J.M.9
Martinez-Lage, J.M.10
Munoz, D.11
Pena-Casanova, J.12
Torres, F.13
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