Prospects for tooth regeneration in the 21st century: A perspective

Microscopy Research and Technique

Volumn 60, Issue 5, 2003, Pages 469-479

  Chai, Yang ^a   Slavkin, Harold C ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Dental implants; Growth factors; Molecular regulation of tooth morphogenesis; Stem cells; Tooth allo and autotransplantation; Transcription factors

Indexed keywords

BIOMIMETICS; BONE; CYTOLOGY; DENTAL PROSTHESES; HISTOLOGY; MOLECULAR BIOLOGY; MORPHOLOGY; TISSUE REGENERATION;

ADULT STEM CELLS; BIOLOGICAL PROCESS; CELLULARS; GROWTH FACTOR; MOLECULAR REGULATION; MOLECULAR REGULATION OF TOOTH MORPHOGENESIS; ODONTOGENIC; STEM-CELL; TOOTH ALLO- AND AUTOTRANSPLANTATION; TOOTH REGENERATION;

STEM CELLS;

BIOMIMETICS; BONE TISSUE; CARTILAGE; CELL KINETICS; DENTIN; DEVELOPMENTAL BIOLOGY; EMBRYOLOGY; HUMAN; MESENCHYME; MOLECULAR BIOLOGY; MORPHOGENESIS; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROCESS DEVELOPMENT; QUALITY OF LIFE; REGENERATION; REVIEW; STEM CELL; TOOTH DEVELOPMENT;

EID: 0037376984     PISSN: 1059910X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jemt.10287     Document Type: Review

References (101)

