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Volumn 12, Issue 5, 2011, Pages 425-433

STIM1, PKC-δ and RasGRP set a threshold for proapoptotic Erk signaling during B cell development

Author keywords

[No Author keywords available]

Indexed keywords

DIACYLGLYCEROL; GUANINE NUCLEOTIDE EXCHANGE FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE C DELTA; STROMAL INTERACTION MOLECULE 1;

EID: 79955004049     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.2016     Document Type: Article
Times cited : (113)

References (51)
  • 1
    • 0027499537 scopus 로고
    • Receptor editing: An approach by autoreactive B cells to escape tolerance
    • Gay, D., Saunders, T., Camper, S. & Weigert, M. Receptor editing: an approach by autoreactive B cells to escape tolerance. J. Exp. Med. 177, 999-1008 (1993). (Pubitemid 23097389)
    • (1993) Journal of Experimental Medicine , vol.177 , Issue.4 , pp. 999-1008
    • Gay, D.1    Saunders, T.2    Camper, S.3    Weigert, M.4
  • 2
    • 0023729241 scopus 로고
    • Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice
    • Goodnow, C.C. et al. Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice. Nature 334, 676-682 (1988).
    • (1988) Nature , vol.334 , pp. 676-682
    • Goodnow, C.C.1
  • 3
    • 0024529870 scopus 로고
    • Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes
    • DOI 10.1038/337562a0
    • Nemazee, D.A. & Burki, K. Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes. Nature 337, 562-566 (1989). (Pubitemid 19045542)
    • (1989) Nature , vol.337 , Issue.6207 , pp. 562-566
    • Nemazee, D.A.1    Burki, K.2
  • 6
    • 0030981639 scopus 로고    scopus 로고
    • - bone marrow B cells in vitro
    • Hertz, M. & Nemazee, D. BCR ligation induces receptor editing in IgM+IgD? bone marrow B cells in vitro. Immunity 6, 429-436 (1997). (Pubitemid 27208198)
    • (1997) Immunity , vol.6 , Issue.4 , pp. 429-436
    • Hertz, M.1    Nemazee, D.2
  • 7
    • 0032559223 scopus 로고    scopus 로고
    • Developmental regulation of B lymphocyte immune tolerance compartmentalizes clonal selection from receptor selection
    • DOI 10.1016/S0092-8674(00)80912-5
    • Melamed, D., Benschop, R.J., Cambier, J.C. & Nemazee, D. Developmental regulation of B lymphocyte immune tolerance compartmentalizes clonal selection from receptor selection. Cell 92, 173-182 (1998). (Pubitemid 28073041)
    • (1998) Cell , vol.92 , Issue.2 , pp. 173-182
    • Melamed, D.1    Benschop, R.J.2    Cambier, J.C.3    Nemazee, D.4
  • 8
    • 0035887778 scopus 로고    scopus 로고
    • Unique signaling properties, of B cell antigen receptor in mature and immature B cells: Implications for tolerance and activation
    • Benschop, R.J., Brandl, E., Chan, A.C. & Cambier, J.C. Unique signaling properties of B cell antigen receptor in mature and immature B cells: implications for tolerance and activation. J. Immunol. 167, 4172-4179 (2001). (Pubitemid 32954289)
    • (2001) Journal of Immunology , vol.167 , Issue.8 , pp. 4172-4179
    • Benschop, R.J.1    Brandl, E.2    Chan, A.C.3    Cambier, J.C.4
  • 9
    • 66949130737 scopus 로고    scopus 로고
    • Developmental acquisition of the Lyn-CD22-SHP-1 inhibitory pathway promotes B cell tolerance
    • Gross, A.J., Lyandres, J.R., Panigrahi, A.K., Prak, E.T. & DeFranco, A.L. Developmental acquisition of the Lyn-CD22-SHP-1 inhibitory pathway promotes B cell tolerance. J. Immunol. 182, 5382-5392 (2009).
