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Volumn 28, Issue 4, 2014, Pages 442-457

Progesterone receptor-cyclin D1 complexes induce cell cycle-dependent transcriptional programs in breast cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

ANTIESTROGEN; ANTIGESTAGEN; CYCLIN D1; CYCLIN DEPENDENT KINASE 2; GESTAGEN; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 22; LIGAND; MESSENGER RNA; PROGESTERONE RECEPTOR; ROSCOVITINE; TAMOXIFEN; TRANSCRIPTION FACTOR SP1; CDK2 PROTEIN, HUMAN; CELL EXTRACT; HSPB8 PROTEIN, HUMAN; PHOSPHOSERINE; PROTEIN SERINE THREONINE KINASE;

EID: 84897944038     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2013-1196     Document Type: Article
Times cited : (33)

References (83)
  • 1
    • 0029111934 scopus 로고
    • Cyclin D1 provides a link between development and oncogenesis in the retina and breast
    • Sicinski P, Donaher JL, Parker SB, et al. Cyclin D1 provides a link between development and oncogenesis in the retina and breast. Cell. 1995; 82: 621-630.
    • (1995) Cell , vol.82 , pp. 621-630
    • Sicinski, P.1    Donaher, J.L.2    Parker, S.B.3
  • 2
    • 0042693019 scopus 로고    scopus 로고
    • Defective mammary gland morphogenesis in mice lacking the progesterone receptor B isoform
    • Mulac-Jericevic B, Lydon JP, DeMayo FJ, Conneely OM. Defective mammary gland morphogenesis in mice lacking the progesterone receptor B isoform. Proc Natl Acad Sci USA. 2003; 100: 9744-9749.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 9744-9749
    • Mulac-Jericevic, B.1    Lydon, J.P.2    DeMayo, F.J.3    Conneely, O.M.4
  • 3
    • 77649259667 scopus 로고    scopus 로고
    • Two distinct mechanisms underlie progesterone-induced proliferation in the mammary gland
    • Beleut M, Rajaram RD, Caikovski M, et al. Two distinct mechanisms underlie progesterone-induced proliferation in the mammary gland. Proc Natl Acad Sci USA. 2010; 107: 2989-2994.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 2989-2994
    • Beleut, M.1    Rajaram, R.D.2    Caikovski, M.3
  • 4
    • 0032771839 scopus 로고    scopus 로고
    • Overexpression of cyclin D1 messenger RNA predicts for poor prognosis in estrogen receptorpositive breast cancer
    • Kenny FS, Hui R, Musgrove EA, et al. Overexpression of cyclin D1 messenger RNA predicts for poor prognosis in estrogen receptorpositive breast cancer. Clin Cancer Res. 1999; 5: 2069-2076.
    • (1999) Clin Cancer Res , vol.5 , pp. 2069-2076
    • Kenny, F.S.1    Hui, R.2    Musgrove, E.A.3
  • 5
    • 23044508946 scopus 로고    scopus 로고
    • Cyclin D1 in breast cancer pathogenesis
    • Arnold A, Papanikolaou A. Cyclin D1 in breast cancer pathogenesis. J Clin Oncol. 2005; 23: 4215-4224.
    • (2005) J Clin Oncol , vol.23 , pp. 4215-4224
    • Arnold, A.1    Papanikolaou, A.2
  • 6
    • 33846138978 scopus 로고    scopus 로고
    • Progesterone receptors upregulate Wnt-1 to induce epidermal growth factor receptor transactivation and c-Srcdependent sustained activation of Erk1/2 mitogen-activated protein kinase in breast cancer cells
    • Faivre EJ, Lange CA. Progesterone receptors upregulate Wnt-1 to induce epidermal growth factor receptor transactivation and c-Srcdependent sustained activation of Erk1/2 mitogen-activated protein kinase in breast cancer cells. Mol Cell Biol. 2007; 27: 466-480.
    • (2007) Mol Cell Biol , vol.27 , pp. 466-480
    • Faivre, E.J.1    Lange, C.A.2
  • 7
    • 84860540830 scopus 로고    scopus 로고
    • Estrogen receptor α mediates progestin-induced mammary tumor growth by interacting with progesterone receptors at the cyclin D1/MYC promoters
    • Giulianelli S, Vaqué JP, Soldati R, et al. Estrogen receptor α mediates progestin-induced mammary tumor growth by interacting with progesterone receptors at the cyclin D1/MYC promoters. Cancer Res. 2012; 72: 2416-2427.
    • (2012) Cancer Res , vol.72 , pp. 2416-2427
    • Giulianelli, S.1    Vaqué, J.P.2    Soldati, R.3
  • 8
    • 0034458854 scopus 로고    scopus 로고
    • Regulation of the functional interaction between cyclin D1 and the estrogen receptor
    • Lamb J, Ladha MH, McMahon C, Sutherland RL, Ewen ME. Regulation of the functional interaction between cyclin D1 and the estrogen receptor. Mol Cell Biol. 2000; 20: 8667-8675.
