Integrated actions of progesterone receptor and cell cycle machinery regulate breast cancer cell proliferation

Steroids

Volumn 74, Issue 7, 2009, Pages 573-576

  Dressing, Gwen E ^a   Lange, Carol A ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Cell cycle; Cyclin D; Cyclin dependent kinase 2; p21; p27; Progesterone receptor

Indexed keywords

CYCLIN D; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLIN E; CYCLINE; ESTROGEN RECEPTOR; PROGESTERONE RECEPTOR; STEROID RECEPTOR;

ARTICLE; BREAST CANCER; CELL CYCLE PROGRESSION; CELL CYCLE REGULATION; CELL PROLIFERATION; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION;

ANIMALS; BREAST NEOPLASMS; CELL CYCLE; CELL PROLIFERATION; HUMANS; RECEPTORS, PROGESTERONE; SIGNAL TRANSDUCTION;

EID: 63649127559     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.steroids.2008.12.001     Document Type: Article

References (40)

1. Groshong S.D., Owen G.I., Grimison B., Schauer I.E., Todd M.C., Langan T.A., et al. Biphasic regulation of breast cancer cell growth by progesterone: role of the cyclin-dependent kinase inhibitors, p21 and p27 (Kip1). Molecular Endocrinology 11 (1997) 1593-1607
2. Lange C.A. Making sense of cross-talk between steroid hormone receptors and intracellular signaling pathways: who will have the last word?. Molecular Endocrinology 18 (2004) 269-278
3. Lange C.A., Richer J.K., and Horwitz K.B. Hypothesis: progesterone primes breast cancer cells for cross-talk with proliferative or antiproliferative signals. Molecular Endocrinology 13 (1999) 829-836
4. Lange C.A., Richer J.K., Shen T., and Horwitz K.B. Convergence of progesterone and epidermal growth factor signaling in breast cancer. Potentiation of mitogen-activated protein kinase pathways. The Journal of Biological Chemistry 273 (1998) 31308-31316
5. Musgrove E.A., Hamilton J.A., Lee C.S.L., Sweeney K.J.E., Watts C.K.W., and Sutherland R.L. Growth factor, steroid, and steroid antagonist regulation of cyclin gene expression associated with changes in T-47D human breast cancer cell cycle progression. Molecular and Cellular Biology 13 (1993) 3577-3587
6. Reis-Fihlo J.S., Savage K., Lambros M., James M., Steele D., Jones R., et al. Cyclin D1 protein overexpression and CCND1 amplification in breast carcinomas: an immunohistochemical and chromogenic in situ hybridisation analysis. Modern Pathology 19 (2006) 999-1009
7. KIP-1 correlates with hormone receptor status but not with local recurrence. Pathology International 57 (2007) 183-189
8. Hui R., Cornish A.L., McClelland R.A., Roberson J.F., Blamey R.W., Musgrove E.A., et al. Cyclin D1 and estrogen receptor messenger RNA levels are positively correlated in primary breast cancer. Clinical Cancer Research 2 (1996) 923-928
9. Al-Kuraya K., Schraml P., Torhorst J., Tapia C., Zaharieva B., Novotny H., et al. Prognostic relevance of gene amplifications and coamplifications in breast cancer. Cancer Research 64 (2004) 8534-8540
10. Sicinski P., Donaher J.P., Parker S.B., Li T., Fazeli A., Gardner H., et al. Cyclin D1 provides a link between development and oncogenesis in the retina and breast. Cell 82 (1995) 621-630
11. Mulac-Jericevic B., Lydon J.P., DeMayo F.J., and Conneely O.M. Defective mammary gland morphogeneis in mice lacking the progesterone receptor B isoform. Proceeding of the National Academy of Sciences 100 (2003) 9744-9749
12. Zwijzen R.M., Buckle R.S., Hijmans E.M., Loomans C.J., and Bernards R. Ligand-independent recruitment of steroid receptor coactivators to estrogen receptor by cyclin D1. Genes and Development 12 (1998) 3488-3498
13. McMahon C., Suthiphongchai T., DiRenzo J., and Ewen M.E. P/CAF associates with cyclin D1 and potentiates its activation of the estrogen receptor. Proceeding of the National Academy of Sciences 96 (1999) 5382-5387
14. Knudsen K.E., Cavenee W.K., and Arden K.C. D-type cyclins complex with the androgen receptor and inhibit its transcriptional transactivation ability. Cancer Research 59 (1999) 2297-2301
15. Reutens A.T., Fu M., Wang C., Albanese C., McPhaul M.J., Sun Z., et al. Cyclin D1 binds the androgen receptor and regulates hormone-dependent signaling in a p300/CBP-associated factor (P/CAF)-dependent manner. Molecular Endocrinology 15 (2001) 797-811
16. Petre C.E., Wetherill Y.B., Danielsen M., and Knudsen K.E. Cyclin D1: mechanism and consequence of androgen receptor co-repressor activity. The Journal of Biological Chemistry 277 (2002) 2207-2215
17. Petre-Draviam C.E., Cook S.L., Burd C.J., Marshall T.W., Wetherill Y.B., and Knudsen K.E. Specificity of cyclin D1 for androgen receptor regulation. Cancer Research 63 (2003) 4903-4913