    • (2009) J. Immunol. , vol.182 , pp. 5382-5392
    • Gross, A.J.1    Lyandres, J.R.2    Panigrahi, A.K.3    Prak, E.T.4    Defranco, A.L.5
  • 10
  • 11
    • 0033105841 scopus 로고    scopus 로고
    • Antigen receptor-induced signal transduction imbalances associated with the negative selection of immature B cells
    • King, L.B., Norvell, A. & Monroe, J.G. Antigen receptor-induced signal transduction imbalances associated with the negative selection of immature B cells. J. Immunol. 162, 2655-2662 (1999). (Pubitemid 29309286)
    • (1999) Journal of Immunology , vol.162 , Issue.5 , pp. 2655-2662
    • King, L.B.1    Norvell, A.2    Monroe, J.G.3
  • 12
    • 15544368216 scopus 로고    scopus 로고
    • Store-operated calcium channels
    • DOI 10.1152/physrev.00057.2003
    • Parekh, A.B. & Putney, J.W. Jr. Store-operated calcium channels. Physiol. Rev. 85, 757-810 (2005). (Pubitemid 40404641)
    • (2005) Physiological Reviews , vol.85 , Issue.2 , pp. 757-810
    • Parekh, A.B.1    Putney Jr., J.W.2
  • 17
    • 33748548406 scopus 로고    scopus 로고
    • 2+ entry: Local activation of CRAC channels by STIM1 at ER-plasma membrane junctions
    • DOI 10.1083/jcb.200604015
    • Luik, R.M., Wu, M.M., Buchanan, J. & Lewis, R.S. The elementary unit of store-operated Ca2+ entry: local activation of CRAC channels by STIM1 at ER-plasma membrane junctions. J. Cell Biol. 174, 815-825 (2006). (Pubitemid 44373731)
    • (2006) Journal of Cell Biology , vol.174 , Issue.6 , pp. 815-825
    • Luik, R.M.1    Wu, M.M.2    Buchanan, J.3    Lewis, R.S.4
  • 18
    • 61349137530 scopus 로고    scopus 로고
    • STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1
    • Park, C.Y. et al. STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1. Cell 136, 876-890 (2009).
    • (2009) Cell , vol.136 , pp. 876-890
    • Park, C.Y.1
  • 19
    • 33645217935 scopus 로고    scopus 로고
    • STIM1 has a plasma membrane role in the activation of store-operated Ca2+ channels
    • Spassova, M.A. et al. STIM1 has a plasma membrane role in the activation of store-operated Ca2+ channels. Proc. Natl. Acad. Sci. USA 103, 4040-4045 (2006).
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 4040-4045
    • Spassova, M.A.1
  • 20
    • 33748569838 scopus 로고    scopus 로고
    • 2+ store depletion causes STIM1 to accumulate in ER regions closely associated with the plasma membrane
    • DOI 10.1083/jcb.200604014
    • Wu, M.M., Buchanan, J., Luik, R.M. & Lewis, R.S. Ca2+ store depletion causes STIM1 to accumulate in ER regions closely associated with the plasma membrane. J. Cell Biol. 174, 803-813 (2006). (Pubitemid 44373730)
    • (2006) Journal of Cell Biology , vol.174 , Issue.6 , pp. 803-813
    • Wu, M.M.1    Buchanan, J.2    Luik, R.M.3    Lewis, R.S.4
  • 21
    • 0037171439 scopus 로고    scopus 로고
    • Protein kinase Cδ controls self-antigen-induced B-cell tolerance
    • DOI 10.1038/416860a
    • Mecklenbrauker, I., Saijo, K., Zheng, N.Y., Leitges, M. & Tarakhovsky, A. Protein kinase Controls self-antigen-induced B-cell tolerance. Nature 416, 860-865 (2002). (Pubitemid 34453743)
    • (2002) Nature , vol.416 , Issue.6883 , pp. 860-865
    • Mecklenbrauker, I.1    Saijo, K.2    Zheng, N.-Y.3    Leitges, M.4    Tarakhovsky, A.5
  • 23
    • 0034303371 scopus 로고    scopus 로고
    • RasGRP is essential for mouse thymocyte differentiation and TCR signaling
    • Dower, N.A. et al. RasGRP is essential for mouse thymocyte differentiation and TCR signaling. Nat. Immunol. 1, 317-321 (2000).