    • (2000) Mol Cell Biol , vol.20 , pp. 8667-8675
    • Lamb, J.1    Ladha, M.H.2    McMahon, C.3    Sutherland, R.L.4    Ewen, M.E.5
  • 9
    • 0030968438 scopus 로고    scopus 로고
    • CDK-independent activation of estrogen receptor by cyclin D1
    • Zwijsen RM, Wientjens E, Klompmaker R, et al. CDK-independent activation of estrogen receptor by cyclin D1. Cell. 1997; 88: 405-415.
    • (1997) Cell , vol.88 , pp. 405-415
    • Zwijsen, R.M.1    Wientjens, E.2    Klompmaker, R.3
  • 10
    • 0032533881 scopus 로고    scopus 로고
    • Ligand-independent recruitment of steroid receptor coactivators to estrogen receptor by cyclin D1
    • Zwijsen RM, Buckle RS, Hijmans EM, Loomans CJ, Bernards R. Ligand-independent recruitment of steroid receptor coactivators to estrogen receptor by cyclin D1. Genes Dev. 1998; 12: 3488-3498.
    • (1998) Genes Dev , vol.12 , pp. 3488-3498
    • Zwijsen, R.M.1    Buckle, R.S.2    Hijmans, E.M.3    Loomans, C.J.4    Bernards, R.5
  • 11
    • 14844333265 scopus 로고    scopus 로고
    • 2-terminal domain inhibits activation of function 2 association and reveals dual roles for AR corepression
    • 2-terminal domain inhibits activation of function 2 association and reveals dual roles for AR corepression. Mol Endocrinol. 2005; 19: 607-620.
    • (2005) Mol Endocrinol , vol.19 , pp. 607-620
    • Burd, C.J.1    Petre, C.E.2    Moghadam, H.3    Wilson, E.M.4    Knudsen, K.E.5
  • 12
    • 13244256871 scopus 로고    scopus 로고
    • A central domain of cyclin D1 mediates nuclear receptor corepressor activity
    • Petre-Draviam CE, Williams EB, Burd CJ, et al. A central domain of cyclin D1 mediates nuclear receptor corepressor activity. Oncogene. 2005; 24: 431-444.
    • (2005) Oncogene , vol.24 , pp. 431-444
    • Petre-Draviam, C.E.1    Williams, E.B.2    Burd, C.J.3
  • 13
    • 67349168694 scopus 로고    scopus 로고
    • Signaling inputs to progesterone receptor gene regulation and promoter selectivity
    • Daniel AR, Knutson TP, Lange CA. Signaling inputs to progesterone receptor gene regulation and promoter selectivity. Mol Cell Endocrinol. 2009; 308: 47-52.
    • (2009) Mol Cell Endocrinol , vol.308 , pp. 47-52
    • Daniel, A.R.1    Knutson, T.P.2    Lange, C.A.3
  • 14
    • 0030775651 scopus 로고    scopus 로고
    • Biphasic regulation of breast cancer cell growth by progesterone: Role of the cyclin-dependent kinase inhibitors, p21 and p27(Kip1)
    • Groshong SD, Owen GI, Grimison B, et al. Biphasic regulation of breast cancer cell growth by progesterone: role of the cyclin-dependent kinase inhibitors, p21 and p27(Kip1). Mol Endocrinol. 1997; 11: 1593-1607.
    • (1997) Mol Endocrinol , vol.11 , pp. 1593-1607
    • Groshong, S.D.1    Owen, G.I.2    Grimison, B.3
  • 15
    • 18144432142 scopus 로고    scopus 로고
    • Integration of progesterone receptor mediated rapid signaling and nuclear actions in breast cancer cell models: Role of mitogen-activated protein kinases and cell cycle regulators
    • Faivre E, Skildum A, Pierson-Mullany L, Lange CA. Integration of progesterone receptor mediated rapid signaling and nuclear actions in breast cancer cell models: role of mitogen-activated protein kinases and cell cycle regulators. Steroids. 2005; 70: 418-426.
    • (2005) Steroids , vol.70 , pp. 418-426
    • Faivre, E.1    Skildum, A.2    Pierson-Mullany, L.3    Lange, C.A.4
  • 16
    • 11144274562 scopus 로고    scopus 로고
    • Cyclin-dependent kinase activity is required for progesterone receptor function: Novel role for cyclin A/Cdk2 as a progesterone receptor coactivator
    • Narayanan R, Adigun AA, Edwards DP, Weigel NL. Cyclin-dependent kinase activity is required for progesterone receptor function: novel role for cyclin A/Cdk2 as a progesterone receptor coactivator. Mol Cell Biol. 2005; 25: 264-277.
    • (2005) Mol Cell Biol , vol.25 , pp. 264-277
    • Narayanan, R.1    Adigun, A.A.2    Edwards, D.P.3    Weigel, N.L.4
  • 17
    • 33847066362 scopus 로고    scopus 로고
    • Cyclin dependent kinase 2 and the regulation of human progesterone receptor activity
    • Moore NL, Narayanan R, Weigel NL. Cyclin dependent kinase 2 and the regulation of human progesterone receptor activity. Steroids. 2007; 72: 202-209.