1. Andreasen JO, Paulsen JH, Yu Z, Bayer T, Schwartz O. 1990. A long term study of 370 autotransplanted premolars. Eur J Orthodont 12:3-50.
2. Araki T, Tsukiboshi M. 1992. Science and the state of art autogenous tooth transplantation. Regeneration of alveolar bone proper and Sharpey's fiber, revascularization, and reinnervation [in Japanese]. Quintessence 11:725-748.
3. Artinger KB, Chitnis AB, Mercola M, Driever W. 1999. Zebrafish narrowminded suggests a genetic link between formation of neural crest and primary sensory neurons. Development 126:3969-3979.
4. Bei M, Maas R. 1998. FGFs and BMP4 induce both Msx-dependent signaling pathways in early tooth development. Development 125:4325-4333.
5. Bianco P, Robey PG. 2001. Stem cells in tissue engineering. Nature 414:118-121.
6. Bianco P, Riminucci M, Gronthos S, Robey PG. 2001. Bone marrow stromal stem cells: nature biology, and potential applications. Stem Cells 19:180-192.
7. Bitgood MJ, McMahon AP. 1995. Hedgehog and BMP genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo. Dev Biol 172:126-138.
8. Bronner-Fraser M. 1993. Mechanisms of neural crest migration. BioEssays 15:221-230.
9. Bronner-Fraser M. 1995. Origins and developmental potential of the neural crest. Exp Cell Res 2:405-417.
10. Branemark PI, Zarb GA, Albrektsson T. 1985. Tissue-integrated prostheses: osseointegration in clinical dentistry. Chicago: Quintessence.
11. Carlesso N, Aster JC, Sklar J, Scadden DT. 1999. Notch 1-induced delay of human hematopoietic progenitor cell differentiation is associated with altered cell cycle kinetics. Blood 93:838-848.
12. Chai Y, Mah A, Crohin C, Froff S, Bringas P Jr, Le T, Santos V, Slavkin HC. 1994. Specific transforming growth factor-β subtypes regulate embryonic mouse Meckel's cartilage and tooth development. Dev Biol 162:85-103.
13. Chai Y, Bringas P Jr, Shuler C, Devaney E, Grosshedl R, Slavkin HC. 1998. A mouse mandibular culture model permits the study of neural crest cell migration and tooth development. Int J Dev Biol 42:87-94.
14. Chai Y, Zhao J, Mogharei A, Xu B, Bringas P Jr, Shuler C, Warburton D. 1999. Inhibition of transforming growth factor-β type II receptor signaling accelerates tooth formation in mouse first branchial arch explants. Mech Dev 86:63-74.
15. Chai Y, Jiang X, Ito Y, Bringas P Jr, Han J, Rowitch D, Soriano P, McMahon A, Sucov H. 2000. Fate of the mammalian cranial neural crest during tooth and mandibular morphogenesis. Development 127:1671-1679.
16. Cobourne MT, Hardcastle Z, Sharpe PT. 2001. Sonic hedgehog regulates epithelial proliferation and cell survival in the developing tooth germ. J Dent Res 11:1974-1979.
17. Dassule H, McMahon A. 1998. Analysis of epithelial-mesenchymal interactions in the initial morphogenesis of the mammalian tooth. Dev Biol 202:215-227.
18. Dassule H, Lewis P, Bei M, Maas R, McMahon AP. 2000. Sonic hedgehog regulates growth and morphogenesis of the tooth. Development 127:4775-4785.
19. Donovan P, Gearhart J. 2001. The end of the beginning for pluripotent stem cells. Nature 414:92-97.
20. Dorsky RI, Moon RT, Raible DW. 1998. Control of neural crest cell fate by the Wnt signaling pathway. Nature 396:370-373.
21. Echelard Y, Vassileva G, McMahon AP. 1994. Cis-acting regulatory sequences governing Wnt-awxpression in the developing mouse CNS. Development 120:2213-2224.
22. Ferguson CA, Tucker AS, Christensen L, Lau AL, Matzuk MM, Sharpe PT. 1998. Activin is an essential early mesenchymal signal in tooth development that is required for patterning of the murine dentition. Genes Dev 12:2636-2649.
23. Ferrari G, Cusella-De Angelis G, Coletta M, Paolucci E, Stornaiuolo A, Cossu G, Mavilio F. 1998. Muscles regeneration by bone marrow-derived myogenic progenitors. Science 279:1528-1530.
24. Glasstone S. 1936. The development of tooth germs in vitro. J Anat 70:260-266.
25. Glasstone S. 1954. The development of tooth germs on the chick chorio-allantois. J Anat 88:392-399.
26. Gorlin RJ, Slavkin HC. 1997. Embryology of the face. In: Tewfik TL, DerKaloustian V, editors. Congenital anomalies of the ear, nose, and throat. New York: Oxford University Press; p 287-296.
27. Graham A, Lumsden A. 1993. The role of segmentation in the development of the branchial region of higher vertebrate embryos. In: Opitz JM, editor. Blastogenesis, normal and abnormal. New York: Wiley-Liss Publishers; p 99-108.
