The rescue of dentin matrix protein 1 (DMP1)-deficient tooth defects by the transgenic expression of dentin sialophosphoprotein (DSPP) indicates that DSPP is a downstream effector molecule of DMP1 in dentinogenesis

Journal of Biological Chemistry

Volumn 288, Issue 10, 2013, Pages 7204-7214

  Gibson, Monica Prasad ^a   Zhu, Qinglin ^a   Wang, Suzhen ^a   Liu, Qilin ^a   Liu, Ying ^a   Wang, Xiaofang ^a   Yuan, Baozhi ^b   Ruest, L Bruno ^a   Feng, Jian Q ^a   D'Souza, Rena N ^a   Qin, Chunlin ^a   Lu, Yongbo ^a  

^a TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DENTIN MATRIX PROTEINS; FUNCTIONAL RELATIONSHIP; IN-VITRO; IN-VIVO; KNOCKOUT MICE; TRANSGENIC EXPRESSION;

DEFECTS; PROTEINS;

MOLECULES;

DENTIN MATRIX PROTEIN 1; MESSENGER RNA;

ALVEOLAR BONE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE DEFECT; BONE DEMINERALIZATION; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DENTIN SIALOPHOSPHOPROTEIN GENE; DOWN REGULATION; GENE; GENE EXPRESSION REGULATION; IN VITRO STUDY; IN VIVO STUDY; MESENCHYME CELL; MOUSE; NONHUMAN; ODONTOBLAST; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; TOOTH DEVELOPMENT; TOOTH MALFORMATION; TRANSGENIC MOUSE; UPREGULATION;

ANIMALS; BIGLYCAN; CELL DIFFERENTIATION; COLLAGEN TYPE I; DENTINOGENESIS; EXTRACELLULAR MATRIX PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HOMEODOMAIN PROTEINS; IMMUNOHISTOCHEMISTRY; MANDIBLE; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; ODONTOBLASTS; PHOSPHOPROTEINS; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIALOGLYCOPROTEINS; TOOTH; TOOTH ABNORMALITIES; TRANSCRIPTION FACTORS; X-RAY MICROTOMOGRAPHY;

EID: 84874928620     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.445775     Document Type: Article

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