    • (2007) Steroids , vol.72 , pp. 202-209
    • Moore, N.L.1    Narayanan, R.2    Weigel, N.L.3
  • 18
    • 0028606278 scopus 로고
    • Cyclin D1/cdk2 kinase is present in a G1 phase-specific protein complex Yi1 that binds to the mouse thymidine kinase gene promoter
    • Dou QP, Molnar G, Pardee AB. Cyclin D1/cdk2 kinase is present in a G1 phase-specific protein complex Yi1 that binds to the mouse thymidine kinase gene promoter. Biochem Biophys Res Commun. 1994; 205: 1859-1868.
    • (1994) Biochem Biophys Res Commun , vol.205 , pp. 1859-1868
    • Dou, Q.P.1    Molnar, G.2    Pardee, A.B.3
  • 19
    • 0027332123 scopus 로고
    • Altered regulation of G1 cyclins in senescent human diploid fibroblasts: Accumulation of inactive cyclin E-Cdk2 and cyclin D1-Cdk2 complexes
    • Dulić V, Drullinger LF, Lees E, Reed SI, Stein GH. Altered regulation of G1 cyclins in senescent human diploid fibroblasts: accumulation of inactive cyclin E-Cdk2 and cyclin D1-Cdk2 complexes. Proc Natl Acad Sci USA. 1993; 90: 11034-11038.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 11034-11038
    • Dulić, V.1    Drullinger, L.F.2    Lees, E.3    Reed, S.I.4    Stein, G.H.5
  • 20
    • 0032482437 scopus 로고    scopus 로고
    • Lack of relationship between CDK activity and G1 cyclin expression in breast cancer cells
    • Sweeney KJ, Swarbrick A, Sutherland RL, Musgrove EA. Lack of relationship between CDK activity and G1 cyclin expression in breast cancer cells. Oncogene. 1998; 16: 2865-2878.
    • (1998) Oncogene , vol.16 , pp. 2865-2878
    • Sweeney, K.J.1    Swarbrick, A.2    Sutherland, R.L.3    Musgrove, E.A.4
  • 21
    • 9144228160 scopus 로고    scopus 로고
    • Construction of a cyclin D1-Cdk2 fusion protein to model the biological functions of cyclin D1-Cdk2 complexes
    • Chytil A, Waltner-Law M, West R, et al. Construction of a cyclin D1-Cdk2 fusion protein to model the biological functions of cyclin D1-Cdk2 complexes. J Biol Chem. 2004; 279: 47688-47698.
    • (2004) J Biol Chem , vol.279 , pp. 47688-47698
    • Chytil, A.1    Waltner-Law, M.2    West, R.3
  • 22
    • 33846222825 scopus 로고    scopus 로고
    • Identification of cyclin D1-and estrogen-regulated genes contributing to breast carcinogenesis and progression
    • Yang C, Trent S, Ionescu-Tiba V, et al. Identification of cyclin D1-and estrogen-regulated genes contributing to breast carcinogenesis and progression. Cancer Res. 2006; 66: 11649-11658.
    • (2006) Cancer Res , vol.66 , pp. 11649-11658
    • Yang, C.1    Trent, S.2    Ionescu-Tiba, V.3
  • 23
    • 0042354669 scopus 로고    scopus 로고
    • A mechanism of cyclin D1 action encoded in the patterns of gene expression in human cancer
    • Lamb J, Ramaswamy S, Ford HL, et al. A mechanism of cyclin D1 action encoded in the patterns of gene expression in human cancer. Cell. 2003; 114: 323-334.
    • (2003) Cell , vol.114 , pp. 323-334
    • Lamb, J.1    Ramaswamy, S.2    Ford, H.L.3
  • 24
    • 9444236895 scopus 로고    scopus 로고
    • Minireview: Cyclin D1: Normal and abnormal functions
    • Fu M, Wang C, Li Z, Sakamaki T, Pestell RG. Minireview: Cyclin D1: normal and abnormal functions. Endocrinology. 2004; 145: 5439-5447.
    • (2004) Endocrinology , vol.145 , pp. 5439-5447
    • Fu, M.1    Wang, C.2    Li, Z.3    Sakamaki, T.4    Pestell, R.G.5
  • 25
    • 75149175161 scopus 로고    scopus 로고
    • Transcriptional role of cyclin D1 in development revealed by a genetic-proteomic screen
    • Bienvenu F, Jirawatnotai S, Elias JE, et al. Transcriptional role of cyclin D1 in development revealed by a genetic-proteomic screen. Nature. 2010; 463: 374-378.
    • (2010) Nature , vol.463 , pp. 374-378
    • Bienvenu, F.1    Jirawatnotai, S.2    Elias, J.E.3
  • 26
    • 41649119043 scopus 로고    scopus 로고
    • Progesterone receptor rapid signaling mediates serine 345 phosphorylation and tethering to specificity protein 1 transcription factors
    • Faivre EJ, Daniel AR, Hillard CJ, Lange CA. Progesterone receptor rapid signaling mediates serine 345 phosphorylation and tethering to specificity protein 1 transcription factors. Mol Endocrinol. 2008; 22: 823-837.
    • (2008) Mol Endocrinol , vol.22 , pp. 823-837
    • Faivre, E.J.1    Daniel, A.R.2    Hillard, C.J.3    Lange, C.A.4
  • 27
    • 0020026749 scopus 로고
    • Variant T47D human breast cancer cells with high progesterone-receptor levels despite estrogen and antiestrogen resistance
    • Horwitz KB, Mockus MB, Lessey BA. Variant T47D human breast cancer cells with high progesterone-receptor levels despite estrogen and antiestrogen resistance. Cell. 1982; 28: 633-642.
