EAT-2, a SAP-like adaptor, controls NK cell activation through phospholipase Cγ, Ca++, and Erk, leading to granule polarization

Journal of Experimental Medicine

Volumn 211, Issue 4, 2014, Pages 727-742

  Pérez Quintero, Luis Alberto ^a,b   Roncagalli, Romain ^a,c   Guo, Huaijian ^a,b   Latour, Sylvain ^d   Davidson, Dominique ^a   Veillette, André ^a,b,c  

^a CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

^d IMAGINE INSTITUTE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; CALCIUM ION; EWING SARCOMA ASSOCIATED TRANSCRIPT 2; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOLIPASE C GAMMA; PROTEIN TYROSINE PHOSPHATASE SHP; TYROSINE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CARBOXY TERMINAL SEQUENCE; CELL ACTIVATION; CELL MEDIATED CYTOTOXICITY; CELL POLARITY; CONJUGATION; CONTROLLED STUDY; ENZYME ACTIVATION; EXOCYTOSIS; EXON; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; INTRON; MOLECULAR IMAGING; MOUSE; MOUSE STRAIN; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; ANIMALS; CALCIUM; CYTOPLASMIC GRANULES; ENZYME ACTIVATION; EXOCYTOSIS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KILLER CELLS, NATURAL; LYMPHOCYTE ACTIVATION; MICE; MOLECULAR SEQUENCE DATA; PHOSPHOLIPASE C GAMMA; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION FACTORS; TYROSINE;

EID: 84897946263     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20132038     Document Type: Article

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