Functionalized scaffolds to control dental pulp stem cell fate

Journal of Endodontics

Volumn 40, Issue 4 SUPPL., 2014, Pages

  Piva, Evandro ^a,b   Silva, Adriana F ^a,b   Nör, Jacques E ^b,c,d  

^a FEDERAL UNIVERSITY OF PELOTAS   (Brazil)

^b UNIVERSITY OF MICHIGAN SCHOOL OF DENTISTRY   (United States)

^c The Department of Civil and Environmental Engineering   (United States)

^d UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Angiogenesis; dental pulp stem cells; dentin; morphogenic signals; pulp biology; regenerative endodontics; tissue engineering

Indexed keywords

ANGIOGENIC PROTEIN; PROTEIN;

CELL DIFFERENTIATION; CYTOLOGY; DENTIN; HUMAN; MULTIPOTENT STEM CELL; ODONTOBLAST; PHYSIOLOGY; PROCEDURES; SIGNAL TRANSDUCTION; STEM CELL; TISSUE ENGINEERING; TISSUE SCAFFOLD; TOOTH PULP;

ANGIOGENIC PROTEINS; CELL DIFFERENTIATION; DENTAL PULP; DENTIN; HUMANS; MULTIPOTENT STEM CELLS; ODONTOBLASTS; PROTEINS; SIGNAL TRANSDUCTION; STEM CELLS; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 84897550040     PISSN: 00992399     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joen.2014.01.013     Document Type: Article

References (109)