    • (1982) Cell , vol.28 , pp. 633-642
    • Horwitz, K.B.1    Mockus, M.B.2    Lessey, B.A.3
  • 28
    • 0028026693 scopus 로고
    • New T47D breast cancer cell lines for the independent study of progesterone B-and A-receptors: Only antiprogestin-occupied B-receptors are switched to transcriptional agonists by cAMP
    • Sartorius CA, Groshong SD, Miller LA, et al. New T47D breast cancer cell lines for the independent study of progesterone B-and A-receptors: only antiprogestin-occupied B-receptors are switched to transcriptional agonists by cAMP. Cancer Res. 1994; 54: 3868-3877.
    • (1994) Cancer Res , vol.54 , pp. 3868-3877
    • Sartorius, C.A.1    Groshong, S.D.2    Miller, L.A.3
  • 29
    • 10044257416 scopus 로고    scopus 로고
    • Phosphorylation of progesterone receptor serine 400 mediates ligand-independent transcriptional activity in response to activation of cyclin-dependent protein kinase 2
    • Pierson-Mullany LK, Lange CA. Phosphorylation of progesterone receptor serine 400 mediates ligand-independent transcriptional activity in response to activation of cyclin-dependent protein kinase 2. Mol Cell Biol. 2004; 24; 10542-10557.
    • (2004) Mol Cell Biol , vol.24 , pp. 10542-10557
    • Pierson-Mullany, L.K.1    Lange, C.A.2
  • 30
    • 79956122926 scopus 로고    scopus 로고
    • ck2-dependent phosphorylation of progesterone receptors (PR) on Ser81 regulates PR-B isoform-specific target gene expression in breast cancer cells
    • Hagan CR, Regan TM, Dressing GE, Lange CA. ck2-dependent phosphorylation of progesterone receptors (PR) on Ser81 regulates PR-B isoform-specific target gene expression in breast cancer cells. Mol Cell Biol. 2011; 31: 2439-2452.
    • (2011) Mol Cell Biol , vol.31 , pp. 2439-2452
    • Hagan, C.R.1    Regan, T.M.2    Dressing, G.E.3    Lange, C.A.4
  • 32
    • 10044257416 scopus 로고    scopus 로고
    • Phosphorylation of progesterone receptor serine 400 mediates ligand-independent transcriptional activity in response to activation of cyclin-dependent protein kinase 2
    • Pierson-Mullany LK, Lange CA. Phosphorylation of progesterone receptor serine 400 mediates ligand-independent transcriptional activity in response to activation of cyclin-dependent protein kinase 2. Mol Cell Biol. 2004; 24: 10542-10557.
    • (2004) Mol Cell Biol , vol.24 , pp. 10542-10557
    • Pierson-Mullany, L.K.1    Lange, C.A.2
  • 33
    • 33847081689 scopus 로고    scopus 로고
    • Cyclins, cyclin dependent kinases, and regulation of steroid receptor action
    • Weigel NL, Moore NL. Cyclins, cyclin dependent kinases, and regulation of steroid receptor action. Mol Cell Endocrinol. 2007; 265: 157-161.
    • (2007) Mol Cell Endocrinol , vol.265 , pp. 157-161
    • Weigel, N.L.1    Moore, N.L.2
  • 34
    • 79958703046 scopus 로고    scopus 로고
    • Regulation of progesterone receptor activity by cyclin dependent kinases 1 and 2 occurs in part by phosphorylation of the SRC-1 carboxyl-terminus
    • Moore NL, Weigel NL. Regulation of progesterone receptor activity by cyclin dependent kinases 1 and 2 occurs in part by phosphorylation of the SRC-1 carboxyl-terminus. Int J Biochem Cell Biol. 2011; 43: 1157-1167.
    • (2011) Int J Biochem Cell Biol , vol.43 , pp. 1157-1167
    • Moore, N.L.1    Weigel, N.L.2
  • 35
    • 0035896651 scopus 로고    scopus 로고
    • Identification of a phosphorylation site in the hinge region of the human progesterone receptor and additional amino-terminal phosphorylation sites
    • Knotts TA, Orkiszewski RS, Cook RG, Edwards DP, Weigel NL. Identification of a phosphorylation site in the hinge region of the human progesterone receptor and additional amino-terminal phosphorylation sites. J Biol Chem. 2001; 276: 8475-8483.
    • (2001) J Biol Chem , vol.276 , pp. 8475-8483
    • Knotts, T.A.1    Orkiszewski, R.S.2    Cook, R.G.3    Edwards, D.P.4    Weigel, N.L.5
  • 36
    • 0032553304 scopus 로고    scopus 로고
    • Convergence of progesterone and epidermal growth factor signaling in breast cancer. Potentiation of mitogen-activated protein kinase pathways
    • Lange CA, Richer JK, Shen T, Horwitz KB. Convergence of progesterone and epidermal growth factor signaling in breast cancer. Potentiation of mitogen-activated protein kinase pathways. J Biol Chem. 1998; 273: 31308-31316.