18. Burd C.J., Petre C.E., Moghadam H., Wilson E.M., and Knudsen K.E. Cyclin D1 binding to the androgen receptor (AR) NH2-terminal domain inhibits activation of function 2 association and reveals dual roles for AR corepression. Molecular Endocrinology 19 (2005) 607-620
19. Petre-Draviam C.E., Williams E.B., Burd C.J., Gladden A., Moghadam H., Meller J., et al. A central domain of cyclin D1 mediates nuclear receptor corepressor activity. Oncogene 24 (2005) 431-444
20. Burd C.J., Petre C.E., Morney L.M., Wang Y.L., Revelo M.P., Haiman C.A., et al. Cyclin D1b variant influences prostate cancer growth through aberrant androgen receptor regulation. Proceeding of the National Academy of Sciences 103 (2006) 2190-2195
21. Lin H.M., Zhao L., and Cheng S.Y. Cyclin D1 is a ligand-independent co-repressor for thyroid hormone receptors. The Journal of Biological Chemistry 277 (2002) 28733-28741
22. Faivre E., and Lange C.A. Progesterone receptors upregulate Wnt-1 to induce epidermal growth factor receptor transactivation and c-Src-dependent sustained activation of Erk1/2 mitogen-activated protein kinase in breast cancer cells. Molecular and Cellular Biology 27 (2007) 466-480
23. McGowan E.M., Russell A.J., Boonyaratanakornkit V., Saunders D.N., Lehrbach G.M., Sergio C.M., et al. Progestins reinitiate cell cycle progression in antiestrogen-arrested breast cancer cells through the B-isoform of progesterone receptor. Cancer Research 67 (2007) 8942-8951
24. 2 phase. Oncogene 21 (2002) 7545-7556
25. Rosenwald I.B., Kaspar R., Rousseau D., Gehrke L., Leboulch P., Chen J.J., et al. Eukaryotic translation initiation factor 4E regulates expression of cyclin D1 at transcriptional and post-transcriptional levels. The Journal of Biological Chemistry 270 (1995) 21176-21180
26. Swarbrick A., Lee C.S.L., Sutherland R.L., and Musgrove E.A. Cooperation of p27/kip and p18/INK4c in progestin-mediated cell cycle arrest in T-47D breast cancer cells. Molecular and Cellular Biology 20 (2000) 2581-2591
27. Musgrove E.A., Swarbrick A., Lee C.S.L., Cornish A.L., and Sutherland R.L. Mechanisms of cyclin-dependent kinase inactivation by progestins. Molecular and Cellular Biology 18 (1998) 1812-1825
28. Kip1 association with cyclin E-Cdk2. The Journal of Biological Chemistry 276 (2001) 47675-47683
29. LaBaer J., Garrett M.D., Stevenson L.F., Slingerland J.M., Sandhu C., Chou H.S., et al. New functional activities for the p21 family of CDK inhibitors. Genes & Development 11 (1997) 847-862
30. Weigel N.L. Steroid hormone receptors and their regulation by phosphorylation. Biochemical Journal 319 (1996) 657-667
31. Weigel N.L., Bai W., Zhang Y., Beck C.A., Edwards D.P., and Poletti A. Phosphorylation and progesterone receptor function. Journal of Steroid Biochemistry and Molecular Biology 53 (1995) 509-514
32. Moore N.L., Narayanan R., and Weigel N.L. Cyclin dependent kinase 2 and the regulation of human progesterone receptor activity. Steroids 72 (2007) 202-209
33. Galliher-Beckley A.J., Williams J.G., Collins J.B., and Cidlowski J.A. GSK-3{beta}-mediated serine phosphorylation of the human glucocorticoid receptor re-directs gene expression profiles. Molecular Cellular Biology (2008)
34. Chen W., Dang T., Blind R.D., Wang Z., Cavasotto C.N., Hittelman A.B., et al. Glucocorticoid receptor phosphorylation differentially affects target gene expression. Molecular Endocrinology 22 (2008) 1754-1766
35. Daniel A., Qiu M., Faivre E., Ostrander J., Skildum A., and Lange C. Linkage of progestin and epidermal growth factor signaling: phosphorylation of progesterone receptors mediates transcriptional hypersensitivity and increased ligand-independent breast cancer cell growth. Steroids 72 (2007) 188-201
36. Pierson-Mullany L.K., and Lange C.A. Phosphorylation of progesterone receptor serine 400 mediates ligand-independent transcriptional activity in response to activation of cyclin-dependent protein kinase 2. Molecular and Cellular Biology 24 (2004) 10542-10557
37. Narayanan R., Adigun A.A., Edwards D.P., and Weigel N.L. Cyclin-dependent kinase activity is required for progesterone receptor function: novel role for cyclin A/Cdk2 as a progesterone receptor coactivator. Molecular and Cellular Biology 25 (2005) 264-277
38. Faivre E.J., Daniel A.R., Hillard C.J., and Lange C.A. Progesterone receptor rapid signaling mediates Ser345 phosphorylation and tethering to Sp1 transcription factors. Molecular Endocrinology (2008)
39. Owen G.I., Richer J.K., Tung L., Takimoto G., and Horwitz K.B. Progesterone regulates transcription of the p21(WAF1) cyclin-dependent kinase inhibitor gene through Sp1 and CBP/p300. The Journal of Biological Chemistry 273 (1998) 10696-10701
40. Narayanan R., Edwards D.P., and Weigel N.L. Human progesterone receptor displays cell cycle-dependent changes in transcriptional activity. Molecular and Cellular Biochemistry 25 (2005) 2885-2898