1. R. Langer, and J.P. Vacanti Tissue engineering Science 260 1993 920 926
2. S. Yang, K.F. Leong, and Z. Du et al. The design of scaffolds for use in tissue engineering. Part I. Traditional factors Tissue Eng 7 2001 679 689
3. E. Lavik, and R. Langer Tissue engineering: current state and perspectives Appl Microbiol Biotechnol 65 2004 1 8
4. M.H. Sheridan, L.D. Shea, and M.C. Peters et al. Bioabsorbable polymer scaffolds for tissue engineering capable of sustained growth factor delivery J Control Release 64 2000 91 102
5. J.S. Golub, Y.T. Kim, and C.L. Duvall et al. Sustained VEGF delivery via PLGA nanoparticles promotes vascular growth Am J Physiol 298 2010 H1959 H1965
6. S. Fujiwara, S. Kumabe, and Y. Iwai Isolated rat dental pulp cell culture and transplantation with an alginate scaffold Okajimas Folia Anat Jpn 83 2006 15 24
7. K.S. Bohl, J. Shon, and B. Rutherford et al. Role of synthetic extracellular matrix in development of engineered dental pulp J Biomater Sci Polym Ed 9 1998 749 764
8. A. Moshaverinia, C. Chen, and K. Akiyama et al. Alginate hydrogel as a promising scaffold for dental-derived stem cells: an in vitro study J Mater Sci Mater Med 23 2012 3041 3051
9. A. Moshaverinia, S. Ansari, and C. Chen et al. Co-encapsulation of anti-BMP2 monoclonal antibody and mesenchymal stem cells in alginate microspheres for bone tissue engineering Biomaterials 34 2013 6572 6579
10. A.J. Smith, and H. Lesot Induction and regulation of crown dentinogenesis: embryonic events as a template for dental tissue repair? Crit Rev Oral Biol Med 12 2001 425 437
11. L.V. Keller, S. Kuchler-Bopp, and H. Lesot Restoring physiological cell heterogeneity in the mesenchyme during tooth engineering Int J Dev Biol 56 2012 737 746
12. A. Nait Lechguer, M.L. Couble, and N. Labert et al. Cell differentiation and matrix organization in engineered teeth J Dent Res 90 2011 583 589
13. I. Thesleff, and P. Sharpe Signalling networks regulating dental development Mech Dev 67 1997 111 123
14. Y. Chai, and H.C. Slavkin Prospects for tooth regeneration in the 21st century: a perspective Microsc Res Tech 60 2003 469 479
15. P.T. Sharpe, and C.S. Young Test-tube teeth Sci Am 293 2005 34 41
16. T. Sreenath, T. Thyagarajan, and B. Hall et al. Dentin sialophosphoprotein knockout mouse teeth display widened predentin zone and develop defective dentin mineralization similar to human dentinogenesis imperfecta type III J Biol Chem 278 2003 24874 24880
17. Y. Sun, Y. Lu, and L. Chen et al. DMP1 processing is essential to dentin and jaw formation J Dent Res 90 2011 619 624
18. R. Maas, and M. Bei The genetic control of early tooth development Crit Rev Oral Biol Med 8 1997 4 39
19. Y. Chen, M. Bei, and I. Woo et al. Msx1 controls inductive signaling in mammalian tooth morphogenesis Development 122 1996 3035 3044
20. C.W. Gibson, Z.A. Yuan, and B. Hall et al. Amelogenin-deficient mice display an amelogenesis imperfecta phenotype J Biol Chem 276 2001 31871 31875
21. M. Zeichner-David, T. Diekwisch, and A. Fincham et al. Control of ameloblast differentiation Int J Dev Biol 39 1995 69 92
22. D.J. Chiego Jr., J.K. Avery, and R.M. Klein Neuroregulation of protein synthesis in odontoblasts of the first molar of the rat after wounding Cell Tissue Res 248 1987 119 123
23. D. Tziafas, A.J. Smith, and H. Lesot Designing new treatment strategies in vital pulp therapy J Dent 28 2000 77 92
24. M. Fitzgerald, D.J. Chiego Jr., and D.R. Heys Autoradiographic analysis of odontoblast replacement following pulp exposure in primate teeth Arch Oral Biol 35 1990 707 715
25. S. Gronthos, M. Mankani, and J. Brahim et al. Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo Proc Natl Acad Sci U S A 97 2000 13625 13630
26. M. Miura, S. Gronthos, and M. Zhao et al. SHED: stem cells from human exfoliated deciduous teeth Proc Natl Acad Sci U S A 100 2003 5807 5812
27. D.L. Alge, D. Zhou, and L.L. Adams et al. Donor-matched comparison of dental pulp stem cells and bone marrow-derived mesenchymal stem cells in a rat model J Tissue Eng Regen Med 4 2010 73 81
28. W. Zhang, X.F. Walboomers, and S. Shi et al. Multilineage differentiation potential of stem cells derived from human dental pulp after cryopreservation Tissue Eng 12 2006 2813 2823
29. K. Sakai, A. Yamamoto, and K. Matsubara et al. Human dental pulp-derived stem cells promote locomotor recovery after complete transection of the rat spinal cord by multiple neuro-regenerative mechanisms J Clin Invest 122 2012 80 90