    • (1998) J Biol Chem , vol.273 , pp. 31308-31316
    • Lange, C.A.1    Richer, J.K.2    Shen, T.3    Horwitz, K.B.4
  • 37
    • 0037385535 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase regulates nuclear association of human progesterone receptors
    • Qiu M, Olsen A, Faivre E, Horwitz KB, Lange CA. Mitogen-activated protein kinase regulates nuclear association of human progesterone receptors. Mol Endocrinol. 2003; 17: 628-642.
    • (2003) Mol Endocrinol , vol.17 , pp. 628-642
    • Qiu, M.1    Olsen, A.2    Faivre, E.3    Horwitz, K.B.4    Lange, C.A.5
  • 38
    • 70149092341 scopus 로고    scopus 로고
    • Protein kinases mediate ligand-independent derepression of sumoylated progesterone receptors in breast cancer cells
    • Daniel AR, Lange CA. Protein kinases mediate ligand-independent derepression of sumoylated progesterone receptors in breast cancer cells. Proc Natl Acad Sci USA. 2009; 106: 14287-14292.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 14287-14292
    • Daniel, A.R.1    Lange, C.A.2
  • 39
    • 84863572365 scopus 로고    scopus 로고
    • Phosphorylated and sumoylation-deficient progesterone receptors drive proliferative gene signatures during breast cancer progression
    • Knutson TP, Daniel AR, Fan D, et al. Phosphorylated and sumoylation-deficient progesterone receptors drive proliferative gene signatures during breast cancer progression. Breast Cancer Res. 2012; 14: R95.
    • (2012) Breast Cancer Res , vol.14
    • Knutson, T.P.1    Daniel, A.R.2    Fan, D.3
  • 40
    • 0038054341 scopus 로고    scopus 로고
    • PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
    • Mootha VK, Lindgren CM, Eriksson KF, et al. PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet. 2003; 34: 267-273.
    • (2003) Nat Genet , vol.34 , pp. 267-273
    • Mootha, V.K.1    Lindgren, C.M.2    Eriksson, K.F.3
  • 41
    • 27344435774 scopus 로고    scopus 로고
    • Gene set enrichment analysis: A knowledge-based approach for interpreting genomewide expression profiles
    • Subramanian A, Tamayo P, Mootha VK, et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genomewide expression profiles. Proc Natl Acad Sci USA. 2005; 102: 15545-15550.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 15545-15550
    • Subramanian, A.1    Tamayo, P.2    Mootha, V.K.3
  • 42
    • 44849114353 scopus 로고    scopus 로고
    • Subtypes of breast cancer show preferential site of relapse
    • Smid M, Wang Y, Zhang Y, et al. Subtypes of breast cancer show preferential site of relapse. Cancer Res. 2008; 68: 3108-3114.
    • (2008) Cancer Res , vol.68 , pp. 3108-3114
    • Smid, M.1    Wang, Y.2    Zhang, Y.3
  • 43
    • 23444434936 scopus 로고    scopus 로고
    • Gene expression profiling of cancer progression reveals intrinsic regulation of transforming growth factor-β signaling in ErbB2/Neu-induced tumors from transgenic mice
    • Landis MD, Seachrist DD, Montañez-Wiscovich ME, Danielpour D, Keri RA. Gene expression profiling of cancer progression reveals intrinsic regulation of transforming growth factor-β signaling in ErbB2/Neu-induced tumors from transgenic mice. Oncogene. 2005; 24: 5173-5190.
    • (2005) Oncogene , vol.24 , pp. 5173-5190
    • Landis, M.D.1    Seachrist, D.D.2    Montañez-Wiscovich, M.E.3    Danielpour, D.4    Keri, R.A.5
  • 44
    • 33745603978 scopus 로고    scopus 로고
    • An estrogen receptor-negative breast cancer subset characterized by a hormonally regulated transcriptional program and response to androgen
    • Doane AS, Danso M, Lal P, et al. An estrogen receptor-negative breast cancer subset characterized by a hormonally regulated transcriptional program and response to androgen. Oncogene. 2006; 25: 3994-4008.
    • (2006) Oncogene , vol.25 , pp. 3994-4008
    • Doane, A.S.1    Danso, M.2    Lal, P.3
  • 45
    • 84866002291 scopus 로고    scopus 로고
    • The cBio cancer genomics portal: An open platform for exploring multidimensional cancer genomics data
    • Cerami E, Gao J, Dogrusoz U, et al. The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data. Cancer Discov. 2012; 2: 401-404.
    • (2012) Cancer Discov , vol.2 , pp. 401-404
    • Cerami, E.1    Gao, J.2    Dogrusoz, U.3
  • 46
    • 84875740314 scopus 로고    scopus 로고
    • Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal
    • Gao J, Aksoy BA, Dogrusoz U, et al. Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal. Sci Signal. 2013; 6: pl1.