28. Grigoriou M, Tucker AS, Sharpe PT, Pachnis V. 1998. Expression and regulation of Lhx6 and Lhx7, a novel subfamily of LIM homeodomain encoding genes, suggests a role in mammalian head development. Development 125:2063-2074.
29. Gronthos S, Mankani M, Brahim J, Robey PG, Shi S. 2000. Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo. Proc Nat Acad Sci 97:13625-13630.
30. Guerini V. 1909. A history of dentistry in the most ancient times until the end of the eighteenth century. Philadelphia: Lea & Febiger; p 280-336.
31. Harada H, Kettunen P, Jung HS, Mustonen T, Wang YA, Thesleff I. 1999. Localization of putative stem cells in dental epithelium and their association with Notch and FGF signaling. J Cell Biol 147:105-120.
32. Hardcastle Z, Mo R, Hui CC, Sharpe P. 1998. The Shh signaling pathway in tooth development: defects in Gli2 and Gli3 mutants. Development 125:2803-2811.
33. Herbarth B, Pingault V, Bondurand N, Kuhlbrodt K, Hermans-Brogmeyer I, Puliti A, Lemort N, Goossens M, Wegner M. 1998. Mutation of the Sry-related Sox10 gene in dominant megacolon, a mouse model for human Hirschsprung disease. Proc Nat Acad Sci 95:5161-5165.
34. Ikeya M, Lee SM, Johnson JE, McMahon AP, Takada S. 1997. Wnt Signaling required for expansion of neural crest and CNS progenitors. Nature 389:966-970.
35. Imai H, Osumi-Yamashita N, Ninomiya Y, Eto K. 1996. Contribution of early-emigrating midbrain crest cells to the dental mesenchyme of madibular molar teeth in rat embryos. Dev Biol 176:151-165.
36. Jernvall J, Aberg T, Kettunen P, Keranen S, Thesleff I. 1998. The life history of an embryonic signaling center: BMP-4 induces p21 and is associated with apoptosis in the mouse tooth enamel knot. Development 125:161-169.
37. Jernvall J, Thesleff I. 2000. Reiterative signaling and patterning during mammalian tooth morphogenesis. Mech Dev 92:19-29.
38. Koch WE. 1972. Tissue Interaction during in Vitro Odontogenesis. In: Slavkin HC, Bavetta LA, editors. Developmental aspects of oral biology. New York: Academic Press Inc.; p 151-163.
39. Kollar EJ, Baird G. 1969. The influence of the dental papilla on the development of tooth shape in embryonic mouse tooth germs. J Embryol Exp Morph 21:131-148.
40. Kollar EJ. 1972. Histogenetic aspects of dermal-epidermal interactions. In: Slavkin HC, Bavetta LA, editors. Developmental aspects of oral biology. New York: Academic Press Inc.; p 126-149.
41. Kontges G, Lumsden A. 1996. Rhombencephalic neural crest segmentation is preserved throughout craniofacial ontogeny. Development 122:3229-3242.
42. Kotton DN, Ma BY, Cardoso WV, Sanderson EA, Summer RS, Williams MC, Fine A. 2001. Bone marrow-derived cells as progenitors of lung alveolar epithelium. Development 128:5181-5188.
43. Koyama E, Wu C, Shimo T, Pacifici M. 2003. Chick limbs with mouse teeth: an effective in vivo culture system for tooth germ development and analysis. Dev Dyn 226:149-154.
44. LaBonne C, Bronner-Fraser M. 1999. Molecular mechanisms of neural crest formation. Annu Rev Cell Dev Biol 15:81-112.
45. Lagasse E, Connors H, Al-Dhalimy M, Reitsama M, Dohse M, Osborne L, Wang X, Finegold M, Weissman IL, Grompe M. 2000. Purified hematopoietic stem cell can differentiate into hepatocytes in vivo. Nat Med 6:1229-1234.
46. Le Douarin N, Ziller C, Coul G. 1993. Patterning of neural crest derivatives in the avian embryo: In vivo and in vitro studies. Develop Biol 159:24-49.
47. Lekholm U, Van Steenberghe D, Herrmann I, Bolender C, Folmer T, Gunne J, et al. 1994. Osseointegrated implants in the treatment of partially edentulous jaws: A prospective 5-year multicenter study. Int J Oral Maxillofac Implants 9:627-635.
48. Lin CR, Kioussi C, O'Connell S, Briata P, Szeto D, Liu F, Izpisua-Belmonte JC, Rosenfeld MG. 1999. Pitx2 regulates lung asymmetry, cardiac positioning and pituitary and tooth morphogenesis. Nature 401:279-282.
49. Lovell-Badge R. 2001. The future for stem cell research. Nature 414:88-91.
50. Lu MF, Pressman C, Dyer R, Johnson RL, Martin JF. 1999. Function of Rieger syndrome gene in left-right asymmetry and craniofacial development. Nature 401:276-278.
51. Lumsden A. 1988. Spatial organization of the epithelium and the role of neural crest cells in the initiation of the mammalian tooth. Development 103:55-169.
52. Lumsden A, Krumlauf R. 1996. Patterning the vertebrate neuraxis. Science 274:1109-1115.