30. W. Sonoyama, Y. Liu, and T. Yamaza et al. Characterization of the apical papilla and its residing stem cells from human immature permanent teeth: a pilot study J Endod 34 2008 166 171
31. C. Morsczeck, W. Gotz, and J. Schierholz et al. Isolation of precursor cells (PCs) from human dental follicle of wisdom teeth Matrix Biol 24 2005 155 165
32. B.M. Seo, M. Miura, and S. Gronthos et al. Investigation of multipotent postnatal stem cells from human periodontal ligament Lancet 364 2004 149 155
33. X. Xu, C. Chen, and K. Akiyama et al. Gingivae contain neural-crest- and mesoderm-derived mesenchymal stem cells J Dent Res 92 2013 825 832
34. V.T. Sakai, M.M. Cordeiro, and Z. Dong et al. Tooth slice/scaffold model of dental pulp tissue engineering Adv Dent Res 23 2011 325 332
35. M.M. Cordeiro, Z. Dong, and T. Kaneko et al. Dental pulp tissue engineering with stem cells from exfoliated deciduous teeth J Endod 34 2008 962 969
36. L. Casagrande, F.F. Demarco, and Z. Zhang et al. Dentin-derived BMP-2 and odontoblast differentiation J Dent Res 89 2010 603 608
37. L.W. Bento, Z. Zhang, and A. Imai et al. Endothelial differentiation of SHED requires MEK1/ERK signaling J Dent Res 92 2013 51 57
38. V.T. Sakai, Z. Zhang, and Z. Dong et al. SHED differentiate into functional odontoblasts and endothelium J Dent Res 89 2010 791 796
39. P.E. Murray, F. Garcia-Godoy, and K.M. Hargreaves Regenerative endodontics: a review of current status and a call for action J Endod 33 2007 377 390
40. Y.N. Wu, J.N. Shi, and L.Z. Huang et al. Variables affecting electronic root canal measurement Int Endod J 25 1992 88 92
41. D.J. Roberts-Clark, and A.J. Smith Angiogenic growth factors in human dentine matrix Arch Oral Biol 45 2000 1013 1016
42. R. Zhang, P.R. Cooper, and G. Smith et al. Angiogenic activity of dentin matrix components J Endod 37 2011 26 30
43. A.J. Smith, R.S. Tobias, and C.G. Plant et al. In vivo morphogenetic activity of dentine matrix proteins J Biol Buccale 18 1990 123 129
44. C. Begue-Kirn, A.J. Smith, and J.V. Ruch et al. Effects of dentin proteins, transforming growth factor beta 1 (TGF beta 1) and bone morphogenetic protein 2 (BMP2) on the differentiation of odontoblast in vitro Int J Dev Biol 36 1992 491 503
45. D. Tziafas, A. Alvanou, and N. Panagiotakopoulos et al. Induction of odontoblast-like cell differentiation in dog dental pulps after in vivo implantation of dentine matrix components Arch Oral Biol 40 1995 883 893
46. S. Zhao, A.J. Sloan, and P.E. Murray et al. Ultrastructural localisation of TGF-beta exposure in dentine by chemical treatment Histochem J 32 2000 489 494
47. J.C. Farges, A. Romeas, and M. Melin et al. TGF-beta1 induces accumulation of dendritic cells in the odontoblast layer J Dent Res 82 2003 652 656
48. S.M. Baker, R.V. Sugars, and M. Wendel et al. TGF-beta/extracellular matrix interactions in dentin matrix: a role in regulating sequestration and protection of bioactivity Calcif Tissue Int 85 2009 66 74
49. L. Graham, P.R. Cooper, and N. Cassidy et al. The effect of calcium hydroxide on solubilisation of bio-active dentine matrix components Biomaterials 27 2006 2865 2873
50. P.L. Tomson, L.M. Grover, and P.J. Lumley et al. Dissolution of bio-active dentine matrix components by mineral trioxide aggregate J Dent 35 2007 636 642
51. P. Laurent, J. Camps, and I. About Biodentine(TM) induces TGF-beta1 release from human pulp cells and early dental pulp mineralization Int Endod J 45 2012 439 448
52. J.L. Ferracane, P.R. Cooper, and A.J. Smith Dentin matrix component solubilization by solutions of pH relevant to self-etching dental adhesives J Adhes Dent 15 2013 407 412
53. K.M. Galler, J.D. Hartgerink, and A.C. Cavender et al. A customized self-assembling peptide hydrogel for dental pulp tissue engineering Tissue Eng Part A 18 2012 176 184
54. A. Zieris, S. Prokoph, and K.R. Levental et al. FGF-2 and VEGF functionalization of starPEG-heparin hydrogels to modulate biomolecular and physical cues of angiogenesis Biomaterials 31 2010 7985 7994
55. J. Manson, and D. Dixon The influence of solvent processing on polyester bioabsorbable polymers J Biomater Appl 26 2012 623 634
56. K. Dobie, G. Smith, and A.J. Sloan et al. Effects of alginate hydrogels and TGF-beta 1 on human dental pulp repair in vitro Connect Tissue Res 43 2002 387 390
57. H.H. Tonnesen, and J. Karlsen Alginate in drug delivery systems Drug Dev Ind Pharm 28 2002 621 630
58. H. Zimmermann, D. Zimmermann, and R. Reuss et al. Towards a medically approved technology for alginate-based microcapsules allowing long-term immunoisolated transplantation J Mater Sci Mater Med 16 2005 491 501