    • (2013) Sci Signal , vol.6
    • Gao, J.1    Aksoy, B.A.2    Dogrusoz, U.3
  • 47
    • 79952128110 scopus 로고    scopus 로고
    • High-throughput ectopic expression screen for tamoxifen resistance identifies an atypical kinase that blocks autophagy
    • Gonzalez-Malerva L, Park J, Zou L, et al. High-throughput ectopic expression screen for tamoxifen resistance identifies an atypical kinase that blocks autophagy. Proc Natl Acad Sci USA. 2011; 108: 2058-2063.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 2058-2063
    • Gonzalez-Malerva, L.1    Park, J.2    Zou, L.3
  • 48
    • 84880268260 scopus 로고    scopus 로고
    • LMTK3 is implicated in endocrine resistance via multiple signaling pathways
    • Stebbing J, Filipovic A, Lit LC, et al. LMTK3 is implicated in endocrine resistance via multiple signaling pathways. Oncogene. 2013; 32: 3371-3380.
    • (2013) Oncogene , vol.32 , pp. 3371-3380
    • Stebbing, J.1    Filipovic, A.2    Lit, L.C.3
  • 49
    • 0034212762 scopus 로고    scopus 로고
    • Interaction between Sp1 and cell cycle regulatory proteins is important in transactivation of a differentiationrelated gene
    • Opitz OG, Rustgi AK. Interaction between Sp1 and cell cycle regulatory proteins is important in transactivation of a differentiationrelated gene. Cancer Res. 2000; 60: 2825-2830.
    • (2000) Cancer Res , vol.60 , pp. 2825-2830
    • Opitz, O.G.1    Rustgi, A.K.2
  • 50
    • 84865574311 scopus 로고    scopus 로고
    • Transcriptional regulation by post-transcriptional modification-Role of phosphorylation in Sp1 transcriptional activity
    • Chu S. Transcriptional regulation by post-transcriptional modification-Role of phosphorylation in Sp1 transcriptional activity. Gene. 2012; 508: 1-8.
    • (2012) Gene , vol.508 , pp. 1-8
    • Chu, S.1
  • 51
    • 81155123653 scopus 로고    scopus 로고
    • A comprehensive view of nuclear receptor cancer cistromes
    • Tang Q, Chen Y, Meyer C, et al. A comprehensive view of nuclear receptor cancer cistromes. Cancer Res. 2011; 71: 6940-6947.
    • (2011) Cancer Res , vol.71 , pp. 6940-6947
    • Tang, Q.1    Chen, Y.2    Meyer, C.3
  • 54
    • 84865839222 scopus 로고    scopus 로고
    • CDK2-dependent activation of PARP-1 is required for hormonal gene regulation in breast cancer cells
    • Wright RH, Castellano G, Bonet J, et al. CDK2-dependent activation of PARP-1 is required for hormonal gene regulation in breast cancer cells. Genes Dev. 2012; 26: 1972-1983.
    • (2012) Genes Dev , vol.26 , pp. 1972-1983
    • Wright, R.H.1    Castellano, G.2    Bonet, J.3
  • 55
    • 36849096094 scopus 로고    scopus 로고
    • Phosphorylation-dependent antagonism of sumoylation derepresses progesterone receptor action in breast cancer cells
    • Daniel AR, Faivre EJ, Lange CA. Phosphorylation-dependent antagonism of sumoylation derepresses progesterone receptor action in breast cancer cells. Mol Endocrinol. 2007; 21: 2890-2906.
    • (2007) Mol Endocrinol , vol.21 , pp. 2890-2906
    • Daniel, A.R.1    Faivre, E.J.2    Lange, C.A.3
  • 56
    • 63649127559 scopus 로고    scopus 로고
    • Integrated actions of progesterone receptor and cell cycle machinery regulate breast cancer cell proliferation
    • Dressing GE, Lange CA. Integrated actions of progesterone receptor and cell cycle machinery regulate breast cancer cell proliferation. Steroids. 2009; 74: 573-576.
    • (2009) Steroids , vol.74 , pp. 573-576
    • Dressing, G.E.1    Lange, C.A.2
  • 57
    • 0026080046 scopus 로고
    • Immunocytochemical localization of casein kinase II during interphase and mitosis
    • Yu IJ, Spector DL, Bae YS, Marshak DR. Immunocytochemical localization of casein kinase II during interphase and mitosis. J Cell Biol. 1991; 114: 1217-1232.
    • (1991) J Cell Biol , vol.114 , pp. 1217-1232
    • Yu, I.J.1    Spector, D.L.2    Bae, Y.S.3    Marshak, D.R.4
  • 60
    • 69249230769 scopus 로고    scopus 로고
    • Mammalian cell-cycle regulation: Several Cdks, numerous cyclins and diverse compensatory mechanisms
    • Satyanarayana A, Kaldis P. Mammalian cell-cycle regulation: several Cdks, numerous cyclins and diverse compensatory mechanisms. Oncogene. 2009; 28: 2925-2939.
    • (2009) Oncogene , vol.28 , pp. 2925-2939
    • Satyanarayana, A.1    Kaldis, P.2
  • 61
    • 28244486944 scopus 로고    scopus 로고
    • Progestin activation of nongenomic pathways via cross talk of progesterone receptor with estrogen receptor β induces proliferation of endometrial stromal cells
    • Vallejo G, Ballaré C, Barañao JL, Beato M, Saragüeta P. Progestin activation of nongenomic pathways via cross talk of progesterone receptor with estrogen receptor β induces proliferation of endometrial stromal cells. Mol Endocrinol. 2005; 19: 3023-3037.
