Cbfa1 is required for epithelial-mesenchymal interactions regulating tooth development in mice

Development

Volumn 126, Issue 13, 1999, Pages 2911-2920

  D'Souza, Rena N ^b   Åberg, Thomas ^a   Gaikwad, Joel ^b   Cavender, Adriana ^b   Owen, Michael ^c   Karsenty, Gérard ^d   Thesleff, Irma ^a  

^a Viikki Biocenter   (Finland)

^b UNIVERSITY OF TEXAS   (United States)

^c IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Ameloblasts; Cbfal Osf2; Epithelial morphogenesis; Inductive signalling; Knockout mice; Odontoblasts; Odontogenesis

Indexed keywords

BONE MORPHOGENETIC PROTEIN; FIBROBLAST GROWTH FACTOR; TRANSCRIPTION FACTOR;

AMELOBLAST; ANIMAL TISSUE; ARTICLE; CELL INTERACTION; CONTROLLED STUDY; DENTIN; DEVELOPMENTAL GENETICS; EMBRYO; ENAMEL; EPITHELIUM CELL; GENE; GENE EXPRESSION; IN SITU HYBRIDIZATION; MESENCHYME; MOUSE; NEWBORN; NONHUMAN; ODONTOBLAST; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TOOTH DEVELOPMENT;

ANIMALS; BONE MORPHOGENETIC PROTEINS; CELL DIFFERENTIATION; CORE BINDING FACTOR ALPHA 1 SUBUNIT; EPITHELIUM; FIBROBLAST GROWTH FACTORS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; IN SITU HYBRIDIZATION; MESODERM; MICE; MICE, KNOCKOUT; MUTATION; NEOPLASM PROTEINS; ODONTOGENESIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; TOOTH; TRANSCRIPTION FACTORS;

ANIMALIA; MAMMALIA;