59. S.I. Jeong, M.D. Krebs, and C.A. Bonino et al. Electrospun alginate nanofibers with controlled cell adhesion for tissue engineering Macromol Biosci 10 2010 934 943
60. B. Palma Santana, F. Nedel, and E. Piva et al. Preparation, modification, and characterization of alginate hydrogel with nano-/microfibers: a new perspective for tissue engineering Biomed Res Int 2013 2013 307602
61. Y.M. Kolambkar, K.M. Dupont, and J.D. Boerckel et al. An alginate-based hybrid system for growth factor delivery in the functional repair of large bone defects Biomaterials 32 2011 65 74
62. H.J. Chung, H.K. Kim, and J.J. Yoon et al. Heparin immobilized porous PLGA microspheres for angiogenic growth factor delivery Pharm Res 23 2006 1835 1841
63. B.N. Cavalcanti, B.D. Zeitlin, and J.E. Nor A hydrogel scaffold that maintains viability and supports differentiation of dental pulp stem cells Dent Mater 29 2013 97 102
64. Y. Zhao, S. Gao, and S. Zhao et al. Synthesis and characterization of disulfide-crosslinked alginate hydrogel scaffolds Mater Science Engin 32 2012 2153 2162
65. A. Zieris, K. Chwalek, and S. Prokoph et al. Dual independent delivery of pro-angiogenic growth factors from starPEG-heparin hydrogels J Control Release 156 2011 28 36
66. K.W. Lee, J.J. Yoon, and J.H. Lee et al. Sustained release of vascular endothelial growth factor from calcium-induced alginate hydrogels reinforced by heparin and chitosan Transplant Proc 36 2004 2464 2465
67. R. Paul, Z.G. Zhang, and B.P. Eliceiri et al. Src deficiency or blockade of Src activity in mice provides cerebral protection following stroke Nat Med 7 2001 222 227
68. P. Matricardi, M. Pontoriero, and T. Coviello et al. In situ cross-linkable novel alginate-dextran methacrylate IPN hydrogels for biomedical applications: mechanical characterization and drug delivery properties Biomacromolecules 9 2008 2014 2020
69. G. McLennan, M.S. Johnson, and K.R. Stookey et al. Kinetics of release of heparin from alginate hydrogel J Vasc Interv Radiol 11 2000 1087 1094
70. I. Freeman, and S. Cohen The influence of the sequential delivery of angiogenic factors from affinity-binding alginate scaffolds on vascularization Biomaterials 30 2009 2122 2131
71. I. Freeman, A. Kedem, and S. Cohen The effect of sulfation of alginate hydrogels on the specific binding and controlled release of heparin-binding proteins Biomaterials 29 2008 3260 3268
72. O. Jeon, C. Powell, and L.D. Solorio et al. Affinity-based growth factor delivery using biodegradable, photocrosslinked heparin-alginate hydrogels J Control Release 154 2011 258 266
73. E. Rondeau, and J.J. Cooper-White Biopolymer microparticle and nanoparticle formation within a microfluidic device Langmuir 24 2008 6937 6945
74. S.J. Buwalda, L.B. Perez, and S. Teixeira et al. Self-assembly and photo-cross-linking of eight-armed PEG-PTMC star block copolymers Biomacromolecules 12 2011 2746 2754
75. O. Khanna, J.C. Larson, and M.L. Moya et al. Generation of alginate microspheres for biomedical applications J Vis Exp 66 2012 3388
76. O. Khanna, M.L. Moya, and E.C. Opara et al. Synthesis of multilayered alginate microcapsules for the sustained release of fibroblast growth factor-1 J Biomed Mater Res A 95 2010 632 640
77. H. Tawfik, A.M. Abu-Seida, and A.A. Hashem et al. Regenerative potential following revascularization of immature permanent teeth with necrotic pulps Int Endod J 46 2013 910 922
78. X. Wang, B. Thibodeau, and M. Trope et al. Histologic characterization of regenerated tissues in canal space after the revitalization/revascularization procedure of immature dog teeth with apical periodontitis J Endod 36 2010 56 63
79. V. Rosa, Z. Zhang, and R.H. Grande et al. Dental pulp tissue engineering in full-length human root canals J Dent Res 92 2013 970 975
80. Y.H. Wang, B. Rutherford, and W.B. Upholt et al. Effects of BMP-7 on mouse tooth mesenchyme and chick mandibular mesenchyme Dev Dyn 216 1999 320 335
81. R.B. Rutherford, J. Wahle, and M. Tucker et al. Induction of reparative dentine formation in monkeys by recombinant human osteogenic protein-1 Arch Oral Biol 38 1993 571 576
82. S. Jepsen, H.K. Albers, and B. Fleiner et al. Recombinant human osteogenic protein-1 induces dentin formation: an experimental study in miniature swine J Endod 23 1997 378 382
83. M. Nakashima Induction of dentin formation on canine amputated pulp by recombinant human bone morphogenetic proteins (BMP)-2 and -4 J Dent Res 73 1994 1515 1522