    • (2005) Mol Endocrinol , vol.19 , pp. 3023-3037
    • Vallejo, G.1    Ballaré, C.2    Barañao, J.L.3    Beato, M.4    Saragüeta, P.5
  • 62
    • 34250883219 scopus 로고    scopus 로고
    • Progestin effects on breast cancer cell proliferation, proteases activation, and in vivo development of metastatic phenotype all depend on progesterone receptor capacity to activate cytoplasmic signaling pathways
    • Carnevale RP, Proietti CJ, Salatino M, et al. Progestin effects on breast cancer cell proliferation, proteases activation, and in vivo development of metastatic phenotype all depend on progesterone receptor capacity to activate cytoplasmic signaling pathways. Mol Endocrinol. 2007; 21: 1335-1358.
    • (2007) Mol Endocrinol , vol.21 , pp. 1335-1358
    • Carnevale, R.P.1    Proietti, C.J.2    Salatino, M.3
  • 63
    • 16244382046 scopus 로고    scopus 로고
    • Human progesterone receptor displays cell cycle-dependent changes in transcriptional activity
    • Narayanan R, Edwards DP, Weigel NL. Human progesterone receptor displays cell cycle-dependent changes in transcriptional activity. Mol Cell Biol. 2005; 25: 2885-2898.
    • (2005) Mol Cell Biol , vol.25 , pp. 2885-2898
    • Narayanan, R.1    Edwards, D.P.2    Weigel, N.L.3
  • 64
    • 77953383265 scopus 로고    scopus 로고
    • Cyclin D1 enhances the response to estrogen and progesterone by regulating progesterone receptor expression
    • Yang C, Chen L, Li C, Lynch MC, Brisken C, Schmidt EV. Cyclin D1 enhances the response to estrogen and progesterone by regulating progesterone receptor expression. Mol Cell Biol. 2010; 30: 3111-3125.
    • (2010) Mol Cell Biol , vol.30 , pp. 3111-3125
    • Yang, C.1    Chen, L.2    Li, C.3    Lynch, M.C.4    Brisken, C.5    Schmidt, E.V.6
  • 65
    • 78649740898 scopus 로고    scopus 로고
    • Progesterone receptor induces ErbB-2 nuclear translocation to promote breast cancer growth via a novel transcriptional effect: ErbB-2 function as a coactivator of Stat3
    • Béguelin W, Díaz Flaqué MC, Proietti CJ, et al. Progesterone receptor induces ErbB-2 nuclear translocation to promote breast cancer growth via a novel transcriptional effect: ErbB-2 function as a coactivator of Stat3. Mol Cell Biol. 2010; 30: 5456-5472.
    • (2010) Mol Cell Biol , vol.30 , pp. 5456-5472
    • Béguelin, W.1    Díaz Flaqué, M.C.2    Proietti, C.J.3
  • 66
    • 0037121081 scopus 로고    scopus 로고
    • Linking cyclins to transcriptional control
    • Coqueret O. Linking cyclins to transcriptional control. Gene. 2002; 299: 35-55.
    • (2002) Gene , vol.299 , pp. 35-55
    • Coqueret, O.1
  • 67
    • 84863256545 scopus 로고    scopus 로고
    • ChIP sequencing of cyclin D1 reveals a transcriptional role in chromosomal instability in mice
    • Casimiro MC, Crosariol M, Loro E, et al. ChIP sequencing of cyclin D1 reveals a transcriptional role in chromosomal instability in mice. J Clin Invest. 2012; 122: 833-843.
    • (2012) J Clin Invest , vol.122 , pp. 833-843
    • Casimiro, M.C.1    Crosariol, M.2    Loro, E.3
  • 68
    • 77049121544 scopus 로고    scopus 로고
    • Analysis of cyclins A, B1, D1 and E in breast cancer in relation to tumour grade and other prognostic factors
    • Bostrom P, Söderström M, Palokangas T, et al. Analysis of cyclins A, B1, D1 and E in breast cancer in relation to tumour grade and other prognostic factors. BMC Res Notes. 2009; 2: 140.
    • (2009) BMC Res Notes , vol.2 , pp. 140
    • Bostrom, P.1    Söderström, M.2    Palokangas, T.3
  • 69
    • 74549136917 scopus 로고    scopus 로고
    • Cyclin D1b represses breast cancer cell growth by antagonizing the action of cyclin D1a on estrogen receptor α-mediated transcription
    • Zhu J, Sen S, Wei C, Frazier ML. Cyclin D1b represses breast cancer cell growth by antagonizing the action of cyclin D1a on estrogen receptor α-mediated transcription. Int J Oncol. 2010; 36: 39-48.
    • (2010) Int J Oncol , vol.36 , pp. 39-48
    • Zhu, J.1    Sen, S.2    Wei, C.3    Frazier, M.L.4
  • 70
    • 0037047269 scopus 로고    scopus 로고
    • Cyclin D1 is a ligand-independent co-repressor for thyroid hormone receptors
    • Lin HM, Zhao L, Cheng SY. Cyclin D1 is a ligand-independent co-repressor for thyroid hormone receptors. J Biol Chem. 2002; 277: 28733-28741.