53. Main JHP. 1972. Developmental considerations: carcinogenesis and oncology. In: Slavkin HC, Bavetta LA, editors. Developmental aspects of oral biology. New York: Academic Press Inc.; p 385-417.
54. Mina M, Kollar EJ. 1987. The induction of odontogenesis in non-dental mesenchyme combined with early murine mandibular arch epithelium. Arch Oral Biol 2:123-127.
55. Mooney DJ, Powell C, Piana J, Rutherford B. 1996. Engineering dental pulp-like tissue in vitro. Biotechnol Prog 12:865-868.
56. Moore KL, Persaud TVN. 1998. The developing human, 6th ed. Philadelphia: W.B. Saunders Co.; p 215-256.
57. Neubuser A, Peter H, Balling R, Martin GR. 1997. Antagonistic interactions between FGF and BMP signaling pathways: a mechanism for positioning the sites of tooth formation. Cell 90:247-255.
58. Noden DM. 1983. The role of the neural crest in patterning of avian cranial skeletal, connective, and muscle tissue. Dev Biol 96:144-165.
59. Noden DM. 1991. Cell movements and control of patterned tissue assembly during craniofacial development. J Craniofac Genet Dev Biol 4:192-213.
60. Nuckolls GH, Shum L, Slavkin HC, 1999a. Progress toward understanding craniofacial malformations. Cleft Palate Craniofac J 36:12-26.
61. Nuckolls GH, Slavkin HC, Shum L. 1999b. Bone morphogenetic protein signaling in limb and craniofacial development. In: Davidowitch Z, editor. Proceedings of the biological mechanisms of tooth eruption, resorption and replacement by implants. Harvard's Society for the Advancement of Orthodontics. Brimingham, AL: EBSCO Media; p 39-47.
62. Osumi-Yamashita N, Noji S, Nohno T, Koyama E, Doi H, Eto K, Taniguchi S. 1990. Expression of retinoic acid receptor genes in neural crest-derived cells during mouse facial development. FEBS Lett 264:71-74.
63. Rieger HH. 1935. Beitrage zur Kenntnis Seltener Missbildungen der Iris. Graefes Arch Clin Exp Opthalmol 133:602-635.
64. Ring ME. 1992. Dentistry: an illustrated history. New York: Abradale Press, Harry N Adams Inc.
65. Romer AS. 1972. The vertebrate as a dual animal-somatic and visceral. Evolut Biol 6:121-156.
66. Saldivar JR, Sechrist JW, Krull CE, Ruffins S, Bronner-Fraser M. 1997. Dorsal hindbrain ablation results in rerouting of neural crest migration and changes in gene expression, but normal hyoid development. Development 14:2729-2739.
67. Sarkar L, Cobourne M, Naylor S, Smalley M, Dale T, Sharpe PT. 2000. Wnt/Shh interactions regulate ectodermal boundary formation during mammalian tooth development. Proc Natl Acad Sci 97:4520-4524.
68. Selleck MAJ, Scherson TY, Bronner-Fraser M. 1993. Origins of neural crest cell diversity. Dev Biol 159:1-11.
69. Semina EV, Reiter R, Leysens NJ, Alward WL, Small KW, Datson NA, Siegel-Bartelt J, Bierke-Nelson D, Bitoun P, Zabel BU, Carey JC, Murray JC. 1996. Cloning and characterization of a novel bicoid-related homeobox transcription factor gene, RIEG, involved in Rieger syndrome. Nat Genet 14:392-399.
70. Serbedzija GN, Bronner-Fraser M, Fraser SE. 1992. Vital dye analysis of cranial neural crest cell migration in the mouse embryo. Development 116:297-307.
71. Shah N, Groves A, Anderson D. 1996. Alternative neural crest cell fates are instructively promoted by TGFβ superfamily members. Cell 85:331-343.
72. Sharpe PT. 1995. Homeobox genes and orofacial development. Connect Tissue Res 32:17-25.
73. Shah N, Anderson D. 1997. Integration of multiple instructive cues by neural crest stem cell reveals cell-intrinsic biases in relative growth factor responsiveness. Proc Natl Acad Sci USA. 94:11369-11374.
74. Sherr CJ, Roberts JM. 1999. CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev 13:1501-1512.
75. Shum L, Takahashi K, Takahashi I, Nagata M, Tan DP, Semba I, Tanaka O, Bringas P, Nuckolls G, Slavkin HC. 2000. Embryogenesis and the classification of craniofacial dysmorphogenesis. In: Fonseca RJ, editor. Oral and maxillofacial surgery. Philadelphia: W. B. Saunders Co.; p 149-194.
76. Slavkin HC. 1972. Intercellular communication during odontogenesis. In: Slavkin HC, Bavetta LA, editors. Developmental aspects of oral biology. New York: Academic Press Inc.; p 165-197.
77. Slavkin HC. 1974. Epithelial-mesenchymal induction. (Collection of five previously published papers). In: Acton RT, editor. Cellular induction: series on the mechanism of cell-cell interaction and communication. New York: MSS Information Corp.; p 9-79.