    • (2000) Nat. Immunol. , vol.1 , pp. 317-321
    • Dower, N.A.1
  • 24
    • 0034303470 scopus 로고    scopus 로고
    • T cells: Getting a GRP on Ras
    • Roose, J. & Weiss, A. T cells: getting a GRP on Ras. Nat. Immunol. 1, 275-276 (2000).
    • (2000) Nat. Immunol. , vol.1 , pp. 275-276
    • Roose, J.1    Weiss, A.2
  • 25
    • 18944383647 scopus 로고    scopus 로고
    • A diacylglycerol-protein kinase C-RasGRP1 pathway directs Ras activation upon antigen receptor stimulation of T cells
    • DOI 10.1128/MCB.25.11.4426-4441.2005
    • Roose, J.P., Mollenauer, M., Gupta, V.A., Stone, J. & Weiss, A. A diacylglycerol-protein kinase C-RasGRP1 pathway directs Ras activation upon antigen receptor stimulation of T cells. Mol. Cell. Biol. 25, 4426-4441 (2005). (Pubitemid 40705750)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.11 , pp. 4426-4441
    • Roose, J.P.1    Mollenauer, M.2    Gupta, V.A.3    Stone, J.4    Weiss, A.5
  • 26
    • 0042237772 scopus 로고    scopus 로고
    • Integration of DAG signaling systems mediated by PKC-dependent phosphorylation of RasGRP3
    • DOI 10.1182/blood-2002-11-3621
    • Teixeira, C., Stang, S.L., Zheng, Y., Beswick, N.S. & Stone, J.C. Integration of DAG signaling systems mediated by PKC-dependent phosphorylation of RasGRP3. Blood 102, 1414-1420 (2003). (Pubitemid 36988051)
    • (2003) Blood , vol.102 , Issue.4 , pp. 1414-1420
    • Teixeira, C.1    Stang, S.L.2    Zheng, Y.3    Beswick, N.S.4    Stone, J.C.5
  • 28
    • 0042383362 scopus 로고    scopus 로고
    • Enhanced T cell responses due to diacylglycerol kinase zeta deficiency
    • Zhong, X.P. et al. Enhanced T cell responses due to diacylglycerol kinase zeta deficiency. Nat. Immunol. 4, 882-890 (2003).
    • (2003) Nat. Immunol. , vol.4 , pp. 882-890
    • Zhong, X.P.1
  • 29
    • 58249092059 scopus 로고    scopus 로고
    • Digital signaling and hysteresis characterize ras activation in lymphoid cells
    • Das, J. et al. Digital signaling and hysteresis characterize ras activation in lymphoid cells. Cell 136, 337-351 (2009).
    • (2009) Cell , vol.136 , pp. 337-351
    • Das, J.1
  • 30
    • 0032524389 scopus 로고    scopus 로고
    • RasGRP, a Ras guanyl nucleotide- releasing protein with calcium- and diacylglycerol-binding motifs
    • DOI 10.1126/science.280.5366.1082
    • Ebinu, J.O. et al. RasGRP, A Ras guanyl nucleotide-releasing protein with calcium-and diacylglycerol-binding motifs. Science 280, 1082-1086 (1998). (Pubitemid 28234950)
    • (1998) Science , vol.280 , Issue.5366 , pp. 1082-1086
    • Ebinu, J.O.1    Bottorff, D.A.2    Chan, E.Y.W.3    Stang, S.L.4    Dunn, R.J.5    Stone, J.C.6
  • 32
    • 0347593996 scopus 로고    scopus 로고
    • Requirement for Ras guanine nucleotide releasing protein 3 in coupling phospholipase C-γ2 to Ras in B cell receptor signaling
    • DOI 10.1084/jem.20031547
    • Oh-hora, M., Johmura, S., Hashimoto, A., Hikida, M. & Kurosaki, T. Requirement for Ras guanine nucleotide releasing protein 3 in coupling phospholipase C-γ2 to Ras in B cell receptor signaling. J. Exp. Med. 198, 1841-1851 (2003). (Pubitemid 38032117)
    • (2003) Journal of Experimental Medicine , vol.198 , Issue.12 , pp. 1841-1851