    • (2002) J Biol Chem , vol.277 , pp. 28733-28741
    • Lin, H.M.1    Zhao, L.2    Cheng, S.Y.3
  • 71
    • 67649669246 scopus 로고    scopus 로고
    • DNA replication licensing and progenitor numbers are increased by progesterone in normal human breast
    • Graham JD, Mote PA, Salagame U, et al. DNA replication licensing and progenitor numbers are increased by progesterone in normal human breast. Endocrinology. 2009; 150: 3318-3326.
    • (2009) Endocrinology , vol.150 , pp. 3318-3326
    • Graham, J.D.1    Mote, P.A.2    Salagame, U.3
  • 72
    • 84877028141 scopus 로고    scopus 로고
    • Comprehensive molecular portraits of human breast tumours
    • Cancer Genome Atlas Network
    • Cancer Genome Atlas Network. Comprehensive molecular portraits of human breast tumours. Nature. 2012; 490: 61-70.
    • (2012) Nature , vol.490 , pp. 61-70
  • 74
    • 78650208471 scopus 로고    scopus 로고
    • Amphiregulin mediates estrogen, progesterone, and EGFR signaling in the normal rat mammary gland and in hormone-dependent rat mammary cancers
    • Kariagina A, Xie J, Leipprandt JR, Haslam SZ. Amphiregulin mediates estrogen, progesterone, and EGFR signaling in the normal rat mammary gland and in hormone-dependent rat mammary cancers. Horm Cancer. 2010; 1: 229-244.
    • (2010) Horm Cancer , vol.1 , pp. 229-244
    • Kariagina, A.1    Xie, J.2    Leipprandt, J.R.3    Haslam, S.Z.4
  • 75
    • 84884716519 scopus 로고    scopus 로고
    • Randomized phase II study of lonaprisan as second-line therapy for progesterone receptor-positive breast cancer
    • Jonat W, Bachelot T, Ruhstaller T, Kuss I, Reimann U, Robertson JF. Randomized phase II study of lonaprisan as second-line therapy for progesterone receptor-positive breast cancer. Ann Oncol. 2013; 24: 2543-2548.
    • (2013) Ann Oncol , vol.24 , pp. 2543-2548
    • Jonat, W.1    Bachelot, T.2    Ruhstaller, T.3    Kuss, I.4    Reimann, U.5    Robertson, J.F.6
  • 78
    • 0029113686 scopus 로고
    • Changes in estrogen receptor, progesterone receptor, and pS2 expression in tamoxifenresistant human breast cancer
    • Johnston SR, Saccani-Jotti G, Smith IE, et al. Changes in estrogen receptor, progesterone receptor, and pS2 expression in tamoxifenresistant human breast cancer. Cancer Res. 1995; 55: 3331-3338.
    • (1995) Cancer Res , vol.55 , pp. 3331-3338
    • Johnston, S.R.1    Saccani-Jotti, G.2    Smith, I.E.3
  • 80
    • 69249137029 scopus 로고    scopus 로고
    • Biological determinants of endocrine resistance in breast cancer
    • Musgrove EA, Sutherland RL. Biological determinants of endocrine resistance in breast cancer. Nat Rev Cancer. 2009; 9: 631-643.
    • (2009) Nat Rev Cancer , vol.9 , pp. 631-643
    • Musgrove, E.A.1    Sutherland, R.L.2
  • 81
    • 2942533005 scopus 로고    scopus 로고
    • Cyclin D1 overexpression is a negative predictive factor for tamoxifen response in postmenopausal breast cancer patients
    • Stendahl M, Kronblad A, Rydén L, Emdin S, Bengtsson NO, Landberg G. Cyclin D1 overexpression is a negative predictive factor for tamoxifen response in postmenopausal breast cancer patients. Br J Cancer. 2004; 90: 1942-1948.
    • (2004) Br J Cancer , vol.90 , pp. 1942-1948
    • Stendahl, M.1    Kronblad, A.2    Rydén, L.3    Emdin, S.4    Bengtsson, N.O.5    Landberg, G.6
  • 82
    • 0035726623 scopus 로고    scopus 로고
    • Transcriptional hyperactivity of human progesterone receptors is coupled to their ligand-dependent down-regulation by mitogen-activated protein kinase-dependent phosphorylation of serine 294
    • Shen T, Horwitz KB, Lange CA. Transcriptional hyperactivity of human progesterone receptors is coupled to their ligand-dependent down-regulation by mitogen-activated protein kinase-dependent phosphorylation of serine 294. Mol Cell Biol. 2001; 21: 6122-6131.
    • (2001) Mol Cell Biol , vol.21 , pp. 6122-6131
    • Shen, T.1    Horwitz, K.B.2    Lange, C.A.3
  • 83
    • 0033967491 scopus 로고    scopus 로고
    • Phosphorylation of human progesterone receptors at serine-294 by mitogen-activated protein kinase signals their degradation by the 26S proteasome
    • Lange CA, Shen T, Horwitz KB. Phosphorylation of human progesterone receptors at serine-294 by mitogen-activated protein kinase signals their degradation by the 26S proteasome. Proc Natl Acad Sci USA. 2000; 97: 1032-1037.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 1032-1037
    • Lange, C.A.1    Shen, T.2    Horwitz, K.B.3


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