84. M. Nakashima Induction of dentine in amputated pulp of dogs by recombinant human bone morphogenetic proteins-2 and -4 with collagen matrix Arch Oral Biol 39 1994 1085 1089
85. X. Yang, P.M. van der Kraan, and Z. Bian et al. Mineralized tissue formation by BMP2-transfected pulp stem cells J Dent Res 88 2009 1020 1025
86. T. Suzuki, C.H. Lee, and M. Chen et al. Induced migration of dental pulp stem cells for in vivo pulp regeneration J Dent Res 90 2011 1013 1018
87. F. Decup, N. Six, and B. Palmier et al. Bone sialoprotein-induced reparative dentinogenesis in the pulp of rat's molar Clin Oral Investig 4 2000 110 119
88. N. Six, F. Decup, and J.J. Lasfargues et al. Osteogenic proteins (bone sialoprotein and bone morphogenetic protein-7) and dental pulp mineralization J Mater Sci Mater Med 13 2002 225 232
89. R.N. D'Souza, T. Aberg, and J. Gaikwad et al. Cbfa1 is required for epithelial-mesenchymal interactions regulating tooth development in mice Development 126 1999 2911 2920
90. J.S. Gaikwad, M. Hoffmann, and A. Cavender et al. Molecular insights into the lineage-specific determination of odontoblasts: the role of Cbfa1 Adv Dent Res 15 2001 19 24
91. A. George, R. Silberstein, and A. Veis In situ hybridization shows Dmp1 (AG1) to be a developmentally regulated dentin-specific protein produced by mature odontoblasts Connect Tissue Res 33 1995 67 72
92. A. Siyam, S. Wang, and C. Qin et al. Nuclear localization of DMP1 proteins suggests a role in intracellular signaling Biochem Biophys Res Commun 424 2012 641 646
93. A. Abd-Elmeguid, D.C. Yu, and L.W. Kline et al. Dentin matrix protein-1 activates dental pulp fibroblasts J Endod 38 2012 75 80
94. R.S. Prescott, R. Alsanea, and M.I. Fayad et al. In vivo generation of dental pulp-like tissue by using dental pulp stem cells, a collagen scaffold, and dentin matrix protein 1 after subcutaneous transplantation in mice J Endod 34 2008 421 426
95. M. MacDougall, D. Simmons, and X. Luan et al. Dentin phosphoprotein and dentin sialoprotein are cleavage products expressed from a single transcript coded by a gene on human chromosome 4. Dentin phosphoprotein DNA sequence determination J Biol Chem 272 1997 835 842
96. M.P. Gibson, Q. Zhu, and S. Wang et al. The rescue of dentin matrix protein 1 (DMP1)-deficient tooth defects by the transgenic expression of dentin sialophosphoprotein (DSPP) indicates that DSPP is a downstream effector molecule of DMP1 in dentinogenesis J Biol Chem 288 2013 7204 7214
97. H.H. Ritchie, J.E. Berry, and M.J. Somerman et al. Dentin sialoprotein (DSP) transcripts: developmentally-sustained expression in odontoblasts and transient expression in pre-ameloblasts Eur J Oral Sci 105 1997 405 413
98. S.Y. Lee, S.Y. Kim, and S.H. Park et al. Effects of recombinant dentin sialoprotein in dental pulp cells J Dent Res 91 2012 407 412
99. W.T. Butler, and H. Ritchie The nature and functional significance of dentin extracellular matrix proteins Int J Dev Biol 39 1995 169 179
100. Y.S. Kim, K.S. Min, and D.H. Jeong et al. Effects of fibroblast growth factor-2 on the expression and regulation of chemokines in human dental pulp cells J Endod 36 2010 1824 1830
101. H. Ishimatsu, C. Kitamura, and T. Morotomi et al. Formation of dentinal bridge on surface of regenerated dental pulp in dentin defects by controlled release of fibroblast growth factor-2 from gelatin hydrogels J Endod 35 2009 858 865
102. M.Y. Shao, R. Cheng, and F.M. Wang et al. Beta-Catenin and Rho GTPases as downstream targets of TGF-beta1 during pulp repair Cell Biol Int 35 2011 105 109
103. E.L. Scheller, J. Chang, and C.Y. Wang Wnt/beta-catenin inhibits dental pulp stem cell differentiation J Dent Res 87 2008 126 130
104. A. Erlebacher, E.H. Filvaroff, and J.Q. Ye et al. Osteoblastic responses to TGF-beta during bone remodeling Mol Biol Cell 9 1998 1903 1918
105. J. Liu, T. Jin, and S. Chang et al. Matrix and TGF-beta-related gene expression during human dental pulp stem cell (DPSC) mineralization Vitro Cell Dev Biol Anim 43 2007 120 128
106. Y. Lu, Y. Li, and A.C. Cavender et al. Molecular studies on the roles of Runx2 and Twist1 in regulating FGF signaling Dev Dyn 241 2012 1708 1715
107. Y. Li, Y. Lu, and I. Maciejewska et al. TWIST1 promotes the odontoblast-like differentiation of dental stem cells Adv Dent Res 23 2011 280 284
108. N. Ferrara VEGF: an update on biological and therapeutic aspects Curr Opin Biotechnol 11 2000 617 624
109. N. Ferrara, and W.J. Henzel Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells Biochem Biophys Res Commum 161 1989 851 858