78. Slavkin HC. 1988. Molecular biology of dental development: a review. In: Davidovitch Z, editor. Biological mechanisms of tooth eruption and root resorption. Birmingham, AL: Ebsco Media; p 107-116.
79. Slavkin HC. 1992. Intercellular communication during odontogenesis. In: Slavkin HC, Bavetta LA, editors. Developmental aspects of oral biology. New York: Academic Press; p 165-201.
80. Slavkin HC. 1997. Regulation of embryogenesis. In: Polin R, Fox W, editors. Fetal and neonatal physiology, 2nd ed. Philadelphia: WB Saunders Co.; p 37-47.
81. Slavkin HC, Bavetta LA. 1968a. Odontogenesis in vivo and in xenografts on chick chorioallantois. I. Collagen and hexosamine biosynthesis. Arch Oral Biol 13:145-154.
82. Slavkin HC, Bavetta LA. 1968b. Organogenesis: prolonged differentiation and growth of tooth primordia on the chick chorio-allantoic membrane. Experientia 24:1922-194.
83. Slavkin HC, Beierle J, Bavetta LA. 1968. Odontogenesis: cell-cell interactions in vitro. Nature (London) 217:269-270.
84. Slavkin HC, Trump GN, Brownell AG, Sorgente N. 1977. Epithelial-mesenchymal interactions: mesenchymal specificity. In: Lash JW, Burger MM, editors. Cell and tissue interactions. New York: Raven Press; p 29-46.
85. Slavkin HC, Zeichner-David M, Snead ML, Bessem C, Santos V. 1984. epithelialmesenchymal interactions and enamel gene induction-phylogenetic implications. In: Fernhead W, Suga S, editors. Tooth enamel IV. Amsterdam: Elsevier/North Holland Publishers; p167-171.
86. Slavkin HC, Chai Y, Hu CC, Millar-Groff S, Bringas Jr P. 1994. Intrinsic molecular determinants of tooth development from specification to root formation: a review. In: Davidovitch Z, editor. Biological mechanisms of tooth eruption, resorption and replacement by implants. Birmingham, Alabama: EBSCO Media; p 263-272.
87. Slavkin HC, Shum L, Nuckolls GH. 1998. Ectodemal dysplasia: a synthesis between evolutionary, development and molecular biology and human clinical genetics. In: Chuong CM, editor. Molecular basis of epithelial appendage morphogenesis. Austin, TX: Landes Science Publishers; p 15-37.
88. Slavkin HC, Nuckolls G, Shum L. 2000. Craniofacial development and patterning. Methods Mol Biol 136:45-54.
89. St. Amand TR, Zhang Y, Semina EV, Zhao X, Hu Y, Nguyen L, Murray JC, Chen Y. 2000. Antagonistic signals between BMP4 and FGF8 define the expression of Pitx1 and Pitx2 in mouse tooth-forming anlage. Dev Biol 15:323-332.
90. Takahashi K, Nuckolls G, Tanaka O, Semba I, Takahashi I, Dashner R, Shum L, Slavkin HC. 1998. Adenovirus mediated ectopic expression of MSX? in even-numbered rhombomeres induces apoptotic elimination of cranial neural crest cells in ovo. Development 125:1627-1635.
91. Tan SS, Morriss-Kay GM. 1986. The development and distribution of the cranial neural crest in the rat embryo. Cell Tiss Res 240:403-416.
92. Thesleff I, Sharpe P. 1997. Signaling networks regulating dental development. Mech Dev 67:111-123.
93. Thomas BL, Tucker AS, Qui M, Ferguson CA, Hardcastle Z, Rubenstein JL, Sharpe P. 1997. Role of Dlx-1 and Dlx-2 genes in patterning of the murine dentition. Development 124:4811-4818.
94. Tsukiboshi M. 1999. Autotransplantation of teeth. Tokyo: Quintessence Publishing Co. Inc.
95. Trainor P, Krumlauf R. 2000. Plasticity in mouse neural crest cells reveals a new patterning role for cranial mesoderm. Nat Cell Biol 2:96-102.
96. Trumpp A, Depew MJ, Rubenstein JL, Bishop JM, Martin GR. 1999. Cre-mediated gene inactivation demonstrates that FGF8 is required for cell survival and patterning of the first branchial arch. Genes Dev 13:3136-3148.
97. Tucker AS, Sharpe PT. 1999. Molecular genetics of tooth morphogenesis and patterning: the right shape in the right place. J Dent Res 78:826-834.
98. Tucker AS, Matthews KL, Sharpe P. 1998. Transformation of tooth type induced by inhibition of BMP signaling. Science 82:1136-1138.
99. Vainio S, Karavanova I, Jowett A, Thesleff I. 1993. Identification of BMP-4 as a signal mediation secondary induction between epithelial and mesenchymal tissues during early tooth development. Cell 75:45-58.
100. Woo K, Fraser SE. 1998. Specification of the hindbrain fate in the zebrafish. Dev Biol 197:283-296.
101. Woodbury D, Schwarz EJ, ProComm DJ, Black IB. 2000. Adult rat and human bone marrow stromal cells differentiate into neurons. Neurotics Res 61:364-370.