Re-engineering the μ-conotoxin SIIIA scaffold

Biopolymers

Volumn 101, Issue 4, 2014, Pages 347-354

  Akondi, K B ^a   Lewis, R J ^a   Alewood, P F ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Nmr Spectroscopy; Peptides; Peptidomimetics; Spps; Structure Activity Relationships; Voltage Gated Sodium Channels; Conotoxin; Siiia

Indexed keywords

ELECTROPHYSIOLOGY; MAMMALS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PEPTIDES;

CONOTOXINS; PEPTIDOMIMETICS; SODIUM CHANNEL; SPPS; STRUCTURE ACTIVITY RELATIONSHIPS;

SCAFFOLDS;

ANALGESIC AGENT; OMEGA CONOTOXIN SIIIA; SODIUM CHANNEL BLOCKING AGENT; SODIUM CHANNEL NAV1.2; UNCLASSIFIED DRUG; CONOTOXIN; MUTANT PROTEIN;

ACTION POTENTIAL; ANALGESIC ACTIVITY; ARTICLE; DRUG POTENCY; DRUG SYNTHESIS; NUCLEAR MAGNETIC RESONANCE; PHARMACOPHORE; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM; MOLECULAR GENETICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN ENGINEERING; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; REVERSED PHASE LIQUID CHROMATOGRAPHY; TISSUE SCAFFOLD; WISTAR RAT;

AMINO ACID SEQUENCE; ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, REVERSE-PHASE; CONOTOXINS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; NAV1.2 VOLTAGE-GATED SODIUM CHANNEL; PROTEIN ENGINEERING; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; RATS, WISTAR; TISSUE SCAFFOLDS;

EID: 84897735499     PISSN: 00063525     EISSN: 10970282     Source Type: Journal    
DOI: 10.1002/bip.22368     Document Type: Article

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