    • Oh-Hora, M.1    Johmura, S.2    Hashimoto, A.3    Hikida, M.4    Kurosaki, T.5
  • 33
    • 34147203741 scopus 로고    scopus 로고
    • Unusual interplay of two types of Ras activators, RasGRP and SOS, establishes sensitive and robust Ras activation in lymphocytes
    • DOI 10.1128/MCB.01882-06
    • Roose, J.P., Mollenauer, M., Ho, M., Kurosaki, T. & Weiss, A. Unusual interplay of two types of Ras activators, RasGRP and SOS, Establishes sensitive and robust Ras activation in lymphocytes. Mol. Cell. Biol. 27, 2732-2745 (2007). (Pubitemid 46581361)
    • (2007) Molecular and Cellular Biology , vol.27 , Issue.7 , pp. 2732-2745
    • Roose, J.P.1    Mollenauer, M.2    Ho, M.3    Kurosaki, T.4    Weiss, A.5
  • 34
    • 2442421056 scopus 로고    scopus 로고
    • RasGRP1 Sensitizes an Immature B Cell Line to Antigen Receptor-induced Apoptosis
    • DOI 10.1074/jbc.M314273200
    • Guilbault, B. & Kay, R.J. RasGRP1 sensitizes an immature B cell line to antigen receptor-induced apoptosis. J. Biol. Chem. 279, 19523-19530 (2004). (Pubitemid 38623387)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.19 , pp. 19523-19530
    • Guilbault, B.1    Kay, R.J.2
  • 35
    • 57549117975 scopus 로고    scopus 로고
    • A proapoptotic signaling pathway involving RasGRP, Erk, and Bim in B cells
    • Stang, S.L. et al. A proapoptotic signaling pathway involving RasGRP, Erk, And Bim in B cells. Exp. Hematol. 37, 122-134 (2009).
    • (2009) Exp. Hematol. , vol.37 , pp. 122-134
    • Stang, S.L.1
  • 37
    • 18244409902 scopus 로고    scopus 로고
    • Phosphorylation of RasGRP3 on threonine 133 provides a mechanistic link between PKC and Ras signaling systems in B cells
    • DOI 10.1182/blood-2004-10-3916
    • Zheng, Y. et al. Phosphorylation of RasGRP3 on threonine 133 provides a mechanistic link between PKC and Ras signaling systems in B cells. Blood 105, 3648-3654 (2005). (Pubitemid 40628212)
    • (2005) Blood , vol.105 , Issue.9 , pp. 3648-3654
    • Zheng, Y.1    Liu, H.2    Coughlin, J.3    Zheng, J.4    Li, L.5    Stone, J.C.6
  • 39
    • 0033579464 scopus 로고    scopus 로고
    • Sequence and structure-based prediction of eukaryotic protein phosphorylation sites
    • DOI 10.1006/jmbi.1999.3310
    • Blom, N., Gammeltoft, S. & Brunak, S. Sequence and structure-based prediction of eukaryotic protein phosphorylation sites. J. Mol. Biol. 294, 1351-1362 (1999). (Pubitemid 30008805)
    • (1999) Journal of Molecular Biology , vol.294 , Issue.5 , pp. 1351-1362
    • Blom, N.1    Gammeltoft, S.2    Brunak, S.3
  • 42
    • 4644240851 scopus 로고    scopus 로고
    • Regulation of B-cell survival by BAFF-dependent PKCδ-mediated nuclear signalling
    • DOI 10.1038/nature02955
    • Mecklenbrauker, I., Kalled, S.L., Leitges, M., Mackay, F. & Tarakhovsky, A. Regulation of B-cell survival by BAFF-dependent PKC?-mediated nuclear signalling. Nature 431, 456-461 (2004). (Pubitemid 39329585)
    • (2004) Nature , vol.431 , Issue.7007 , pp. 456-461
    • Mecklenbrauker, I.1    Kalled, S.L.2    Lettges, M.3    Mackay, F.4    Tarakhovsky, A.5
  • 43
    • 10944238407 scopus 로고    scopus 로고
    • Distinctive activation mechanisms and functions for protein kinase Cδ
    • DOI 10.1042/BJ20040704