EID: 0032788735     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Åberg, T., Wozney, J. and Thesleff, I. (1997). Expression patterns of BMPs in the developing mouse tooth suggests roles in morphogenesis and cell differentiation. Dev. Dyn. 210, 407-416.
2. Bei, M. and Maas, R. (1998). FGFs and BMP4 induce both Msx-1 independent and Msx-1 dependent signaling pathways in early tooth development. Development 125, 4325-4333.
3. D'Souza, R. N., Cavender, A., Sunavala, G., Ohshima, A. J., Kulkarni, A. B. and MacDougall, M. (1997). Gene expression patterns of murine dentin matrix protein 1 (Dmp1) and dentin sialophosphoprotein (DSPP) suggests distinct developmental functions in vivo. J. Bone Miner. Res. 12, 2040-2049.
4. D'Souza, R. N., Niederreither, K. and de Crombrugghe, B. (1993). Osteoblast-specific expression of the alpha 2(I) collagen promoter in transgenic mice: correlation with the distribution of TGF-beta 1. J. Bone Mineral Res. 8, 1127-1136.
5. Ducy, P. and Karsenty, G. (1995). Two distinct osteoblast-specific cis-acting elements control expression of the mouse ostecalcin gene. Mol. Cell. Biol. 15, 1858-1869.
6. Ducy, P., Zhang, R., Geoffroy, V., Ridall, A. L. and Karsenty, G. (1997). Osf2/Cbfal: a transcriptional activator of osteoblast differentiation. Cell 89, 747-754.
7. Hall, B.K. (1978). Initiation of osteogenesis by mandibular mesenchyme. Arch. Oral Biol. 23, 1157-1161.
8. Hardcastle Z, Mo R, Hui CC, Sharpe PT (1998). The Shh signalling pathway in tooth development: defects in Gli2 and Gli3 mutants. Development 125, 2803-2811.
9. Henrique, D., Adam, J., Myat, A., Chitnis, A., Lewis, J and Ish-Horwicz, D. (1995). Expression of a Delta homologue in prospective neurons in the chick. Nature 375, 787-790.
10. Jernvall, J., Åberg, T., Kettunen, P., Keranen, S. and Thesleff, I. (1998). The life history of an embryonic signalling center: BMP-4 induces p21 and is associated with apoptosis in the mouse tooth enamel knot. Development 125, 161-169.
11. th Ed. Philadelphia: W.B. Saunders Company.
12. Komuri, T., Yagi, H., Nomura, S., Yamaguchi, A., Sasaki, K., Deguchi, K., Shimizu, Y., Bronson, R. T., Gao, Y. H., Inada, M., Sato, M., Okamoto, R., Kitamura, Y., Yoshiki, S. and Kishimoto, T. (1997). Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell 89, 755-764.
13. Lee, B., Thirunavukkarasu, K., Zhou, L., Pastore, L., Baldini, A., Hecht, J., Geoffroy, V., Ducy, P. and Karsenty, G. (1997). Missense mutations abolishing DNA binding of the osteoblast specific transcription factor OSF2/CBFA1 in cleidocranial dysplasia. Nature Genet. 16, 307-310.
14. Linde, A. and Goldberg, M. (1993). Dentinogenesis. Crit. Rev. Oral Biol. Med. 4, 679-728.
15. Lumsden, A. G. S.(1988). Spatial organisation of the epithelium and the role of neural crest cells in the initiation of the mammalian tooth. Development 103 Supplement, 155-169.
16. Maas, R. and Bei, M.(1997). The genetic control of early tooth development. Crit. Rev. Oral Biol. Med. 8, 4-39.
17. Matzuk, M. M., Kumar, T. R., Vassalli, A., Bickenbach, J. R., Roop, D. R., Jaenisch, R. and Bradley, A. (1995). Functional analysis of activins during mammalian development. Nature 374, 354-356.
18. Metsäranta, M., Toman, De., deCrombrugghe, B. and Vuorio, E. (1991). Specific hybridization probes for mouse type 1,2,3 and 9 collagen mRNA. Biochim. Biophys. Acta 18, 241-243.
19. Mina, M. and Kollar, E. J. (1987). The induction of odontogenesis in non-dental mesenchyme combined with early murine mandibular arch epithelium. Arch. Oral Biol. 32, 123-127.
20. Mundlos, S., Otto, F., Mundlos, C., Mulliken, J. B., Aylsworth, A. S., Albright, S., Lindhout, D., Cole, W. G., Henn, W., Knoll, J. H., Owen, M. J., Mertelsmann, R., Zabel, B. U. and Olsen, B. R. (1997). Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia. Cell 89, 773-779.
21. Ogawa, E., Maruyama, M., Kagoshima, H., Inuzuka, M., Lu, J., Satake, M., Shigesada, K. and Ito, Y. (1993). PEBP2/PEA2 represents a new family of transcription factor homologous to the products of the Drosophila runt and the human AML1 gene. Proc. Natl. Acad. Sci. USA 90, 6859-6863.
22. Otto, F., Thornell, A. P., Crompton, T., Denzel, A., Gilmour, K. C., Rosewell, I. R., Stamp, G. W., Beddington, R. S., Mundlos, S., Olsen, B. R., Selby, P. B. and Owen, M. J. (1997). Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development. Cell 89, 765-771.
23. Peters, H., Neubüser, A., Kratochwil, K. and Balling, R. (1998). Pax9-deficient mice lack pharyngeal pouch derivatives and teeth and exhibit craniofacial and limb abnormalities. Genes Dev. 12, 2735-2747.
24. Qiu, M., Bulfone, A., Ghattas, I., Meneses, J., Sharpe, P. T., Presley, R., Pederson, R. A. and Rubenstein, J. L. R. (1997). Role of the D1x homeobox genes in proximodistal patterning of the branchial arches: mutations of D1x-1, D1x-2, and D1x-1 and -2 alter morphogenesis of proximal skeletal and soft tissue structures derived from first and second arches. Dev. Biol. 185, 165-184.
25. Ruch, J. V., Lesot, H., Karcher-Djuricic, V., Meyer, J. M. and Mark, M. (1983). Epithelial-mesenchymal interactions in tooth germs: mechanism of differentiation. J. Biol. Buccale 11, 173-193.
26. Satokata, I. and Maas, R. (1994). Msx1 deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development. Nature Genet. 6, 348-356.
27. Thesleff, I., Vaahtokari, A., Partanen, A. M. (1995). Regulation of organogenesis. Common molecular mechanisms regulating the development of teeth and other organs. Int. J. Dev. Biol. 39, 35-50.
28. Thesleff, I., Nieminen, P. (1996). Tooth morphogenesis and cell differentiation. Curr. Opin. Cell Biol. 8, 844-850.
29. Thesleff, I. and Sharpe, P. (1997). Signalling networks regulating dental development. Mech. Dev. 67, 111-123.
30. Vaahtokari, A., Åberg, T. and Thesleff, I. (1996). Apoptosis in the developing tooth: association with an embryonic signaling center and suppression by EGF and FGF-4. Development 122, 121-129.
31. Vainio, S., Jalkanen, M., Vaahtokari, A., Sahlberg, C., Mali, M., Bernfield, M. and Thesleff, I. (1991). Expression of syndecan gene is induced early, is transient, and correlates with changes in mesenchymal cell proliferation during tooth organogenesis. Dev. Biol. 147, 322-333.
32. Vainio, S., Karavanova, I., Jowett, A. and Thesleff, I. (1993). Identification of BMP-4 as a signal mediating secondary induction between epithelial and mesenchyme tissues during early tooth development. Cell 75, 45-58.
33. Van Genderen, C., Okamura, R. M., Farinas, I., Quo, R. G., Parslow, T. G., Bruhn, L. and Grosschedl, R. (1994). Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1 deficient mice. Genes Dev. 5, 656-669.