    • Steinberg, S.F. Distinctive activation mechanisms and functions for protein kinase C?. Biochem. J. 384, 449-459 (2004). (Pubitemid 40018958)
    • (2004) Biochemical Journal , vol.384 , Issue.3 , pp. 449-459
    • Steinberg, S.F.1
  • 44
    • 33947236005 scopus 로고    scopus 로고
    • PKCδ signaling: Mechanisms of DNA damage response and apoptosis
    • DOI 10.1016/j.cellsig.2007.01.027, PII S0898656807000435
    • Yoshida, K. PKCsignaling: mechanisms of DNA damage response and apoptosis. Cell. Signal. 19, 892-901 (2007). (Pubitemid 46436445)
    • (2007) Cellular Signalling , vol.19 , Issue.5 , pp. 892-901
    • Yoshida, K.1
  • 45
    • 0027447188 scopus 로고
    • Elimination of self-reactive B lymphocytes proceeds in two stages: Arrested development and cell death
    • DOI 10.1016/0092-8674(93)90111-3
    • Hartley, S.B. et al. Elimination of self-reactive B lymphocytes proceeds in two stages: arrested development and cell death. Cell 72, 325-335 (1993). (Pubitemid 23059404)
    • (1993) Cell , vol.72 , Issue.3 , pp. 325-335
    • Hartley, S.B.1    Cooke, M.P.2    Fulcher, D.A.3    Harris, A.W.4    Cory, S.5    Basten, A.6    Goodnow, C.C.7
  • 46
    • 0025948793 scopus 로고
    • Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens
    • Hartley, S.B. et al. Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens. Nature 353, 765-769 (1991). (Pubitemid 21912617)
    • (1991) Nature , vol.353 , Issue.6346 , pp. 765-769
    • Hartley, S.B.1    Crosbie, J.2    Brink, R.3    Kantor, A.B.4    Basten, A.5    Goodnow, C.C.6
  • 47
    • 58149187996 scopus 로고    scopus 로고
    • Differences in flexibility underlie functional differences in the Ras activators son of sevenless and Ras guanine nucleotide releasing factor 1
    • Freedman, T.S. et al. Differences in flexibility underlie functional differences in the Ras activators son of sevenless and Ras guanine nucleotide releasing factor 1. Structure 17, 41-53 (2009).
    • (2009) Structure , vol.17 , pp. 41-53
    • Freedman, T.S.1
  • 48
    • 27644575157 scopus 로고    scopus 로고
    • Coordinating ERK/MAPK signalling through scaffolds and inhibitors
    • DOI 10.1038/nrm1743, PII N1743
    • Kolch, W. Coordinating ERK/MAPK signalling through scaffolds and inhibitors. Nat. Rev. Mol. Cell Biol. 6, 827-837 (2005). (Pubitemid 41568732)
    • (2005) Nature Reviews Molecular Cell Biology , vol.6 , Issue.11 , pp. 827-837
    • Kolch, W.1
  • 49
    • 33646336602 scopus 로고    scopus 로고
    • MAPK signal specificity: The right place at the right time
    • DOI 10.1016/j.jsg.2005.10.009, PII S0968000406000867
    • Murphy, L.O. & Blenis, J. MAPK signal specificity: the right place at the right time. Trends Biochem. Sci. 31, 268-275 (2006). (Pubitemid 43674354)
    • (2006) Trends in Biochemical Sciences , vol.31 , Issue.5 , pp. 268-275
    • Murphy, L.O.1    Blenis, J.2
  • 50
    • 23844500699 scopus 로고    scopus 로고
    • Compartmentalized signalling of Ras
    • DOI 10.1042/BST0330657
    • Philips, M.R. Compartmentalized signalling of Ras. Biochem. Soc. Trans. 33, 657-661 (2005). (Pubitemid 41160832)
    • (2005) Biochemical Society Transactions , vol.33 , Issue.4 , pp. 657-661
    • Philips, M.R.1


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